Assiut University

This study aims to see if a new topical gel containing dutasteride works as well as or better than a standard triple-combination acne gel. Researchers will compare how well each treatment reduces acne lesions and improves skin appearance over 12 weeks in 50 adults with facial acn…

This study is testing a specific surgical method to cover large or deep wounds on the lower leg, ankle, or foot. Doctors will move a flap of skin and tissue from the outer calf to cover the wound, aiming to improve healing. The trial will enroll 30 adult patients to see how well …

This study aims to see if using surgical scissors instead of a scalpel to make the initial cut in the uterus during a planned C-section leads to less blood loss for the mother. It will involve 140 pregnant women aged 18-40 having an elective C-section. The goal is to find a safer…

This early-stage study aims to see if a cream containing ivermectin, a drug used for other skin conditions, can help clear common warts. Researchers will compare the cream used alone, the cream applied after a microneedling procedure, and a standard salicylic acid treatment. Abou…

This study aims to test the safety and effectiveness of a medication called romiplostim in children with chronic immune thrombocytopenia (ITP), a condition where the body attacks its own platelets. It will involve 100 children aged 1-18 who have not responded well to standard fir…

This study compares two different treatment schedules for children who have taken too much paracetamol (acetaminophen). Researchers want to see if a shorter 12-hour treatment works as well as the standard 21-hour treatment at preventing liver damage. The study will enroll 102 chi…

This study is testing a new topical cream containing apremilast nanoparticles for people with mild to moderate plaque psoriasis. It will compare the new cream against a standard steroid cream and a combination of both. The goal is to see if the new cream can effectively treat pso…

This study aims to see if a minimally invasive throat procedure called POEM works equally well for people with a swallowing disorder called achalasia, whether it's their first treatment or if they've had a prior dilation treatment that didn't last. Researchers will compare two gr…

This study aims to see if a structured, supervised exercise program (cardiac rehabilitation) helps the heart muscle recover and prevents long-term damage in people who have had a major heart attack treated with a stent. Researchers will enroll 100 stable patients and randomly ass…

This study tests a shorter radiation schedule for early vocal cord cancer. Researchers want to see if giving higher radiation doses over fewer visits works as well as traditional longer treatments. The goal is to control the cancer while preserving patients' voice quality and red…

This study aims to find out if a thinner slice of ear cartilage works better than a thicker piece for patching holes in the eardrum. It will involve 30 adults with long-standing eardrum perforations. Researchers will compare how well each graft heals and whether it affects hearin…

This study is testing a more intensive schedule of two chemotherapy drugs (gemcitabine and cisplatin) given before surgery to remove the bladder. The goal is to see if this approach is safe and effective at shrinking tumors in patients with muscle-invasive bladder cancer. Researc…

This study aims to see if children with a hip development problem (DDH) can safely wear a full-leg cast for 6 weeks instead of the usual 12 weeks after corrective surgery. It will compare the hip's stability and healing, as well as complications like skin sores, between the two g…

This study compares two different ways to drain fluid after heart bypass surgery. Researchers want to see which method better prevents irregular heartbeats and fluid buildup around the heart. The trial will involve 122 patients having their first elective bypass surgery. Results …

This study is testing whether injections of platelet-rich plasma (PRP), made from a person's own blood, can help improve voice quality for people with certain vocal fold problems like scarring, grooves, or thinning. Researchers will enroll 48 participants to see if PRP injections…

This study aims to understand the best ways to treat children with supraventricular tachycardia (SVT), a condition causing a very fast heartbeat. Researchers will follow 60 children at a hospital in Egypt to see which immediate and long-term treatments work best and how often the…

This study aims to understand how caffeine therapy affects the heart and blood pressure of premature babies being treated for breathing pauses. It will closely monitor 40 preterm infants in a neonatal intensive care unit who are already receiving standard caffeine treatment. Rese…

This study is testing a new, step-by-step emergency plan called the MINUTES bundle. It's designed to help doctors quickly stabilize adults who arrive at the ER with life-threatening shock when the cause is unknown. The goal is to see if following this specific 30-minute checklist…

This study compares two types of cages used in a common neck surgery for worn-out spinal discs. Researchers want to see if a newer cage design with built-in screws provides better stability and bone healing than the traditional cage. They will follow 40 patients for one year, mea…

This study aims to find the best surgical approach for infants born with blocked nasal passages (choanal atresia). Researchers will compare two different endoscopic techniques to see which one keeps the airway open longer with fewer complications. The study will include 30 childr…

This study compares two similar surgical procedures for people with severe excessive sweating. Researchers want to see if operating on one nerve level versus two nerve levels results in fewer patients developing a common side effect where they start sweating heavily in new body a…

This study is testing if a stronger stitching method for repairing cut finger tendons allows patients to start moving their hand sooner without needing a protective splint. Doctors will perform the surgery using only local anesthesia while the patient is awake, then have patients…

This study looks at two standard ways surgeons stitch the new kidney's artery to a patient's blood vessel during a living donor transplant. It will compare the interrupted stitch method to the continuous stitch method in 70 adult patients. The main goal is to see if one method le…

This study aims to see if placing children on their side or semi-stomach after tonsil and adenoid surgery helps them breathe better as they wake from anesthesia. It will compare these positions to lying flat on the back, which carries a higher risk of low oxygen levels. The goal …

This study is testing whether combining an oral medication (tranexamic acid) with a skin treatment (glutathione-assisted microneedling) works better than either treatment alone for reducing melasma. Melasma causes dark, patchy discoloration on the face, often in women. Researcher…

This study is testing a new approach called 'woundsome revascularization' to improve blood flow directly to foot wounds in patients with severe limb-threatening ischemia. Researchers want to see if this targeted approach helps prevent leg amputations and promotes wound healing be…

This study is testing a new surgical technique called Active Apex Correction (APC) for young children with progressive, severe scoliosis. The goal is to correct the spinal curve and control its worsening while still allowing the child's spine to grow normally, potentially avoidin…

This study aims to see if giving vitamin D supplements helps critically ill children with serious breathing problems. It will measure if the vitamin helps them leave the hospital sooner and spend fewer days on a breathing machine. The trial will include 40 children aged 1 month t…

This study is testing whether using a larger volume of fluid during a specific injection treatment works better for carpal tunnel syndrome. Researchers will enroll 35 adults with mild-to-moderate carpal tunnel to see if bigger injections provide more pain relief and better functi…

This study is testing a combined surgical technique for complex hip fractures where the outer bone wall is weak. Doctors will use both a rod inside the bone and a plate on the outside to see if this provides better stability and prevents the bone from collapsing or shifting out o…

This study compares two medications—dexmedetomidine and magnesium sulfate—to see which better controls brain pressure and blood flow during brain surgery. Researchers will monitor 60 adult patients having elective brain surgery using a special drain to measure pressure directly. …

This study is testing if a sodium bicarbonate enema can help adults with chronic kidney disease (CKD). The goal is to see if it can relieve constipation and reduce the buildup of harmful waste products in the body. Researchers will measure toxin levels in the blood before and aft…

This study is testing whether a radioactive iodine treatment can help control thyroid cancer in a specific situation. It's for adults who have had surgery and initial treatment, but now have high blood markers suggesting the cancer might be active, even though their follow-up sca…

This study aims to see if giving magnesium sulfate through an IV within 24 hours of a traumatic brain bleed can prevent or reduce dangerous artery spasms in the brain. It will involve 50 adults who have suffered this specific type of head injury. The goal is to see if this early …

This study is testing whether injecting platelet-rich plasma (PRP) into surgical wounds can help them heal faster after anal fistula surgery. Researchers will compare 70 patients who receive PRP injections with those who don't, measuring how quickly wounds close and how much pain…

This study is testing whether a cream containing the antifungal medicine terbinafine can effectively treat fungal ear infections (otomycosis). About 50 adults in Egypt with a confirmed infection will have a medicated ear pack placed in their ear canal, which will be changed every…

This study aims to find out which of two common temporary bowel openings is better at preventing and managing a serious leak after colorectal surgery. It will compare a loop ileostomy (small intestine opening) with a loop transverse colostomy (large intestine opening) in 36 adult…

This study aims to find the best way to give a common type of antibiotic to adults with severe infections (sepsis) in the intensive care unit. It will compare giving the medicine in longer, extended infusions versus the standard shorter, intermittent doses. The goal is to see whi…

This study looks at the long-term results of a complex surgery for children who lost part of their hip bone due to a severe joint infection. Doctors take a growth plate and bone from the patient's lower leg and transplant it to the damaged hip, aiming to restore growth and functi…

This study compares two common treatments for small kidney stones located in the lower part of the kidney. Researchers want to see whether minimally invasive laser surgery (fURS) or external shock wave therapy (ESWL) works better to completely remove stones. The study will involv…

This study is testing two types of minimally invasive heat treatments for masses in the abdominal wall. It aims to see if using needles to deliver heat (radiofrequency or microwave energy) can effectively destroy these tumors and control their growth. The goal is to provide an op…

This study is testing if starting a specific type of physical therapy very soon after a stroke helps people recover better. It compares 'task-oriented' therapy, which focuses on practicing everyday activities like walking or buttoning a shirt, to standard physical therapy. About …

