Assiut University

This study investigates whether a single dose of a GnRH agonist (triptorelin) given alongside standard progesterone can improve pregnancy outcomes in women undergoing frozen embryo transfer cycles. The trial includes women aged 20-39 with good quality embryos and normal uterine l…

This trial compares two surgical approaches for tennis elbow that has not improved after at least six months of non-surgical treatments like rest or physical therapy. One group receives keyhole (arthroscopic) surgery, while the other receives traditional open surgery. The main go…

This study will look at 90 women who choose the etonogestrel implant (Implanon-NXT) for birth control after giving birth. Half will get the implant within 72 hours of delivery, and the other half will get it 4-6 weeks later. Researchers will track side effects, bleeding patterns,…

This study tests whether taking a low dose of the antibiotic azithromycin every day for a year can reduce the number of serious lung infection flare-ups in adults with non-CF bronchiectasis. About 500 participants will receive either azithromycin or a placebo pill, added to their…

This trial compares two ways of aligning the knee during a bone-cutting surgery (high tibial osteotomy) for people with knee arthritis and bow legs. One method aims for natural knee motion (kinematic), the other for straight leg alignment (mechanical). The study will track 100 ad…

This study tests a surgery called selective dorsal rhizotomy to reduce severe muscle stiffness (spasticity) caused by traumatic brain or spinal cord injury. The surgery involves cutting specific nerve rootlets in the spine to relax overactive muscles. Researchers will enroll 32 p…

This study will compare two surgical techniques for children who have repeated kneecap dislocations. One surgery repairs only the main ligament (MPFL), while the other also repairs a secondary ligament (MPTL). The goal is to see which approach better prevents future dislocations …

This study compares two ways to treat a common elbow fracture in children (Gartland type II). Half the children will get a cast after the bone is set, and the other half will have surgery with pins. Researchers will measure how well the arm works, how much it can move, and pain l…

This trial compares two latest-generation heart valves (SAPIEN 3 Ultra Resilia and Evolut FX) in 200 patients with severe aortic stenosis. Participants will be randomly assigned to receive one valve during a standard procedure and followed for one year. The goal is to see which v…

This study will test whether sildenafil, a drug often used for erectile dysfunction, can improve heart function in children aged 1-18 with dilated cardiomyopathy, a condition where the heart is enlarged and weak. Researchers will measure changes in the heart's pumping ability ove…

This study tests whether a single injection of nanofat (processed fat from your own body) can treat pattern hair loss better than standard options. Sixty adults with androgenetic alopecia will receive either one nanofat injection, three monthly PRP injections, or daily topical mi…

This study will test whether a special endoscopic (scope-based) surgery can completely remove tumors in difficult areas of the nose and sinuses. About 25 adults with these tumors will take part. Researchers will measure how often the tumor is fully removed, how much blood is lost…

This trial compares two surgical procedures for children aged 5 to 10 with relapsed clubfoot and a specific foot deformity called metatarsal adductus. One surgery involves cutting and realigning the midfoot bones, followed by 6 weeks in a cast. The other uses a small plate to gui…

This study tests a procedure called woundsome revascularization in 50 people with chronic limb-threatening ischemia (CLTI), the most severe form of peripheral artery disease. Doctors use balloon angioplasty to open blocked arteries that supply blood directly to the wound area. Th…

This study will follow 95 adults with moderate-to-severe Crohn's disease or ulcerative colitis in Upper Egypt who are taking one of five biologic drugs: adalimumab, infliximab, ustekinumab, golimumab, or vedolizumab. After one year, researchers will measure how many patients avoi…

This lab study tests whether chitosan nanoparticles—made from shrimp shells—can break down the sticky biofilms that protect E. coli bacteria in urinary tract infections. Researchers will collect bacteria from 60 patients and treat them with chitosan alone or with the antibiotic c…

This study tests a new way to guide fluid treatment in patients with septic shock (a severe infection causing low blood pressure). The goal is to see if using a non-invasive arm cuff to measure blood flow pressure can help doctors give the right amount of fluids to prevent acute …

This study compares two types of cartilage grafts used to repair eardrum holes in adults. One graft is thin (0.5 mm) and the other is thick (1.8 mm). The goal is to see which one leads to better healing and hearing after six months. Thirty adults with long-standing eardrum perfor…

This study tests a surgical technique to cover deep wounds on the lower leg, ankle, heel, or foot. The procedure moves skin and tissue from the outer lower leg to the wound area, using a special blood supply to help it heal. The study will include 30 adults and will measure how w…

This study compares two treatment lengths for children who have taken too much acetaminophen (paracetamol). One group gets the standard 21-hour treatment with N-acetylcysteine, and the other gets a shorter 12-hour version. Researchers will check liver function and side effects to…

This study tests whether giving more radioactive iodine can help people with differentiated thyroid cancer whose tumor marker (thyroglobulin) is high but whose scans show nothing. One hundred adults who have already had their thyroid removed and one round of radioactive iodine wi…

This study tests whether taking tranexamic acid pills along with a microneedling procedure that delivers glutathione into the skin works better for melasma than either treatment alone. Forty-two women with facial melasma will be split into groups to compare the approaches. The ma…

This study tests a new cream made with tiny nanoparticles of the drug apremilast for people with mild to moderate plaque psoriasis. Thirty-six adults will apply the cream twice daily for 12 weeks, and researchers will compare it to a standard steroid cream and a combination of bo…

This study compares two surgical devices used in neck fusion surgery for cervical degenerative disc disease. One device is a cage with built-in screws, the other is a traditional cage without screws. The goal is to see which leads to better bone fusion and fewer complications. Fo…

This pilot study will test a new surgical technique called Active Apex Correction (APC) in 15 children under 10 with early onset scoliosis. The procedure aims to straighten the spine by placing screws only on the outer side of the curve, avoiding cuts to the spine bones. Research…

This study tests whether injecting chemotherapy directly into a pancreatic tumor using an endoscope (EUS-guided) plus standard chemo works better than standard chemo alone. About 20 adults with locally advanced pancreatic cancer will take part. The goal is to see if the combinati…

This study looks at two methods of giving beta-lactam antibiotics to patients with sepsis or septic shock in the ICU: a slow 4-hour infusion versus a quick 30-minute infusion. Researchers will track survival at 90 days and whether the infection clears within 14 days. The goal is …

This early-stage trial will test whether a cream containing ivermectin (a drug used for parasites) can treat common skin warts. It will compare ivermectin alone, ivermectin combined with microneedling (tiny needles to help the cream absorb), and a standard salicylic acid treatmen…

This study looks at a new surgical technique to repair deep cuts in finger tendons without using a splint afterward. Forty adults will have the surgery and start moving their fingers gently right away. The goal is to see if this approach leads to better hand movement and strength…

This study tests a surgical procedure that uses the ligamentum teres, a natural ligament in the hip, to help stabilize the joint in children with developmental hip dysplasia (DDH). The surgery involves creating a tunnel in the bone and threading the ligament through it to improve…

This study tests a structured emergency plan called the MINUTES bundle for adults with undifferentiated circulatory shock (low blood pressure and poor organ perfusion). The bundle includes continuous monitoring, IV fluids, early blood pressure medication, bedside ultrasound, lab …

This study will test two supplements — essential phospholipid and betaine HCL/L-glutamic acid — in 200 adults with metabolic fatty liver disease (MAFLD). The goal is to see which one reduces fat in the liver more effectively. Participants will be followed for a period to measure …

This study tests a surgery called lunocapitate fusion for people with SNAC wrist, a painful condition caused by an untreated scaphoid fracture. The surgery aims to reduce pain and improve wrist function by fusing two wrist bones. Researchers will follow 35 adults for 12 months to…

This study looks at the long-term results of a surgery that replaces the missing growth plate at the top of the thigh bone in children who lost it due to a severe hip infection. Researchers will check how well the bone heals and how well the hip works at least five years after th…

This study tests a minimally invasive laparoscopic procedure to drain pyogenic liver abscesses in 30 adults who cannot have standard drainage. The goal is to see if it leads to fewer complications, faster recovery, and lower recurrence compared to open surgery or needle drainage.

This study looks at whether using both a nail and a plate together can better fix certain complex hip fractures. The approach is meant to prevent the bone from collapsing and help people heal faster. Seventeen adults with these fractures will be followed for six months to check b…

This phase 3 trial tests whether taking the antibiotic moxifloxacin for 7 days every 8 weeks (for a year) can reduce lung infection flare-ups in people with non-cystic fibrosis bronchiectasis. 140 adults who have had at least two flare-ups in the past year will be randomly assign…

This study will compare two methods of closing the skin after open appendix surgery: standard interrupted stitches versus a continuous stitch under the skin plus a small drain. The goal is to see which method leads to fewer wound infections and better healing. About 100 people ag…

This study tests a simple surgery where a piece of the patient's own vein is wrapped around a repaired nerve to reduce scarring and pain. It includes 43 adults aged 18-60 with nerve injuries below the elbow that need repair within 6 months. The goal is to see if this technique pr…

This study tests whether giving magnesium sulfate early through an IV can reduce dangerous narrowing of brain arteries after a traumatic brain bleed. About 50 adults with head injuries will receive the treatment within 24 hours. The goal is to see if it lowers the risk of delayed…

This study tests a drug called romiplostim, given as a weekly shot, in 100 children aged 1 to 18 with chronic immune thrombocytopenia (ITP) who haven't been helped by standard treatments. The goal is to see if it can safely raise platelet counts and reduce bleeding. Children will…

This study tests a minimally invasive procedure that uses heat (radiofrequency or microwave) to destroy abnormal growths in the abdominal wall, such as cancer spread, desmoid tumors, or endometriosis. It involves 30 people who cannot have surgery or choose not to. The goal is to …

This study tests whether virtual reality (VR) therapy works better than standard balance exercises for people with long-term dizziness. Researchers will enroll 40 adults aged 18-70 who have had dizziness for over 3 months due to inner ear problems. Participants will receive eithe…

This study tests a behavioral program called contingency management for people with opioid use disorder. Participants in an inpatient unit receive small rewards when they provide drug-free urine samples. The goal is to see if this approach helps them stay abstinent during their t…

This study tests whether using a BiPAP breathing machine at home can help people with severe COPD who have high carbon dioxide levels. Forty adults will use the machine nightly for a year while continuing standard medications. Researchers will track blood gas levels, breathing sy…

This study compares two common procedures—flexible ureteroscopy (a scope through the urinary tract) and shock wave lithotripsy (sound waves to break stones)—for treating small kidney stones (≤15 mm) located in the lower calyx. Researchers will enroll 70 adults and check which met…

This study tests a cream called terbinafine hydrochloride for treating fungal ear infections (otomycosis). About 50 adults with symptoms like itching, pain, and discharge will have the cream applied in the ear every two days for two weeks. The goal is to see if the cream clears b…

This study tests a shorter, higher-dose radiation schedule (3.5 Gy per fraction for 17 sessions) for people with early-stage glottic cancer (T1-T2N0M0). The goal is to see if this approach controls the tumor as well as standard longer radiation, while being more convenient. About…

This study tests a 12-week pulmonary rehabilitation program for people with stable COPD. The program includes hospital sessions (education, exercise, nutrition advice, smoking cessation) and home exercises (walking, strength training). Researchers will measure how far participant…

This study compares two heart failure medications—sacubitril/valsartan (a newer combo drug) and captopril (an older drug)—in 70 children aged 1 month to 18 years with dilated cardiomyopathy (an enlarged, weak heart). The goal is to see which drug better improves the heart's pumpi…

This study looks at whether common diabetes drugs called SGLT2 inhibitors (like empagliflozin and dapagliflozin) can improve the structure and function of the heart's left atrium in people with type 2 diabetes. Researchers will use advanced ultrasound to measure heart changes in …

This study tests whether giving a rectal dose of misoprostol before a planned C-section, on top of the usual oxytocin, can reduce blood loss during and after surgery. About 282 women having elective C-sections will be randomly assigned to receive either standard care or standard …

This phase 2 trial tests a dose-dense (faster) schedule of two chemotherapy drugs, gemcitabine and cisplatin, given before surgery for muscle-invasive bladder cancer. The goal is to see if this approach can completely eliminate the tumor in the bladder and lymph nodes. Thirty eli…

