Assiut University

This study tests a new way to guide fluid treatment in patients with septic shock (a severe infection causing low blood pressure). The goal is to see if using a non-invasive arm cuff to measure blood flow pressure can reduce the risk of acute kidney injury compared to standard ca…

This study will test a surgery called selective dorsal rhizotomy to reduce severe muscle stiffness (spasticity) caused by brain or spinal cord injury. The procedure involves cutting specific nerve roots to lower muscle tone. Researchers will enroll 32 people aged 4 and older to s…

This study looks at how well standard care works for people with a serious spinal infection called primary spondylodiscitis. About 50 patients will be followed for one year to see if the infection is cured, how much pain improves, and if any complications arise. The goal is to un…

This study tests whether injecting chemotherapy directly into pancreatic tumors using a thin, flexible tube (endoscopic ultrasound) can help people with locally advanced pancreatic cancer live longer without the disease getting worse. About 20 adults with this cancer will either …

This study tests whether a nebulized drug called dexmedetomidine can prevent dangerous blood pressure spikes when a breathing tube is placed in women with severe preeclampsia undergoing cesarean section under general anesthesia. About 100 participants will receive the treatment, …

This study tests whether a newer heart failure drug (sacubitril/valsartan) works better than an older one (captopril) in children aged 1 month to 18 years with dilated cardiomyopathy—a condition where the heart is enlarged and pumps weakly. About 70 children will receive one of t…

This study tests a drug called romiplostim in 100 children aged 1 to 18 with chronic ITP, a condition where the immune system destroys platelets, causing bleeding. The drug aims to safely increase platelet counts to safe levels for at least 6 weeks out of 48, without needing resc…

This study will test how well a special camera-guided (endoscopic) surgery can completely remove tumors in the nasal cavity and sinuses that are in difficult spots. About 25 people with these tumors will take part. The main goal is to see how often the tumor can be fully removed,…

This study looks at a new surgical technique for repairing cut finger tendons that does not require a splint after surgery. Forty adults with clean tendon cuts will have the repair and then start moving their fingers gently right away. The goal is to see if this approach leads to…

This study compares a minimally invasive procedure called POEM for treating achalasia, a swallowing disorder. It looks at two groups: patients receiving POEM as their first treatment and those who had a prior balloon dilation that failed. The goal is to see if prior balloon dilat…

This study compares two advanced artificial heart valves (SAPIEN 3 Ultra Resilia and Evolut FX) used in a procedure called TAVI to treat severe aortic stenosis. About 200 people with severe, symptomatic aortic stenosis will be randomly assigned to receive one of the two valves. T…

This study tests whether a new approach called 'woundsome revascularization'—which focuses on restoring blood flow directly to the wound area—can help save the legs of 50 people with chronic limb-threatening ischemia, the most severe form of peripheral artery disease. Participant…

This study tests whether a single injection of nanofat (processed fat tissue) can outperform either PRP injections or daily minoxidil 5% for treating male and female pattern baldness. Sixty adults aged 18-50 with confirmed androgenetic alopecia will be enrolled. The goal is to se…

This study looks at two different ways to close the skin after stoma reversal surgery in children. The goal is to see which method leads to fewer infections and better-looking scars. Fifty children will take part, and their results will be checked over three months.

This study tests two treatments—essential phospholipid and betaine HCL/L-glutamic acid—in 200 adults with metabolic fatty liver disease (MAFLD). The goal is to see which one better reduces liver fat over the treatment period. Participants must be over 18 and diagnosed with fatty …

This study looks at people with locally advanced rectal cancer who have small leftover spots in the rectum after chemoradiation. Doctors want to see if removing these spots with a scope (endoscopic resection) leads to better 1-year cancer control than simply watching them closely…

This study tests a shorter course of radiation (3.5 Gy per session for 17 sessions) for people with early-stage glottic cancer (T1-T2N0M0). The goal is to see if this approach controls the tumor as well as or better than standard longer radiation, while keeping side effects low a…

This study compares three treatments for non-genital warts: ivermectin cream alone, ivermectin cream combined with microneedling, and standard salicylic acid. About 88 people aged 11 to 80 will receive treatment every two weeks for up to three months. The goal is to see which app…

This study tests a simple surgery where a piece of the patient's own vein is wrapped around a repaired nerve in the arm. The goal is to reduce scar tissue and painful nerve growths (neuromas) that can cause long-term pain and disability. About 43 adults with recent nerve injuries…

This study compares two surgical methods to treat choanal atresia, a birth defect where the nasal passages are blocked. About 30 infants and young children will be randomly assigned to one of two procedures. The goal is to see which surgery leads to fewer re-blockages and better …

This study compares two types of cartilage grafts (thin vs thick) used to repair holes in the eardrum in adults aged 18-65. The goal is to see which graft has a higher success rate at closing the hole after 6 months. The study will also measure hearing improvement and surgery tim…

This study tests two treatments for keloids (raised scars that grow beyond the original wound). One group gets only a special freezing treatment inside the scar, and the other gets the same freezing plus injections of two medicines (5-fluorouracil and triamcinolone acetonide). Th…

This study compares three different surgical approaches for managing placenta accreta, a serious pregnancy condition where the placenta grows too deeply into the uterine wall. The goal is to find which method causes the least blood loss during delivery. The study will include 42 …

This study looks at using both a nail and a plate to fix certain hip fractures where the side wall of the bone is weak. About 17 adults with these fractures will get the combined surgery and be followed for 6 months to see how well the bone heals and if any problems occur. The go…

This study compares two types of neck surgery for people with cervical spinal stenosis, a condition where the spine narrows and presses on nerves. Researchers will look at how well each surgery improves nerve function and how often complications occur. The goal is to find which a…

This study looks at using laparoscopic (keyhole) surgery to drain pus from liver abscesses, comparing it to standard open or needle drainage. It includes 30 adults whose abscesses are large, have come back, or can't be drained by needle. The goal is to see if keyhole surgery lead…

This study looks at whether a medicine called sacubitril/valsartan can improve the heart's ability to relax and fill with blood in people with heart failure with reduced ejection fraction (HFrEF). About 70 adults will take the drug for six months and have ultrasound scans to meas…

This study looks at how well different biologic medications work for people with moderate-to-severe inflammatory bowel disease (Crohn's disease or ulcerative colitis) after one year of treatment. Researchers will track whether patients achieve remission without steroids, need few…

This phase 2 trial tests a more intense chemotherapy regimen (gemcitabine and cisplatin) given before bladder removal surgery for people with muscle-invasive bladder cancer. The goal is to see if this approach can completely eliminate the tumor before surgery. About 30 participan…

This study tests whether an extra dose of radioactive iodine can help people with a type of thyroid cancer that shows up in blood tests but not on standard scans. About 100 adults who have already had their thyroid removed and previous radiation will receive one more treatment. D…

This study tests a new surgical technique to treat pelvic organ prolapse, a condition where pelvic organs drop from their normal position. Ten women who need a hysterectomy and have at least stage 1 prolapse will receive the new suspension surgery using special ligaments. The goa…

This study tests a minimally invasive procedure that uses heat (radiofrequency or microwave) to destroy abnormal growths in the abdominal wall, such as cancer spread, desmoid tumors, or endometriosis. It includes 30 adults who cannot have surgery or choose not to. The goal is to …

This study will test whether sildenafil, a drug often used for other conditions, can improve heart function in children aged 1 to 18 with dilated cardiomyopathy, a disease that weakens the heart's pumping ability. Researchers will measure changes in the heart's ejection fraction …

This study looks at whether using a non-invasive ventilator (BiPAP) at home can improve health in people with severe COPD who have high carbon dioxide levels. Forty adults with advanced COPD will use the machine nightly and be monitored for changes in blood gas levels, breathing …

This study looks at two different surgeries for children (under 18) who have had their kneecap pop out of place more than twice. One surgery fixes only the main ligament (MPFL), while the other also fixes a second ligament (MPTL). The goal is to see which surgery works better to …

This study looks at how well a surgery called epiphyseal transfer works for people who lost part of their hip bone due to a severe infection. Researchers will check bone healing and hip function in 20 participants who had the surgery at least 5 years ago. The goal is to see if th…

This study tests whether taking the antibiotic moxifloxacin at set times over a year can lower the number of serious lung infections in adults with bronchiectasis (a chronic lung condition). Researchers will compare this approach to standard care in 140 participants. The goal is …

This study tests whether giving magnesium sulfate early through an IV can reduce dangerous narrowing of brain arteries after a traumatic brain bleed. About 50 adults with head injuries will receive the treatment within 24 hours. The goal is to see if magnesium can prevent complic…

This study compares two surgical techniques—midfoot osteotomy and 8-plate epiphysiodesis—for children aged 5 to 10 with relapsed clubfoot and a specific foot deformity called metatarsal adductus. The goal is to see which surgery provides better correction, measured by X-ray score…

This study tests a new surgical technique called Active Apex Correction (APC) for children under 10 with early onset scoliosis. The goal is to straighten the spine and allow it to grow longer. The study will include 15 children and measure spine length and curve correction after …

This study tests a surgery called lunocapitate fusion for people with wrist arthritis from an old, untreated scaphoid fracture (SNAC wrist). The surgery fuses two wrist bones to reduce pain and keep some movement. About 35 adults aged 18-60 will take part. The goal is to see if t…

This study tests whether a supervised 12-week cardiac rehabilitation program can improve heart function and quality of life in 100 adults who recently had a heart attack and received a stent. Participants will do moderate to high-intensity aerobic and resistance exercises 2-3 tim…

This study tests a surgical technique to cover deep wounds on the lower leg, ankle, heel, or foot. Doctors move a piece of skin and tissue from the outer calf to the wound, keeping it alive with a special blood supply. The study will include 30 adults and will measure how well th…

This study looks at whether a 12-hour treatment with N-Acetylcysteine works as well as the standard 21-hour treatment for children who have taken too much acetaminophen (paracetamol). The goal is to see if the shorter treatment is safer and just as effective at preventing liver d…

This study tests a fast emergency plan called the MINUTES bundle for adults with undifferentiated shock (dangerously low blood pressure from an unknown cause). The goal is to see if this 30-minute approach can restore blood pressure and improve organ function within 6 hours. Abou…

This study compares two treatments for a common elbow fracture in children (Gartland type II): casting (conservative) versus surgery. The goal is to see which approach leads to better arm function, faster recovery, and fewer complications. About 50 children aged 1-12 will partici…

This study tests a program called contingency management, which gives rewards to people with opioid use disorder for staying drug-free and following their treatment plan. Researchers will enroll 55 adults in a hospital setting to see if this approach reduces relapse risk and incr…

This study tests whether giving a rectal dose of misoprostol (a cheap, heat-stable drug) before a planned C-section, on top of standard oxytocin, can reduce blood loss during and after surgery. About 282 women having elective C-sections will be randomly assigned to receive either…

This study compares two methods of closing the skin after open appendix surgery: standard stitches versus a hidden stitch plus a small drain under the skin. The goal is to see which method leads to fewer wound infections and better healing. About 100 people having open appendix s…

This study compares two common procedures for removing small kidney stones (less than 15 mm) located in the lower part of the kidney. About 70 adults will be randomly assigned to receive either flexible ureteroscopy (a thin scope through the urinary tract) or shock wave lithotrip…

This study tests whether a cream called terbinafine hydrochloride can treat fungal ear infections (otomycosis). About 50 adults will have the cream placed in their ear every two days for two weeks. The goal is to see if symptoms like itching and discharge go away and if the fungu…