This study is testing a surgery that cuts and shifts the heel bone to relieve tension on a painful foot tendon, aiming to reduce pain without cutting the tendon itself. It is for adults with long-term plantar fasciitis (heel pain) that hasn't gotten better with at least 6 months …

This study aims to see if six months of treatment with the heart failure drug sacubitril/valsartan improves how well the heart relaxes between beats in patients with weakened heart pumping. Researchers will use heart ultrasound scans to measure changes in 70 Egyptian patients bef…

This study aims to see if giving the antibiotic moxifloxacin in repeated, short courses is better than standard care at preventing lung infection flare-ups in adults with bronchiectasis. It will enroll 140 adults who have had at least two flare-ups in the past year. The main goal…

This study is testing a new method to guide treatment for adults with septic shock, a life-threatening infection. The goal is to see if using a special arm cuff to measure blood flow pressure, along with a kidney ultrasound, can help doctors give the right amount of fluids and me…

This study compares two surgical techniques for correcting a common residual foot deformity in children whose clubfoot has returned after initial treatment. It will enroll 40 children aged 5-10 with relapsed clubfoot and residual metatarsal adductus. Researchers aim to determine …

This study is testing a less invasive 'keyhole' surgery to drain serious liver infections called abscesses. It will compare this laparoscopic method to traditional open surgery to see if it leads to fewer complications, shorter hospital stays, and faster recovery for patients. Th…

This study compares two medications for children with dilated cardiomyopathy, a condition where the heart muscle is weak and enlarged. Researchers want to see if a newer drug (sacubitril/valsartan) works better than the older standard drug (captopril) at improving heart pumping s…

This study is testing a behavioral program that uses rewards to help people with opioid addiction stay drug-free during and after hospital treatment. It will involve 55 adults receiving inpatient care at Assiut University Hospital. The main goal is to see if this reward-based app…

This study aims to see which of two dietary supplements works better to reduce fat in the liver for people with metabolic-associated fatty liver disease (MAFLD). It will involve 200 adults diagnosed with fatty liver. Researchers will measure changes in liver fat using medical ima…

This study compares two ways to close skin after open appendix removal surgery. Researchers want to see if a hidden stitch with a small drain tube works better than traditional visible stitches at preventing wound infections. They'll measure infection rates, pain, scar appearance…

This study is testing whether a single surgery to remove a blocked kidney stone is safe and effective for patients who already have some reduced kidney function. Usually, these patients might get a temporary tube placed first, then have the stone removed later. Researchers want t…

This study aims to find the best way to manage small leftover spots in rectal cancer patients who have already had chemoradiation. It will compare two approaches: surgically removing these spots versus closely monitoring them without immediate removal. The goal is to see which me…

This study compares two surgical tools used to control bleeding during thyroid removal surgery. Researchers want to see if a newer tool called LigaSure leads to shorter surgery times and fewer complications like nerve damage or low calcium levels compared to the standard bipolar …

This study aims to compare two different surgical procedures for treating a narrowing of the spinal canal in the neck (cervical stenosis). It will enroll patients who need surgery to relieve pressure on their spinal cord and nerves. Researchers will track which procedure—laminopl…

This study compares two different cage designs used in lower back fusion surgery for people with severe disc herniation and chronic back pain. It aims to see which cage type—two straight cages placed on both sides or a single curved 'banana' cage placed on one side—leads to bette…

This study is testing a surgical technique to improve recovery from traumatic nerve injuries in the arm. Doctors will wrap a small piece of the patient's own vein around the repaired nerve to act as a protective barrier. The goal is to see if this reduces painful scar tissue form…

This study is testing whether using a non-invasive breathing machine (BiPAP) at home can help people with severe COPD. It will involve 40 patients who have recently been discharged from the hospital and still have high carbon dioxide levels in their blood. Researchers will check …

This study is testing if injecting chemotherapy directly into pancreatic tumors using a special ultrasound-guided needle can help control the cancer better than standard IV chemotherapy alone. It will involve 20 adults with locally advanced pancreatic cancer who have not had prio…

This study aims to see if a simple, non-invasive intestinal ultrasound can be as accurate as a colonoscopy for monitoring active ulcerative colitis. Researchers will compare ultrasound scores with colonoscopy results in 200 adult patients with active disease. The goal is to find …

This study aims to improve how doctors plan surgery for ovarian cancer. Researchers will compare three methods—CT scans, a minimally invasive 'keyhole' surgery look, and the final open surgery—to see which best predicts if all visible tumor can be safely removed. The goal is to h…

This study aims to see how well and how safely a procedure called bronchoscopy works to remove objects that children have accidentally swallowed and breathed into their lungs. It will involve 75 children under 18 years old who are suspected of having swallowed a foreign object. R…

This study aims to see if a new, simpler device (Electrical Cardiometry) is as accurate as the current standard method (Echocardiography) for measuring how well the heart is pumping in patients with septic shock. It will involve 100 adult patients with septic shock. The goal is t…

This study aims to create and test a new scoring system called the STAR score. It combines a quick bedside ultrasound scan with simple blood tests to help doctors predict if an adult patient with blunt abdominal trauma (like from a car crash or fall) has serious internal injuries…

This study aims to see if adding a quick, painless ultrasound scan of the neck to a standard airway exam can better predict which patients will be difficult to place a breathing tube in during surgery. About 160 adults having planned surgery will be randomly assigned to get eithe…

This study aims to find out how well a standard heart ultrasound (echocardiogram) can detect early signs of pulmonary hypertension (high blood pressure in the lungs) in people with scleroderma. It will enroll 35 adults with confirmed scleroderma. The goal is to improve early dete…

This study aims to see if combining a simple blood test for H. pylori bacteria with a painless stomach ultrasound can accurately predict which patients with stomach ulcers are at high risk for serious complications like bleeding. Researchers want to create a scoring system to hel…

This study aims to find less invasive ways to detect dangerous swollen veins (varices) in the food pipes of children with high blood pressure in their liver veins. Researchers will test if simple blood tests and ultrasound measurements can accurately predict which children have t…

This study aims to see if measuring a baby's liver size during pregnancy ultrasounds can reveal how gestational diabetes is affecting the fetus. Researchers will compare liver measurements in 115 pregnant women with and without diabetes to see if liver size correlates with blood …

This study is testing whether artificial intelligence (AI) can help doctors more accurately tell the difference between two common types of arthritis in older patients. Researchers will compare how well an AI system analyzes medical scans against the assessments of expert radiolo…

This study is testing whether using ultrasound scans after hand tendon surgery can help doctors spot healing problems earlier than a standard physical exam. Researchers will follow 50 adults who have had this surgery to see if the scans lead to faster treatment decisions and bett…

This study is testing if a special pressure test of the rectum and anus can help doctors better understand and treat severe, long-term constipation in children. It will involve 54 children aged 4 to 18 whose constipation hasn't improved with standard treatments. The goal is to se…

This study is testing a special type of ultrasound called shear-wave elastography to see if it can detect early tendon inflammation (enthesitis) in people with psoriasis, which is a key sign of developing psoriatic arthritis. Researchers will compare this new method to standard u…

This study aims to see if a protein in the blood called sCD163 can help doctors detect HELLP syndrome earlier. HELLP is a serious pregnancy complication involving blood and liver problems. Researchers will compare sCD163 levels in 70 pregnant women with and without HELLP to see i…

This study aims to understand how well a procedure called endoscopy works to find the causes of digestive problems in children. Doctors will look inside the digestive systems of 150 children at Assiut University Children Hospital who have symptoms like ongoing diarrhea, vomiting,…

This study is testing whether a specialized ultrasound procedure done during an endoscopy can more accurately determine if a thickening in the upper digestive tract (esophagus, stomach, or duodenum) is cancerous or benign. It will involve 43 adults whose CT or MRI scans showed th…

This study aims to find out if two simple measurements from a routine blood test can help predict dangerous blood clots in the legs of patients on breathing machines in the intensive care unit. Researchers will follow 100 patients to see if higher levels of these markers are link…

This study aims to create a better way to check amniotic fluid levels during pregnancy. Researchers will scan 70 pregnant women to see if adding measurements of the baby's bladder to standard ultrasound checks improves accuracy. The goal is to develop a new scoring model that hel…

This study is testing a new scoring system called the STARZ score to see if it can predict kidney injury in newborns earlier than current blood tests. Researchers will follow 140 newborns in a hospital's intensive care unit to check if the score accurately identifies which babies…

This study aims to see how helpful a medical camera test (upper endoscopy) is for finding physical causes of long-term stomach pain in children. It will observe about 130 children under 18 who have had pain for at least three months and are getting the test as part of their norma…

This study aims to see if a painless ultrasound scan of the gut, combined with a standard blood test, can accurately track the severity of celiac disease. Researchers want to find a less invasive way to monitor patients than the current method, which requires a biopsy. The study …

This study aims to see if a quick, non-invasive ultrasound scan of a major vein is as good as a traditional, more invasive pressure monitor for detecting low blood volume in patients with shock. It will enroll 80 adult patients arriving at the emergency department in shock. Resea…

This study aims to see if routine mammograms and ultrasounds can predict the molecular subtype of a patient's breast cancer, which currently requires an invasive biopsy. Researchers will analyze imaging features from 122 women with confirmed breast cancer and compare them to biop…