This study compares two types of back surgery for people with narrowing of the spine in the neck (cervical stenosis). The goal is to see which surgery better improves nerve function and quality of life. Only 2 adults aged 40 and older who need surgery will take part, and they wil…

This study compares two surgical techniques for infants born with choanal atresia, a condition where the nasal passages are blocked. Thirty infants up to 6 years old will receive either a puncture with mitomycin C or a flap technique. The goal is to see which method keeps the air…

This study tests whether breathing in a sedative called dexmedetomidine before anesthesia can prevent sudden blood pressure rises during emergency C-sections in women with severe preeclampsia. One hundred participants will be randomly assigned to receive either the drug or a plac…

This study looks at whether the drug sacubitril/valsartan (Entresto) can improve the heart's ability to relax in people with heart failure and reduced pumping strength. Researchers will use ultrasound to measure changes after six months of treatment. The study involves 70 adults …

This study looks at whether a 12-week cardiac rehabilitation program—including supervised exercise, education, and lifestyle advice—can improve heart function and quality of life in people who have had a heart attack treated with stenting. One hundred participants will be randoml…

This study explores whether routine blood tests—like CBC and lactate levels—can help doctors diagnose sepsis in newborns more quickly than waiting 2-3 days for a blood culture. Researchers will enroll 80 infants in the NICU with signs of infection and compare these rapid test res…

Rheumatoid arthritis and gout can look alike, making them hard to tell apart early. This study will use ultrasound to see if it can reliably distinguish between the two conditions. Researchers will examine 100 adults with suspected or confirmed arthritis, scoring joint inflammati…

This study looks at whether a substance in urine, called PGE-MUM, can show if ulcerative colitis is active or in remission. Researchers will collect urine and blood samples from 114 adults with confirmed ulcerative colitis and compare the results with colonoscopy findings. If suc…

This study will check if a new physical exam called Said's test can accurately diagnose biceps tendon injuries in the shoulder. Researchers will test 144 adults, including those with shoulder injuries and healthy volunteers. Two doctors will perform the new test and standard test…

Pleural effusion is excess fluid around the lungs, and doctors need to know if it's caused by body-wide issues (like heart failure) or local problems (like infection). The usual test requires a needle to draw fluid, which carries risks. This study will check if a simple chest ult…

This study will compare two types of scans—PET/CT and CT—to see which is better at finding distant spread of breast cancer. About 97 patients with advanced breast cancer will receive both scans within a few weeks. The goal is to improve early staging and guide treatment to improv…

This study will check how accurate chest X-rays are at finding congenital heart disease in newborns. Researchers will study 60 babies in the NICU who show signs of heart problems. Each baby gets a chest X-ray within 24 hours and an echocardiogram within 72 hours. By comparing the…

This study looks at whether measuring anti-alpha-actinin antibodies in the blood can help identify active lupus nephritis (kidney inflammation) in people with lupus. Researchers will compare antibody levels with findings from standard kidney biopsies in 96 adults. If the blood te…

This study looks at whether ultrasound can accurately check if bones are healing properly after Ilizarov surgery, a procedure that uses a metal frame to fix or lengthen bones. Researchers will compare ultrasound results with standard X-rays and physical exams in 56 patients. If s…

This study looks at whether non-invasive tests like blood counts and spleen size can accurately predict the presence and severity of enlarged veins in the esophagus (varices) in children with portal hypertension. Researchers will compare these simple markers to the standard metho…

This study will compare a newer imaging method called 18F-PSMA PET/CT with the standard CT scan for prostate cancer patients. The goal is to see if the new scan is better at finding cancer initially, checking how well treatment is working, and detecting cancer that has come back.…

This study looks at whether a detailed MRI of the blood vessel wall can help doctors tell the difference between two common causes of stroke: hardening of the arteries (plaque buildup) and inflammation of the vessel wall (vasculitis). About 46 people who recently had a stroke wil…

This study will check how well a non-invasive scan (FibroScan with CAP) measures liver fat compared to the standard liver biopsy in 100 living liver donors. The goal is to see if the scan can accurately assess donor liver health without the risks of a biopsy. Participants must be…

This study will test whether a type of MRI called arterial spin labelling (ASL) can accurately determine if a child's brain tumor is low-grade or high-grade before surgery. Researchers will compare the MRI results with the actual tumor grade found after surgery. The study plans t…

This study will compare two methods—triphasic CT scans and endoscopic ultrasound-guided biopsies—to see which one more accurately tells benign from malignant pancreatic lesions. Researchers will enroll 50 adults with pancreatic lesions found on initial imaging. The goal is to det…

This study aims to see if measuring two proteins in the blood, Talin-1 and Cripto-1, can help diagnose colorectal cancer. Researchers will compare these levels in 70 newly diagnosed patients and healthy people. The goal is to find a simpler, more accurate way to detect the diseas…

This study will test whether a special ultrasound technique called elastography can help doctors tell the difference between harmless and cancerous growths in the chest and digestive tract. About 35 adults will get an endoscopic ultrasound with elastography, and the results will …

This study explores whether measuring two specific genes (NEAT1 and ANRIL) in blood samples can help diagnose inflammatory bowel disease (IBD) without needing a colonoscopy. Researchers will test blood from 62 newly diagnosed IBD patients and look for links between these genes an…

This study tests a new way to detect fetal anemia using ultrasound. The new method measures the time it takes for blood to speed up in a brain artery, which may show anemia earlier than the current standard. The study will include 20 fetuses with anemia or high blood flow, and wi…

This study will test whether using multiple ultrasound techniques together can more accurately tell if a thickening in the upper digestive tract wall is cancerous or not. About 43 adults with unclear findings from standard scans will undergo a special endoscopic ultrasound proced…

This study tests whether combining standard MRI with two advanced techniques—MRI volumetry and diffusion tensor imaging—can more accurately identify the seizure-causing brain area in people with temporal lobe epilepsy. Researchers will compare these imaging results with clinical …

This study will check if standard mammogram and ultrasound images can accurately predict the molecular subtype of breast cancer. Researchers will compare imaging features to lab results from biopsies in 122 women with suspected or confirmed breast cancer. If imaging can reliably …

This study will test whether adding a T2 mapping sequence to a standard MRI can improve detection of early knee osteoarthritis. Researchers will compare MRI scans from 28 healthy volunteers and 28 patients with early OA. The goal is to see if this extra scan can measure cartilage…

This study looks at how well nerve tests and ultrasound can detect diabetic peripheral neuropathy, a common complication of diabetes that causes pain and numbness in the feet. Researchers will compare results from 75 adults with diabetes and healthy volunteers to see which tests …

This study will test whether a procedure called high-resolution anorectal manometry can help doctors figure out why some children have severe constipation that doesn't get better with standard treatments. The researchers will measure muscle and nerve function in the rectum and an…

This study will check if two simple blood test ratios (AST/ALT and MPV/platelet count) are different in women with breast cancer compared to healthy women. Researchers will look at medical records of 110 women to see if these ratios can help diagnose breast cancer. The goal is to…

This study will test a new scoring system called STAR, which combines a bedside ultrasound and simple blood tests, to predict internal belly injuries in adults who have suffered blunt trauma (like from a car crash or fall). Researchers will enroll 129 adults aged 18-60 who arrive…

This study looks at whether the triglyceride-glucose (TyG) index, a simple measure from a blood test, can predict insulin resistance in people with pre-diabetes and chronic kidney disease. Researchers will enroll 60 adults with and without kidney problems to see how well the TyG …

This study will check if an Arabic version of the SAMANTA questionnaire can reliably identify heavy menstrual bleeding in women aged 15 to 45. Heavy periods can cause anemia and harm quality of life, but simple screening tools are lacking. Researchers will enroll 120 women to tes…

This study tests a new, less invasive biopsy method for uterine masses. The procedure uses a thin needle guided by ultrasound through the cervix to take a tissue sample. Researchers want to see if it can accurately tell benign from malignant growths, potentially helping women avo…

This study tests whether a 10-minute cardiotocography (CTG) test can accurately check fetal well-being during labor, compared to the standard 30-minute test. Researchers will enroll 200 low-risk pregnant women in active labor at a hospital in Egypt. If the shorter test works well…

This study will test whether a special MRI technique called T1 mapping can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The goal is to see if this non-invasive scan can replace the need for a heart biopsy. The study plans to enroll 40 …

This study looks at how CT scans can help doctors identify heart and blood vessel problems in children with Tetralogy of Fallot, a serious heart condition present at birth. About 37 children up to 12 years old will get a CT scan to find hidden issues and help plan surgery. The go…

This study tests whether a special ultrasound can find complications like re-rupture or infection in the first 6-12 weeks after hand tendon repair. Fifty adults who had tendon surgery will get ultrasound scans, and doctors will compare the results to standard follow-up methods. I…

This study will check how useful endoscopy is for finding the cause of stomach and gut issues in 150 children from birth to 18 years old at Assiut University Children Hospital. The goal is to see how often the procedure gives a clear diagnosis and to track any risks. The results …

This study tests whether a simple bedside ultrasound of the inferior vena cava can detect low blood volume in shock patients as accurately as the standard invasive central venous pressure monitoring. Researchers will enroll 80 adults with shock from blood loss, infection, or othe…

This study will test whether detailed 2D and 3D ultrasound scans can accurately tell the difference between two serious pregnancy complications: placenta accreta spectrum and uterine scar dehiscence. Researchers will scan 50 women in their third trimester who have a low-lying pla…

This study looks at whether a substance in the blood called sCD163 can help doctors find HELLP syndrome early in pregnant women. HELLP is a rare but serious condition that can harm the liver and blood. Researchers will compare sCD163 levels in 70 pregnant women—some with HELLP an…

This study tests whether the BIND score, a quick neurological check, can predict brain risk in newborns with severe jaundice. Researchers will use the score to guide phototherapy treatment in 80 infants under 28 days old. The goal is to catch and treat dangerous jaundice early, p…

This study will screen 35 adults with scleroderma for pulmonary hypertension using echocardiography. The goal is to see how often this serious lung condition occurs in these patients. The study is not yet recruiting.

This study will test a special ultrasound technique called shear-wave elastography to see if it can better detect tendon inflammation (enthesitis) in people with psoriatic arthritis. Researchers will compare this method with standard ultrasound and also look at how it relates to …

This study will check how well a non-contrast CT scan (CT KUB) can tell harmless kidney cysts from suspicious ones, using the Bosniak classification system. About 200 people with kidney cysts found on CT will also get an ultrasound for comparison. The goal is to see if this commo…

This study will examine 100 children aged 6 to 18 who have had chronic abdominal pain for at least 3 months. Doctors will perform an upper endoscopy (a camera down the throat) to see how often it finds abnormalities in the stomach or intestines. The goal is to understand if this …

This study looks at whether two blood markers – mean platelet volume (MPV) and the systemic inflammatory response index (SIRI) – can help diagnose and predict outcomes in people with acute coronary syndrome (heart attack or unstable angina). Researchers will measure these markers…

This study will test whether artificial intelligence can accurately tell the difference between inflammatory arthritis (like rheumatoid arthritis) and degenerative arthritis (like osteoarthritis) in people aged 60 and older. Researchers will compare the AI's analysis of X-rays, M…

This study tests whether applying vancomycin powder directly into the surgical wound during shunt placement can prevent infections in children with hydrocephalus. About 164 children will be randomly assigned to receive either standard care or standard care plus the powder. The go…

This study tests whether giving anti-epileptic drugs right after a traumatic brain injury can prevent seizures. About 70 adults with moderate to severe head injuries will receive either the drug or standard care. Researchers will track seizure episodes and recovery over 3 months …

This study will test two different surgical techniques used during heart bypass surgery to see which one better prevents a common complication called atrial fibrillation (irregular heartbeat). The trial will involve 122 adults having their first planned bypass surgery. Researcher…

This study compares two drugs, ketamine and fentanyl, added to a standard numbing medicine (bupivacaine) to control pain after laparoscopic gallbladder removal. 84 adults aged 20-50 will receive one of the two combinations during surgery. The goal is to see which provides longer-…

This study tests two ways of giving tranexamic acid, a drug that helps blood clot, to adults who are coughing up blood. One group breathes the medicine in through a mask (nebulizer), while the other gets it through an IV. The goal is to see which method stops the bleeding within …