This study looks at whether ultrasound can detect complications like re-tears or infections early after hand tendon repair surgery. About 50 adults who had hand tendon surgery will get ultrasound checks. The goal is to see if ultrasound helps doctors find and treat problems faste…

This study will test if a special ultrasound technique called elastography can help doctors tell the difference between harmless and cancerous growths in the chest and digestive tract. About 35 adults will get an endoscopic ultrasound with elastography, and the results will be ch…

This study aims to see if a special ultrasound technique called shear-wave elastography can better detect tendon inflammation in people with psoriasis and psoriatic arthritis. Researchers will compare this method with standard ultrasound and also look at a protein called SIRT2 in…

This study will compare two types of scans—PET/CT and regular CT—to see which is better at finding cancer that has spread to other parts of the body in people with breast cancer. About 97 participants will be enrolled. The goal is to improve early detection and help doctors choos…

This study will test if a 10-minute fetal heart rate monitoring (CTG) test works as well as the usual 30-minute test for checking baby's health during labor. Researchers will enroll 200 low-risk pregnant women in active labor. If the shorter test proves accurate, it could reduce …

This study will use advanced CT scans to get a clearer picture of heart and blood vessel problems in children with Tetralogy of Fallot, a serious birth defect. The goal is to help doctors plan surgeries more accurately. The study will include up to 37 children aged 1 day to 12 ye…

This study looks at whether using several ultrasound techniques together during an endoscopy can more accurately tell if a thickened area in the upper digestive tract is cancerous or not. About 43 adults with unexplained thickening seen on CT or MRI scans will take part. The goal…

This study looks at how helpful endoscopy (a camera test for the stomach and intestines) is for finding the cause of digestive problems in children. Researchers will study 150 children from birth to 18 years old who need this test for issues like chronic diarrhea, vomiting, bleed…

This study will test if a new, less invasive biopsy method (transcervical true-cut biopsy) can accurately diagnose different types of uterine growths, including cancer. The goal is to see if this simple outpatient procedure can reliably tell benign from malignant masses, helping …

This study looks at whether a blood test for H. pylori bacteria and a painless stomach ultrasound can predict dangerous complications like bleeding or holes in the stomach lining. Researchers will study 230 adults with stomach symptoms to see if these simple tests can tell who ne…

This study compares triphasic CT scans with EUS-guided biopsies to see which method more accurately identifies whether pancreatic lesions are benign or malignant. About 50 adults with suspicious pancreatic growths will undergo both tests, and results will be checked against final…

This study will check how accurate a special CT scan (CT KUB) is at telling harmless kidney cysts from ones that might be cancer. About 200 people with kidney cysts found on a CT KUB will take part. Their results will be compared with ultrasound and, if needed, a contrast CT or f…

This study looks at how PET-CT scans can help doctors better understand lymphoma in people aged 60 and older. Researchers will examine scan images to find patterns that may improve diagnosis and predict outcomes. The goal is to make care more accurate for this age group.

This study aims to create and test a new scoring system called STAR, which combines ultrasound and blood tests, to quickly predict if an adult who had a blunt belly injury has internal damage. Researchers will compare the STAR score with current standard methods to see if it is m…

This study will use a special eye scan called OCT to look for early signs of retinal damage in people with diabetes who have no vision problems. Researchers will compare the eye scans of 112 diabetic participants with healthy controls to see if OCT can detect changes before sympt…

This study will check how well an ultrasound scoring system called O-RADS can tell if an ovarian mass is cancerous or not. About 80 women aged 18 to 70 with an ovarian cyst or mass will get standard care, including ultrasound and possibly surgery. The goal is to see if O-RADS mat…

This study will use a thin, pressure-sensitive probe (anorectal manometry) to measure how the muscles and nerves in a child's bottom work. The goal is to find specific problems, like poor muscle coordination or reduced sensation, in 54 children aged 4-18 with chronic constipation…

This study looks at better ways to diagnose nerve damage caused by diabetes. Researchers will use nerve tests and ultrasound in 75 adults with diabetes and healthy volunteers. The goal is to find nerve problems earlier so patients can get the right care sooner.

This study looks at whether a standard chest X-ray can reliably detect congenital heart disease in newborns. Researchers will compare X-ray results with the gold-standard echocardiogram in 60 babies admitted to the NICU. If successful, chest X-rays could help doctors diagnose hea…

This study looks at whether mammograms and ultrasounds can accurately predict the molecular subtype of breast cancer (like Luminal A, HER2-enriched, or triple-negative) without needing a biopsy. Researchers will compare imaging features to standard tissue tests in 122 women with …

This study looks at 51 children with portal hypertension to see if non-invasive tests (like blood counts and spleen size) can accurately predict the presence and severity of esophageal varices—enlarged veins that can bleed. The goal is to reduce the need for invasive endoscopy an…

This study will test whether combining standard MRI with two advanced imaging techniques—MRI volumetry and diffusion tensor imaging—can more accurately locate the seizure-causing area in people with temporal lobe epilepsy. Researchers will compare these scans with those from heal…

This study will check if a non-invasive scan called FibroScan with CAP can accurately measure fat in the liver, compared to the standard liver biopsy. It involves 100 living liver donors. If the scan works well, future donors might avoid the risks of a biopsy.

This study looks at whether a substance in the blood called sCD163 can help doctors find HELLP syndrome early in pregnancy. HELLP is a rare but serious condition that can harm the liver and blood. Researchers will compare sCD163 levels in 70 pregnant women—some with HELLP and som…

This study looks at whether a new scoring system (called the Mansoura score) can accurately predict a serious infection called spontaneous bacterial peritonitis (SBP) in people with liver cirrhosis and fluid buildup in the belly. The goal is to identify the infection early withou…

This study checks if a new physical exam test (Said's test) can accurately diagnose biceps tendon injuries in the shoulder. About 144 adults with shoulder pain and healthy volunteers will be examined by two doctors using the new test and standard tests. Results will be compared t…

This study looks at whether using a tiny camera to look inside the gut (endoscopy) can find hidden causes of poor growth in children aged 6 months to 18 years. About 50 kids with failure to thrive and possible gut symptoms will get an endoscopy. The goal is to see how well the sc…

This study aims to create a better way to tell the difference between two serious pregnancy complications: placenta accreta spectrum and uterine scar dehiscence. Researchers will use 2D and 3D ultrasound to examine 50 pregnant women in their third trimester who have a low-lying p…

This study will follow 46 people with stage III rectal cancer who have already finished treatment. Researchers want to see if PET-CT scans can accurately detect cancer recurrence and help guide treatment choices. Participants will be observed for 5 years as part of their routine …

This study will check if an Arabic version of the SAMANTA questionnaire can reliably identify heavy menstrual bleeding in women aged 15 to 45. Heavy periods affect up to half of women and can cause anemia and lower quality of life. The goal is to provide a simple, low-cost tool f…

This study will check if two simple blood test ratios (AST/ALT and MPV/platelet count) are different in women with breast cancer compared to healthy women. Researchers will look at medical records of 110 people to see if these ratios can help diagnose breast cancer. The goal is t…

This study will compare two imaging methods—18F-PSMA PET/CT and standard CT—in men with prostate cancer. The goal is to see if the newer scan is better at finding cancer initially, tracking how well treatment works, and detecting cancer that has come back. About 59 participants w…

This study tests a new ultrasound technique to detect fetal anemia earlier and more accurately. Researchers will compare a new measurement (acceleration time) with the standard method in 20 fetuses with anemia or high cardiac output. The goal is to improve early diagnosis and tim…

This study looks at whether measuring two proteins in the blood, Talin-1 and Cripto-1, can help diagnose colorectal cancer. Researchers will compare levels in 70 newly diagnosed patients and healthy people. The goal is to see if these markers work better than the current standard…

This study looks at whether a special MRI scan can tell the difference between two causes of stroke: hardening of brain arteries (atherosclerosis) and inflammation of blood vessels (vasculitis). About 46 people who recently had a stroke will get this scan. The goal is to help doc…

This study looks at whether the triglyceride-glucose (TyG) index, a simple calculation from routine blood tests, can predict insulin resistance in people with pre-diabetes and chronic kidney disease. Researchers will enroll 60 adults to compare the TyG index against standard meth…

This study will test if a special type of MRI scan, called arterial spin labelling (ASL), can accurately determine how aggressive a brain tumor is in children. Doctors will compare the scan results with the tumor's actual grade from tissue analysis. The goal is to see if this non…

This study will check if two blood markers, MPV and SIRI, can help doctors diagnose and predict the course of acute coronary syndrome (heart attack or unstable angina). Researchers will measure these markers in 300 adults admitted within 24 hours of symptoms. The goal is to see i…

This study will test whether artificial intelligence (AI) can accurately tell the difference between inflammatory arthritis (like rheumatoid arthritis) and degenerative arthritis (like osteoarthritis) in people aged 60 and older. Researchers will compare the AI's analysis of X-ra…

This study looks at how often an upper endoscopy (a camera test to look inside the stomach) finds a clear cause for long-term belly pain in children aged 6 to 18. About 100 kids with chronic abdominal pain will get the procedure. The goal is to see how useful this test is for fin…

This study looks at whether measuring two specific genes (NEAT1 and ANRIL) in a blood sample can help diagnose inflammatory bowel disease (IBD) without needing a colonoscopy. Researchers will enroll 62 newly diagnosed IBD patients and compare their gene levels to their symptoms a…

This study looks at whether a simple chest ultrasound can tell the difference between two types of fluid buildup around the lungs, without needing a needle. Researchers will compare ultrasound images to standard lab tests in 90 adults. If successful, this could make diagnosis saf…

This study tests whether giving anti-epileptic drugs right after a traumatic brain injury can prevent seizures. About 70 adults with moderate to severe head injuries will receive either the drug or a placebo. Researchers will track seizure episodes and overall recovery for 3 mont…

This study tests two techniques—a pericardial window and a retro-cardiac drain—to prevent atrial fibrillation and other heart sac complications after coronary artery bypass surgery. About 122 adults with good heart function will be randomly assigned to one method. The goal is to …

This study tests whether placing vancomycin powder inside the surgical wound during brain shunt placement can prevent infections in children with hydrocephalus. About 164 children will be randomly assigned to receive the powder or standard care. The goal is to see if this simple,…

This study tests a non-invasive brain stimulation technique called rTMS in 80 children and teens (ages 6-19) with ADHD or autism. Participants will receive either real or sham (fake) stimulation over 3 weeks to see if it safely reduces core symptoms. The goal is to explore a pote…

This study tests two ways to manage pain in 66 boys aged 1-6 years having hypospadias repair. One method is a standard caudal block; the other is a newer sacral block. Both use a medicine called dexmedetomidine to extend pain relief. The goal is to see which approach provides lon…

This study compares two ways to realign the knee after surgery for osteoarthritis in people with bow-legged legs. One method uses the knee's natural angle (kinematic), the other uses a straight mechanical angle. About 100 adults with painful, arthritic knees that haven't improved…

This study tests whether adding phenol injections to standard botulinum toxin (Botox) treatment works better for reducing arm stiffness in stroke survivors. About 60 adults who had a stroke at least 6 months ago will receive either the combined therapy or Botox alone. The goal is…

This study compares three treatments for pitted acne scars: a minor skin procedure called subcision alone, or subcision combined with either a fractional CO2 laser or platelet-rich plasma (PRP). The goal is to see which combination improves scars the most. The study will enroll 4…

This study tests whether taking tranexamic acid pills along with a skin needling treatment that delivers glutathione works better for melasma than either treatment alone. About 42 women with facial melasma will be enrolled. The goal is to reduce the dark patches and improve how p…