This study aims to find a better way to tell if patients with severe septic shock need more IV fluids. It will compare a traditional pressure measurement with a newer ultrasound method in 70 adult patients. The goal is to help doctors give the right amount of fluid—enough to help…

This study aims to see if combining two advanced MRI techniques with standard MRI can better identify the exact spot in the brain where seizures start in people with temporal lobe epilepsy. It will involve 78 participants who have this type of epilepsy but whose standard MRI scan…

This study aims to see which of two emergency room checklists is better at predicting which sepsis patients are most likely to die. Researchers will compare a newer, more detailed score (REDS) against a simpler, widely-used score (qSOFA) in 80 adult patients with suspected severe…

This study aims to see how useful a camera inserted into the stomach and intestines (endoscopy) is for finding the cause when a child is not growing or gaining weight as expected. It will involve 50 children aged 6 months to 18 years who have poor weight gain and possible gut sym…

This study is testing a special, non-invasive heart scan to see if it can detect and measure early scarring in the heart muscle of people with long-term thyroid disease. The goal is to find this damage earlier, when it might be easier to manage. The study will enroll 40 adults wi…

This study is testing whether adding a special MRI sequence called T2 mapping to standard knee scans can help doctors detect early osteoarthritis changes in cartilage. Researchers will compare scans from 28 healthy people and 28 people with early knee arthritis to see if T2 mappi…

This study aims to test a simple scoring system that uses a patient's age and routine blood test results to predict a dangerous abdominal infection called SBP in people with liver cirrhosis. The goal is to provide a faster way to identify patients who need urgent antibiotic treat…

This study aims to test a simpler lab method for detecting bacteria that are resistant to a last-resort antibiotic called colistin. Researchers will collect bacteria samples from 90 hospitalized patients with hard-to-treat infections. They will compare the new test against the cu…

This study aims to find better ways to detect nerve damage (neuropathy) in people with diabetes. Researchers will test 75 adults with and without diabetes using a combination of nerve tests, ultrasound, and heart rate measurements. The goal is to see if these methods together can…

This study is testing whether a tool called the BIND score helps doctors better identify and manage severe jaundice in newborns. It will involve 80 newborns in intensive care who need strong light therapy. The goal is to see if using this score leads to earlier detection and bett…

This study aims to find out if a standard CT scan (CT KUB), often used for kidney stones, can accurately tell the difference between harmless and potentially harmful kidney cysts. It will involve 200 patients who have kidney cysts found on their scans. Researchers will compare th…

This study is testing a new, less invasive biopsy method to improve the diagnosis of uterine masses. Researchers will compare results from a simple outpatient biopsy to the standard surgical biopsy in 42 women. The goal is to see if this easier test can accurately tell benign fro…

This study aims to find out if a special type of CT scan is as accurate as a biopsy for telling whether a growth in the pancreas is cancerous or not. It will enroll 50 adults who have a pancreatic lesion that needs further checking. Researchers will compare the results from the s…

This study aims to see if a special type of MRI scan, called vessel wall MRI, can accurately tell the difference between two conditions that cause strokes: a buildup of plaque in the brain's arteries (ICAD) and inflammation of the blood vessels (vasculitis). Researchers will enro…

This study aims to see if detailed CT scans can help doctors better identify the specific heart structures and related problems in children born with Tetralogy of Fallot, a complex heart defect. It will enroll 37 children up to age 12 who have this condition. The goal is to provi…

This study aims to see how often a stomach scope (endoscopy) finds physical problems in children with long-term belly pain. It will include 100 children aged 6 to 18 who have had unexplained pain for months. The goal is to understand if this procedure is a useful tool for finding…

This study aims to see if a shorter, 10-minute reading from a fetal heart rate monitor is just as good at checking a baby's health during labor as the standard 30-minute reading. Researchers will compare both methods in 200 low-risk pregnant women in active labor. The goal is to …

This study aims to see if measuring two specific proteins (Talin-1 and Cripto-1) in the blood can help doctors detect colorectal cancer. Researchers will compare blood samples from 70 people with colorectal cancer to samples from healthy people. The goal is to find a better, simp…

This study aims to find out if a newer type of scan (called 18F-PSMA PET/CT) is better than the standard CT scan for checking prostate cancer. It will look at 59 men with prostate cancer to see which scan is more accurate for finding where the cancer is, seeing if treatment is wo…

This study is testing a special type of MRI scan that doesn't use contrast dye to see if it can accurately tell how serious a child's brain tumor is before surgery. It will involve 20 children with brain tumors who haven't had prior treatment. The goal is to provide doctors with …

This study aims to see how well a specific ultrasound scoring system, called O-RADS, can tell the difference between non-cancerous and cancerous ovarian masses. It will involve 80 women, aged 18 to 70, who are found to have an ovarian cyst or mass during a routine ultrasound. Res…

This study aims to find the most common causes of non-inflammatory joint problems in children at Assiut University Children's Hospital. Researchers will carefully examine 35 children with joint stiffness or deformity but no signs of typical joint inflammation. The goal is to impr…

This study aims to test a simple Arabic questionnaire called SAMANTA to see if it can reliably identify women with heavy menstrual bleeding. Researchers will give the questionnaire to 120 women of reproductive age to check how well it works. The goal is to create an easy-to-use t…

This study aims to see if a quick, non-invasive scan (FibroScan) can be as accurate as a standard liver biopsy for measuring fat in the livers of potential living donors. Researchers will compare results from both tests in 100 adult donors to determine if the scan is a reliable a…

This study is testing a special type of ultrasound, done during a scope procedure, to see if it can accurately tell whether unusual growths in the chest or digestive tract are cancerous or not. It will involve about 35 people who have these masses. The goal is to see if this tool…

This study aims to see if 3D MRI volume measurements of breast masses match the actual tumor size found during surgery. Researchers will compare MRI scans with pathology results from 59 women with operable breast cancer. The goal is to improve how doctors measure tumors to better…

This study aims to see if MRI scans are better than standard X-rays at spotting early joint damage in adults with hemophilia who have had repeated knee bleeds. Researchers will compare two scoring systems on images from 95 participants to see which method gives a clearer picture …

This study aims to see how accurate and useful ultrasound is for finding abnormal fluid in the abdomen (called ascites) and figuring out what's causing it. Researchers will enroll 125 patients at Assiut University Hospital who are suspected of having this condition. The goal is t…

This study aims to test a new ultrasound measurement to detect fetal anemia, a serious condition where an unborn baby has low red blood cells. Researchers will compare this new method against the current standard technique in 20 pregnancies. The goal is to see if the new measurem…

This study aims to develop a simple blood test to diagnose inflammatory bowel disease (IBD). Researchers will measure two specific genetic markers in the blood of 62 newly diagnosed patients to see if they can accurately identify IBD. The goal is to find a less invasive alternati…

This study aims to create a more accurate ultrasound model to tell the difference between two serious pregnancy conditions: placenta accreta and uterine scar separation. It will involve 50 women in their third trimester who have a low-lying placenta and a history of C-section. Th…

This study is testing if adding a medication called misoprostol, given as a rectal suppository, to the standard treatment (oxytocin) can better reduce blood loss during and after a planned cesarean section. It will compare two groups of women: one gets the standard treatment alon…

This study is testing if a two-part injection treatment works better than the standard single treatment for reducing arm stiffness (spasticity) after a stroke. Researchers will compare giving a phenol injection near the shoulder plus a Botox injection in the forearm against givin…

This study aims to find the best surgical method for treating severe cases of gynecomastia, a condition of enlarged breast tissue in men that can cause significant emotional distress. Researchers will compare three different skin incision and tissue removal techniques in 45 adult…

This study is testing whether a non-invasive brain stimulation technique can help reduce symptoms of ADHD and autism in children and adolescents. Participants aged 6-19 will receive either real or fake magnetic pulses to the forehead area over three weeks. The main goal is to see…

This study is testing a new surgical method for lifting sagging breasts. Doctors will use the patient's own breast tissue to create an internal support structure (an 'internal bra') and add fat grafting to improve shape and fullness. The goal is to see if this technique provides …

This study is testing if a high-energy shockwave machine, normally used to break up kidney stones, can be safely adjusted to treat erectile dysfunction (ED). The goal is to see if low-energy shockwaves can improve blood flow to the penis and help with ED. The study will enroll 30…

This study is testing a specific type of wrist fusion surgery called lunocapitate fusion. It aims to reduce pain and improve hand function in adults with advanced wrist arthritis caused by an old scaphoid fracture that never healed properly. Researchers will follow 35 patients fo…

This study aims to find the best way to close the skin after a child's stoma reversal surgery. It will compare a traditional straight-line stitch with a newer circular 'purse-string' stitch in 50 children. The main goals are to see which method leads to fewer wound infections and…

This study aims to find the best way to manage pain in young children after hip surgery. Researchers will compare two different medicines added to standard pain relief to see which one works better and lasts longer. The goal is to help children recover more comfortably with fewer…

This study aims to find the best two-drug combination to prevent nausea and vomiting after gallbladder removal surgery in women. Researchers will compare two different drug pairs given before surgery to see which one works better. The goal is to improve comfort and recovery for p…

This study aims to find the best way to manage pain for children after kidney surgery. It will compare two different types of safe, ultrasound-guided nerve blocks to see which one provides better and longer-lasting pain relief. The goal is to help children recover more comfortabl…