This study compares two ways to perform total hip replacement: the standard direct lateral approach and a newer, less invasive method called SuperPATH. Researchers want to see if SuperPATH reduces pain, blood loss, and recovery time while improving joint stability. 100 adults nee…

This study looks at whether changing body position and doing special breathing exercises can help prevent lung issues like pneumonia after heart surgery. About 124 adults having planned heart surgery will be split into four groups: one getting usual care, one doing only breathing…

This study compares two types of nerve blocks (thoracolumbar interfascial plane block and retrolaminar block) to see which one helps patients recover better after lumbar spine fusion surgery. 70 adults scheduled for surgery will receive one of the two blocks before the procedure.…

This study will compare two medicines, dexmedetomidine and lidocaine, given through a vein to help place a breathing tube (laryngeal mask) in 60 children aged 2-12 having elective surgery. The goal is to see which drug leads to a successful first attempt, fewer tries, and less co…

This trial will compare two techniques for removing kidney stones larger than 2 cm: a flexible suction sheath (FANS) and direct suction through the scope (DISS). About 100 adults will be randomly assigned to one method. The study will measure surgery time, how completely stones a…

This study looks at whether adding a suture tape during ACL reconstruction helps patients recover faster. 114 people aged 15-50 with an ACL tear will be split into two groups: one gets standard surgery, the other gets surgery plus tape. Both groups will follow an accelerated reha…

This study tests a new treatment for burn scars on the chest, shoulders, and back. Doctors will take a small amount of fat from the patient's belly or thigh, process it into a liquid rich in healing cells, and inject it into the scar. The goal is to improve the scar's look, feel,…

This study tests if transferring a person's own belly fat to the penis can safely and effectively increase its thickness. 25 men who are unhappy with their size and have a flaccid girth under 11 cm will receive the procedure. Researchers will measure changes in circumference and …

This study compares two gels—hyaluronic acid gel and petroleum jelly—to see which works better for stopping nosebleeds. About 50 people with nosebleeds that start in the front of the nose will be treated with one of the gels. The main goal is to see which gel stops bleeding faste…

This study compares two common back surgeries for people with lumbar spinal stenosis (a narrowing of the spine that presses on nerves). One surgery only removes the pressing bone and tissue, while the other also adds metal screws and rods to stabilize the spine. Researchers will …

This study compares a plant-based gel (B-sitosterol) to plain Vaseline for treating frequent, unexplained nosebleeds. About 162 people who have had at least two nosebleeds in the past month will apply one of the two gels inside their nose for a period. The goal is to see which on…

This study compares two treatments for keloids (raised scars that grow beyond the original wound). One group gets a special freezing treatment inside the scar (intralesional cryosurgery) alone. The other group gets the same freezing plus an injection of two medicines (5-fluoroura…

This study compares three ways to treat facial acne scars: injecting nanofat (a processed form of your own fat) alone, or combined with either platelet-rich fibrin (a blood concentrate) or microneedling. About 42 adults with moderate to severe scars will receive treatment on both…

This study tests a new topical gel containing 5% spironolactone against a standard 0.1% adapalene gel for treating acne. Forty people with mild to moderate acne will apply each gel to opposite sides of their face, allowing direct comparison. The goal is to see if the spironolacto…

This study tests whether taking a daily 5 mg tadalafil pill can help men with an enlarged prostate recover bladder control faster after surgery. About 40 men will receive either tadalafil or a placebo for 12 weeks after their procedure. The goal is to see if the drug reduces stre…

This study tests if inflating a small balloon in the stomach during surgery can prevent nausea, vomiting, and slow stomach emptying after pancreatic tumor removal. About 70 adults will be randomly assigned to get the balloon procedure or standard surgery. Researchers will track r…

This study compares two treatments for arm stiffness after stroke: a combination of phenol injections for large muscles plus botox for smaller muscles, versus botox alone. Sixty adults who had a stroke at least six months ago will take part. The goal is to see if the combined app…

This study looks at a surgery called calcaneal osteotomy for adults with severe plantar fasciosis that hasn't improved with other treatments. The surgery aims to reduce tension on the plantar fascia without cutting it. Researchers will measure pain and foot function in 11 partici…

This study compares two drug combinations—dexmedetomidine versus fentanyl plus midazolam—to see which better controls stress on the heart during laparoscopic gallbladder removal. Fifty adults aged 18-65 will be enrolled. The goal is to find a safer, more stable anesthesia approac…

This study will test whether a gel containing dutasteride, a drug usually used for hair loss, can treat facial acne. Fifty adults with acne will apply the dutasteride gel to one side of their face and either a placebo or a standard triple-combination acne gel to the other side. R…

This study will test whether a sodium bicarbonate enema can help relieve constipation and reduce harmful waste products in people with chronic kidney disease (CKD). The researchers believe the gut can act as an extra filter to remove toxins that build up when kidneys fail. They p…

This study compares two minimally invasive treatments for chronic plantar fasciitis (heel pain): pulsed radiofrequency ablation and steroid injections. It will enroll 122 adults aged 18-65 with chronic plantar fasciitis. The goal is to see which method provides better pain relief…

This study compares two medicines, dexmedetomidine and ketamine, added to a standard painkiller (bupivacaine) given through a caudal block to control pain after hip surgery in children aged 1 to 6 years. The goal is to see which combination provides better pain relief, lasts long…

This study tests whether adding ketamine to a standard painkiller (bupivacaine) and rinsing the surgical area during gallbladder removal can better control pain after surgery. Sixty adults having laparoscopic gallbladder removal will be randomly assigned to receive either the sta…

This study looks at whether giving a combination of anti-nausea drugs before surgery can help prevent the nausea and vomiting that often happens after gallbladder removal. The trial will involve 102 women who are having this surgery. Researchers will compare two different drug co…

This study tests whether injecting platelet-rich plasma (PRP) into the vocal cords can help people with vocal fold sulcus, scar, or atrophy. Researchers will measure voice quality and patient well-being in 48 participants over a follow-up period. The procedure is done under local…

This study compares two types of nerve blocks (ESPB and QLB) to see which provides better pain relief for children aged 2-12 after kidney surgery. One hundred children will be randomly assigned to receive one of the two blocks. The main goal is to see how long it takes before the…

This pilot study will test if low-intensity shockwave therapy can safely improve blood flow and ease symptoms in 30 men with erectile dysfunction caused by blood vessel problems. Participants will receive treatment using a special device and be monitored for side effects and chan…

This study looks at two ways to close the skin after children have surgery to reverse a stoma. One method uses a purse-string stitch, and the other uses a straight line closure. The goal is to see which method leads to fewer infections and better-looking scars. About 50 children …

This study tests two different medicines added to standard spinal anesthesia for hip surgery. The goal is to see which one provides better pain relief and faster recovery. About 92 adults having hip surgery will take part. The results could help doctors choose the best option for…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce symptoms of ADHD and autism in children and teens aged 6-19. Participants will receive either real or sham (fake) stimulation over three weeks. The goal is to see if it is safe and if it im…

This study compares two surgical techniques for fusing bones in the lower back: using two straight cages or one curved (banana-shaped) cage. The goal is to see which method provides better pain relief, faster recovery, and fewer complications. About 30 adults with chronic back pa…

This study compares early task-oriented rehabilitation (practicing daily-life activities) to traditional physiotherapy in 158 adults who had a stroke within the past 48 hours. The goal is to see which approach leads to better motor function and quality of life after 3 months. Par…

This study tests whether using a combination of lidocaine, dexmedetomidine, and magnesium instead of opioids can control pain and reduce nausea after gallbladder removal. 110 adults having elective laparoscopic cholecystectomy will be randomly assigned to opioid-free or standard …

This study tests two common sedatives, dexmedetomidine and midazolam, to see which better prevents shivering in trauma patients having lower leg surgery under spinal anesthesia. Shivering affects up to 60% of these patients and can cause discomfort and complications. The trial wi…

This study will compare two methods of giving N-acetylcysteine—a drug that thins mucus—to 70 adults hospitalized with bronchiectasis. Half will receive the drug through a nebulizer (inhaled), and half through an IV. Researchers will measure how well each method reduces sputum thi…

This study compares two different lengths of time (6 weeks vs. 12 weeks) that children wear a hip cast after surgery for a dislocated hip (DDH). The goal is to see if a shorter cast time works just as well for healing and movement, with fewer problems like skin sores. About 40 ch…

This study tests whether injecting a larger or smaller amount of fluid around the median nerve in the wrist better relieves pain from carpal tunnel syndrome. 35 adults with mild to moderate carpal tunnel will receive either 8 ml or 3 ml of dextrose, or a steroid injection. The go…

This study looks at a procedure called POEM for people with achalasia, a condition where the esophagus has trouble moving food to the stomach. It compares patients getting POEM as their first treatment versus those who had a previous balloon dilation that didn't work well. Resear…

This study compares two medicines, dexmedetomidine and nalbuphine, added to a standard numbing drug (bupivacaine) for a nerve block in the armpit area. The goal is to see which combination provides longer pain relief after upper arm surgery. 66 adults scheduled for elective arm s…

This study will check if caffeine, already used to treat breathing pauses in premature babies, also helps keep their heart rate and blood pressure steady. Researchers will monitor 40 preterm infants in the NICU before and after caffeine treatment. The goal is to see if caffeine i…

This study compares two tools used during thyroid removal surgery: LigaSure and bipolar diathermy. The goal is to see which one leads to shorter surgery time, less pain, and fewer complications. Thirty adults having partial or total thyroid removal will take part.

This study will compare two anesthesia methods—total intravenous anesthesia (TIVA) and inhalational anesthesia—to see which better prevents nausea and vomiting after laparoscopic obstetric surgery. About 98 women aged 18-50 undergoing elective laparoscopic procedures will be rand…

This study tests whether propofol or lidocaine, given right after surgery, can reduce agitation when children wake up from tonsillectomy. Eighty-two children aged 4 to 7 will be randomly assigned to receive one of the two drugs. The goal is to find a safer, more comfortable recov…

This study tests whether placing a small drain to let out leftover gas after gynecologic laparoscopy can reduce shoulder pain. The gas can irritate the diaphragm and cause pain in the shoulder. 124 women having laparoscopy lasting over 20 minutes will be randomly assigned to get …

This study tests whether adding dexmedetomidine to the standard numbing drug bupivacaine in a specific nerve block can reduce opioid painkiller use and pain intensity after upper abdominal cancer surgery. About 54 adults aged 18-70 scheduled for surgeries like gastrectomy or hepa…

This study will compare different surgical techniques for treating severe gynecomastia (enlarged male breasts) in 45 men aged 18-60. The goal is to see which method gives the best cosmetic results and highest patient satisfaction. Participants will be randomly assigned to one of …

This study tests if a new combination of nerve blocks (suprascapular plus costoclavicular) with added clonidine can provide pain relief equal to the standard interscalene block after shoulder surgery, but with fewer breathing side effects. About 60 adults having elective shoulder…

This study compares two pain-relieving drugs, lidocaine and ketamine, given through an IV, to see if they can reduce stubborn face or mouth pain. About 105 adults with pain that hasn't responded to other treatments will receive one or both drugs. The goal is to measure pain relie…

This study tests whether injecting platelet-rich plasma (PRP) into the wound after fistulotomy surgery for simple anal fistula can speed healing and reduce pain. About 70 adults aged 18-65 with simple low anal fistulas will be randomly assigned to get either standard surgery plus…

This study will test a special recovery plan for 100 women having emergency C-sections after 34 weeks of pregnancy. The plan includes better pain control, early movement, and quick return to eating and drinking. Researchers will measure pain, how fast women can eat and walk again…

This study will test whether a superficial cervical plexus block, a numbing injection near certain neck nerves, can reduce pain after maxillofacial surgeries like abscess drainage or lymph node biopsies. Seventy adults aged 18-65 will be randomly assigned to receive the block or …

This study looks at whether placing children in a specific position when their breathing tube is removed after sleep apnea surgery can reduce the risk of dangerously low oxygen levels. About 262 children aged 2-10 will take part. The goal is to find a simple, no-cost way to make …

This study compares two medications, dexmedetomidine and fentanyl, given during general anesthesia for major abdominal cancer surgery. The goal is to see which drug better maintains heart function and stability. About 70 adults undergoing elective surgery will participate, and th…

This study compares two sedative drugs, dexmedetomidine and ketamine, given before spinal anesthesia for varicocele surgery. The goal is to see which one provides better sedation and fewer side effects. The trial will involve 58 men aged 18 to 40.