This study compares two surgical techniques for removing kidney stones larger than 2 cm. One method uses a flexible tube with suction, and the other uses direct suction through the scope. The goal is to see which approach is faster, removes more stone, has fewer complications, an…

This study compares two gels applied inside the nose to see which better reduces how often nosebleeds happen. About 162 people who get nosebleeds at least twice a month will use either a plant-based gel (B-sitosterol) or plain petroleum jelly (Vaseline). The goal is to find a sim…

This study will compare two types of general anesthesia—total intravenous anesthesia (TIVA) and inhaled anesthesia—to see which one better prevents nausea and vomiting after laparoscopic obstetric surgery. About 98 women aged 18 to 50 having elective laparoscopic procedures will …

This study compares three treatments for facial acne scars: nanofat injection alone, nanofat plus platelet-rich fibrin, and nanofat plus microneedling. 42 adults with moderate to severe scars will receive treatment on both cheeks. The goal is to see which combination works best a…

This study tests whether a sodium bicarbonate enema can help relieve constipation and reduce harmful waste products (uremic toxins) in people with chronic kidney disease (CKD). The idea is to use the gut as an extra route to remove toxins that damaged kidneys can't clear. The stu…

This study tests whether adding magnesium sulfate or lidocaine to a standard sedative (dexmedetomidine) better prevents coughing after functional endoscopic sinus surgery. Coughing after this surgery can cause bleeding and slow recovery. About 102 adults will be randomly assigned…

This study tests whether potassium citrate, a urine alkalinizer, can relieve painful urination, urgency, and frequency in women aged 18-50 with uncomplicated UTIs. Fifty participants will take either potassium citrate or the antibiotic nitrofurantoin for 7 days. Researchers will …

This study compares two surgical approaches for degenerative lumbar spinal stenosis, a condition that causes back and leg pain due to narrowed spinal canals. Researchers will follow 56 adults over 40 who haven't improved with non-surgical treatments. One group will receive a less…

This study tests whether placing a small drain in the belly to let out leftover gas can reduce shoulder pain after gynecologic laparoscopy (keyhole surgery). The leftover gas can irritate the diaphragm and cause pain in the shoulder. About 124 women having this surgery will be ra…

This study compares two surgical techniques for treating painful disc problems in the lower back. About 30 adults who have not improved with other treatments will receive either two straight cages or one banana-shaped cage during lumbar fusion surgery. Researchers will measure pa…

This study looks at two medicines, Dexmedetomidine and Ketamine, added to a standard pain block for children aged 1 to 6 years after hip surgery. The goal is to see which one provides better pain relief, lasts longer, and reduces the need for extra pain medicine. The study will e…

This study tests whether dexmedetomidine or midazolam is better at preventing shivering in trauma patients undergoing lower leg surgery with spinal anesthesia. Shivering is common after spinal anesthesia and can cause discomfort and complications. The trial will enroll 100 adults…

This study tests whether injecting platelet-rich plasma (a concentrated part of your own blood) into the vocal folds can improve voice quality and daily life for people with vocal fold sulcus, scar, or atrophy. About 48 participants aged 10 and older will receive the injection an…

This study compares virtual reality (VR) therapy with traditional vestibular rehabilitation for adults aged 18-70 who have had dizziness for more than 3 months due to inner ear problems. The goal is to see if VR can improve balance and reduce dizziness better than standard exerci…

This study tests two medicines, dexmedetomidine and lidocaine, to see which one helps place a breathing mask (laryngeal mask) more easily in children aged 2-12 having elective surgery. The goal is to improve first-attempt success and reduce coughing or other breathing problems. S…

This study tests a new gel made with spironolactone against a standard acne gel (adapalene) in 40 people with mild to moderate acne. Each person will use the spironolactone gel on one side of their face and the adapalene gel on the other, so the results can be compared directly. …

This study compares two surgical implants used in neck surgery for cervical degenerative disc disease. One implant has built-in screws for extra stability, while the other is a traditional cage. Researchers want to see which one leads to better bone fusion, pain relief, and neck …

This study looks at two different drug combinations given before gallbladder surgery to prevent nausea and vomiting afterward. It involves 102 women who are non-smokers and in good health. The goal is to find which combination works better to reduce sickness and the need for extr…

This study tests whether avoiding opioids during gallbladder surgery can reduce pain and nausea after the operation. Researchers will compare opioid-free anesthesia to standard opioid-based care in 110 adults aged 18 to 60. The goal is to see if this approach improves recovery an…

This study compares two ways to numb the shoulder for surgery. The standard method can sometimes weaken breathing muscles. The new method uses a different nerve block combination plus clonidine, aiming to control pain just as well but with fewer breathing side effects. Sixty adul…

This study tests whether injecting platelet-rich plasma (PRP) into the wound after fistulotomy helps it heal faster. About 70 adults with simple anal fistula will be randomly assigned to get PRP or standard care. The goal is to see if PRP reduces pain and shortens recovery time.

This study looks at whether placing children in a specific position when their breathing tube is removed after tonsil/adenoid surgery can prevent dangerous drops in oxygen levels. About 262 children aged 2-10 will be randomly assigned to different positions. The goal is to find a…

This study tests a new cream containing apremilast nanoparticles for treating mild to moderate plaque psoriasis. About 36 adults will use either the new cream, a standard steroid cream, or both for 12 weeks. The goal is to see if the new cream reduces psoriasis symptoms with fewe…

This study compares a new topical gel containing dutasteride to a standard triple-combination gel (clindamycin, benzoyl peroxide, adapalene) for treating facial acne in adults over 18. Researchers will measure how well each treatment clears acne lesions and improves quality of li…

This study compares two gels—hyaluronic acid and petroleum jelly—to see which stops nosebleeds faster and prevents them from coming back. About 50 people with common, non-serious nosebleeds will take part. The goal is to find a simple, effective treatment for this frequent proble…

This study compares different surgical techniques for treating severe gynecomastia (enlarged male breasts) in 45 men aged 18 to 60. The goal is to find which method gives the best cosmetic results and highest patient satisfaction. Participants will have one of four surgical appro…

This study compares two tools used during thyroid surgery: LigaSure and bipolar diathermy. The goal is to see which one leads to shorter surgery time, less pain, and fewer complications like low calcium levels. Thirty adults having partial or total thyroid removal will take part.

This study tests whether taking two erectile dysfunction drugs together (tadalafil 2.5mg plus sildenafil 25mg) works better than taking a higher dose of just one drug (tadalafil 5mg). About 142 men aged 18 to 70 with ED for at least 3 months will participate. The goal is to see i…

This study compares early task-oriented rehabilitation (practicing meaningful daily activities) with traditional physiotherapy in 158 adults who had a stroke within the past 48 hours. The goal is to see which approach leads to better motor function and quality of life after 3 mon…

This study looks at whether adding a special tape to standard ACL surgery helps people recover faster. About 114 people aged 15 to 50 with an ACL tear will be split into two groups: one gets the tape, the other doesn't. Both will follow an accelerated rehab program. Researchers w…

This study looks at whether caffeine therapy can help stabilize the heart and blood pressure of preterm babies (born before 37 weeks) who have apnea (pauses in breathing). Researchers will monitor 40 infants in the NICU, measuring changes in blood pressure, heart rate, and blood …

This study tests a 3-month rehabilitation program for people with stable COPD. The program includes exercises done both at the hospital and at home. Researchers want to see if it helps patients walk farther and feel better. About 70 adults over age 40 with moderate to severe COPD…

This study tests a cosmetic procedure where a person's own belly fat is injected into the penis to make it thicker. It will enroll 25 men aged 21-60 who are unhappy with their size and have a flaccid girth under 11 cm. Researchers will measure changes in girth and check fat survi…

This study tests a breast lift surgery that uses a woman's own skin and fat to reshape and add fullness to sagging breasts. The procedure aims to avoid implants by using an internal bra made from the patient's tissue plus fat grafting. The study will enroll 28 women aged 18-50 wi…

This study tests whether giving lidocaine through a vein during gallbladder surgery can reduce inflammation and pain, and help the gut start working again sooner. About 90 adults having planned laparoscopic gallbladder removal will be randomly assigned to receive either lidocaine…

This study compares two drugs, dexmedetomidine and magnesium sulphate, added to standard spinal anesthesia for hip surgery. The goal is to see which provides better pain control and faster recovery. 92 adults undergoing elective hip fixation will be randomly assigned to receive o…

This study tests whether taking a daily 5 mg tadalafil pill can reduce urinary symptoms like leakage and urgency after prostate surgery for enlarged prostate (BPH). About 40 men who are having surgery will be randomly assigned to receive tadalafil or a placebo for 12 weeks after …

This pilot study will test whether low-intensity shockwave therapy can safely improve blood flow and ease symptoms in 30 men with erectile dysfunction caused by blood vessel problems. Participants will receive treatment using a special device, and researchers will monitor for sid…

This study tests if inflating a small balloon in the stomach outlet during surgery can prevent delayed stomach emptying, a common problem after pancreatic tumor removal. About 70 adults having this surgery will be randomly assigned to get the balloon procedure or standard surgery…

This study compares two medicines, dexmedetomidine and nalbuphine, added to a standard numbing shot for arm surgery. The goal is to see which combination provides longer pain relief after the operation. 66 adults having elective upper arm surgery will take part. The study is not …

This study compares two minimally invasive treatments for chronic plantar fasciitis, a common cause of heel pain. One uses pulsed radiofrequency to calm nerves, the other uses steroid injections to reduce inflammation. The goal is to see which provides better pain relief in adult…

This study tests whether rinsing the surgical area with a mix of ketamine and a standard numbing medicine (bupivacaine) can better control pain after gallbladder removal than the numbing medicine alone. Sixty adults having laparoscopic gallbladder surgery will be randomly assigne…

This study will test a special recovery plan (called ERAS) for women who need an emergency C-section. The plan includes better pain control, early movement, and quicker return to eating. Researchers will track 100 women to see if this approach reduces pain and speeds up recovery …

This study tests whether lidocaine, ketamine, or both given through a vein can safely reduce pain in people with orofacial pain that hasn't responded to other treatments. About 105 adults will be randomly assigned to one of three groups and followed for 6 months. The goal is to f…

This study tests a new treatment for burn scars on the chest, shoulders, and back. Doctors will take a small amount of fat from the patient's belly or thigh, process it into a liquid rich in healing cells, and inject it into the scar. The goal is to improve the scar's color, thic…

This study looks at whether it is safe and effective to remove kidney stones in one procedure, even when kidney function is reduced. About 60 adults with a blocked ureter and elevated creatinine levels will undergo immediate ureteroscopy without a prior stent. The goal is to see …

This study looks at two surgical approaches to treat severe hand or underarm sweating. The goal is to see if operating on one nerve level (T3) causes less unwanted sweating in other body areas compared to operating on two levels (T3-4). About 46 people aged 6 and older with prima…

This study compares two drug combinations—dexmedetomidine versus fentanyl plus midazolam—to see which better controls stress (like heart rate spikes) during laparoscopic gallbladder removal. About 50 adults undergoing this surgery will be randomly assigned to one of the two group…

This study compares two medications, dexmedetomidine and fentanyl, given during general anesthesia for major abdominal cancer surgery. The goal is to see which drug better maintains heart function and stability during and after the operation. Seventy adults undergoing elective su…

This study tests whether breathing in N-acetylcysteine (a mucus-thinning drug) works better than getting it through a vein for people with bronchiectasis who are in the hospital for a flare-up. About 70 adults will take part, and researchers will measure how thick the mucus is, h…