This study is testing if a targeted nerve block in the neck can better control pain after facial and jaw surgeries. It will compare this approach to standard general anesthesia. The goal is to see if the nerve block reduces the need for strong painkillers and helps patients feel …

This study aims to find out which of two common sedative drugs works better for keeping men comfortable and stable during a minor surgical procedure to treat varicoceles. Researchers will compare dexmedetomidine and ketamine in about 58 healthy male patients who are having the su…

This study is testing whether a drug called dexmedetomidine, given as a breathing treatment (nebulization), can help control dangerous spikes in blood pressure when a breathing tube is placed during C-section surgery. It will involve 100 women with severe preeclampsia who are hav…

This study is testing if giving the numbing medication lidocaine through an IV during and after gallbladder surgery can reduce inflammation and pain. Researchers want to see if this helps patients get their digestive system working again sooner, feel less pain, and leave the hosp…

This study will test if taking a daily low-dose tadalafil pill helps improve bothersome urinary symptoms, like urgency and frequency, in the months after a common prostate surgery for enlarged prostate. It will involve 40 men who are having the surgery. Researchers will compare s…

This study aims to find the best way to manage pain after surgery to correct hypospadias, a common birth defect in boys. It will compare two different nerve block techniques, both given with a pain medication called dexmedetomidine, in 66 children aged 1 to 6 years. The main goal…

This study is testing whether intravenous (IV) infusions of lidocaine, ketamine, or a combination of both can safely reduce severe facial pain that hasn't responded to other treatments. It will involve 105 adults with conditions like trigeminal neuralgia. The main goal is to see …

This study aims to find the best way to improve the appearance of facial acne scars. It will compare a treatment using a person's own processed fat (nanofat) alone to the same treatment combined with either a platelet-rich gel or a microneedling procedure. The goal is to see whic…

This study aims to find the best medication to reduce coughing and a sore throat after sinus surgery. Researchers will compare three drugs—dexmedetomidine, lidocaine, and magnesium sulfate—in 102 adults undergoing a common sinus procedure. The goal is to see which drug most effec…

This study aims to see which of two common drugs, propofol or lidocaine, works better to prevent or reduce agitation when children wake up from tonsil surgery. It will involve 82 healthy children aged 4 to 7. The main goal is to find a safer, more comfortable way for kids to reco…

This study aims to see if taking two low-dose erectile dysfunction (ED) pills together works better than taking one standard pill. It will involve about 142 men with ED who are in a stable relationship. Participants will try different pill combinations in a random order to compar…

This study is testing if a simple step during pancreas surgery can help patients recover faster. During the operation, surgeons will gently stretch the valve that connects the stomach to the small intestine. Researchers want to see if this reduces common problems like severe naus…

This study is testing if adding the anesthetic ketamine to a standard pain-relief rinse can better control pain after gallbladder removal surgery. It will compare two groups of 30 patients each to see which rinse leads to less pain and lower use of strong opioid painkillers in th…

This study compares two approaches to help people with long-term dizziness from inner ear problems. Researchers will test whether virtual reality exercises work better than traditional balance therapy at reducing symptoms. The trial will involve 40 adults who have experienced diz…

This study aims to find the best way to treat depressed acne scars, which can affect a person's self-esteem and quality of life. Researchers will compare three approaches on 42 adult participants: a standard procedure called subcision, subcision combined with a special laser, and…

This study aims to find a better way to manage pain after shoulder surgery. It will compare a new combination of two nerve blocks to the standard single nerve block, focusing on whether the new method provides similar pain relief while causing fewer breathing difficulties. The re…

This study aims to see if making urine less acidic with potassium citrate can relieve the painful, urgent symptoms of a bladder infection as effectively as a standard antibiotic. It will involve 50 women aged 18-50 with uncomplicated UTIs. Researchers will compare symptom relief …

This study is testing if adding a drug called dexmedetomidine to a standard numbing injection (a nerve block) works better for pain relief after major abdominal cancer surgery. It will involve 54 adults having surgery for cancers like stomach or liver cancer. The main goal is to …

This study aims to see which of two common anesthesia drugs works better to control pain and keep the heart stable during major abdominal cancer surgery. It will compare dexmedetomidine and fentanyl, given by IV drip, in 70 adult patients. Researchers will use a special monitor t…

This study is testing a 3-month rehabilitation program for people with COPD. The program combines hospital sessions with exercises done at home. Researchers want to see if this tailored approach helps patients walk farther, breathe easier, and feel better in their daily lives.

This study compares two different drugs (dexmedetomidine and magnesium sulphate) when added to standard spinal anesthesia for patients having hip fracture surgery. The goal is to see which one works better to make the numbness last longer, keep blood pressure and heart rate stabl…

This study aims to find out which type of anesthesia causes less nausea and vomiting after laparoscopic gynecologic surgery. It will compare a method using only intravenous drugs (TIVA) to one using inhaled gases. The goal is to improve patient comfort and recovery by reducing th…

This study compares two approaches to pain control during and after gallbladder removal surgery. Researchers want to see if using opioid-free anesthesia reduces pain and nausea while helping patients recover faster. The study will involve 110 adults having elective gallbladder su…

This study aims to find out which of two common anesthetic drugs, dexmedetomidine or midazolam, is better at preventing shivering in trauma patients having leg surgery with spinal anesthesia. Shivering is a frequent and uncomfortable side effect that can complicate recovery. The …

This study is testing if placing a small drain tube after gynecologic keyhole surgery can reduce shoulder pain, a common and uncomfortable side effect. The pain is thought to be caused by leftover gas irritating the diaphragm. Researchers will compare pain levels and recovery in …

This study is testing a special recovery plan for mothers who have an unplanned (emergency) cesarean section. The plan includes steps like better pain management, early movement, and timely eating to help women heal faster and feel better after surgery. Researchers will compare r…

This study aims to find the best way to reduce pain after arm surgery. Researchers will compare two different medications added to a standard numbing injection to see which one provides longer-lasting pain relief. The study involves 66 adults having planned upper arm, elbow, or h…

This study aims to see if inhaling a mucus-thinning drug (N-acetylcysteine) through a nebulizer is as good as or better than receiving it through an IV drip for adults hospitalized with a bronchiectasis flare-up. It will measure how well the drug helps clear thick mucus from the …

This study aims to see which of two minimally invasive procedures works better for reducing long-term heel pain from plantar fasciitis. It will compare pulsed radiofrequency ablation, which uses gentle electrical pulses to calm nerves, to a standard steroid injection. The trial w…

This study aims to measure and understand the body composition—specifically fat, muscle, and bone mass—in children with a severe inherited blood disorder called beta thalassemia major. Researchers will use a simple, non-invasive tool to scan 115 children aged 5-18 who receive reg…

This study aims to identify early signs that can predict how well children will recover from Guillain-Barré Syndrome (GBS), a rare autoimmune disorder that causes muscle weakness and paralysis. Researchers will follow 80 children aged 1 month to 18 years who are diagnosed with GB…

This study aims to understand how the amount of brain tumor removed during surgery affects patient survival when followed by standard chemotherapy and radiation. Researchers will observe 50 adults with glioblastoma who have already had surgery and standard follow-up treatment. Th…

This study aims to understand how specific genetic characteristics in patients with chronic lymphocytic leukemia (CLL) affect their response to treatment and overall health outcomes. Researchers will collect detailed medical history, perform physical exams, and analyze blood samp…

This study aims to understand why cesarean section rates are so high in two hospitals in Assiut, Egypt. Researchers will review medical records of 770 women who had C-sections in 2026, using a World Health Organization classification system to identify which groups of women contr…

This study aims to see if simple blood markers, like ratios of different blood cells, can help predict how severe sepsis will be and whether a patient might survive. Researchers will compare these blood markers to standard clinical scoring systems used in intensive care. The goal…

This is a laboratory study, not a treatment trial. Researchers are collecting bacteria from patients with urinary tract infections to test if nanoparticles made from a natural substance called chitosan can stop bacteria from forming protective films (biofilms). They will test the…

This study aims to measure how common depression, anxiety, stress, and burnout are among people being treated for heart disease and the healthcare workers who care for them. Researchers will survey about 380 patients and all available staff in a cardiology department. The goal is…

This study aims to understand the relationship between H. pylori stomach infections and psychological factors like anxiety and depression. Researchers will observe 130 patients with H. pylori gastritis to see how common these mental health symptoms are and if treating the infecti…

This study aims to understand how often children born with heart defects also have underlying chromosomal abnormalities. Researchers will examine 138 children with confirmed congenital heart disease at two hospitals in Egypt, performing blood tests to look for genetic changes. Th…

This study aims to understand how type 2 diabetes affects blood platelets and whether these changes relate to inflammation and blood sugar levels. Researchers will compare blood test results from 100 diabetes patients and 100 healthy people during a single clinic visit. The study…

This study aims to better understand what causes congenital ptosis (droopy eyelid present from birth) by examining the eyelid muscle tissue during surgery. Researchers will study tissue samples from 153 children undergoing corrective surgery to see how the muscle developed abnorm…

This study aims to understand if abnormal blood electrolyte levels (like sodium and potassium) can help predict how critically ill children will fare in the pediatric intensive care unit (PICU). Researchers will observe 200 children admitted to the PICU, analyzing their electroly…