This study tests whether adding magnesium sulfate or lidocaine to a standard sedative (dexmedetomidine) better prevents coughing after functional endoscopic sinus surgery. Coughing after this surgery can cause bleeding and slow recovery. About 102 adults will be randomly assigned…

This study compares three approaches for treating atrophic acne scars: subcision alone, subcision plus fractional CO2 laser, and subcision plus platelet-rich plasma (PRP). Forty-two adults with mild to severe scars will receive treatment on different sides of the face to see whic…

This study looks at two types of surgery for people with severe hand or underarm sweating. The goal is to see if operating on one nerve (T3) instead of two (T3-4) can lower the chance of developing heavy sweating in other body areas after surgery. About 46 participants aged 6 and…

This study tests a new surgical technique to correct sagging breasts (ptosis) in 28 women. The procedure uses the patient's own breast tissue and fat grafting to lift and add fullness, avoiding foreign materials. The goal is to improve breast shape and patient satisfaction.

This study tests whether potassium citrate, a medication that makes urine less acidic, can relieve painful UTI symptoms in women aged 18-50. Fifty participants will take either potassium citrate or the antibiotic nitrofurantoin for 7 days. Researchers will compare symptom scores …

This study compares two types of nerve blocks—caudal block and sacral erector spinae plane block—both using a numbing medicine plus dexmedetomidine, to see which provides longer pain relief after hypospadias repair in boys aged 1-6. The goal is to improve comfort and reduce compl…

This study looks at whether it is safe to remove kidney stones right away in people whose kidneys are not working well due to the blockage. Normally, doctors place a temporary tube first to protect the kidney, but this adds extra procedures and visits. The trial will enroll 60 ad…

This Phase 3 study tests whether taking a low dose of two different erectile dysfunction drugs (tadalafil 2.5 mg plus sildenafil 25 mg) daily works better than taking a standard dose of just one (tadalafil 5 mg). The trial will involve 142 men aged 18 to 70 with ED for at least 3…

This study tests whether giving lidocaine through an IV during gallbladder surgery can reduce inflammation and pain, and help the gut start working again sooner. 90 adults having planned laparoscopic gallbladder removal will be randomly assigned to receive either lidocaine or a p…

This study looks at how obstructive sleep apnea (OSA) affects thinking skills like attention and memory, and how those changes relate to quality of life. Adults newly diagnosed with OSA will take an overnight sleep test, followed by computer tasks and questionnaires. Their result…

This study looks at blood flow in a part of the fetal heart called the aortic isthmus in pregnancies where the baby is not growing well (fetal growth restriction). Researchers will compare Doppler measurements between affected fetuses and healthy ones to see if these patterns can…

This study will look at 60 adults with a type of high blood pressure in the lungs (pre-capillary pulmonary hypertension) to see if measurements from a CT scan match those from a standard invasive heart catheter test. If the CT scan proves reliable, it could offer a safer, less in…

This observational study will use bedside ultrasound to measure the diaphragm—the main breathing muscle—in 120 adults with liver cirrhosis and compare them to healthy volunteers. Researchers want to see if cirrhosis weakens the diaphragm and if removing fluid from the belly impro…

This study looks at women with diminished ovarian reserve (DOR) — a condition where the ovaries have fewer eggs, making IVF harder. Researchers are examining specific RNA molecules in the fluid around eggs to see how they relate to egg quality and embryo development. The goal is …

This study looks at how common heart problems are in children with ADHD. Researchers will compare 50 children with ADHD who take medication to 50 healthy children. They will use ECG and echocardiograms to check for heart issues.

This study tests a new surgical method for removing the splenic flexure during laparoscopic surgery for left-sided colorectal cancer. It compares the new technique (inferior mesenteric artery first with complete medial approach) to traditional methods. The goal is to see if it is…

This study tests whether artificial intelligence can improve how medical interns counsel patients to quit smoking. 140 interns will receive either standard training or AI-assisted case-based training. Their counseling skills will be measured before and after using the 5A model (A…

This study will follow 210 women in Egypt who have either a planned (elective) or unplanned (emergency) C-section to compare complications like bleeding, infection, and newborn breathing problems. Researchers want to see if emergency C-sections truly carry higher risks for mother…

This study will measure a protein called IL-41 in the blood of 90 people with ankylosing spondylitis or psoriatic arthritis, plus healthy volunteers. Researchers want to see if higher levels of this protein are linked to more active disease. The goal is to find a simple blood tes…

This study will check 45 adults with ankylosing spondylitis for peripheral neuropathy (nerve damage in the arms and legs) using nerve conduction tests. Researchers want to see if nerve problems are linked to higher disease activity, increased pain sensitivity, and worse quality o…

This study follows 45 adults with alpha-1 antitrypsin deficiency (a genetic condition that can cause liver damage) to learn how the disease progresses. Researchers will analyze stored blood and liver tissue samples to find biomarkers and understand the molecular pathways involved…

This study aims to find out how often foot deformities like flatfoot or clubfoot occur in Egyptian adolescents aged 12 to 18. Researchers will examine 4,000 teens and look at factors like age, sex, and pain. The goal is to understand the types of deformities and how they affect d…

This study looks at whether a routine blood test (RDW) can help doctors quickly identify how well the heart and lungs are working together in people with a sudden lung clot (pulmonary embolism). Researchers will measure RDW and compare it to an ultrasound measure of heart-lung co…

This study will test whether special imaging scans (ICG lymphography and high-frequency ultrasound) can predict how well a surgery called lymphaticovenous anastomosis works for arm swelling after breast cancer treatment. Thirty women with mild to moderate lymphedema will be scann…

This study aims to find out how often thyroid problems occur in adults aged 60 and older at Assiut University hospitals. It will also look at how these thyroid issues are linked to other health conditions and the use of multiple medications. The results will help doctors better u…

This study will examine 30 adults with a specific type of meniscus tear in the knee (posterior horn medial meniscus root tear). Using MRI and arthroscopy, researchers will classify different tear patterns and see how they relate to cartilage damage and other knee problems. The go…

This study will check how often muscle loss (sarcopenia) happens in 120 adults with metabolic fatty liver disease. Researchers will also see if muscle loss is linked to more severe liver scarring. The goal is to better understand the connection, not to test a new treatment.

This study looks at the eating habits of 50 pregnant women with inflammatory bowel disease (IBD). Researchers want to see if better diet quality is linked to healthier pregnancies and baby growth. The goal is to find nutritional gaps and suggest better dietary advice for this gro…

This study tests a new way to estimate a baby's weight before birth using ultrasound. Instead of only measuring bones, it also measures soft tissue thickness in the belly and thigh. Researchers hope this will give more accurate weight predictions, especially for very large or ver…

This study checks if artificial intelligence (AI) can accurately predict how a person's nose will look after rhinoplasty (nose job) surgery. Researchers will compare AI-generated predictions with actual post-surgery photos using digital analysis. The study involves 20 adults sche…

This study looks at vitamin D levels in 63 critically ill children (ages 1 month to 12 years) admitted to the ICU with severe breathing infections. Researchers will measure vitamin D in the first 24 hours and compare it to how severe the infection is and the risk of death. The go…

This study will examine heart function in 80 newborns with sepsis using a special ultrasound (tissue Doppler echocardiography) and blood tests for cardiac troponin and other sepsis markers. The goal is to see if these tests can predict heart problems early. The study includes bot…

This study looks at whether a simple, non-invasive ultrasound can predict the risk of dangerous bleeding from enlarged veins in the esophagus (varices) in people with liver cirrhosis. Researchers will measure spleen size and a key blood vessel diameter on ultrasound and compare t…

This study will check how many people with knee osteoarthritis also have sarcopenia—a condition of low muscle mass and strength. Researchers in Upper Egypt will study 224 adults aged 40 and older to measure muscle health, nutrition, and quality of life. The goal is to better unde…

This study will look at a specific genetic marker called PCGEM1 in blood and tissue samples from 90 newly diagnosed breast cancer patients. The goal is to learn more about how breast cancer develops and find possible targets for new treatments. No extra procedures are needed beyo…

This study looks at whether teenagers aged 15-19 living in Beni Adi village, Egypt, have their rights met in four areas: health, education, protection (like no early marriage or violence), and community participation. Researchers will interview 300 teens to see what's working and…

This study will use ultrasound to check for tendon inflammation (tenosynovitis) in children with two types of juvenile idiopathic arthritis (JIA): polyarticular and oligoarticular. Researchers will examine 106 children under 16 at Assiut University Hospital, comparing physical ex…

This study will enroll 144 adults with acute coronary syndrome (heart attack or unstable angina) to see how inflammatory markers (hs-CRP and neutrophil-to-lymphocyte ratio) and cardiac troponin levels relate to heart function measured by echocardiography. Researchers hope to impr…

This study will test a new way to measure fetal heart function using ultrasound in 15 pregnant women whose babies have anemia. The goal is to see if this heart measure can help doctors decide when to treat the anemia. The study is not yet recruiting and is purely observational.

This study compares two ways of using a breathing machine during laparoscopic abdominal cancer surgery. Sixty adults aged 20-80 will be randomly assigned to one of two ventilation modes. Researchers will measure heart function and lung health to see which method is better.

This study looks at why fluid builds up around the lungs in people with advanced chronic kidney disease (CKD). Researchers will test 100 adults to see if standard diagnostic methods work well for these patients. The goal is to improve accuracy so doctors can treat the right cause…

This study will use a device called an indirect calorimeter to measure how much energy critically ill patients in the ICU actually burn. Researchers want to see if this method is more accurate than standard formulas for guiding nutrition. The goal is to improve nutritional suppor…

This study looks at 70 children and teens with juvenile lupus to check for early signs of heart disease using an ultrasound of the neck artery. Researchers will see if things like cholesterol, blood pressure, and lupus activity are linked to artery thickness. No treatment is give…

This study looks at the challenges and opportunities in providing healthcare to women who have survived gender-based violence in Upper Egypt. Researchers will talk to healthcare providers and survivors to understand what makes it hard to get good care. The goal is to create recom…

This study looks at whether a bedside lung ultrasound can help doctors see how well the lungs of obese patients are opening during a breathing machine procedure. The goal is to find the best air pressure to keep lungs open and improve oxygen levels. About 45 adults with a BMI of …

This study tests whether a heat stress awareness program can reduce heat-related illness symptoms in outdoor workers in Upper Egypt. Researchers will train 84 workers before the hot season and compare their health responses to a group that receives no training. The goal is to see…

This study aims to find what factors predict recovery in children with acute disseminated encephalomyelitis (ADEM), a rare brain condition. Researchers will follow 25 children aged 6 months to 18 years to see how many recover fully and how many have relapses. The study does not t…

This study will follow 46 people treated for stage III rectal cancer to see if PET-CT scans can help doctors make better treatment decisions during routine follow-up. Participants will already be getting these scans as part of their care and will be tracked for 5 years. The goal …

This study examines two microscopic details in bladder cancer tumors—how deep early cancer cells have invaded and whether small clusters of cells are present at the tumor's edge. Researchers will look at tissue samples from 100 patients to see if these features can predict if the…

This study will look back at the medical records of 150 children with retinoblastoma who received additional eye treatments after initial chemotherapy. The treatments include radioactive plaque therapy, freezing therapy, or laser therapy. The goal is to see how often each treatme…

This study looks back at medical records of 60 adults who had surgery for severe pelvic fractures. It compares the standard open surgery (large cut) with a newer minimally invasive method (small cuts) to see which leads to better healing, fewer complications, and faster return to…

This study looks at 30 adults on a heart-lung machine (ECMO) for severe heart failure. Researchers will measure brain oxygen levels and compare them to blood flow and other vital signs. The goal is to see if brain oxygen monitoring can help guide treatment and improve survival in…

This study will watch and record information from 120 newborns with serious gut problems admitted to the NICU. Researchers will track what types of emergencies are most common, how long babies stay in the hospital, and how many need surgery. The goal is to better understand these…

This study examines stored tumor samples from 100 bladder cancer patients who had their bladder removed. Researchers will measure the amount of supportive tissue, immune cells, and immune clusters near the tumor. The goal is to see if these features are linked to how long patient…