This study compares two medicines, propofol and lidocaine, to see which better reduces agitation when children wake up from tonsillectomy surgery. About 82 children aged 4 to 7 will take part. The goal is to find a way to make recovery smoother and less distressing for young pati…

This study looks at a surgery called calcaneal osteotomy for people with long-lasting heel pain (plantar fasciosis) that hasn't improved with other treatments. The surgery aims to reduce tension on the plantar fascia without cutting it. Researchers will measure pain and foot func…

This study looks at whether using a larger or smaller amount of fluid injected around the median nerve in the wrist can better relieve pain and symptoms of carpal tunnel syndrome. The treatment, called hydrodissection, uses ultrasound guidance to separate the nerve from surroundi…

This study looks at whether wearing a hip cast for 6 weeks works as well as 12 weeks after hip surgery in children with developmental dysplasia of the hip (DDH). About 40 children aged 18 months to 6 years will take part. The goal is to see if a shorter cast time can reduce compl…

This study will compare two sedative drugs, dexmedetomidine and ketamine, given through a vein to help men relax and stay comfortable during varicocelectomy surgery done with spinal anesthesia. The goal is to see which drug provides better sedation with fewer side effects like sl…

This study compares two types of nerve blocks (ESPB and QLB) to see which provides better pain relief after kidney surgery in children aged 2-12. The goal is to reduce pain and the need for extra pain medication. 100 children will take part, and the study will measure how long pa…

This study looks at whether a superficial cervical plexus block can help control pain after maxillofacial surgeries (like procedures on the jaw, neck, or ear). About 70 adults will receive either the block or standard care. The main goal is to see how long it takes before they ne…

This study tests whether adding dexmedetomidine to a standard numbing medicine (bupivacaine) can improve pain control after upper abdominal cancer surgery. About 54 adults undergoing surgeries like stomach or liver removal will receive an ultrasound-guided nerve block. The goal i…

This study will look at medical records of 770 women who had C-sections in two hospitals in Assiut, Egypt, during 2026. The goal is to find out which groups of women are most likely to have C-sections and compare practices between the hospitals. The results may help reduce unnece…

This study looks at whether a specific cholesterol ratio (NHHR) is linked to kidney damage in people with diabetes. Researchers will measure this ratio and kidney function in 84 adults with diabetes. The goal is to see if NHHR can help identify those at risk for diabetic kidney d…

This study will enroll 66 adults with liver cancer who are scheduled for either TACE or microwave ablation. Researchers will use CT scans to measure tumor volume before and after treatment to see if this method can better assess how well the therapy worked. The goal is to improve…

This study looks at a lesser-known bacteria called Providencia that can cause urinary tract infections (UTIs). Researchers will collect samples from 241 patients to identify these bacteria, test which antibiotics work against them, and find out what makes them resistant to drugs.…

This study looks at stored tumor samples from 100 people who had bladder cancer surgery. Researchers want to see if the mix of cancer cells, supportive tissue, and immune cells can help predict who will do better after surgery. The goal is to find new ways to personalize treatmen…

This study will track 225 adults with end-stage kidney disease who are on regular dialysis (three times a week) to see if missing a session raises the chance of heart problems like heart attack, heart failure, or stroke within 72 hours. The goal is to understand the risks of miss…

This study looks at whether changes in blood flow can quickly tell doctors if a nerve block for arm surgery is working. About 50 adults having arm surgery will be monitored. The goal is to find a simple way to confirm the block is effective, which could improve pain control and r…

This study looks at vitamin D levels in 63 critically ill children (1 month to 12 years) admitted to the ICU with severe breathing infections. Researchers will measure vitamin D and check if low levels are linked to more severe illness or higher risk of death. The goal is to bett…

This study will look at 100 adults with acute pancreatitis to see if certain scores calculated from routine blood tests can help predict how severe the disease is and what the outcome might be. Researchers will compare these scores to the standard way of classifying pancreatitis …

This study looks for Helicobacter pylori (a stomach bacteria) in 200 adults with metabolic fatty liver disease. Researchers want to find out how many of these patients also have the bacteria, which could help improve treatment and quality of life. Participants will provide a stoo…

This study looks at children with joint problems that are not caused by inflammation, such as stiffness or deformity. The goal is to find the real underlying causes using exams, lab tests, and imaging. By doing this, doctors hope to avoid misdiagnosis and unnecessary treatments. …

This study will watch about 65 children, ages 1 to 24 months, who are in the hospital for bronchiolitis—a common lung infection that can make it hard to breathe. Researchers will collect information from parents and medical records to find out which factors, like premature birth …

This study will check 100 adults on dialysis to see how often they have thyroid issues, abnormal cholesterol, or high uric acid. Researchers want to understand how these conditions are linked in people with kidney failure. The goal is to gather information, not to test a new trea…

This study will follow 100 adults with diabetes and foot ulcers to see how non-vascular factors like nerve damage, infection, and poor blood sugar control affect ulcer severity and healing. Researchers will track ulcer size and recurrence over one year. The goal is to identify mo…

This study will measure how many people with knee osteoarthritis also have sarcopenia (age-related muscle loss). Researchers will assess muscle mass, strength, and physical performance in 224 adults aged 40 and older in Upper Egypt. They will also look at nutrition and quality of…

This study looks at 160 women who come to Assiut University Hospital with physical injuries. The goal is to find out how many of these injuries are caused by violence and to understand the types of injuries they have. Researchers will also check how well doctors write forensic re…

This study will compare two types of central catheters used in newborns: umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs). Researchers will track complications, how long each catheter lasts, and rates of bloodstream infections. The goal is to …

This study involves 80 men with non-obstructive azoospermia (no sperm in their semen due to low sperm production). Researchers will check how often sperm can be successfully retrieved from a single testis during a procedure called microscopic testicular sperm extraction (TESE) pe…

This study looks at whether a non-invasive small bowel ultrasound combined with a blood test for tissue transglutaminase (tTG) antibodies can accurately measure celiac disease activity. Researchers will enroll 140 people aged 2 and older, including newly diagnosed patients, those…

This study will test new scoring methods to predict complications and death risk in 100 adults hospitalized with liver cirrhosis. Researchers will compare these new scores to standard ones to see which are more accurate. The goal is to help doctors identify high-risk patients ear…

This study aims to find out how common schistosomiasis is among people in Assiut, Egypt, and what factors increase the risk of infection. Researchers will test urine and stool samples from 359 participants using a microscope. The goal is to better understand the disease in this r…

This study looks at Candida fungi that cause infections in patients with weakened immune systems in the hematology ICU. Researchers will collect samples from 300 patients to see how these fungi form protective biofilms and resist antifungal drugs. The goal is to find patterns tha…

This study surveys 350 married women aged 18-49 in Assiut, Egypt to learn what they know and think about different birth control methods, and which ones they actually use. Researchers will also explore social and economic reasons that affect their choices. The goal is to provide …

This study aims to understand prediabetes in young adults and how it relates to other health issues like insulin resistance, high cholesterol, and fatty liver. Researchers will study 120 people with prediabetes at Assiut University Hospital through exams and lab tests. The goal i…

This study will follow 200 children with epilepsy to find out why some don't respond to standard seizure medicines. Researchers will look at brain scans, EEG patterns, and medical history to spot early clues. The goal is to identify resistant cases sooner and explore alternative …

This study looks at how often people develop a new fatty liver disease (MASLD) after receiving a liver transplant. Researchers will follow 100 adults who had a liver transplant for reasons other than MASLD. The goal is to find out how common this condition is and what factors, li…

This study will use a safe ultrasound technique to measure blood flow in the brains of 200 stable newborns, both full-term and premature. The goal is to find normal differences in blood flow patterns based on how early a baby is born. These reference values could help doctors spo…

This study looks at whether low vitamin D levels are linked to higher insulin resistance in people with type 2 diabetes. Researchers will measure insulin resistance using a simple blood test called the triglyceride-glucose index. About 165 adults with type 2 diabetes will partici…

This lab study looks at whether verapamil, a common blood pressure medicine, can make antibiotics work better against drug-resistant bacteria. Researchers will test bacteria samples from 100 cancer patients to see if adding verapamil helps kill superbugs. The goal is to find new …

This study is creating a tool to help researchers use artificial intelligence (AI) ethically in their work. About 200 people who have experience with research or AI will test the tool. The goal is to make sure AI is used responsibly in science, not to treat any disease.

This study aims to see if routine blood tests can help predict how severe a heart attack is and what the future health outcomes might be, especially for people with diabetes. Researchers will follow 1,000 patients having emergency heart artery opening procedures. The goal is to f…

This study aims to find out how often liver cancer (HCC) ruptures, what factors increase the risk, and how long patients live after such a rupture. Researchers will review medical records of 100 adults diagnosed with a ruptured HCC at Assiut University Hospitals over the past fiv…

This study looks at the eating habits of 50 pregnant women with inflammatory bowel disease (IBD). Researchers want to see if better diet quality is linked to healthier pregnancies and baby growth. The goal is to find nutritional gaps and improve dietary advice for these mothers.

This study compares two similar brain diseases: multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Researchers will measure specific proteins in the blood of 100 participants to find differences that could help doctors diagnose and manage each condition m…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will answer pain and disability questionnaires and get a physical exam. Researchers will compare these results with their MRI scans to he…

This study looks at whether low magnesium levels are linked to sleep problems in adults with major depression. Researchers will measure magnesium in the blood and ask 90 participants about their sleep and mood. The goal is to better understand the connection, not to test a treatm…

This study looks at how sleep disorders and problems with the body's automatic functions (like heart rate control) are linked in older adults with heart disease. Researchers will study 210 patients aged 65 and older to find common risk factors and understand how these issues affe…

This study compares two methods—ultrasound of the inferior vena cava and central venous pressure monitoring—to see which better guides fluid treatment in septic shock patients. Researchers will enroll 70 adults in the emergency department to measure how well each method predicts …

This study compares two common techniques—direct trocar insertion and Veress needle insertion—for starting gynecologic laparoscopy in people who have had prior abdominal surgeries. The goal is to see which method is faster and safer for entering the abdomen. About 88 adults with …

This study looks at how a small ligament inside the hip joint affects treatment for developmental hip dysplasia (DDH) in children. Researchers will include 50 children whose previous treatments failed. The goal is to better understand which patients benefit most from hip-preservi…

This study looks at whether lead exposure plays a role in multiple sclerosis (MS). Researchers will measure lead levels, oxidative stress markers, and DNA changes in blood samples from 140 people with MS and healthy controls. The goal is to understand how lead might influence MS …

This study aims to find out how often hemolytic uremic syndrome (HUS) occurs in children under 18 admitted to Assiut University Children's Hospital. Researchers will look at medical records of 50 children diagnosed with HUS to describe their symptoms, lab results, and other featu…

This study observes 30 adults on a heart-lung machine (VA-ECMO) for severe heart failure. Researchers will measure brain oxygen levels and compare them with blood flow and heart function data. The goal is to learn how these factors relate, not to test a new treatment. Participant…

This study looks back at the medical records of 200 women treated for gynecological cancers (like ovarian or cervical cancer) at Assiut University Hospital between 2022 and 2025. Researchers will calculate how long patients lived after diagnosis and compare those numbers to survi…

This study will follow 100 children aged 1-18 with myocarditis (heart muscle inflammation) to see how different forms of the disease affect their recovery. Researchers will track symptoms, treatments, and heart function over one year. The goal is to better understand the disease …

