Head-to-Head: which new heart valve is best for aortic stenosis?
NCT ID NCT07545369
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial compares two latest-generation heart valves (SAPIEN 3 Ultra Resilia and Evolut FX) in 200 patients with severe aortic stenosis. Participants will be randomly assigned to receive one valve during a standard procedure and followed for one year. The goal is to see which valve works better and has fewer complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SAPIEN 3 Ultra Resilia and Evolut FX transcatheter aortic valves
What this could lead to
If successful, this could show which valve type works better for patients with severe aortic stenosis, helping doctors choose the best option.
What could go wrong
This is a small, early-stage trial with only 200 participants, so results may not apply to all patients. Both valves are already approved, so no major breakthrough is expected.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Assiut University Heart Hospital
Asyut, Assiut Governorate, 71515, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••