This study looks at whether having a baby soon after a previous C-section increases the chance of problems like heavy bleeding or organ injury during the next C-section. Researchers will follow 80 pregnant women with one prior C-section. The goal is to help women and doctors plan…

This study looks at whether dry eye disease makes it harder to calculate the right lens power for cataract surgery. Researchers will compare 100 patients with and without dry eye to see if those with dry eye have less accurate lens measurements. The goal is to find out if treatin…

This study aims to find early warning signs of acute kidney injury in children admitted to the intensive care unit. Researchers will monitor 100 children, tracking their medical history, daily fluid intake, urine output, and lab tests. The goal is to identify which risk factors—l…

This lab study looks at whether verapamil, a common blood pressure medicine, can make antibiotics work better against drug-resistant bacteria. Researchers will test bacteria samples from 100 cancer patients in Egypt. The goal is to find a cheap, new way to fight superbugs, but th…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will fill out pain and disability questionnaires and get a physical exam. The goal is to help doctors better understand and treat back pa…

This study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…

This study looks at whether certain blood test results (hs-CRP, triglycerides, and glucose) can help identify liver scarring in people with non-alcoholic fatty liver disease (NAFLD). Researchers will observe 96 adults who have NAFLD and check their blood markers alongside liver s…

This study looks at whether children who had surgery to close a large hole in their heart (called a VSD) will catch up in growth. Researchers will measure weight, height, and BMI before and after the procedure in 58 children aged 1 month to 2 years. The goal is to see how long it…

This study will measure levels of a small molecule called microRNA-155 in 100 people who need regular blood transfusions, mostly due to beta thalassemia. The goal is to see if higher levels of this molecule are linked to the formation of harmful antibodies against donated blood. …

This study looks at two immune-related proteins, CD274 and CD276, in people newly diagnosed with B-cell cancers like leukemia and lymphoma. Researchers will use a blood test to measure these proteins and see how they help cancer hide from the immune system. The goal is to find be…

This study will measure two immune proteins, IL-17A and IL-10, in the blood of 80 people newly diagnosed with B-cell acute lymphoblastic leukemia. Researchers want to see if these levels are linked to lab results and how well patients respond to treatment. The goal is to learn mo…

This study looks at 80 children aged 5 and older who wet the bed at least twice a week for three months. Researchers will use interviews, physical exams, urine tests, and ultrasounds to find underlying causes like constipation, infections, or enlarged tonsils. The goal is to bett…

This observational study will follow 50 patients with primary spondylodiscitis, a serious spinal infection, for one year. Researchers will track cure rates, pain levels, and daily function using standard treatments like antibiotics and braces. The goal is to understand how well c…

This study will look at how long-acting reversible contraception (LARC) affects quality of life in women aged 18 to 45. Researchers will compare women using LARC methods to those using other birth control. They will measure changes in physical health, mental well-being, social re…

This study looks at children with beta-thalassemia major, a genetic blood disorder requiring lifelong transfusions. Researchers will measure growth and check for risk factors like iron overload that may stunt development. No new treatment is given—just careful observation of 85 c…

This study will measure two immune system markers, CD305 and CD85d, on cancer cells from 180 people newly diagnosed with B-cell blood cancers. The goal is to see how these markers relate to different cancer types and patient outcomes. No treatment is given; the study only observe…

This study will check children under 18 with chronic liver disease for hidden heart problems. Doctors will use simple tests like ECG and ultrasound to look for issues such as abnormal heart rhythms or weakened heart muscle. The goal is to better understand how liver disease affec…

This study looks at how weight and body mass index (BMI) change in people with inflammatory bowel disease (IBD) who are treated with biologic drugs. Researchers will track weight monthly and see if higher BMI leads to higher drug doses and costs. The goal is to understand the fin…

This study will observe 65 children, aged 1 to 24 months, hospitalized with bronchiolitis at Assiut University Hospital. Researchers will collect information on family, social, and medical factors to identify what makes the illness more severe. The goal is to help doctors predict…

This study compares laparoscopic (keyhole) hysterectomy to traditional open abdominal hysterectomy in women aged 35-65 with benign gynecologic conditions. The main goal is to see which approach leads to a shorter hospital stay. The trial takes place in a low-resource setting, whe…

This study will observe 84 critically ill children with sepsis to understand how often heart injury occurs and what predicts it. Researchers will use blood tests and heart ultrasounds to track heart function. The goal is to better identify and manage heart problems in these child…

This study in Assiut, Egypt, will check 116 children aged 2-15 for intestinal parasites to see if these infections are more common in malnourished kids compared to healthy ones. The goal is to understand how parasites like Giardia and hookworms might cause or worsen malnutrition …

This study will check how common parasitic infections are in 285 people with blood disorders, like anemia or blood cancers, at Assiut University hospitals in Egypt. Researchers will test for Toxoplasma and other parasites. The goal is to understand if routine screening could help…

This observational study will follow 45 adults with severe plaque psoriasis to see how standard treatment affects their skin, dermoscopic images, and quality of life. Participants will be evaluated at the start and again after 12 and 24 weeks of treatment. The goal is to better u…

This study compares two different X-ray views—full-leg standing and Rosenberg—to measure a specific knee angle (MPTA) in 49 patients scheduled for high tibial osteotomy. The goal is to see if one view gives more consistent or accurate measurements, which could help surgeons bette…

This study will use safe, non-invasive 2D and 3D ultrasound to measure pelvic floor changes in 185 women who have given birth. Participants will fill out a short questionnaire and have a pelvic exam. The goal is to compare findings between women who delivered vaginally and those …

This study will watch 50 children under 15 with a specific elbow fracture to see how often blood vessel injuries happen and what factors make them more likely. Researchers will also look at how different treatments work. The goal is to better understand and manage these complicat…

This study looks at a simpler way to detect resistance to colistin, a last-resort antibiotic, in multidrug-resistant bacteria. Researchers will collect 90 samples from hospitalized patients and compare a disk test to the standard method. They will also check for resistance genes …

This study looks at how common muscle loss (sarcopenia) is in people with inflammatory bowel disease (IBD) using CT scans. Researchers want to see if muscle loss changes how well biologic treatments work. About 50 adults with IBD who have received biologic therapy will take part.

This study will look at 130 children with chronic abdominal pain to see how often an upper endoscopy (a camera down the throat) finds a physical cause. The children will have the procedure as part of their normal care, and researchers will analyze the results. The goal is to bett…

This study will check how well hospitals follow infection prevention steps before, during, and after C-sections. Researchers will track 105 women for 30 days after surgery to see if better adherence lowers infection rates. The goal is to improve maternal health and reduce surgica…

This study examines 80 samples of Pseudomonas aeruginosa bacteria that are resistant to multiple antibiotics. Researchers will measure the activity of a gene called mexB, which helps the bacteria pump out drugs, and check how much slime (biofilm) the bacteria produce. The goal is…

This study will check if a specific cholesterol ratio (non-HDL to HDL) is linked to kidney disease in people with diabetes. Researchers will measure this ratio and kidney function in 84 adults. The goal is to better understand risk factors, not to test a new treatment.

This study will observe 90 adults with anal fistulas to see if the time between first symptoms and surgery affects healing and recurrence. Participants are grouped by how long they waited: 3 months or less, 3 to 6 months, or more than 6 months. Researchers will track healing, rec…

This study will measure how many people in Assiut Governorate, Egypt, have schistosomiasis, a parasitic disease. Researchers will test urine and stool samples from 359 participants and ask about risk factors. The goal is to better understand the current burden of the disease in t…

This study looks at how acute kidney injury (AKI) impacts the process of removing a breathing tube (weaning) in critically ill adults in the ICU. Researchers will track 85 patients to see if AKI makes weaning harder, slower, or more risky. The goal is to learn whether kidney prob…

This study compares two common techniques for starting a laparoscopic procedure in people who have had previous abdominal or pelvic surgeries. One method uses a Veress needle to inflate the belly before inserting the camera, while the other inserts the camera directly. The goal i…

This study will follow 225 adults with end-stage kidney disease who are on regular dialysis. Researchers want to see if missing a dialysis session raises the risk of heart problems like heart attack or stroke within the next 72 hours. Participants will have heart tests after a mi…

This study will use ultrasound to measure the distance between the Achilles tendon and nearby nerves and blood vessels in both feet of 40 infants with unilateral clubfoot. By comparing the clubfoot to the normal foot, researchers hope to give surgeons better guidance to avoid acc…

This study will enroll 61 adults with sepsis in the ICU to see if certain blood-based inflammatory and nutritional markers (like NLR, PLR, PNI, and SII) can predict death and disease severity more accurately than established clinical scores like SOFA and APACHE. Researchers will …

This study looks at why some children are born with droopy eyelids (congenital ptosis). Researchers will examine the eyelid muscle during surgery and under a microscope to understand what goes wrong. The goal is to learn more about the muscle's development to help guide better su…

This study will survey 350 married women aged 18-49 in Assiut, Egypt to assess their knowledge, attitudes, and use of family planning methods. Researchers will also explore social and economic factors that influence contraceptive choices. The goal is to gather information that ca…

This study will check if low vitamin D levels are linked to higher insulin resistance in 165 adults with type 2 diabetes. Researchers will use a simple blood test called the triglyceride-glucose index. The goal is to better understand how vitamin D might affect diabetes control.

This study looks at whether combining a blood test for H. pylori bacteria with a painless stomach ultrasound can predict serious complications from peptic ulcers, like bleeding or a hole in the stomach. Researchers will study 230 adults with stomach symptoms to see if these non-i…

This study follows 62 people who need a second surgery for crossed or wandering eyes (strabismus). Researchers want to find out what factors increase the risk of needing repeat surgery and how successful the second operation is. Participants get a personalized surgical plan and a…

This study explores whether a simple ultrasound and a blood test can track celiac disease activity, potentially replacing the need for invasive intestinal biopsies. Researchers will scan the small bowel and measure antibody levels in 140 people, including newly diagnosed patients…

This study looks at 200 adults with fatty liver disease to find out how many are also obese. It will also describe the health details of patients who have fatty liver but are not overweight. The goal is to better understand the different types of fatty liver disease.

This study looks at 160 women (18+) who come to Assiut University Hospital with physical injuries. Researchers want to find out how many of these injuries are from violence and what patterns the injuries follow. They will also check how well doctors write forensic reports. The go…

This study will use ultrasound to measure blood flow in the brains of 200 healthy newborns, both full-term and premature. The goal is to find normal differences in brain blood flow based on how early a baby is born. These reference values could help doctors spot problems earlier …

This study will examine whether lead exposure is linked to multiple sclerosis (MS). Researchers will measure blood lead levels, oxidative stress markers, and epigenetic changes in 140 people with MS and healthy controls. The goal is to better understand how environmental factors …

This study looks at how well different methods—imaging, a small camera surgery (laparoscopy), and open surgery (laparotomy)—agree on whether an ovarian mass can be completely removed. It will involve 28 women with primary ovarian cancer. The goal is to see if less invasive method…

This study will follow 75 people with chronic myeloid leukemia who are taking tyrosine kinase inhibitors (imatinib or nilotinib). Researchers want to see if these drugs change blood sugar (HbA1c) and cholesterol levels. The goal is to understand side effects better, not to test a…

This study looks at how the size and number of ovarian follicles (fluid-filled sacs containing eggs) on the day of the trigger shot affect how many eggs are retrieved during an IVF cycle. Researchers will measure follicles using ultrasound in 60 women aged 18-35 undergoing ICSI. …

This study will look at how common von Willebrand disease is among children in Upper Egypt, what symptoms they have, and how they are treated. Researchers will review medical records and lab tests from 25 children aged 0-18 with suspected or confirmed VWD. The goal is to improve …

This study will compare obsessive-compulsive symptoms in 102 adults with substance use disorder to a similar group without it. Participants will complete interviews and questionnaires to measure OCD severity, addiction severity, and quality of life. The goal is to understand how …

This study looks at whether a short educational program can help teenagers in Assiut, Egypt, learn more about mental health, feel less stigma, and be more willing to seek help. About 150 students aged 13-18 will take part. The program includes three weekly sessions covering menta…

This study looks at stored tumor samples from 70 women with a common type of breast cancer (ER-positive, HER2-negative) who received hormone therapy. Researchers want to see if two specific proteins, p-AKT and p-S6, can help tell which cancers will respond to treatment and which …