This study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they recover after surgery. Participants will have ultrasound scans, semen tests, and testosterone checks before and three…

This study looks at whether certain blood markers (like NLR, PLR, PNI, and SII) can predict how severe sepsis will be and who might die from it. Researchers will compare these markers to standard scoring systems (SOFA and APACHE) in 61 ICU patients. The goal is to find a simpler,…

This study uses CT scans to see how a deviated (crooked) nasal septum affects the size of the maxillary sinuses and whether it leads to sinus infections. Researchers will compare the sinus on the crooked side with the other side in 120 adults. No treatment is given—this is an obs…

This study looks at how common violence is among married women struggling with infertility in Egypt. Researchers will survey 233 women aged 18-45 who are seeking infertility treatment. The goal is to understand the link between infertility and domestic violence, and to help creat…

This study looks at whether measuring belly fat with CT scans can help predict how well biologic therapy works for people with ulcerative colitis. Researchers will follow 200 adults for 6 months to see if changes in fat around the belly are linked to treatment success. The goal i…

This study will check if two proteins found in spinal fluid (NSE and S100B) can help doctors predict how well children with brain swelling (encephalitis) will recover. About 90 children aged 1 month to 18 years will join. The goal is to see if these lab tests are better than curr…

This study looks at how to better measure the energy needs of 187 critically ill patients in the ICU. Researchers will use a special device called indirect calorimetry to see how many calories each patient actually burns. The goal is to compare these measurements with standard fo…

This study looks at 150 adults aged 40-70 who are at medium risk for heart disease. Researchers want to see if higher levels of a blood fat called lipoprotein(a) are linked to more calcium buildup in the heart arteries, as seen on a CT scan. Participants will get a CT scan and gi…

This study looks at 50 adults with sepsis or septic shock in the ICU to see if giving beta-lactam antibiotics over a longer period (extended infusion) works better than giving them all at once (intermittent dosing). The main goal is to check survival rates at 90 days and how well…

This study compares two ways to check how active ulcerative colitis (UC) is: a simple belly ultrasound versus a colonoscopy. Researchers will enroll 200 adults with active UC to see if the ultrasound scores match the colonoscopy results. If they do, patients might one day avoid r…

This study looks at whether changes in blood sugar levels before giving antibiotics can help predict how serious sepsis will be and what outcomes patients in the ICU might have. Researchers will monitor 105 adults with sepsis, tracking their glucose levels and a new measure calle…

This study looks at how the liver changes in size after radiation therapy for cancers in or near the liver. Researchers will use CT scans taken before and after treatment to measure liver volume changes. The goal is to better understand radiation's effect on the liver and help do…

This study examines stored tumor tissue from 70 people with a common type of breast cancer (ER-positive, HER2-negative) who received hormone therapy. Researchers want to see if certain proteins in the tissue are linked to whether the cancer responds to treatment or becomes resist…

This study looks at two ways to fix severe breaks in the lower spine and pelvis. One method uses a large incision, the other uses smaller cuts. Researchers will review medical records of 60 adults to see which approach leads to better healing, fewer problems, and a faster return …

This study will check if a special heart ultrasound measurement (left atrium strain) can predict serious problems in the hospital for people who had a major heart attack and got a procedure to open blocked arteries. About 135 adults will be watched to see if this test can warn ab…

This study looks at past cases of children with retinoblastoma, a rare eye cancer, to see how well three treatments—radioactive plaque, freezing therapy, and laser therapy—worked after initial chemotherapy. Researchers will review records of 150 patients treated in Egypt to find …

This study will compare two methods—the Bishop score (a physical exam) and cervical length measured by ultrasound—to see which better predicts whether labor induction will lead to a vaginal delivery within 24 hours. It will involve 88 first-time mothers with a single baby at full…

This study aims to see if a protein called Tim-3 on certain white blood cells (neutrophils) can help doctors measure how active ankylosing spondylitis (AS) is in a patient. Researchers will compare Tim-3 levels with standard inflammation markers and MRI scans of the spine and hip…

This study uses safe, non-invasive ultrasound to measure pelvic floor changes in women who have given birth. Researchers will compare women who had vaginal deliveries with those who had C-sections. Participants fill out a short questionnaire and have a pelvic exam. The goal is to…

This study looks at whether high uric acid levels can help predict if kidney disease gets worse in people with prediabetes. Researchers will follow 150 adults with prediabetes and early-stage kidney disease for changes in kidney function. The goal is to find a simple way to ident…

This study looks for parasitic infections in 285 people with blood disorders like anemia, leukemia, or lymphoma at Assiut University Hospitals. Researchers want to understand how common these infections are and how they affect patients. The goal is to improve screening and care f…

This study looks at hormone changes in children aged 5 to 18 with simple obesity (caused by eating more calories than the body uses). Researchers will measure levels of hormones like insulin, leptin, and cortisol to see how often imbalances occur. No treatment is given—the goal i…

This study will track 139 newborns who have seizures in their first month of life while in the NICU. Doctors will record what the seizures look like, run tests to find the cause, and see how the babies do during their hospital stay. The goal is to gather local data to help doctor…

This study will follow 25 children diagnosed with acute disseminated encephalomyelitis (ADEM), a rare brain inflammation, to find out what factors predict recovery. Researchers will track how many children fully recover and how many have a relapse. The goal is to better understan…

This study will use 2D and 3D ultrasound to measure vaginal laxity and bladder neck descent in 150 women who have given birth. The goal is to better understand how childbirth affects the pelvic floor. Participants will not receive any treatment, only observation and imaging.

This study looks at whether a special heart function test, called the myocardial performance index (MPI), can help doctors make better decisions when managing fetal anemia. Researchers will enroll 15 pregnant women whose babies have anemia from blood type incompatibility or parvo…

This study looks back at 300 women treated for placenta accreta (when the placenta grows too deeply into the womb) over the last 10 years at a women's hospital in Egypt. Researchers will compare standard surgery (removing the womb) with newer techniques that aim to stop bleeding …

This study looks at whether the width of a specific eye tendon affects how well surgery works for people with crossed eyes (esotropia). Researchers will measure the tendon during surgery in 28 patients and compare it to the amount of correction achieved. The goal is to help surge…

This study looks at whether low vitamin D levels are linked to more active inflammatory bowel disease (IBD) in 100 adults. Researchers will measure vitamin D in the blood of people with Crohn's disease or ulcerative colitis and compare it to their disease activity. The goal is to…

This study compares two scoring methods (STUMBL and TTSS) to see which better predicts complications and death in adults with blunt chest wall trauma. Researchers will enroll 124 participants and track outcomes like pneumonia, need for a breathing machine, ICU stay, and death. Th…

This study looks at how well heart device implant procedures at one hospital match official European guidelines. Researchers will track 200 adults getting a heart device for the first time and check for problems like infection or lead issues within 30 days and up to a year. The g…

This study checks for hormone problems in 30 children aged 3-18 with Wilson's disease. Researchers will measure how the disease affects glands like the thyroid and pituitary. The goal is to find and classify these hormone issues to improve care.

This study looks at whether a substance in the blood called uromodulin can help predict how well the kidneys will recover in adults with sepsis-related acute kidney injury. Researchers will measure uromodulin levels at the start of ICU care, after one week, and at discharge. The …

This study compares two ways of cutting the uterus during a planned C-section: using scissors or a scalpel. The goal is to see which method causes less blood loss. The study will include 140 pregnant women between 37 and 42 weeks of pregnancy.

This study looks at how much parents and caregivers know about diaper rash (napkin dermatosis) in children up to 2 years old. Researchers will survey 240 parents at Assiut University Hospital to understand their knowledge, attitudes, and practices. The goal is to find patterns an…

This study will track menstrual cycles in 110 teenage girls (ages 10-18) with and without diabetes to see how diabetes affects period regularity. Researchers will also check if blood sugar control and body weight are linked to menstrual problems. The goal is to better understand …

This study looks at vitamin D levels in 84 adults recently diagnosed with immune thrombocytopenia (ITP), a condition that causes easy bruising and bleeding. Researchers want to see if vitamin D levels are linked to how well patients respond to standard steroid treatment. The goal…

This study looks at how acute kidney injury (AKI) impacts the success and safety of removing breathing tubes in critically ill adults in the ICU. Researchers will track 85 patients to see if AKI makes it harder to wean off mechanical ventilation. The goal is to understand if kidn…

This study looks at how the length of the eye and the strength of a person's glasses prescription relate to the health of the optic nerve and retina. Researchers will use a special camera (OCT) to take detailed pictures of the back of the eye in 266 adults who are nearsighted, fa…

This study will follow 500 people having a major heart attack (STEMI) to see how the time between symptoms starting and getting treatment affects the heart's electrical signals. Researchers will check if longer delays lead to more dangerous heart rhythms or other complications in…

This study looks at how type 2 diabetes changes blood platelets and whether those changes are linked to inflammation. Researchers will compare blood test results from 200 people with diabetes and healthy volunteers. No treatments or extra procedures are involved—just one routine …

This study looks at whether dry eye disease makes it harder to calculate the right lens power before cataract surgery. About 100 adults aged 40 and older who need cataract surgery will take part. Researchers will compare the accuracy of lens power calculations between people with…

This study will follow 125 adults with confirmed stroke to see how factors like symptom awareness, calling an ambulance, and hospital transport affect their recovery. Researchers will use a 20-question test to measure stroke knowledge. The goal is to find gaps in prehospital care…

This study looks at two standard ways of stitching the kidney artery to the iliac artery during a living donor kidney transplant. Researchers will compare interrupted suturing and continuous suturing to see which method shortens cold ischemia time and improves early blood flow. T…

This study uses ultrasound to measure the distance between the Achilles tendon and nearby nerves and blood vessels in babies aged 1-6 months who have clubfoot on one side. By comparing the clubfoot to the normal foot, researchers hope to better understand the anatomy and improve …

This study will track weight and body mass index (BMI) changes in 50 people with inflammatory bowel disease (IBD) who are being treated with biologic drugs. Researchers want to see if weight gain leads to higher drug doses and increased treatment costs. The goal is to understand …

This study will survey 500 non-medical adults in Upper Egypt to learn what they know about H. pylori infection, how it's diagnosed, and what treatments are available. Researchers also want to understand people's attitudes toward testing and treatment, and identify barriers like c…

This study aims to see which method—CT scan, keyhole surgery (laparoscopy), or open surgery—best predicts whether all visible ovarian cancer can be removed. Researchers will enroll 28 women with primary ovarian cancer who are scheduled for surgery. The goal is to improve surgical…

This study looks at a simpler lab test (disk elution) to detect colistin resistance in multi-drug resistant bacteria from 90 hospitalized patients. Researchers will compare it to the standard method and also check for resistance genes. The goal is to make detection easier and fas…

This study watches 160 infants (1-12 months old) with cow's milk protein allergy who are fed a special amino acid-based formula. Researchers will measure weight, length, and head growth over time to see if the formula supports healthy development. No new treatment is given—this i…

This study aims to describe the clinical, blood, and genetic characteristics of 45 adults newly diagnosed with chronic lymphocytic leukemia (CLL). Researchers will examine how specific genetic changes, such as IGHV mutation status and del(17p), relate to how well patients respond…

This study will observe sleep-disordered breathing in 30 adults with systemic sclerosis (scleroderma), a condition that causes skin and organ hardening. Participants will undergo an overnight sleep test to measure breathing pauses. The goal is to better understand how common and …

This study will check if artificial intelligence (AI) can accurately predict how a nose will look after rhinoplasty (nose job) surgery. Researchers will compare AI-generated predictions with actual post-surgery photos using digital analysis. The study involves 20 adults scheduled…