This study aims to understand if measuring a specific protein (Tim-3) on certain blood cells can help doctors better assess how active ankylosing spondylitis is in a patient. Researchers will enroll 81 adults with the condition to see if Tim-3 levels correlate with other disease …

This study aims to find the best and easiest way to use bedside ultrasound to check how much blood a severely injured patient has lost. Researchers will compare three different veins in the neck, groin, and abdomen, scanning patients before and after they receive fluids in the em…

This study aims to understand the connection between vitamin D deficiency and symptom flare-ups in people with Crohn's disease or ulcerative colitis. Researchers will measure vitamin D levels in the blood of 100 adults with active inflammatory bowel disease (IBD). The goal is to …

This study aims to better understand how severe infections (sepsis) can damage the heart in critically ill children. Researchers will observe 84 children aged 1 month to 18 years who have sepsis, measuring their heart function to identify early warning signs of heart injury. The …

This study aims to understand how common brain bleeding is in very premature babies, what factors make it more likely to happen, and what the short-term health outcomes are. Researchers will observe 300 preterm infants in a neonatal intensive care unit (NICU), using brain scans t…

This study aims to understand if having high levels of uric acid in the blood is connected to developing fatty liver disease and liver scarring in obese adults. Researchers will observe 111 participants to see how common fatty liver is in this group and measure their uric acid le…

This study aims to see how often infections happen in the surgical wound after a C-section. Researchers will follow 105 women for 30 days after their surgery. They will also check how closely the hospital staff follow recommended steps to prevent these infections.

This study aims to understand seizures in newborns admitted to a hospital's intensive care unit. Researchers will observe up to 139 babies under 30 days old who have seizures to learn how common they are, what causes them, and how the babies fare during their hospital stay. The g…

This study aims to see if measurements of blood platelets, which are easy to get from a standard blood test, can help doctors understand how active a patient's inflammatory bowel disease (IBD) is. Researchers will enroll 84 adults with Crohn's disease or ulcerative colitis to che…

This study aims to understand if missing scheduled dialysis sessions increases the risk of serious heart problems like heart attacks or strokes within 72 hours. Researchers will follow 225 adults with kidney failure who receive regular hemodialysis three times per week. The goal …

This study aims to understand how common obsessive-compulsive symptoms are in people recovering from substance use disorders. Researchers will compare 51 adults with substance use disorders to 51 healthy adults, using questionnaires and interviews to measure symptoms and quality …

This study aims to identify which non-vascular factors—like nerve damage, poor blood sugar control, or nutrition—make diabetic foot ulcers worse or more likely to come back. It will observe 100 adults with diabetes and existing foot ulcers for one year, tracking wound size, heali…

This study aims to see if measuring a protein called uromodulin in the blood can help doctors predict how well a patient's kidneys will recover after a severe infection (sepsis) causes sudden kidney injury. Researchers will measure this protein in 30 adult patients with sepsis-re…

This study aims to understand how Pseudomonas aeruginosa, a dangerous bacteria that causes hospital infections, becomes resistant to multiple antibiotics. Researchers will examine 80 bacterial samples from patients to see how a specific gene and the bacteria's ability to form pro…

This study aims to understand how often adults with low platelet counts also have an enlarged spleen. Researchers will observe 100 patients to see if having a larger spleen leads to different complications or affects how well treatments work. The goal is to gather information to …

This study aims to understand how often and what types of sleep breathing problems occur in people with systemic sclerosis (scleroderma). Researchers will monitor the sleep of 30 adult patients overnight to gather detailed information. The goal is to fill a knowledge gap and see …

This study aims to find biological markers in blood and spinal fluid that can help doctors predict how children with encephalitis (brain inflammation) will recover. Researchers will measure two specific proteins in 90 children aged 1 month to 18 years who are hospitalized with th…

This study aims to understand the daily challenges faced by people living with Wilson's disease and their families in Upper Egypt. Researchers will interview 66 patients to learn about their difficulties with dietary restrictions, travel to clinics, emotional burdens, and access …

This study aims to understand how well general practitioners diagnose and treat H. pylori, a common stomach infection. Researchers will survey 300 doctors in Egypt to measure their knowledge, attitudes, and current practices. The goal is to identify gaps in training or barriers i…

This study aims to understand if having low iron levels, with or without anemia, increases the risk of irregular heartbeats (arrhythmias) in people hospitalized for heart failure. Researchers will enroll 300 adult patients and compare their iron status with their heart rhythm dat…

This study aims to see if a specific ultrasound measurement of blood flow in the scrotum can predict how well varicocele surgery improves sperm quality. Researchers will enroll 100 men with varicoceles confirmed by ultrasound. They will measure blood reflux volume before surgery …

This study aims to document the symptoms, lab results, and current treatments of 30 patients with Behçet's disease at a major hospital in Upper Egypt. Researchers will observe and record information but will not test any new treatments. The goal is to better understand how this c…

This study aims to better understand myocarditis, an inflammatory heart condition, in children. Researchers will follow 100 children aged 1 to 18 who are diagnosed with the disease at a hospital in Egypt for one year. The goal is to learn how different forms of the illness appear…

This study aims to see if a special type of ultrasound can find hidden joint and tendon inflammation in people with Crohn's disease or ulcerative colitis (IBD), even when they don't have joint pain. Researchers will test 81 IBD patients who don't have a diagnosis of arthritis. Th…

This study aims to get a complete picture of how standard treatment helps people with severe plaque psoriasis. Researchers will follow 45 adults receiving treatment, checking their skin, looking at it under a special microscope, and asking how the disease affects their daily life…

This study will follow 30 children under 18 who have surgery for specific brain tumors at Assiut University Hospital. Researchers will track how well children recover after surgery and look for factors—like tumor type or surgery details—that might affect their health outcomes. Th…

This study aims to understand the connection between sleep problems and nervous system function in older adults with heart disease. Researchers will observe 210 patients to identify common risk factors and see how these issues might affect heart health. The goal is to gather know…

This study aims to see if measuring certain proteins in the blood can help doctors predict how severe a COPD flare-up will be. Researchers will enroll 75 adults hospitalized for a COPD attack. They will check blood levels of a lung protein and other inflammation markers to see if…

This study aims to find out if simple calculations from a routine blood test can predict how severe a case of acute pancreatitis will become. Researchers will analyze blood samples from 100 adult patients treated for pancreatitis to see if certain cell ratios correlate with disea…

This study aims to identify which early symptoms and signs can predict if a child's pneumonia will become severe. Researchers will observe 67 children, aged 1 month to 5 years, who are admitted to a hospital in Egypt with pneumonia. By carefully tracking their symptoms, test resu…

This study aims to understand normal brain blood flow patterns in healthy full-term and premature newborns. Researchers will use a safe, non-invasive ultrasound scan to measure blood flow in the brain's main arteries during the first two days of life. The goal is to create standa…

This study aims to find a simple blood test to screen for a serious lung complication in people with rheumatoid arthritis (RA). Researchers will measure levels of two specific proteins (MMP7 and MMP9) in 81 participants, including RA patients with and without lung disease, and he…

This study aims to understand how common intestinal parasite infections are in malnourished children in Assiut, Egypt. Researchers will compare 116 children who are underweight or stunted with healthy children of the same age. The goal is to gather information about the link betw…

This study aims to observe and measure two specific proteins, CD85d and CD305, in the blood cells of 180 people newly diagnosed with B-cell cancers. The goal is to understand if these proteins can help doctors better classify the specific type of cancer and predict when a patient…

This study aims to understand how changes in the tiny blood vessels at the back of the eye relate to vision loss in people with multiple sclerosis (MS). Researchers will use a special, non-invasive eye scan (OCT-A) and standard vision tests on 32 MS patients. The goal is to see i…

This study aims to see if a score calculated from three common blood tests (CALLY index) can help predict which heart attack patients might face complications after emergency artery-opening procedures. Researchers will follow 140 patients undergoing emergency heart attack treatme…

This study aims to understand how two different types of rheumatoid arthritis (RA) treatments affect the body. Researchers will compare patients taking newer JAK inhibitor drugs to those on traditional medications. They will look at blood test results and detailed ultrasound imag…

This study aims to measure levels of a specific thyroid antibody in people with diabetes to better understand the link between these two conditions. Researchers will enroll 112 adults with diabetes who do not have known thyroid problems. The goal is to gather information that cou…

This study aims to find out how many people with fatty liver disease (MAFLD) also have a common stomach infection called H. pylori. Researchers will test 200 adults with MAFLD for H. pylori using a stool test. The goal is to see if finding and treating this infection could be a n…

This study aims to understand what causes anemia in newborns admitted to intensive care and how it affects their health. Researchers will observe 40 infants to identify risk factors and track outcomes like hospital stay length and need for blood transfusions. The study does not t…

This study aims to find a faster, more objective way to confirm if a nerve block for arm surgery is successful. Researchers will test if simple measurements from a finger clip sensor and an ultrasound can predict a good block within 15 minutes. The goal is to improve the experien…

This study aims to understand why some breast cancers stop responding to standard hormone therapy. Researchers will analyze stored tumor tissue from 70 patients who previously received treatment, looking for specific protein patterns. The goal is to find markers that might predic…

This study aims to understand how common obesity is among people with a common type of fatty liver disease (MASLD). Researchers will also closely examine a group of patients who have this liver disease but are not overweight, to learn more about their health characteristics. The …