This study will check if a protein called Tim-3 on certain white blood cells (neutrophils) is linked to disease activity in people with ankylosing spondylitis. Researchers will measure Tim-3 levels and compare them with inflammation markers and MRI scans of the hip and sacroiliac…

This study will follow 83 adults with inflammatory bowel disease (IBD) at Assiut University Hospitals in Egypt to see if anemia can predict worse outcomes like hospitalizations. Anemia is common in IBD, but its role as a predictor is not well studied in this population. Researche…

This study will review medical records of 72 children aged 1 month to 2 years with congenital heart disease (CHD) to see how their growth compares to healthy children. Researchers will measure weight, height, and head circumference. The goal is to understand which types of CHD af…

This study compares blood test results from 200 adults with type 2 diabetes to healthy people to see if platelet size and activity are different. Researchers will also check if these changes are linked to inflammation markers and blood sugar control. No treatments or extra proced…

This study will test a new scoring system (Mansoura score) to predict a serious bacterial infection called spontaneous bacterial peritonitis in people with liver cirrhosis and fluid buildup in the belly. Researchers will enroll 250 adults to see how well the score identifies who …

This study looks at how the shape and angle of the eustachian tube (the small canal connecting the middle ear to the throat) relate to pressure inside the middle ear. Researchers will use CT scans to measure these features in 50 healthy people aged 7 and older. The goal is to bet…

This study will measure levels of a thyroid antibody called anti-thyroglobulin in 112 adults with diabetes. The goal is to see how common these antibodies are in diabetic patients, since diabetes and autoimmune thyroid disease often occur together. Participants will provide a blo…

This study looks at how obesity influences treatment response in 120 adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will track whether obese patients respond differently to standard therapies, especially biologics. The …

This study will follow 120 critically ill adults in the ICU to see if the amount of fluid they receive in the first 48 hours is linked to developing acute kidney injury (AKI). Researchers will track fluids hourly and check kidney function for up to 7 days. The goal is to find pat…

This study is developing a tool to help researchers use artificial intelligence (AI) ethically in their work. AI is now used in many steps of research, from analyzing data to writing papers, but it can raise ethical concerns like bias or privacy. The study will ask 200 people who…

This study will follow 80 adults with newly diagnosed acute myeloid leukemia (AML) who are receiving intensive chemotherapy. The goal is to measure changes in blood clotting profiles before and after treatment. Researchers hope to better understand bleeding risks and improve care…

This study aims to find out if the number of seizures a child has when first diagnosed with epilepsy can predict how well their seizures will be controlled in the long run. Researchers will review medical records and interview 100 patients at Assiut University Children's Hospital…

This study looks at how feelings of alienation (feeling disconnected or estranged) affect the psychological and social health of medical students at Assiut University. Researchers will survey 77 students from outside Assiut or international students to measure their quality of li…

This study will check 200 adults with metabolic fatty liver disease for Helicobacter pylori infection using a stool test. The goal is to find out how common H. pylori is in this group. If a link is confirmed, it may open the door to new ways to manage fatty liver disease by treat…

This study looks at whether the ratio of C-reactive protein to albumin (CAR) in the blood can help predict acute kidney injury in people with acute pancreatitis. Researchers will measure CAR in 150 adults admitted to Assiut University Hospitals and see how it relates to kidney pr…

This study looks at whether a simple intestinal ultrasound can accurately measure disease activity in people with active ulcerative colitis, compared to the standard colonoscopy. Researchers will enroll 200 adults with active UC to see if the ultrasound scores match the colonosco…

This study will screen 200 adults with metabolic fatty liver disease (MAFLD) for high uric acid levels. Researchers will measure uric acid and liver function at diagnosis and after 6 months. The goal is to understand how common high uric acid is in these patients and whether it c…

This study will survey 500 non-medical adults in Upper Egypt to learn what they know about H. pylori infection, how it's diagnosed, and what barriers they face in getting care. Participants will fill out a simple questionnaire. The goal is to identify gaps in public understanding…

This study looks at how heart procedures change mental health in people with congenital heart disease. About 60 patients will complete surveys on mood, thinking, sleep, and eating before surgery, one month after, and three months after. The goal is to help doctors better screen a…

This study will look at 300 adults with acute ischemic stroke to find out how many have a large vessel occlusion (a big clot in a major brain artery). Researchers at Assiut University Hospitals will use CT or MRI scans to identify these patients and describe their characteristics…

This study will use CT scans to measure how the liver changes in size after radiation therapy. Researchers will look at scans taken before and after treatment in 70 adults with cancers near the liver. The goal is to better understand liver response to radiation and improve future…

This study aims to learn more about microbial keratitis, a serious eye infection, by examining 100 patients at Assiut University Hospital. Researchers will identify the germs causing the infection, look for risk factors, and track complications and outcomes. The goal is to improv…

This study will test 70 people with IBS-related diarrhea to see how many actually have lactose intolerance. Researchers will use a PCR test and a symptom questionnaire to find links with age and gender. The goal is to better understand if lactose intolerance is a common, overlook…

This study will check if certain blood cell measurements (platelet count, size, and shape) are linked to how active inflammatory bowel disease (IBD) is. Researchers will compare these blood test results with standard disease activity scores in 84 adults with IBD. The goal is to s…

This study will check how common thinking and memory problems are in people who have had their first stroke. Researchers will evaluate 400 adults aged 18 to 60 within three months of their stroke. The goal is to better understand the impact of stroke on the brain, not to test a n…

This study looks at whether measuring visceral fat (belly fat) using CT scans can predict how well ulcerative colitis patients respond to biologic therapy. Researchers will follow 200 adults with active ulcerative colitis for 6 months, tracking changes in fat volume and treatment…

This study will enroll 100 adults with septic shock to compare two non-invasive methods for measuring how well the heart is pumping blood: standard ultrasound (echocardiogram) and a newer device called electrical cardiometry, which uses sensors on the chest. The goal is to see if…

This study looks at whether adding a quick, painless ultrasound scan of the neck to a standard mouth exam can better predict if placing a breathing tube will be difficult. About 160 adults having planned surgery will be randomly assigned to either the standard exam alone or the s…

This study will enroll 70 pregnant women to test a new way of measuring amniotic fluid using ultrasound. The new method adds the size and shape of the baby's bladder to standard fluid measurements. Researchers hope this combined score will more accurately detect when fluid levels…

This study will look at 130 people with H. pylori-related gastritis to see if the infection is linked to anxiety, depression, or other psychological symptoms. Researchers will also check whether treating the infection improves mental health. The goal is to better understand the c…

This study will check if people with lupus nephritis have low zinc levels and how that relates to kidney function. Researchers will measure zinc, urea, creatinine, and other markers in 75 participants. The goal is to better understand the connection, not to test a treatment.

This study will follow 30 children under 18 who have surgery for a specific type of brain tumor (midline posterior fossa tumors). The goal is to see how well they recover and what factors affect their recovery and survival. The results may help doctors better predict outcomes and…

This study looks at whether levels of a protein called uromodulin in the blood can help predict how well kidneys recover in adults with sepsis-related acute kidney injury. Researchers will measure uromodulin at the start, after one week, and at hospital discharge in 30 patients. …

This study will use ultrasound to measure the length and volume of the liver in babies of mothers with gestational diabetes. Researchers want to see if these measurements can serve as early markers of how the mother's blood sugar levels affect the baby. The study will compare 115…

This study looks at different methods for measuring SUV (a key value in PET/CT scans) in 80 adult cancer patients. The goal is to see which correction method gives the most reliable results, especially for people with obesity. The findings could help doctors interpret scans more …

This study will examine how metabolic syndrome—a cluster of conditions like high blood pressure, high blood sugar, and excess belly fat—relates to gastroesophageal reflux disease (GERD). Researchers will enroll 50 adults with metabolic syndrome and use an endoscopy to check for s…

This study will compare 100 people with either multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD) to find better ways to tell them apart. Researchers will measure specific proteins in the blood and look at MRI scans. The goal is to improve diagnosis and man…

This study will look back at medical records of 100 people with a rare complication of liver cancer called rupture, where the tumor breaks open. Researchers want to find out how common this is, what raises the risk, and how long people live after it happens. The goal is to better…

This study will test 100 women with repeated miscarriage of unknown cause for H. pylori infection using a stool test. The goal is to see if the infection is more common in these women. If a link is found, it may lead to future research on screening or treatment.

This study will survey 233 married women aged 18-45 who are seeking infertility treatment in Egypt to find out how common violence is against them. Researchers want to understand if infertility makes women more likely to experience abuse. The goal is to use this information to be…

This study compares two types of temporary stomas (loop ileostomy and loop transverse colostomy) created after colorectal surgery to protect the bowel connection from leaking. About 36 adults having planned or emergency colorectal surgery will be randomly assigned to one stoma ty…

This study will check if an ultrasound scoring system called O-RADS can accurately tell benign from cancerous ovarian masses. About 80 women aged 18 to 70 with ovarian cysts or masses will get standard care, including detailed ultrasound and, if needed, surgery. Researchers will …

This study will follow 200 children with epilepsy to find clues—like brain scans or EEG patterns—that show which kids are likely to become resistant to standard seizure medications. The goal is to catch these cases early and consider alternative treatments such as a ketogenic die…

This study will survey 300 general practitioners in Upper Egypt to evaluate their knowledge, attitudes, and practices regarding Helicobacter pylori infection. Researchers aim to identify common barriers that prevent proper diagnosis and treatment. The goal is to highlight gaps th…

This study will follow 67 children hospitalized with pneumonia to find out which early signs—like breathing rate, oxygen levels, or blood tests—best predict a severe case. The goal is to help doctors spot high-risk children sooner and tailor their care. No new treatments are bein…

This study will enroll 70 adults with septic shock to compare two methods for deciding how much fluid to give: the standard central venous pressure (CVP) catheter and a non-invasive ultrasound that measures the inferior vena cava. Researchers want to see which method more accurat…

This observational study will enroll 135 adults who had a severe type of heart attack (STEMI) and were treated with angioplasty. Researchers will use a special ultrasound technique to measure left atrium strain within 48 hours of admission. The goal is to see if this measurement …

This study will survey 420 pregnant women in their third trimester in Assiut, Egypt, to understand their knowledge, attitudes, and practices around self-medication. Participants will answer a questionnaire about what medications they take, why, and where they get information. The…

This study compares two scoring systems (REDS and qSOFA) to see which better predicts death within 30 days for adults coming to the emergency room with suspected sepsis. Researchers will enroll 80 patients and track their outcomes. The goal is to find a more accurate tool to help…

This study looks at 300 adults hospitalized with heart failure to see if iron deficiency (with or without anemia) is linked to abnormal heart rhythms or ECG changes. Researchers will measure iron levels and monitor for arrhythmias like atrial fibrillation or ventricular tachycard…

This study will track 139 newborns who have seizures in their first month of life to learn how common these seizures are, what causes them, and how the babies fare during their hospital stay. Researchers will use exams, blood tests, and brain scans to gather information. The goal…

This study will ask 380 heart patients and healthcare workers at Assiut University Heart Hospital to fill out questionnaires about depression, anxiety, stress, and burnout. No treatments or changes are given—the goal is simply to find out how common these mental health problems a…

This study will compare blood test results and ultrasound images of joints in 72 people with rheumatoid arthritis. Half are taking JAK inhibitors, and half are on traditional treatments. The goal is to see if certain blood markers can reliably show how active the disease is, whic…

This study looks at two standard methods of stitching the kidney artery during a living donor kidney transplant: interrupted sutures and continuous sutures. Researchers will review past cases and follow 70 new adult patients at Assiut University to see which technique leads to sh…

This study will compare two methods (STUMBL and TTSS) for predicting serious complications and death in adults with blunt chest trauma, like from a car crash or fall. Researchers will enroll 124 patients to see which scoring system helps doctors make faster, better decisions in t…

This study aims to see if MRI can measure breast tumor volume more accurately than the usual one-dimensional ruler method. About 59 women with suspicious or confirmed breast cancer will get an MRI before surgery, and the MRI-based tumor volume will be compared to the actual tumor…

This study will check the health, nutrition, and daily living abilities of 330 older adults (age 60+) living in a rural village in Assiut, Egypt. Researchers will interview participants and take simple physical measurements like weight and blood pressure. No treatments are given—…

This study will examine PET-CT scan images from 63 patients aged 60 and older who have lymphoma. The goal is to describe the patterns and metabolic activity seen on the scans, which may help doctors better diagnose and predict the course of the disease. No new treatments are bein…

This study will look at 80 men with non-obstructive azoospermia (no sperm in semen due to poor sperm production) who are scheduled for bilateral microscopic testicular sperm extraction (micro-TESE). The goal is to see how often sperm can be successfully retrieved from a single te…

This study will observe 120 young adults with prediabetes to understand how different types of prediabetes relate to metabolic syndrome, a cluster of conditions that raise the risk for heart disease and diabetes. Researchers will classify participants based on blood sugar levels …

This study will measure vitamin D levels in 100 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) to see if low vitamin D is linked to more active disease. Participants will have blood tests for vitamin D and inflammation markers. The goal is to better unders…

This study looks at 100 men with varicoceles (enlarged veins in the scrotum) to see if the amount of backward blood flow affects sperm quality. Participants will have ultrasound and semen tests before and 3 months after varicocele repair surgery. The goal is to better understand …

This study looks at how well different veins collapse in people with severe injuries and low blood volume (shock). Researchers will use ultrasound to measure collapse of veins in the leg, neck, and belly before and after giving fluids. The goal is to see if these measurements can…

This study will look at the medical records of 35 children aged 1 to 18 who have acquired aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. Researchers want to learn about the symptoms, possible causes, and how the disease is managed in Assi…

This study will measure thyroid and adrenal hormone levels in 200 ICU patients with septic shock. The goal is to understand how these glands are affected during severe infection. No treatment is given; the study only observes and records hormone changes.