This study will use ultrasound to measure the length and volume of the fetal liver in pregnant women with gestational diabetes. The goal is to see if these measurements can help doctors understand how the mother's blood sugar levels affect the baby. About 115 women will take part…

This study will measure levels of a specific thyroid antibody (anti-thyroglobulin) in 112 adults with diabetes. The goal is to better understand how often diabetes and autoimmune thyroid problems occur together. Participants will give a blood sample, and those with a history of t…

This study will follow 80 newly diagnosed adults with acute myeloid leukemia (AML) to see how their blood clotting changes before and after intensive chemotherapy. The goal is to better understand bleeding risks and improve care. Participants will receive standard treatment and h…

This study looks at why some people with crossed or wandering eyes (strabismus) need a second surgery after their first one. Researchers will track 62 patients who are having repeat surgery to find out which factors make a second operation more likely and how successful the secon…

This study will look at 70 adults who come to Al-Rajhi University Hospital with bright red or maroon blood in their stool. Researchers want to learn the most common causes of this bleeding and how patients fare in the short term. They will also test whether simple checklists can …

This study looks at why children wet the bed (nocturnal enuresis) and what types exist. Researchers will examine 80 children aged 5 and older through interviews, physical exams, and simple tests like urine checks and ultrasounds. The goal is to find underlying medical causes such…

This study looks at whether having a mildly underactive thyroid (subclinical hypothyroidism) changes liver enzymes and cholesterol levels. Researchers will compare 120 adults with and without the condition. No treatments are given—the goal is simply to observe and understand the …

This study will survey 340 female students at Assiut University in Egypt to find out how many have heavy menstrual bleeding and how it affects their daily life, school performance, and iron levels. Participants will answer questionnaires and provide blood samples to check for ane…

This study looks at whether a simple measure called the triglycerides glucose index can help predict small blood vessel problems in people with type 2 diabetes. Researchers will follow 200 adults aged 18 to 65 who have type 2 diabetes. They will check routine lab results to see i…

This study aims to find out how often people with scleroderma have high blood pressure in their lungs (pulmonary hypertension). Researchers will use a heart ultrasound (echocardiography) to screen 35 adults with confirmed scleroderma. The goal is to detect this serious condition …

This study aims to find early warning signs of acute kidney injury in children (ages 1 month to 18 years) admitted to the pediatric intensive care unit. Researchers will track 100 children over one year to see which risk factors—like sepsis, shock, or use of a breathing machine—a…

This observational study will follow 45 adults with severe plaque psoriasis as they receive standard treatment. Researchers will measure changes in skin redness, scaling, and thickness, as well as features seen under a special skin microscope. They will also track how the conditi…

This study will check the 10-year heart disease risk in 238 adults with type 2 diabetes, using a standard WHO risk chart. It will then see if simple belly fat measurements (like waist-based scores) match that risk. No treatment is given—only observation and measurement.

This study looks at how changes in the tiny blood vessels at the back of the eye relate to vision problems in people with multiple sclerosis (MS). Researchers will use a special eye scan (OCT-A) and standard vision tests to find connections. The goal is to better understand MS-re…

This study looks at how heat from climate change affects workers in Upper Egypt. Researchers will teach 84 outdoor workers about staying cool and safe, then check if their health symptoms improve. The goal is to find practical ways to prevent heat-related illness.

This study will look at 300 adults who had an ischemic stroke (a type of stroke caused by a blood clot) to find out how often a large blood vessel in the brain is blocked. Researchers will use CT or MRI scans to check for blockages and track patients' recovery. The goal is to bet…

This study looks at a molecule called PCGEM1 in blood and tissue samples from 90 people newly diagnosed with breast cancer. The goal is to learn more about how breast cancer develops and find possible targets for future treatments. No extra procedures are needed beyond standard c…

This study will check if adding a quick, painless ultrasound measurement of the neck to a standard mouth exam helps doctors better predict when placing a breathing tube during surgery will be difficult. About 160 adults having planned surgery will be randomly assigned to either t…

This study looks at how changes in blood pressure during sleep affect the heart's electrical signals in people with high blood pressure. Researchers will compare those whose blood pressure dips at night to those whose does not. The goal is to better understand heart risks and imp…

This study aims to understand how the size and angle of the eustachian tube (the small passage connecting the middle ear to the throat) relate to pressure inside the middle ear. Researchers will use CT scans to measure these features in 50 healthy volunteers aged 7 and older. The…

This study looks at how common von Willebrand disease is in children in Upper Egypt, what symptoms they have, and how doctors treat it. Researchers will review medical records and check bleeding patterns in up to 25 children aged 0-18. The goal is to help doctors spot and manage …

This study looks at how markers of inflammation (like hs-CRP and neutrophil-to-lymphocyte ratio) and heart damage (troponin) are related to heart function in people with acute coronary syndrome. Researchers will measure these markers and use advanced ultrasound to check heart fun…

This study will track 200 children admitted to the pediatric ICU to see how abnormal levels of minerals like sodium, potassium, and calcium relate to their outcomes. The goal is to find patterns that could help doctors identify risks early and improve treatment. No new treatments…

This study looks at whether a common stomach infection called H. pylori can affect your mood and mental well-being. Researchers will study 130 patients with H. pylori-related gastritis to see how psychological symptoms like anxiety or depression relate to the infection. The goal …

This study looks at whether a scoring tool called BIND can help doctors spot early signs of brain problems in newborns with severe jaundice. Researchers will check 80 babies under 28 days old who need intensive light therapy. The goal is to see if the score can predict which babi…

This study looks at how well ultrasound can find and describe fluid buildup in the belly (ascites) and figure out what's causing it. About 125 people with suspected ascites will get an abdominal ultrasound. The goal is to see how accurate ultrasound is for this purpose, which cou…

This study will check how common depression, anxiety, and burnout are among heart disease patients and the healthcare workers who treat them at Assiut University Heart Hospital. About 380 people will fill out questionnaires to measure their mental health. The goal is to understan…

This study will watch and record information from 120 newborns admitted to the NICU with serious stomach or gut problems. The goal is to learn which emergencies are most common and what factors lead to better or worse outcomes. No new treatments are tested; the study only collect…

This study will look at 35 children aged 1 to 18 with acquired aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. Researchers will record their symptoms, possible causes, and how they are treated. The goal is to better understand the disease …

This study follows 120 adults who had a stroke and a procedure to remove a blood clot from a large brain artery. Researchers want to find out why some people develop problems with memory, attention, or thinking afterward. Participants will take thinking tests and mood surveys at …

This study looks at whether measuring a substance in the blood called lipoprotein(a) can help predict future heart problems in people who have had a stent placed to open a blocked artery. About 156 adults with stable heart disease will have their blood tested before the procedure…

This study looks at 100 men with varicoceles (enlarged veins in the scrotum) to see if the amount of backward blood flow affects sperm health. Participants will have ultrasound and semen tests before and 3 months after surgery. The goal is to learn which patients benefit most fro…

This study will check if having an H. pylori stomach infection is linked to how active lupus (SLE) is in 115 adults. Participants will answer questions, have a stool test for H. pylori, and get their lupus activity scored. No treatment is given—the goal is simply to learn more ab…

This study looks at whether a non-invasive device called ICON® can reliably measure heart function in people with COPD who are in the intensive care unit. Researchers will check if the device's readings are useful for guiding treatment and detecting changes caused by breathing ma…

This study looks at whether ultrasound measurements of the femoral or jugular vein collapse can help doctors assess fluid loss in trauma patients with shock, compared to the standard inferior vena cava measurement. About 50 adults with hypovolemic shock will be scanned before and…

This study will look at 160 very premature babies (born before 32 weeks and weighing under 1,500 grams) to find out why some of them fail non-invasive breathing support like CPAP and need a breathing tube instead. Researchers will review medical records from a children's hospital…

This study looks at how the thyroid and adrenal glands work in 200 ICU patients with septic shock, a life-threatening infection that causes organ failure. Researchers will measure hormone levels in the blood to see if gland problems are common. No treatment is given—the goal is s…

This study will look at medical records from 50 adults with glioblastoma, a fast-growing brain tumor. Researchers want to see how much of the tumor is removed during surgery and how that, along with standard chemotherapy and radiation, affects how long patients live. The goal is …

This study will look at why some newborns in the intensive care unit develop anemia (low red blood cells) and how it affects their recovery. Researchers will track 40 babies to find risk factors like infections or birth complications. The goal is to better understand the problem …

This study will look at blood test results from 100 adults with myelodysplastic syndromes (MDS) to see if certain markers can predict how the disease will progress. Researchers will check levels of hemoglobin, albumin, lymphocytes, platelets, and other factors. The goal is to bet…

This study will check how often an enlarged spleen occurs in 100 adults with low platelet counts caused by various blood disorders. Researchers will compare symptoms, complications, and treatment responses between those with and without an enlarged spleen. The goal is to better u…

This study looks at body composition—fat, muscle, and bone mass—in children aged 5 to 18 with beta thalassemia major who receive regular blood transfusions. Researchers will use a simple test called bioelectrical impedance to measure these factors and see how they relate to trans…

This study looks at 32 children with a first episode of ADEM, a rare brain and spinal cord inflammation that often follows a virus. Researchers will check early MRI scans and spinal fluid samples to see if they can predict which children will recover fully and which might have la…

This study looks at whether adding a T2 mapping scan to a regular knee MRI can help doctors find early signs of osteoarthritis. Researchers will compare MRI results from 28 healthy people and 28 people with early knee arthritis. The goal is to see if this extra scan makes it easi…

This study looks at whether a short classroom program can help teenagers in Assiut, Egypt, learn more about mental health, feel less stigma, and be more willing to seek help. About 150 students aged 13-18 will take part, with half receiving the program and half not. Researchers w…

This study will check 138 children with congenital heart disease for chromosomal abnormalities using a blood test. Researchers want to find out how often these genetic issues occur and how they relate to specific heart problems. The goal is to improve diagnosis, treatment, and fa…

This study will check if certain substances in the blood, like surfactant protein-D and other markers of inflammation, can help doctors predict how severe a COPD flare-up will be in patients who need hospital care. Researchers will measure these markers in 75 adults with COPD and…

This study compares two scoring systems (REDS and qSOFA) to see which better predicts death within 30 days in emergency patients with suspected sepsis. Researchers will enroll 80 adults at Assiut University. The goal is to improve early identification of high-risk patients and po…

This study will follow 30 children under 18 who have surgery for a specific type of brain tumor (midline posterior fossa). Researchers want to see how well children recover after surgery and what factors affect their recovery and survival. The goal is to learn more so doctors can…

This study looks at adults with intussusception, a condition where part of the intestine slides into another part, causing a blockage. Researchers want to find out how often the cause is harmless (like a benign growth) versus cancer. They will also check how well CT scans predict…

This study will check how tyrosine kinase inhibitors (TKIs), the main drugs for chronic myeloid leukemia (CML), affect blood sugar and cholesterol levels. Researchers will measure changes in HbA1c (a blood sugar marker) and lipid profile (cholesterol and fats) in 75 CML patients.…

This study looks at whether a simple blood test score, called the CALLY index, can help predict short-term problems in people having emergency angioplasty after a major heart attack. Researchers will follow 140 patients for 30 days to see if the score is linked to complications l…

This study compares two surgical methods for treating early-stage endometrial cancer: laparoscopy (keyhole surgery) and laparotomy (open surgery). It aims to see which approach is safer and more effective in hospitals with limited resources. About 116 participants will be enrolle…

This study watches 120 critically ill adults in the ICU to see if the amount of fluids they get in the first 48 hours is linked to acute kidney injury (AKI). Participants must not have kidney injury at the start. Doctors will track fluids, weights, and lab tests to see who develo…

This study compares two ways of using a breathing machine during laparoscopic abdominal cancer surgery. It looks at how each method affects the heart and lungs. The trial involves 60 adults aged 20-80 who are scheduled for this type of surgery.