This study aims to understand the relationship between metabolic syndrome—a cluster of conditions like obesity and high blood pressure—and gastroesophageal reflux disease (GERD), commonly known as acid reflux. Researchers will observe 50 adult patients with metabolic syndrome to …

This study aims to see if two different types of standard knee X-rays give surgeons the same measurement for planning a knee realignment surgery. Researchers will compare angle measurements from full-leg standing X-rays and a bent-knee X-ray view in 49 patients. The goal is to un…

This study aims to find out if measuring a patient's internal belly fat with a CT scan can help doctors predict how well biologic drugs will work for their ulcerative colitis. Researchers will scan 200 adult patients before and after starting treatment to see if changes in fat re…

This study aims to understand if having obesity affects how well standard treatments work for people with Crohn's disease or ulcerative colitis. Researchers will follow 120 adult patients already on treatment to see if their body weight is linked to their treatment response and d…

This study aims to see if measuring a specific fat-protein in the blood (called Lipoprotein(a)) can help predict who is at higher risk for future heart problems after getting an elective stent. Researchers will follow 156 patients for two years after their procedure to track any …

This study aims to understand how frailty (physical weakness common in older age) influences treatment choices and short-term recovery in elderly patients who have had a heart attack. Researchers will follow 645 patients aged 65+ to see if adding a frailty assessment to standard …

This study aims to understand how heart procedures affect mental health in people with congenital heart disease. Researchers will follow 60 patients, assessing their psychological well-being before their procedure, then one month and three months afterward. The goal is to learn h…

This study aims to understand and improve how teenagers in Assiut, Egypt, think about and seek help for mental health issues. Researchers will first survey about 270 students to learn their current knowledge and attitudes. Then, 150 students will be split into two groups to test …

This study aims to understand how muscle loss (sarcopenia) affects treatment outcomes for people with inflammatory bowel disease (IBD). Researchers will use routine CT scans to measure muscle mass in 50 adult patients who are receiving biologic therapies. The goal is to determine…

This study aims to find out which method is better at predicting if a first-time mother will have a successful vaginal delivery after her labor is medically induced. Researchers will compare a traditional physical exam (the Bishop score) with an ultrasound measurement of the cerv…

This study aims to find out how common schistosomiasis (a parasitic worm infection) is in Assiut, Egypt. Researchers will test stool and urine samples from 359 people aged 5 and older who are suspected of having the infection. The goal is to identify the types of parasites presen…

This study aims to understand if low magnesium levels in the blood are connected to sleep problems in people with major depression. Researchers will measure magnesium levels and use questionnaires about depression and sleep quality in 90 participants. The goal is to see if magnes…

This study aims to determine if there's a difference in sperm retrieval success between the right and left testicles in men with non-obstructive azoospermia (a condition where no sperm is found in semen). Researchers will examine 80 men undergoing a surgical procedure to extract …

This study aims to understand the genetic causes of birth defects and developmental delays in children. Researchers will observe the results of a specific genetic test (karyotyping) in 75 children aged 1 month to 12 years. The goal is to see how often this test finds a cause and …

This study aims to understand if a standard laser treatment for a severe form of diabetic eye disease affects the health of cells on the clear front part of the eye (the cornea). Researchers will measure these cells in 45 patients before the laser treatment, and again one week an…

This study aims to see if the way doctors at Assiut University Heart Hospital implant pacemakers and similar devices matches the best-practice guidelines from Europe. It will follow 200 patients to see if following these guidelines more closely leads to fewer complications like i…

This study aims to find better ways to tell the difference between Multiple Sclerosis (MS) and a similar disease called Neuromyelitis Optica Spectrum Disorder (NMOSD). Researchers will compare blood tests and MRI scans from 100 patients with these conditions. The goal is to see i…

This study aims to better understand severe breathing problems in children arriving at a hospital emergency room in Egypt. Researchers will observe 70 children, from infants to teenagers, to learn how common these cases are, what causes them, and which factors put children at ris…

This study aims to understand if sudden kidney injury makes it harder for critically ill adults to be successfully taken off mechanical ventilators. Researchers will observe 85 patients in intensive care to see if kidney problems independently predict a more difficult or failed w…

This study aims to understand why some people have memory and thinking problems after a stroke, even after successful emergency clot removal. Researchers will follow 120 adult stroke patients for six months, tracking their recovery, mood, and brain function. The goal is to identi…

This study aims to make a common clubfoot surgery safer for infants. Researchers will use ultrasound to carefully measure the distance between the Achilles tendon and important nearby blood vessels and nerves in babies' feet. The goal is to gather detailed information that helps …

This study aims to see if two simple ratios calculated from routine blood tests can help tell breast cancer patients apart from healthy people. Researchers will look back at medical records of 110 people, comparing those with newly diagnosed breast cancer to healthy controls. The…

This study will compare two common types of IV lines used to give medicine and nutrition to newborns in intensive care. Researchers will follow 360 babies to see which line type has fewer infections, lasts longer, and causes fewer complications. The goal is to gather information …

This study aims to understand how common a specific, sometimes inherited, form of Down syndrome is among children in Assiut, Egypt. Researchers will test 230 children with confirmed Down syndrome and their parents to see if the parents carry a specific genetic rearrangement. The …

This study aims to understand if the types of bacteria in a person's gut affect how well their heart recovers after a severe heart attack and a stent procedure. Researchers will observe 144 patients who have had a heart attack, measuring a specific gut-related substance in their …

This study aims to understand what causes intussusception in adults, a rare condition where one part of the intestine slides into another. Researchers will follow 35 adult patients at Assiut University Hospital to determine whether benign or cancerous growths are more common, and…

This study aims to find the best way to measure activity on PET/CT scans in cancer patients. It will compare different calculation methods to see which one gives the most reliable results, particularly for patients who are obese. The goal is to help doctors interpret these import…

This study aims to understand if a class of diabetes medications called SGLT2 inhibitors can improve early signs of heart strain in people with type 2 diabetes. Researchers will use detailed heart ultrasound scans to measure changes in the left atrium (a heart chamber) in 100 par…

This study aims to better understand childhood asthma by observing how other health conditions affect it and by measuring specific substances in the blood. Researchers will follow 82 children, aged 6 to 12, who have asthma. The main goal is to see if these blood markers can help …

This study aims to find out how many people with a common type of fatty liver disease (MAFLD) also have high levels of uric acid in their blood. Researchers will screen 200 adult patients to measure this connection. The goal is to see if checking for and managing high uric acid c…

This study aims to find out if high levels of uric acid in the blood can serve as an early warning sign for faster kidney function decline in adults with prediabetes. Researchers will observe 150 adults with prediabetes and healthy kidney function to see if those with high uric a…

This study aims to understand if people with a specific cause of gastrointestinal bleeding (angiodysplasia) also have underlying blood clotting disorders. Researchers will enroll 55 adults with this condition to check their blood for specific factors. The goal is to see if these …

This study aims to see if having anemia (low red blood cells) can help predict how severe inflammatory bowel disease (IBD) will be and how often patients might need to go to the hospital. Researchers will follow 83 adult patients with IBD at an Egyptian hospital to see if their a…

This study aims to understand how Wilson's disease affects children's hormone systems. Researchers will examine 30 children with the condition to see if it causes problems with growth, puberty, or fertility. The goal is to identify these hidden complications so doctors can provid…

This study aims to understand if having a Helicobacter pylori (H. pylori) stomach infection is linked to more severe lupus symptoms. Researchers will observe 115 adults with lupus, checking for the infection and measuring their disease activity. The goal is to gather knowledge ab…

This study aims to understand the connection between vitamin D levels and insulin resistance in people with type 2 diabetes. Researchers will measure vitamin D and a specific marker of insulin resistance in 165 participants. The goal is to gather knowledge about this relationship…

This study aims to better understand prediabetes in young adults by observing how it relates to other health issues like high cholesterol and fatty liver. Researchers will collect health data from 120 adults with prediabetes at a single hospital. The goal is to identify patterns …

This study aims to see how well infants with cow's milk protein allergy or other feeding problems grow when they are given a special amino acid-based formula. Researchers will follow 160 infants for 6 months, measuring their weight, length, and head circumference each month. The …

This study aims to understand if high levels of a specific blood fat called Lipoprotein(a) are linked to more calcium buildup in the heart's arteries, as seen on a special CT scan. Researchers will enroll 150 adults at intermediate risk for heart disease who are already scheduled…

This study aims to find the best and safest way to begin a common type of minimally invasive gynecologic surgery (laparoscopy) in women who have scars from previous abdominal surgeries, like a C-section. Researchers will compare two different needle insertion techniques to see wh…

This study aims to compare two scoring systems (STUMBL and TTSS) that help predict complications and death in patients with blunt chest injuries from falls or accidents. Researchers will enroll 124 adult patients to see which scoring system works better for identifying high-risk …

This study aims to understand the causes and short-term outcomes for patients experiencing rectal bleeding (haematochezia) at Al-Rajhi University Hospital. Researchers will observe 70 adult patients over one year to identify common causes and factors that predict severe outcomes.…

This study aims to understand if there is a connection between vitamin D levels and a blood disorder called Immune Thrombocytopenia (ITP). Researchers will measure vitamin D in 84 adults who are newly diagnosed with ITP and have just started their first treatment. The goal is to …