This study will look at Candida fungi from 300 patients in a hematology ICU. Researchers want to see how often these fungi form biofilms (slimy layers that protect them) and whether that makes them resistant to antifungal drugs. The goal is to learn which Candida types are most c…

This study will examine 106 infants under two years old who have cholestasis (a liver condition) to see how many also have congenital heart defects and how their development is affected. Researchers will use echocardiograms and developmental assessments. The goal is to better und…

This study will look at 225 adults with diabetic retinopathy to find out how many also develop an epiretinal membrane — a thin, scar-like layer on the retina that can blur vision. Researchers will use eye scans to detect the membrane and check for related factors like age, diabet…

This study will test new scoring systems to see how well they predict serious complications and death in 100 adults hospitalized with liver cirrhosis. Researchers will compare these new scores to standard ones to find which best identifies high-risk patients. The goal is to impro…

This study looks at the real-life challenges faced by people with Wilson's disease in Upper Egypt, a rare condition where copper builds up in the body. Researchers will survey 66 patients and their caregivers about diet, knowledge, attitudes, and barriers to care. The goal is to …

This study will look at 35 adults with a bowel condition called intussusception, where one part of the intestine slides into another. Researchers want to find out how often the cause is harmless (like a benign growth) versus serious (like cancer). They will also check how well im…

This study looks at how the length of the eye and the amount of nearsightedness or farsightedness relate to the health of the optic nerve and surrounding layers. Researchers will use a special camera (OCT) to take detailed images of the eye in 266 adults. The goal is to better un…

This study will check if two proteins found in spinal fluid (NSE and S100B) can help predict how well children with encephalitis (brain inflammation) will recover. Researchers will follow 90 children aged 1 month to 18 years who have symptoms like confusion, seizures, or fever. T…

This study will use a special eye scan called OCT to look for early signs of retinal damage in people with diabetes who have no vision problems. Researchers want to see if these scans can detect changes before symptoms appear. About 112 participants will get a detailed eye exam, …

This study will look at whether certain markers from a standard complete blood count (CBC) can help doctors assess how severe acute pancreatitis is and predict patient outcomes. Researchers will analyze data from 100 adult patients treated for acute pancreatitis. The goal is to s…

This study looks at whether a mild form of underactive thyroid (subclinical hypothyroidism) affects liver enzymes and cholesterol levels. Researchers will compare 120 adults with and without the condition. No treatment is given — the goal is simply to understand the connection be…

This study follows 120 adults who had a stroke and underwent a procedure to remove a blood clot from a large brain artery. Researchers will test their thinking and memory at 3 and 6 months after the procedure. The goal is to find out which patients are more likely to develop cogn…

This study will track blood sugar levels in 105 ICU patients with sepsis before and after they receive antibiotics. Researchers want to see if large glucose fluctuations or a 'glycemic shock index' can predict serious outcomes like kidney injury or death. The goal is to find a si…

This study looks back at the medical records of 200 people treated for gynecological cancers (like ovarian, cervical, or uterine cancer) at Assiut University Hospital between 2022 and 2025. The goal is to measure how long patients survive after diagnosis and compare those numbers…

This study will compare MRI scans with standard X-rays to see which method better detects knee joint damage in adults with hemophilia who have had repeated bleeding in the knee. Researchers will use special scoring systems to measure early and advanced joint changes. The goal is …

This study looks at how other health problems (comorbidities) and certain substances in the blood (biomarkers and microRNAs) affect asthma severity and treatment response in children aged 6 to 12. Researchers will track 82 children for one year to see which kids improve their lun…

This study reviews 300 cases of placenta accreta spectrum (PAS) over 10 years at an Egyptian hospital. PAS is a pregnancy complication where the placenta grows too deeply into the uterine wall, risking severe bleeding. Researchers will compare traditional surgery (removing the ut…

This study will test a non-invasive device called ICON® that measures heart function in COPD patients admitted to the respiratory ICU. Researchers want to see if it is reliable and useful for guiding treatment. The study will enroll 96 adults and track changes in cardiac output d…

This study looks at 88 first-time mothers to see which method—a doctor's exam (Bishop score) or an ultrasound—better predicts if labor induction will lead to a vaginal birth within 24 hours. Participants are full-term pregnant women with a single baby in head-down position. The g…

This study looks at whether a substance in the blood called catestatin is linked to heart and blood vessel problems in people with systemic sclerosis (scleroderma). Researchers will measure catestatin levels in 70 patients and compare them to healthy people. The goal is to see if…

This study will compare two types of thin tubes (catheters) used to give medicine and nutrition to sick newborns in the intensive care unit. Researchers will track 360 babies to see which catheter type causes fewer infections, lasts longer, and leads to fewer complications. The g…

This study uses CT scans to see how a deviated nasal septum (a crooked wall inside the nose) affects the size of the maxillary sinuses and the chance of developing sinusitis. Researchers will compare the deviated side to the normal side in 120 adults. The goal is to better unders…

This study will look at medical and lab factors that influence how children with Guillain-Barré syndrome recover. Researchers will follow 80 children to see which ones fully recover within 3 months. The goal is to create better ways to predict outcomes and guide treatment.

This study will look at 100 adults with myelodysplastic syndromes (MDS) to see if certain blood test results can help predict how the disease will progress. Researchers will check levels of hemoglobin, albumin, lymphocytes, platelets, and other factors. The goal is to better unde…

This study will check for hormone problems in 30 children with Wilson's disease, aged 3 to 18. Researchers will look at how the pituitary, thyroid, adrenal, and sex glands are working. The goal is to find out how common these issues are and what types occur, which could help impr…

This study will check if doctors at Assiut University Heart Hospital follow European guidelines when implanting pacemakers and similar heart devices. Researchers will track 200 adult patients for up to a year to see if following the guidelines leads to fewer complications like in…

This study will use musculoskeletal ultrasound to look for hidden joint, muscle, and tendon inflammation in 81 people with inflammatory bowel disease (IBD) who have no known arthritis. The goal is to see how common these hidden problems are and to develop a standard ultrasound ch…

This study will track 200 children admitted to the pediatric intensive care unit (PICU) to see how imbalances in minerals like sodium, potassium, and calcium affect their outcomes. Researchers aim to find which imbalances are linked to higher death rates and identify factors that…

This study looks at how much parents and caregivers know about diaper rash (napkin dermatosis) in children up to 2 years old. Researchers will survey 240 parents at Assiut University Hospital to understand their knowledge, attitudes, and practices. The goal is to find patterns an…

This observational study will look at 185 children with epilepsy to find out how many also have ADHD symptoms. Researchers will track changes in ADHD symptoms and quality of life over 12 weeks. The goal is to identify risk factors and understand how ADHD affects epilepsy outcomes…

This study looks at whether a score called CALLY, calculated from routine blood tests, can help predict short-term problems like heart failure or death in people having emergency treatment for a heart attack. Researchers will follow 140 patients for 30 days after their procedure.…

This study will review medical records of 25 children with sickle cell disease to see how often they experience painful vaso-occlusive crises and what complications arise. Researchers hope to identify risk factors that could lead to better care. No new treatments are being tested…

This study will follow 300 premature babies (born before 34 weeks and weighing under 1500 grams) to see how often they develop bleeding in the brain, what factors increase the risk, and what short-term health outcomes occur. Researchers will use ultrasound scans in the first week…

This study will observe 125 adults with confirmed stroke to see how factors like symptom awareness, calling emergency services, and transport time affect their recovery. No new treatment is given; instead, researchers will measure stroke knowledge and care pathways to find ways t…

This study looks at body composition—fat, muscle, and bone mass—in children aged 5 to 18 with beta thalassemia major who receive regular blood transfusions. Researchers will use a simple test to measure these body components and see how they relate to transfusion frequency, iron …

This study looks at a little-known bacteria called Providencia that can cause urinary tract infections (UTIs). Researchers will collect samples from 241 patients to identify the germ, test which antibiotics work against it, and look for genes that make it resistant to drugs. The …

This study compares two methods of cutting the uterus during planned C-sections: using scissors versus a scalpel. The goal is to see which tool causes less blood loss. The study will include 140 pregnant women aged 18-40 with a full-term pregnancy (37-42 weeks) who are scheduled …

This study will use a detailed heart ultrasound technique called speckle tracking to look for early signs of heart trouble in 100 adults with inflammatory bowel disease (IBD). Researchers want to see if this method can catch heart changes before they become serious and how those …

This study will check heart disease risk scores in 238 adults with type 2 diabetes who are 40 or older. Researchers want to see if simple, non-invasive measures of belly fat (called LAP and VAI) are linked to higher cardiovascular risk. The goal is to find easier ways to identify…

This study will check how certain leukemia drugs (called tyrosine kinase inhibitors) affect the thyroid gland in people with chronic myeloid leukemia. Researchers will measure thyroid hormone levels in 76 newly diagnosed adults over time. The goal is to learn how often thyroid pr…

This study will track 100 liver transplant patients to see how many develop a new fatty liver condition called MASLD after their transplant. Researchers will also look for risk factors like weight, diabetes, and cholesterol levels. The goal is to better understand this common but…

This study looks at how obesity and gastroesophageal reflux disease (GERD) are connected. Researchers will measure how common obesity is among 200 adults with GERD. The goal is to better understand the link between these two conditions.

This study compares two medications, dexmedetomidine and magnesium sulfate, to see which better controls pressure inside the skull during brain surgery. Sixty adults having elective craniotomy will receive one of the drugs, and their brain pressure will be continuously measured u…

This study will check if a tool called the STARZ score can accurately predict acute kidney injury in newborns admitted to the NICU. Researchers will enroll 140 infants and compare the score's predictions to standard tests. If validated, this simple score could help doctors identi…

This study will check if three heart failure risk models (MAGGIC, GWTG-HF, and SHFM) accurately predict outcomes like death and hospital readmission in 140 Egyptian patients. These models were developed using mostly Western patients, so they may not work well for Egyptians, who t…

This study will examine tissue samples from 50 people with type 1 endometrial cancer to measure levels of a protein called METTL-14. Researchers want to see if higher or lower amounts of this protein are linked to how aggressive the cancer is and how long patients live without th…

This study looks at whether low magnesium levels are linked to sleep problems in people with major depressive disorder. Researchers will measure magnesium in the blood of 90 adults and compare it to their sleep quality. The goal is to better understand this possible connection, n…

This study will examine 138 children with congenital heart disease to find out how many also have chromosomal abnormalities. Researchers will use a standard genetic test called karyotyping to look for missing or extra chromosomes. The goal is to improve diagnosis, treatment plann…

This study looks at whether high uric acid levels can help predict if kidney disease gets worse in people with prediabetes. Researchers will follow 150 adults with prediabetes and early-stage kidney disease to track changes in kidney function over time. The goal is to find a simp…

This study looks at whether the natural drop in blood pressure during sleep (called 'dipping') is linked to changes in the heart's electrical activity in people with high blood pressure. Researchers will monitor 140 adults using a 24-hour blood pressure device and compare those w…

This study looks at whether measuring a type of fat in the blood, called lipoprotein(a), can help predict future heart problems in people who have had a stent placed to open a blocked artery. Researchers will follow 156 adults for one year after their procedure to see if those wi…

This study will follow 50 adults with glioblastoma, an aggressive brain cancer, to see how the amount of tumor removed during surgery affects how long they live. All patients will receive standard radiation and chemotherapy after surgery. The goal is to better understand which su…

This study will survey about 289 medical students and interns at Assiut University to find out how common anxiety and depression are among them. Researchers will use standard questionnaires to measure symptoms and look for links to academic performance and other risk factors. The…

This study looks at whether changes in blood flow can quickly tell doctors if a nerve block has worked for arm surgery. Researchers will measure two blood flow signals in 50 adults before and after the block. If successful, this could help doctors confirm pain relief faster and a…

This study looks at how well ultrasound can find and describe fluid buildup in the belly (ascites) and figure out what's causing it. About 125 people with suspected ascites will get an abdominal ultrasound. The goal is to improve diagnosis, not to test a new treatment.