This study looks at whether a common laser treatment for advanced diabetic eye disease (called panretinal photocoagulation) affects the cells that keep the front of the eye clear. Researchers will measure these cells before and after treatment in 45 patients. The goal is to under…

This study compares two types of knee X-rays (full-leg standing and Rosenberg view) to see if they give different measurements of the knee angle in people undergoing high tibial osteotomy. About 49 patients with knee arthritis will be included. The goal is to find out which X-ray…

This study looks at how intestinal parasites might make malnutrition worse in children aged 2 to 15 in Assiut, Egypt. Researchers will compare 116 malnourished children with healthy ones to see how common these infections are. The goal is to better understand the link between par…

This study will follow 60 children aged 1 month to 18 years who have supraventricular tachycardia (SVT), a condition where the heart suddenly beats very fast. Researchers want to see how these children do over time, what treatments work best, and how often the fast heartbeats com…

This study looks at whether the time between first symptoms of an anal fistula and surgery changes how well patients heal. Researchers will follow 90 adults who need surgery, grouping them by how long they had symptoms (3 months or less, 3-6 months, or more than 6 months). The go…

This study will look at the medical history, lab results, and treatments of 30 people with Behçet's disease at a hospital in Upper Egypt. The goal is to better understand which symptoms are most common and how the disease is managed in this region. Participants must have a confir…

This study will check how often babies under two years old with cholestasis (a liver problem) also have congenital heart defects. It will also look at their physical and mental development. The goal is to better understand the link between these conditions, but no treatment is gi…

This study looks at how the bacteria in your gut might influence heart recovery after a heart attack procedure called primary PCI. Researchers will measure a substance called TMAO, made by gut bacteria, in 144 adults before and after the procedure. The goal is to understand if gu…

This study looks at the health, nutrition, and daily living abilities of adults aged 60 and older living in a rural village in Assiut, Egypt. Researchers will interview participants and do simple physical checks to understand common health problems and risks. No treatments are gi…

This study looks at whether ultrasound can accurately detect when bone has healed enough during Ilizarov frame treatment. Researchers will compare ultrasound images with standard X-rays and physical exams in 56 patients. If successful, ultrasound could provide a safer, radiation-…

This study will track 300 premature babies (born before 34 weeks and weighing under 1500 grams) to see how often they develop bleeding in the brain. Researchers will look for factors that raise the risk and monitor short-term outcomes like survival, seizures, and need for surgery…

This study looks at children ages 1 month to 5 years with pneumonia to find out which signs and tests best predict severe illness. Researchers will check vital signs, lab results, and X-rays to see which children need oxygen, ICU care, or have complications. The goal is to help d…

This study will observe 55 adults with obstructive sleep apnea to see if the severity of their breathing pauses during sleep is linked to higher blood pressure in the lungs. Participants will have their sleep and heart function measured, but no new treatments are tested. The goal…

This study looks at whether having a baby soon after a previous C-section increases the chance of problems like heavy bleeding or organ injury during the next C-section. Researchers will follow 80 pregnant women with one prior C-section. The goal is to help women and doctors plan…

This study will check how certain leukemia drugs (called tyrosine kinase inhibitors) affect the thyroid gland in people with chronic myeloid leukemia. Researchers will measure thyroid hormone levels in 76 newly diagnosed adults over time. The goal is to learn how often thyroid pr…

This study looks at whether a protein called IL-33 in the blood is linked to lupus symptoms, especially kidney problems. Researchers will compare IL-33 levels in 150 adults: lupus patients with kidney disease, lupus patients without kidney disease, and healthy people. The goal is…

This study will look at 70 children aged 1 month to 18 years who come to the emergency room with severe breathing trouble. Researchers want to find out how common this is, what causes it, and which children are most at risk. The goal is to better understand and manage this seriou…

This study compares two ways to remove the uterus for non-cancerous reasons: laparoscopic (keyhole) surgery and open abdominal surgery. The goal is to see which leads to a shorter hospital stay in settings with limited resources. The study will include 32 women aged 35-65 who nee…

This study looks at how a class of diabetes medicines called SGLT2 inhibitors may change the size and function of the heart's left atrium in people with type 2 diabetes. Researchers will use ultrasound to measure heart changes before and after 6 months of treatment. The study inv…

This study looks at why some children are born with a droopy eyelid (congenital ptosis). Researchers will examine the eyelid muscle during surgery and under a microscope to understand its development. The goal is to learn more about the condition, not to test a new treatment. Abo…

This study looks at children with chronic abdominal pain (lasting 3 months or more) to see how often an upper endoscopy—a camera test that looks inside the stomach—finds a medical cause. About 130 children aged 18 or younger will be included. The goal is to help doctors decide wh…

This study explores whether frailty can help predict bleeding risk in older adults (65+) who have had a heart attack or unstable angina. Researchers will follow 850 participants for up to 6 months to see if adding frailty to standard risk tools improves predictions. The goal is t…

This study will measure two immune proteins, IL-17A and IL-10, in the blood of 80 newly diagnosed adults with B-cell acute lymphoblastic leukemia (B-ALL) in South Egypt. Researchers want to see if these protein levels are linked to lab results and how well patients respond to tre…

This study looks at the types of bacteria causing deep neck infections in 50 adults. Researchers will compare lab results with how patients recover, including hospital stay length and complications. The goal is to find better ways to diagnose and treat these serious infections by…

This study looks at children under 18 with chronic liver disease to see if they have hidden heart problems. Doctors will use simple tests like blood work, ultrasound, and heart scans to check for conditions such as portopulmonary hypertension and cirrhotic cardiomyopathy. The goa…

This study will check how common electrolyte disturbances (like low sodium or potassium) are in infants and children aged 1 month to 4 years who are hospitalized with gastrointestinal diseases. Researchers will measure electrolyte levels in 150 children to find out which types of…

This study will look at 80 cancer patients getting PET/CT scans to see if different ways of measuring the scan results are more accurate. The goal is to find the best method, especially for patients who are obese. This is an observational study that does not involve any treatment…

This study looks at how frailty—a state of reduced strength and health—impacts treatment choices and short-term results in people aged 65 and older who have had a heart attack. Researchers will follow 645 participants for 30 days to see if adding frailty checks to standard risk s…

This study looks at how different risk factors, like iron overload from blood transfusions, affect the growth of children with beta-thalassemia major. Researchers will measure height, weight, and body mass index in 85 children aged 1 to 18. The goal is to better understand growth…

This study looks at whether low iron levels (with or without anemia) raise the risk of heart rhythm problems in people hospitalized for heart failure. Researchers will check 300 adults for iron deficiency and monitor their heart activity using ECGs. The goal is to find simple way…

This study will enroll 70 pregnant women to test a new ultrasound scoring system that combines standard amniotic fluid measurements with fetal bladder size and appearance. The goal is to see if this combined method can more accurately detect too little or too much amniotic fluid.…

This study looks at two blood markers (MMP7 and MMP9) to see if they can help detect lung disease in people with rheumatoid arthritis. Researchers will compare three groups: RA patients with lung disease, RA patients without lung disease, and healthy volunteers. The goal is to fi…

This study looks at how often tendon inflammation (tenosynovitis) occurs in children with two types of juvenile idiopathic arthritis. Researchers will use ultrasound, a safe imaging tool, to detect inflammation that might be missed during a regular physical exam. The goal is to i…

This study looks at the real-life challenges faced by people with Wilson's disease in Upper Egypt, a rare condition where copper builds up in the body. Researchers will survey 66 patients about their diet, mental health, and access to care, and create a map showing where patients…

This study examines tissue samples from 50 women with type 1 endometrial cancer to measure levels of a protein called METTL-14. Researchers want to see if higher or lower amounts of this protein are linked to tumor features and patient survival. The goal is to better understand w…

This study looks at 72 adults with rheumatoid arthritis to see if certain blood markers and ultrasound images can better track disease activity. Researchers will compare patients taking JAK inhibitors with those on standard treatments. The goal is to find simpler, more accurate w…

This study looks at how obesity and gastroesophageal reflux disease (GERD) are connected. Researchers will measure how common obesity is among 200 adults with GERD. The goal is to better understand the link between these two conditions.

This study will look at 80 children with Guillain-Barré syndrome to find out which factors help predict a full recovery within 3 months. Researchers will track symptoms and test results to build better prediction tools. The goal is to improve treatment and care for young patients…

This study will check 200 adults with fatty liver disease for high uric acid levels, a condition called hyperuricemia. Researchers want to find out how common it is and how it relates to liver health. The goal is to better manage fatty liver disease and improve patients' well-bei…

This study compares two types of temporary stomas—loop ileostomy and loop transverse colostomy—used after colorectal surgery to protect the healing bowel. About 36 adults who need a diverting stoma will take part. The goal is to see which stoma leads to fewer complications like l…

This study looks at whether people with substance use disorder have more obsessive-compulsive symptoms than those without. Researchers will compare 102 adults (ages 18-50) who are in recovery from addiction with a similar group of healthy volunteers. Participants will complete in…

This study looks at how well doctors follow infection prevention steps before, during, and after C-sections. It will track 105 women for 30 days after surgery to see how many get an infection. The goal is to find out if following the rules helps reduce infections and improve reco…

This study looks at how common lactose intolerance is in people with chronic diarrhea caused by irritable bowel syndrome (IBS-D). Researchers will test 70 participants using a PCR test and a symptom questionnaire. The goal is to better understand the link between lactose intolera…

This study aims to see if certain blood test results related to platelets (small cells that help blood clot) can show how active inflammatory bowel disease (IBD) is. Researchers will measure platelet levels and compare them to standard disease activity scores in 84 adults with IB…

This study examines tissue samples from 100 bladder cancer patients to see if two microscopic features—how deep early tumors invade and small cell clusters at the tumor edge—can predict cancer return, spread, or survival. Researchers will review past medical records and lab slide…

This study will look at how often bronchoscopy successfully removes objects that children may have inhaled. Researchers will also track any problems that happen within 24 hours, like low oxygen or bleeding. The study includes children under 18 with a suspected inhaled object, but…

This study aims to improve how doctors estimate a baby's weight before birth by also measuring soft tissue thickness, not just bone size. About 300 pregnant women at 37 weeks or more will have an ultrasound within 72 hours of delivery. The goal is to create a more accurate formul…

This study will enroll 80 adults in the emergency department who are in shock from blood loss, infection, or bleeding. Researchers will compare two ways to detect low blood volume: an ultrasound of the inferior vena cava (a large vein) versus a standard pressure monitoring cathet…

This study will check if a new scoring system called STARZ can predict kidney injury in newborns within the first week of life. Researchers will enroll 140 babies in the NICU and compare the STARZ score to standard tests. The goal is to catch kidney problems early so doctors can …

This study looks at whether teenagers aged 15-19 in Beni Adi village, Egypt, have their rights fulfilled in health, education, protection, and community involvement. Researchers will interview 300 teens to check things like school attendance, access to healthcare, and safety from…

This study will test three heart failure risk models (MAGGIC, GWTG-HF, and SHFM) in 140 Egyptian patients to see how well they predict death and hospital readmission. These models were created using mostly Western patients, so they may not be accurate for Egyptians, who tend to b…