This study aims to understand if the amount of a specific protein (METTL-14) found in endometrial cancer tissue is connected to how the disease behaves and how patients fare over time. Researchers will analyze tissue samples from 50 patients who have already been treated for a co…

This study aims to understand how blood clotting changes in adults newly diagnosed with a fast-growing blood cancer called acute myeloid leukemia (AML). Researchers will observe 80 patients, checking their blood's ability to clot before and after they receive a standard, strong c…

This study aims to understand why Candida fungal infections are hard to treat in very sick patients. Researchers will collect samples from 300 patients in a specialized intensive care unit to compare different types of Candida. They will look for how the fungus builds protective …

This study aims to understand how radiation treatment for abdominal cancers affects healthy liver tissue over time. Researchers will analyze existing CT scans from 70 patients before and after radiation therapy to measure changes in liver volume. The goal is to gather information…

This study aims to see if special eye scans can detect early signs of retinal damage in people with diabetes who have no vision problems. Researchers will compare scans from 112 participants—half with diabetes and half without—to look for subtle changes. The goal is to improve ea…

This study aims to understand how a common class of leukemia drugs, called tyrosine kinase inhibitors (TKIs), affects thyroid function. Researchers will monitor thyroid hormone levels in 76 adults newly diagnosed with a specific type of chronic leukemia who are starting this trea…

This study aims to understand how often and what types of blood vessel injuries happen when children break their elbow. Researchers will observe 50 children under 15 with this specific fracture to see which treatments work best and identify what factors increase the risk of a blo…

This study aims to find out how common and how severe thinking and memory problems are in people after they have had a stroke. Researchers will evaluate 400 stroke survivors to measure the prevalence of these cognitive issues. The goal is to better understand this often-overlooke…

This study aims to understand if a simple blood marker, calculated from triglyceride and glucose levels, is linked to small blood vessel complications in people with type 2 diabetes. It will observe 200 adults with the condition, tracking their standard lab results and health ove…

This study aims to understand how hormone levels are affected in children with simple obesity. Researchers will measure hormones in 67 children and teens aged 5-18 who have obesity not caused by other medical conditions. The goal is to gather knowledge about how excess weight imp…

This study aims to understand how being nearsighted or farsighted changes the physical structure of the eye's optic nerve and retina. Researchers will use a special imaging scan (OCT) to measure these structures in 266 adults with different vision prescriptions. The goal is to ga…

This study looks back at 10 years of medical records to understand how doctors at one hospital have treated a dangerous pregnancy condition called placenta accreta. Researchers will examine 300 cases where the placenta attaches too deeply to the uterus, which can cause severe ble…

This study aims to better understand the patterns seen on PET-CT scans in older adults (age 60+) with lymphoma. Researchers will analyze scans from about 63 patients to see if specific scan features can help doctors diagnose the disease more accurately and predict outcomes. The g…

This study aims to understand how often and what types of heart defects occur in children under two years old who have cholestasis, a condition where bile flow from the liver is reduced. It will also check how these children are growing and developing physically and mentally. The…

This study looks back at the medical records of 200 women treated for gynecological cancers at Assiut University Hospital between 2022 and 2025. The goal is to understand their survival rates and see how they compare to international standards. Researchers will analyze past treat…

This study aims to understand the characteristics and patterns of acquired aplastic anemia, a rare and serious blood disorder, in children from a specific region in Egypt. Researchers will review the medical records of 35 children diagnosed between 2020 and 2026 to document their…

This study aims to see if certain patterns in routine blood tests can help predict how patients with myelodysplastic syndromes (MDS) will fare. Researchers will look back at the medical records of 100 adults with MDS to check if scores based on blood protein and cell levels are l…

This study aims to understand if a specific ratio of 'bad' to 'good' cholesterol is linked to kidney damage in people with diabetes. Researchers will compare cholesterol levels in 84 adults with diabetes, some with and some without kidney problems. The goal is to gather knowledge…

This study aims to find out how common and what types of electrolyte imbalances occur in infants and young children who are hospitalized with stomach or intestinal diseases. Researchers will observe 150 children, aged one month to four years, who are admitted with these condition…

This study aims to better understand how childbirth affects women's pelvic floor muscles using safe, non-invasive ultrasound scans. Researchers will compare 185 women who had vaginal deliveries with those who had C-sections to see how these different birth methods impact pelvic s…

This study aims to understand how a common, often symptomless thyroid condition affects liver health and cholesterol levels. Researchers will compare 120 adults with this mild thyroid issue to healthy adults, measuring their liver enzymes and blood fats. The goal is to gather kno…

This study aims to find out how often a type of fatty liver disease (MASLD) develops for the first time in people after they receive a liver transplant. Researchers will enroll 100 adult liver transplant recipients to measure how common this is and identify the risk factors, like…

This study aims to measure how common violence is against women who are seeking treatment for infertility in Egypt. Researchers will survey 233 married women aged 18-45 to understand the link between infertility and abuse. The goal is to gather information to help address this se…

This study aims to see if a special type of heart ultrasound, called speckle tracking echocardiography, can detect very early heart changes in people with inflammatory bowel disease (IBD) before any symptoms appear. Researchers will enroll 100 adults with IBD to compare this adva…

This study aims to understand if the physical size and angle of the Eustachian tube (the small tube that drains the middle ear) is related to the pressure inside the ear. Researchers will use CT scans to measure these tubes in 50 healthy participants over age 7. The goal is to ga…

This study aims to find out how often a major type of stroke, caused by a large blockage in a brain artery, occurs at a hospital in Egypt. Researchers will observe 300 stroke patients over a year, collecting their medical and scan data. The goal is to understand how common these …

This study aims to understand how common a specific type of scar tissue on the retina (an epiretinal membrane) is in people who have diabetic eye disease. Researchers will observe 225 adult patients with both conditions to measure how often they occur together and identify what o…

This study aims to see if simple, low-cost blood tests can help predict how severe a heart attack is and who is at higher risk for complications, especially in patients with diabetes. Researchers will compare blood markers in 1,000 patients who have had a severe heart attack and …

This study aims to understand how belly fat measurements relate to heart disease risk in people with type 2 diabetes. Researchers will calculate 10-year heart risk scores for 238 adult patients and see how these scores connect with simple belly fat measurements. The goal is to fi…

This study aims to understand if exposure to the toxic metal lead is connected to the development or severity of multiple sclerosis (MS). Researchers will compare 140 people with MS to healthy individuals, measuring lead levels in their blood and looking at related biological mar…

This study aims to understand how often children with sickle cell disease experience painful episodes called vaso-occlusive crises and what complications result from them. Researchers will look back at the medical records of 25 children, aged 1 to 18, who have been hospitalized f…

This study aims to find out how common lactose intolerance is among adults with a specific type of irritable bowel syndrome (IBS) that causes chronic diarrhea. Researchers will test 70 patients using a genetic (PCR) test and a symptom questionnaire. The goal is to understand if l…

This study aims to identify which bacteria are present in serious neck infections and see how they relate to how well patients recover. Researchers will analyze samples from 50 patients to understand which antibiotics work best against these germs. The goal is to gather informati…

This study aims to see if a more detailed 3D measurement from CT scans can better show how well treatments are working for liver cancer. It will involve 66 adults with liver cancer who are not eligible for surgery and are receiving specific non-surgical treatments. The goal is to…

This study aims to see if a non-invasive device that uses stickers on the chest (the ICON® monitor) is a reliable and useful tool for tracking heart function in COPD patients who are critically ill in the intensive care unit. Researchers will observe 96 patients to see how well t…

This study aims to identify which premature babies are most at risk of needing a breathing tube when non-invasive breathing support fails. Researchers will look at the medical records of 160 very small, premature babies born before 32 weeks. The goal is to help doctors spot probl…

This study aims to understand how often liver cancer ruptures in patients at a specific hospital. Researchers will look back at medical records from the last five years to identify what factors make a rupture more likely and to see how patients fare one year after this serious co…

This study aims to understand if the amount of fluids a patient receives or loses in the first two days of intensive care is linked to developing sudden kidney injury. Researchers will closely monitor 120 critically ill adults who do not have kidney problems when they enter the I…

This study aims to learn more about a specific type of bacteria called Providencia that can cause urinary tract infections (UTIs). Researchers will collect samples from 241 patients with UTIs in Egypt to see how common this bacteria is, which antibiotics can fight it, and what ma…

This study aims to help doctors better predict how many eggs can be collected during IVF treatment. It will look at women undergoing a specific fertility procedure (ICSI) and measure the size and number of their ovarian follicles just before egg retrieval. The goal is to create a…

This study aims to learn if a substance in the blood called IL-33 is linked to lupus activity, especially kidney damage. Researchers will compare IL-33 levels in 150 people: lupus patients with kidney problems, lupus patients without kidney problems, and healthy individuals. The …

This study aims to understand how early stroke care—from symptom recognition to hospital arrival—affects patient recovery. Researchers will observe 125 stroke patients to track their awareness of symptoms, emergency response choices, and transportation methods. The goal is to ide…

This study aims to find out how common heavy menstrual bleeding is among female university students in Egypt. Researchers will survey students and check their blood to understand the problem's scale. The goal is to see how these heavy periods affect students' health, daily life, …