This study will check if two blood markers (MPV and PDW) can help doctors find deep vein thrombosis early in ICU patients who need a breathing machine. Researchers will follow 100 adults in the ICU and use ultrasound to confirm any clots. The goal is to see if these simple tests …

This study will check 55 adults with gastrointestinal angiodysplasia—abnormal blood vessels in the gut that can cause bleeding—for related blood disorders, especially problems with von Willebrand factor, a protein that helps blood clot. Researchers want to see if low levels of th…

This study will review medical records of 770 women who had C-sections in two hospitals in Assiut, Egypt, during 2026. Researchers will use the WHO's Robson classification system to group women by factors like age and pregnancy history, to see which groups have the most C-section…

This study will follow 100 adults with diabetes and foot ulcers to see how non-vascular factors like nerve damage, infection, and poor blood sugar control affect ulcer severity and healing. Researchers hope to find which risk factors can be changed to prevent ulcers from coming b…

This study looks at people with rectal cancer who have small leftover spots after chemoradiotherapy. One group will have these spots removed with a scope, while the other group will just be watched closely. The goal is to see which approach leads to better cancer control after on…

This study looks at menstrual cycle changes in adolescent girls with diabetes compared to those without. Researchers will track cycle length, frequency, and regularity, and check links to blood sugar control and body weight. The goal is to identify risk factors and improve care f…

This study will follow 645 older adults (65+) who come to the hospital with a heart attack. Researchers want to see if frailty—a state of reduced strength and energy—affects how doctors treat them and whether they have serious problems like death or another heart event within 30 …

This study will survey 340 female students at Assiut University in Egypt to find out how common heavy menstrual bleeding is and how it affects their quality of life and academic performance. Participants will fill out questionnaires and have blood tests to check for anemia and cl…

This study looks at 95 adults with complicated parapneumonic effusion (a lung infection with fluid buildup) to see if doctors can predict which surgical technique is needed: a simpler cleaning (debridement) or a more extensive peel removal (decortication). Researchers will use a …

This study will observe 160 very premature babies (born before 32 weeks and weighing under 1,500 grams) to find out why some fail non-invasive breathing support like CPAP. The goal is to identify risk factors that lead to needing a breathing tube. This is an observational study, …

This study will follow 32 children diagnosed with their first episode of acute disseminated encephalomyelitis (ADEM), a rare brain inflammation that usually follows an infection. Researchers will check if early MRI scans, spinal fluid tests, and symptoms can predict which childre…

This study looks at how sleep disorders and problems with the body's automatic functions (like heart rate control) are linked in elderly people with heart disease. Researchers will study 210 patients aged 65 and older to find out how common sleep issues are and how they affect he…

This study will look at 40 newborns admitted to a neonatal intensive care unit (NICU) to understand why some develop anemia. Researchers will track risk factors from the mother, the birth, and the baby, as well as outcomes like hospital stay length and need for blood transfusions…

This study will analyze bacteria from neck abscesses in 50 patients to understand which germs cause these infections and which antibiotics work best. Researchers will link lab results to patient outcomes like hospital stay length and complications. The goal is to help doctors cho…

This study looks at 70 children aged 1 month to 18 years who have neurological disorders like epilepsy, migraine, or stroke. Researchers will use echocardiograms and ECGs to check for hidden heart problems. The goal is to understand if heart issues are common in these children an…

This study will observe 55 adults with obstructive sleep apnea to see if the severity of their breathing pauses during sleep is linked to higher blood pressure in the lungs. Researchers will use echocardiography to measure lung artery pressure. The goal is to better understand th…

This observational study will check if levels of a fatty substance called lipoprotein(a) in the blood are linked to calcium buildup in heart arteries. About 150 adults at intermediate heart risk will get a CT scan and a blood test. The goal is to see if Lp(a) can help detect earl…

This study will test whether measuring liver tumor volume with CT scans can better assess how well two common treatments—TACE and microwave ablation—are working. Researchers will enroll 66 adults with liver cancer who cannot have surgery. The goal is to improve how doctors track …

This study will look at 100 adults with low platelet counts to see how many have an enlarged spleen and whether that affects their symptoms, complications, or response to treatment. The goal is to better understand the role of the spleen in these blood disorders. No new treatment…

This study will observe 160 infants aged 1 to 12 months who have cow's milk protein allergy and are fed an amino acid-based formula. Researchers will measure weight, length, and head growth over time to see if the formula supports healthy development. The goal is to gather inform…

This study looks at whether a special eye scan (OCT-A) can detect blood vessel changes in the retina of people with multiple sclerosis (MS) and if those changes match up with vision loss. Researchers will scan the eyes of 32 MS patients and test their visual fields. The goal is t…

This study will look at 230 children with Down syndrome and their parents to find out how many have a rare form called translocation Down syndrome. Researchers will use blood tests to check if parents carry a balanced translocation that can be passed down. The goal is to better u…

This study will follow 500 people having a major heart attack (STEMI) to see how the time from symptom onset to balloon treatment affects electrical signals on their ECG and their risk of complications. Researchers will track heart rhythm problems and major events like death or a…

This study will use an overnight sleep test (polysomnography) to measure breathing problems during sleep in 30 adults with systemic sclerosis (scleroderma). The goal is to find out how common sleep-disordered breathing is in this group. No treatment is given—this is purely an obs…

This study looks at hormone changes in 67 children aged 5 to 18 with simple obesity (BMI at or above the 95th percentile). Researchers will measure hormones like insulin, leptin, and cortisol to see how excess weight affects growth and metabolism. The goal is to better understand…

This study will follow 100 children aged 1 to 18 with myocarditis (inflammation of the heart muscle) to see how different types of the disease progress. Researchers will track symptoms, treatments, and outcomes over one year. The goal is to better understand which children recove…

This study looks at whether the bacteria in your gut can affect how your heart heals after a heart attack procedure called PCI. Researchers will measure a substance called TMAO, made by gut bacteria, in 144 patients. The goal is to see if TMAO levels are linked to changes in hear…

This study will track how many children under 18 admitted to Assiut University Children's Hospital have hemolytic uremic syndrome (HUS), a rare condition that damages small blood vessels and can cause kidney failure. Researchers will also describe the patients' age, symptoms, and…

This study will look at 35 children with joint problems that are not caused by inflammation, such as stiffness or deformity. Researchers will use exams, lab tests, and imaging to find the true cause, which could be rare genetic conditions like mucopolysaccharidoses or osteogenesi…

This study will check if certain blood markers—like MCP-1, NLR, and hsCRP—can help detect kidney disease early in people with type 2 diabetes. Researchers will measure these markers in 80 adults and compare them to standard kidney tests. The goal is to find a simpler way to ident…

This study will examine the connection between high uric acid levels (hyperuricemia) and non-alcoholic fatty liver disease (NAFLD) in 111 obese adults. Researchers will use blood tests, ultrasound, and FibroScan to measure uric acid, liver fat, and liver scarring. The goal is to …

This study looks at whether two substances in the blood, called MMP7 and MMP9, can help identify lung disease in people with rheumatoid arthritis. Researchers will compare 81 participants: those with rheumatoid arthritis and lung disease, those with rheumatoid arthritis alone, an…

This study looks at a simple blood test called the triglycerides glucose index in people with type 2 diabetes. Researchers want to see if this index can help predict microvascular complications. The study will follow 200 adults aged 18 to 65.

This observational study will examine the results of genetic testing (karyotyping) in 75 children aged 1 month to 12 years who have both birth defects and developmental delays. Researchers will collect medical histories, perform physical exams, and analyze genetic test results to…

This study looks at whether certain substances in the blood, like surfactant protein-D (SP-D), can help doctors predict how severe a COPD attack will be in hospitalized patients. Researchers will measure these markers in 75 adults admitted for a COPD flare-up and compare them to …

This study will measure vitamin D levels in 84 adults newly diagnosed with immune thrombocytopenia (ITP), a bleeding disorder. Researchers want to see if vitamin D levels are linked to how well patients respond to first-line steroid therapy. The goal is to gather knowledge, not t…

This study will use a thin, flexible camera called an endoscope to look inside the digestive tracts of 50 children aged 6 months to 18 years who are not growing as expected. The goal is to see if this procedure can find hidden gut problems causing their poor growth, and compare t…

This study will follow 45 adults newly diagnosed with chronic lymphocytic leukemia (CLL) for at least one year. Researchers will collect blood samples and genetic information to see how certain markers, like IGHV mutations and chromosome changes, relate to how well patients respo…

This study will enroll 850 adults over 65 who have had a heart attack (acute coronary syndrome). Researchers want to see if adding frailty measurements to standard risk scores improves the prediction of serious bleeding during the hospital stay and up to 6 months later. The goal …

This study will observe 70 adults with rectal bleeding (haematochezia) at Al-Rajhi University Hospital in Egypt. Researchers aim to identify the most common causes and track short-term outcomes. The goal is to improve risk assessment and care for future patients.

This study will enroll 1,000 people with diabetes who are having an emergency procedure to open a blocked artery after a severe heart attack (STEMI). Researchers want to see if certain blood markers of inflammation and clotting can predict complications like heart failure, abnorm…

This observational study will check if having an H. pylori stomach infection is linked to more active lupus in 115 adults. Researchers will use a stool test to detect the bacteria and a standard lupus score to measure disease activity. No treatments are given; the goal is simply …

This study looks at whether argon laser treatment for advanced diabetic eye disease (proliferative diabetic retinopathy) changes the number of cells in the cornea. Researchers will measure corneal cell density before and after laser treatment in 45 patients. The goal is to see if…

This study will check 100 adults on long-term hemodialysis for thyroid problems, abnormal cholesterol, and high uric acid. Researchers want to see how common these issues are and how they relate to each other. The goal is to better understand the health challenges faced by people…

This study will observe 30 people with Behçet's disease at a hospital in Upper Egypt to learn more about their symptoms, lab results, and treatments. Researchers will track how often key signs like mouth ulcers, genital sores, and eye inflammation occur. The goal is to better und…

This study will look at 70 children aged 1 month to 18 years who come to the emergency room with severe breathing problems. Researchers at Assiut University Children Hospital want to find out how common these cases are, what causes them, and which children are most at risk. The g…

This study will measure levels of a protein called IL-33 in the blood of 150 people: lupus patients with kidney inflammation, lupus patients without kidney issues, and healthy volunteers. Researchers want to see if higher IL-33 levels are linked to more severe disease, especially…

This study will look at how well bronchoscopy works to remove objects that children accidentally inhale. About 75 children under 18 with suspected foreign body aspiration will be included. Doctors will use either a rigid or flexible scope to find and remove the object, and then c…

This study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…

This study will measure the width of the medial rectus tendon in 28 people having surgery for crossed eyes (esotropia). The goal is to see if tendon width is linked to how much the eye position changes after surgery. If a link is found, it could help surgeons plan more precise op…

This study will follow 60 children diagnosed with supraventricular tachycardia (SVT) at Assiut University Children Hospital. Researchers aim to see how well current treatments work and how often the condition comes back. The goal is to improve care for children with this fast hea…