This study looks at whether anemia (low red blood cells) can help predict how Inflammatory Bowel Disease (IBD) will progress in patients. Researchers will track 83 adults with IBD at Assiut University Hospitals to see if those with anemia have higher hospitalization rates. The go…

This study looks at how heart procedures affect the mental health of people with congenital heart disease. Researchers will follow 60 patients before and after surgery or catheter treatment, checking for depression, anxiety, and other psychiatric symptoms. The goal is to better u…

This study looks at 100 people with microbial keratitis, a serious eye infection, at Assiut University Hospital in Egypt. Researchers will collect information on risk factors, germs causing the infection, complications, and how patients recover. The goal is to better understand t…

This study will check how often people have trouble with memory, attention, and other thinking skills after a stroke. Researchers will evaluate 400 adults aged 18 to 60 who had their first stroke within the last 3 months. The goal is to understand how common these problems are, n…

This study looks at whether a common stomach infection called H. pylori is more common in women who have had two or more miscarriages without a known cause. Researchers will compare 100 women with unexplained recurrent miscarriages to see if those with H. pylori infection have a …

This study will compare MRI scans to standard X-rays for evaluating knee joint damage in adults with hemophilia who have had repeated bleeding in the knee. The goal is to see if MRI can better detect early changes in the joint lining, cartilage, and bone. Results may help doctors…

This study will compare two noninvasive methods—electrical cardiometry and echocardiography—for measuring how well the heart pumps blood in people with septic shock. Researchers want to see if the simpler electrical method can be a reliable alternative to ultrasound. The study wi…

This study looks at 100 adults with advanced chronic kidney disease who also have fluid buildup around their lungs. The goal is to find out what causes this fluid and which lab test is most accurate for these patients. By comparing chest fluid and blood samples, researchers hope …

This study will look at how often children with sickle cell disease have painful vaso-occlusive crises and what problems arise from them. Researchers will review medical records of 25 children aged 1-18 to find risk factors and complications like acute chest syndrome or stroke. T…

This study will check how common epiretinal membrane (a thin scar-like layer on the retina) is in people with diabetic retinopathy. Researchers will look at 225 adults to find possible risk factors like age, diabetes control, and other health conditions. No treatments are tested—…

This study looks at whether a substance in the blood called catestatin can help doctors understand how active systemic sclerosis (a rare autoimmune disease) is, especially when it affects the heart and small blood vessels. Researchers will compare catestatin levels in 70 people w…

This study compares two medications, dexmedetomidine and magnesium sulfate, to see which better controls pressure inside the skull during brain surgery. Sixty adults having elective craniotomy will receive one of the drugs, and their brain pressure will be continuously measured u…

This study looks at the link between high uric acid levels (hyperuricemia) and fatty liver disease in 111 obese adults. Researchers want to see if high uric acid increases the risk of liver scarring (fibrosis). The goal is to find ways to catch liver problems early and possibly u…

This study will survey 420 pregnant women in their third trimester in Assiut, Egypt, to understand their knowledge, attitudes, and practices regarding self-medication. Researchers will use a questionnaire to find out what medications women take on their own, why, and where they g…

This study will check if people with abnormal blood vessels in the gut (angiodysplasia) also have blood disorders like von Willebrand disease. Researchers will test 55 adults using endoscopy, colonoscopy, and blood work. The goal is to see if a blood marker called von Willebrand …

This study looks at heart health in 70 children (1 month to 18 years) who have brain conditions like seizures, migraine, or encephalopathy. Researchers will use echocardiograms and ECGs to find hidden heart problems such as arrhythmias or structural defects. The goal is to unders…

This study looks at whether a combination of common blood test results (hs-CRP, triglycerides, and glucose) can help detect liver fibrosis in people with non-alcoholic fatty liver disease (NAFLD). Researchers will observe 96 adults who have NAFLD and compare their blood markers t…

This study looks at how long-acting reversible contraception (LARC) affects women's quality of life. Researchers will compare women using LARC methods (like IUDs or implants) with those using other birth control. About 427 women aged 18-45 will complete a questionnaire about thei…

This study will track 50 children under 15 with a specific elbow fracture to see how often blood vessel injuries occur and what treatments work best. Researchers want to find risk factors that lead to these complications. The goal is to improve care and outcomes for these young p…

This study looks at 200 adults with a type of fatty liver disease called MASLD. The goal is to find out how many of them are also obese, and to learn more about those who are not obese but still have the disease. Researchers will use medical exams, lab tests, and imaging to gathe…

This study surveys 300 general practitioners in Upper Egypt to find out what they know about diagnosing and treating H. pylori, a common stomach infection. The goal is to identify gaps in knowledge and barriers that prevent proper care. No treatments are given; the study only col…

This study looks at whether the ratio of two substances in the blood (CRP and albumin) can help doctors predict acute kidney injury in people with acute pancreatitis. Researchers will follow 150 adults with pancreatitis to see if this simple, low-cost test can spot kidney problem…

This study looks at how children with a large hole in the heart (VSD) grow after surgery to close it. Researchers will measure weight, height, and BMI before and after the procedure in 58 children aged 1 month to 2 years. The goal is to see if and when they reach normal growth le…

This study looks at how congenital heart disease (CHD) affects growth in children aged 1 month to 2 years. Researchers will review medical records of 72 children to compare their weight, height, and head circumference with healthy growth standards. The goal is to understand which…

This study will look back at medical records of 100 people with newly diagnosed epilepsy to see if the number of seizures they have at the start can predict how well their seizures are controlled in the long run. Researchers will also consider early response to medication and oth…

This study will check 230 children with Down syndrome and their parents to see how many have a rare inherited form called translocation Down syndrome. The goal is to better understand how often this type occurs and help families know the chances of having another child with the c…

This study will follow 82 children with asthma, aged 6 to 12, to see how other health problems (comorbidities) and specific substances in the blood (called biomarkers) influence how well they respond to treatment. Researchers will measure lung function and look at levels of certa…

This study looks at the challenges women survivors of gender-based violence face when seeking healthcare in Upper Egypt. Researchers will interview healthcare providers and survivors to identify key barriers and opportunities. The goal is to develop recommendations to make Women'…

This study aims to find the smallest follicle size that still leads to successful egg retrieval during IVF/ICSI. Researchers will measure follicle number and size via ultrasound in 60 women aged 18-35, then compare those measurements to the number of eggs actually retrieved. The …

This study will test if a detailed heart ultrasound (speckle tracking echocardiography) can find early signs of heart trouble in 100 adults with inflammatory bowel disease (IBD). Researchers want to see if this method is better than standard tests at linking gut disease activity …

This study will enroll 59 women with suspicious or confirmed breast masses to see if MRI-based 3D volume measurements match the actual tumor size found during surgery. Accurate tumor sizing helps doctors plan better surgeries and chemotherapy. Participants will have a contrast-en…

This study will look at genetic test results from 75 children aged 1 month to 12 years who have birth defects and developmental delays. Researchers will collect medical history, do physical exams, and review chromosome tests to find the types of genetic problems causing these con…

This study looks at 95 adults with complicated lung infections (parapneumonic effusion) who need surgery. Doctors want to see if a simple score (RAPID) and ultrasound pictures can predict which type of video-assisted surgery (VATS) is needed—either cleaning or a more extensive pr…

This study will survey about 289 medical students and interns at Assiut University to find out how many experience anxiety or depression. Researchers will use standard questionnaires and look for links to academic performance and other risk factors. The goal is to better understa…

This study will check if two routine blood test values (mean platelet volume and platelet distribution width) can serve as early warning signs for deep vein thrombosis in 100 adults who are on breathing machines in the ICU. Participants will be monitored with Doppler ultrasound t…

This study looks at how alienation—feeling disconnected or estranged—affects the mental health, social life, and overall quality of life of medical students at Assiut University. Researchers will survey 77 international or non-local students using a standard quality-of-life quest…

This study will use ultrasound to look for hidden joint inflammation in people with inflammatory bowel disease (IBD) who have no known joint problems. Up to half of IBD patients may have joint issues that go unnoticed. The goal is to create a standard ultrasound method to catch t…

This study aims to see if certain markers of inflammation in the blood can help detect kidney damage early in people with type 2 diabetes. Researchers will measure these markers in 80 adults and compare them to a known marker called MCP-1. The goal is to find simpler ways to iden…

This study looks at 70 children and teens with juvenile lupus to see if they have early signs of heart disease. Researchers will use ultrasound to measure the thickness of the carotid artery wall and compare it to healthy children. The goal is to understand how lupus and its trea…

This study tests whether a bedside lung ultrasound can help doctors see how well collapsed lung areas reopen in obese patients on breathing machines. About 45 adults with a BMI of 33 or higher will be scanned before, during, and after a standard lung-opening procedure. The goal i…

This study looks at 80 samples of a tough bacterium called Pseudomonas aeruginosa that are resistant to many drugs. Researchers will measure the activity of a specific gene (mexB) and check how well the bacteria form protective slime layers (biofilms). The goal is to understand t…

This study looks at how being overweight or obese might change how well treatments work for people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 120 adults with IBD who are on standard therapies, including biologi…

This study will check if people with lupus nephritis (kidney inflammation caused by lupus) have low zinc levels. Researchers will measure zinc in the blood and see if it relates to kidney function tests like creatinine and eGFR. The goal is to understand the connection, not to te…

This study aims to find out how often children with epilepsy also have symptoms of ADHD. Researchers will look at possible risk factors and how ADHD symptoms affect the child's epilepsy. The study will include 185 children over age 3 who have epilepsy and are seen at Assiut Unive…

This study looks at why some people who need regular blood transfusions develop harmful antibodies against donor blood. Researchers will measure a small molecule called microRNA-155 in 100 transfusion-dependent patients to see if it is linked to this immune reaction. The goal is …

This study will test whether a special MRI scan can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The scan is non-invasive and may be more accurate than current methods. Researchers will enroll 40 adults with chronic thyroid disease who…

This study looks at two immune receptors, CD85d and CD305, in people with B-cell blood cancers. Researchers want to see how these receptors are expressed in different cancer types and if they can help predict how the disease will progress. The goal is to better understand these c…

This study looks at how common muscle loss (sarcopenia) is in people with inflammatory bowel disease (IBD) using CT scans. Researchers want to see if muscle loss affects how well biologic treatments work. About 50 adults with IBD who are on biologic therapy will be included.

This lab study uses bacteria from 60 people with urinary tract infections to see if chitosan nanoparticles (made from shrimp shells) can destroy the sticky biofilms that make infections hard to treat. Researchers will test the nanoparticles alone and with the antibiotic ciproflox…

This study aims to understand the relationship between metabolic syndrome (a cluster of conditions like high blood pressure and excess body fat) and gastroesophageal reflux disease (GERD), commonly known as acid reflux. Researchers will observe 50 adult patients with metabolic sy…

This study aims to understand how severe bloodstream infections (sepsis) damage children's hearts. Researchers will observe 84 critically ill children with sepsis to identify early signs of heart injury and track their recovery. The goal is to help doctors better predict and mana…

This study aims to find a better blood test to detect active kidney inflammation in people with lupus nephritis. Researchers will measure a specific antibody in the blood of 96 participants and compare it to results from kidney biopsies. The goal is to develop a less invasive way…

This study aims to understand how two specific proteins, CD274 and CD276, are present in different types of B-cell cancers. Researchers will analyze blood and bone marrow samples from 159 newly diagnosed patients using a lab technique called flow cytometry. The goal is to gather …