This study aims to understand how common anxiety and depression are among medical students and interns at Assiut University. Researchers will survey about 289 students to identify what factors might increase their risk and how mental health relates to their academic performance. …

This study aims to see if a simple ratio from two standard blood tests (C-reactive protein and albumin) can help doctors predict which patients with acute pancreatitis are at high risk for developing sudden kidney injury. Researchers will enroll 150 adult patients hospitalized fo…

This study aims to understand if changes in a patient's blood sugar levels before they receive antibiotics can help doctors predict how severe their sepsis will become. Researchers will monitor 105 adults in the ICU with sepsis, tracking their blood sugar and a new combined stres…

This study aims to test and compare new scoring systems designed to predict complications and survival in hospitalized patients with advanced liver cirrhosis (liver scarring). Researchers will enroll 100 adults admitted to the hospital with a serious complication of their liver d…

This study aims to understand how congenital heart disease affects growth in young children. Researchers will review medical records of 72 children aged 1 month to 2 years with heart conditions, comparing their weight, height, and head measurements to healthy growth standards. Th…

This study aims to understand how common violence is among women who come to the hospital with physical injuries in Egypt. Researchers will examine 160 adult women with trauma injuries to identify patterns and assess how well their medical-legal reports are documented. The goal i…

This study aims to find out how common ADHD symptoms are in children who also have epilepsy. Researchers will follow 185 children to identify possible risk factors for developing ADHD in this group and see how it might affect their epilepsy. The goal is to gather knowledge to hel…

This study aims to understand how thyroid and adrenal hormone levels change in ICU patients with septic shock, a severe and often fatal condition. Researchers will measure these hormone levels in 200 patients to see how they relate to the severity of the illness. The goal is to g…

This study aims to understand the health needs of older adults living in a rural Egyptian village. Researchers will interview 330 people aged 60 and older about their health, diet, daily activities, and quality of life, and take basic measurements like weight and blood pressure. …

This study aims to find out how common a serious condition called Hemolytic Uremic Syndrome (HUS) is among children admitted to a specific hospital in Egypt. It will enroll up to 50 children under 18 who are diagnosed with HUS. The main goal is to gather information on how many c…

This study aims to understand what the general public in Upper Egypt knows about H. pylori, a common stomach bacteria that can cause ulcers and other problems. Researchers will survey 500 non-medical adults to learn about their awareness, attitudes, and the challenges they face i…

This study aims to understand how feelings of alienation—like being disconnected or isolated—affect the mental health, social life, and overall quality of life of medical students at Assiut University. It will involve 77 students who are from other regions or countries. The goal …

This study aims to understand why some patients who need regular blood transfusions develop harmful immune reactions against the donor blood. Researchers will compare 100 patients with beta thalassemia or similar conditions, looking for a specific genetic marker (microRNA-155) th…

This study aims to understand the knowledge, attitudes, and habits of pregnant women in Egypt regarding self-medication. Researchers will survey about 420 women in their third trimester to learn how common self-medication is, what types of medicines are used, and why. The goal is…

This study aims to see if adding a measure of frailty (a state of reduced physical resilience) to standard risk scores can better predict serious bleeding in older patients hospitalized for a heart attack. It will enroll 850 patients over 65 years old. The goal is to gather knowl…

This study aims to see if a special heart ultrasound measurement, called left atrial strain, can help predict which heart attack patients might develop serious complications while still in the hospital. Researchers will observe 135 patients who have just had a major heart attack …

This study aims to understand how diabetes affects menstrual cycles in teenage girls and identify what factors might increase the risk of irregular periods. Researchers will compare 110 girls with diabetes to girls without diabetes, tracking their menstrual patterns over time. Th…

This study aims to understand if having obstructive sleep apnea (OSA) increases a person's risk for high blood pressure in the lungs, known as pulmonary hypertension. Researchers will observe 55 adults already diagnosed with sleep apnea, using heart ultrasound scans to measure lu…

This study is testing a new tool to help researchers use artificial intelligence (AI) more ethically in scientific studies. Researchers with AI experience will complete a survey to evaluate how well the tool addresses ethical concerns like data bias, transparency, and privacy. Th…

This study aims to understand what parents know about diaper rash and how they care for it. Researchers will survey 240 parents of children up to age 2 who are being treated for diaper rash at a specific hospital. The goal is to link parent knowledge and care habits with the type…

This study aims to see if two simple blood measurements—platelet size and an inflammation index—can help doctors better diagnose heart attacks and predict which patients are at higher risk for complications. Researchers will enroll 300 adults who arrive at the hospital with sympt…

This study aims to understand the patterns of microbial keratitis, a serious eye infection that can threaten vision, in patients at Assiut University Hospital in Egypt. Researchers will observe 100 patients to identify what germs cause the infections, what risk factors are involv…

This study aims to understand if children with brain conditions like seizures or migraines also have hidden heart problems. Researchers will use heart scans (echocardiograms) and EKGs on 70 children to look for connections. The goal is to gather knowledge to improve future care b…

This study aims to identify early warning signs that a child's epilepsy won't respond to standard medications. Researchers will examine medical records, brain scans, and test results from 200 children with epilepsy. The goal is to help doctors spot resistant cases sooner and cons…

This study aims to better understand how a specific hip ligament functions in children with developmental hip dysplasia (DDH), a condition where the hip joint doesn't form properly. Researchers will examine 50 children whose previous non-surgical and simple surgical treatments fa…

This study aims to understand if the thickness of a specific eye muscle affects how well surgery corrects crossed eyes (esotropia). Researchers will measure the muscle in 28 patients before they undergo a standard surgical procedure. The goal is to gather knowledge that could hel…

This study aims to understand which children with a rare brain inflammation called ADEM might have a harder time recovering. Researchers will look at early brain scans and spinal fluid from 32 children to see if certain patterns can predict their neurological health six months la…

This study aims to understand how nighttime blood pressure patterns affect the heart's electrical activity and pumping function in people with high blood pressure. Researchers will observe 140 adults with hypertension, measuring their blood pressure over 24 hours and performing h…

This study aims to understand if having a crooked nasal septum (deviated septum) affects the size of your sinuses and makes you more likely to get sinus infections. Researchers will analyze existing CT scans from 120 adults to measure sinus volumes and look for signs of infection…

This study aims to understand how the time between a major heart attack and treatment affects the heart's electrical patterns. Researchers will measure these patterns in 500 patients and see if they can predict serious complications during the hospital stay and in the six months …

This study aims to understand how obesity affects acid reflux disease (GERD). Researchers will examine 200 adults with obesity to see how common GERD is in this group and explore the connection. This is an observational study that measures and observes, not a treatment trial.

This study aims to see if a simple calculation based on two common blood tests (triglycerides and glucose) can predict insulin resistance in people with early-stage kidney disease who are also at risk for diabetes. Researchers will enroll 60 adults without diabetes to test this m…

This study aims to understand if having many seizures when epilepsy is first diagnosed makes it harder to control seizures in the long run. Researchers will look back at the medical records of 100 patients with newly diagnosed epilepsy. They will analyze if the number of early se…

This study aims to understand the connection between zinc levels in the blood and lupus nephritis, a serious kidney complication of lupus. Researchers will measure zinc in 75 people with lupus nephritis to see how common low zinc is and if it relates to standard kidney health mar…

This study aims to better understand von Willebrand disease (VWD), a common inherited bleeding disorder, in children in Upper Egypt. Researchers will observe 25 children with suspected or confirmed VWD to learn how often it occurs, what symptoms they experience, and how doctors c…

This study aims to see if doctors can predict the type of chest surgery a patient will need for a severe complication of pneumonia called a parapneumonic effusion. Researchers will enroll 95 adults who need surgery and check if a pre-surgery risk score and ultrasound results can …

This study aims to understand how often thyroid problems, abnormal cholesterol, and high uric acid occur together in adults who receive regular dialysis. Researchers will check these levels in 100 patients to see how they might be connected and relate to other health factors. The…

This study aims to check if three existing heart failure risk calculators, developed mainly in Western countries, work accurately for patients in Egypt. Researchers will follow 140 Egyptian heart failure patients for one year to see how well these calculators predict death and ho…

This study aims to understand if a substance in the blood called catestatin is linked to heart and blood vessel problems in people with systemic sclerosis (scleroderma). Researchers will measure catestatin levels in 70 patients and compare them to healthy people, looking for conn…

This study aims to find out if an infection called Helicobacter pylori (H. pylori) is linked to women having multiple miscarriages where the cause is unknown. Researchers will compare 50 women with a history of recurrent miscarriage to 50 women without that history, testing both …

This study aims to understand how standard leukemia drugs (called tyrosine kinase inhibitors) affect blood sugar and cholesterol levels in patients. It will observe 75 people with chronic myeloid leukemia who are not diabetic. The goal is to gather information about potential met…

This study aims to find better ways to spot early kidney damage in people with type 2 diabetes. Researchers will compare several markers of inflammation in the blood to see which ones best predict kidney problems. The goal is to help doctors identify and monitor patients at risk …

Aims of this study are to compare the effectiveness of dexmedetomidine versus fentanyl-midazolam in attenuating hemodynamic stress response during laparoscopic cholecystectomy (mainly HR). And to assess the recovery profile, the pain and opioid requirements, the sedation profile,…