Assiut University

This study compares three surgical techniques for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall. The goal is to find which method causes the least blood loss during delivery. The trial will enroll 42 pregnant women with this cond…

This trial tests a new surgical method to treat pelvic organ prolapse in women having a hysterectomy. The surgeon uses special ligaments to support the vaginal vault. Ten women will take part, and the study will measure how much the prolapse improves.

This study tests a new open surgery method called TREPP for fixing inguinal hernias. The goal is to reduce long-term groin pain and hernia recurrence. Researchers will follow 30 adults for up to a year after surgery.

This study tests whether adding the antibiotic azithromycin to standard treatment helps people with idiopathic pulmonary fibrosis (IPF) recover faster from sudden, severe flare-ups. Researchers will compare hospital stay length and other outcomes between those who get azithromyci…

This study tests two breathing support devices—high-velocity nasal cannula (HVNI) and non-invasive ventilation (NIV)—in 80 adults with Guillain-Barré syndrome who have serious breathing trouble. The goal is to see which device helps more patients avoid needing a breathing tube wi…

This study compares two noninvasive breathing devices—BIPAP and a high-velocity nasal cannula—to see which helps patients recover faster from respiratory failure after major surgery. About 180 adults who develop breathing problems within 48 hours after surgery will be randomly as…

This study tests a modified surgical procedure to lower eye pressure in 20 glaucoma patients whose previous combined cataract and glaucoma surgery did not work well. The surgery avoids a certain eye layer to improve success. The main goal is to see if it safely reduces eye pressu…

This study compares two surgical techniques for treating undescended testicles in children. The goal is to see which method—cutting or tying off a blood vessel—better helps the testicle move into the scrotum during a second surgery. About 58 children with undescended testicles wi…

This study tests whether giving tranexamic acid early after a traumatic brain injury can reduce harmful inflammation. Researchers will enroll 60 adults with mild or moderate head injuries. The goal is to see if this drug can help control the body's inflammatory response and impro…

This study tests a surgery called ACL augmentation for people with a partial tear of the anterior cruciate ligament (ACL) in the knee. The goal is to improve knee function and stability. The study will enroll 30 participants aged 15 to 50 who have a partial ACL tear and no other …

This trial tests a surgical procedure that uses a strip of the gluteus maximus (buttock) muscle to create a new sphincter for people with severe bowel incontinence. The surgery is for patients who have not gotten better with standard treatments and have a damaged or missing anal …

This study tests whether giving tranexamic acid (TXA) during hip reconstruction in children reduces blood loss and the need for blood transfusions. About 400 children will be randomly assigned to receive TXA, a nerve block, or standard care. The goal is to make surgery safer and …

This study tests whether a silver liquid (silver diamine fluoride) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3 to 8. Each child will get both treatments on different sides of their mouth. The goal is to see which one works bette…

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases, such as COPD, pneumonia, and pulmonary edema. Researchers will measure LSI in 700 adults with various lung conditions and healt…

This study tests whether a simpler MRI scan (bp-MRI) can accurately diagnose bladder cancer and tell if it has spread into the muscle, without needing a contrast dye injection. Researchers will compare the new method to the standard MRI in 58 adults suspected of having bladder ca…

This study tests whether a special type of MRI (multiparametric MRI) can predict early on if chemotherapy is working for muscle-invasive bladder cancer. 39 participants will get three MRI scans: before chemo, one day after the first dose, and after finishing chemo. The goal is to…

This study compares two ways to help people with bronchiectasis breathe easier during a sudden worsening of their condition. Twenty patients in the ICU will receive either a high flow nasal cannula or non-invasive ventilation. Researchers will measure how long patients stay in th…

This study tests whether a newer breathing machine (HVNI) works better than standard noninvasive ventilation (NIV) for adults with pneumonia who are having trouble breathing. About 100 participants will be randomly assigned to one of the two machines. The main goal is to see whic…

This study tests a behavioral therapy for adults with chronic cough that persists despite standard treatments. Participants must have signs of laryngeal hyperresponsiveness, like coughing when talking or in cold air. The goal is to see if the therapy improves cough-related qualit…

This study compares two types of nerve blocks (pectoral nerve block vs. paravertebral block) given during mastectomy to see which better prevents chronic pain. Ninety women aged 20-65 undergoing mastectomy will be randomly assigned to one of the two blocks. The goal is to reduce …

This study tests two different nerve blocks to see which one better controls pain after open-heart surgery. 90 adults aged 40-60 having coronary bypass will get one of the blocks or a sham procedure. The goal is to reduce pain and the need for extra painkillers, helping patients …

This study tests whether adding blood flow restriction (BFR) training to standard physical therapy helps teenagers with spasmodic flatfoot more than therapy alone. Forty teens under 18 with rigid, painful flatfeet that didn't improve with initial treatment will be randomly assign…

This study compares two drugs, dexmedetomidine and ketamine, to see which one better helps diaphragm function and pain in people with three or more broken ribs who are not having surgery. Sixty adults will receive a low-dose infusion of one drug or a placebo for five days. The go…

This study tests whether giving a numbing medicine (bupivacaine) as a mist before surgery can lower pain and the need for extra painkillers in children aged 1-7 having cleft palate repair. Half the children get the mist, half get a placebo, and neither the doctors nor families kn…

This study looks at whether a specific nerve block (erector spinae plane block) can help control pain after laparoscopic abdominal surgery. About 50 adults undergoing these surgeries will receive the block, and researchers will measure how long it takes before they need extra pai…

This study tests if a nerve block (TAP block) is as good as or better than an epidural for pain after major abdominal cancer surgery. About 50 adults having surgeries like stomach, colon, or liver removal will be randomly assigned to one of the two methods. The goal is to see whi…

This study compares two minimally invasive procedures—semi-rigid and flexible ureteroscopy—for removing upper ureter stones smaller than 2 cm. Researchers will measure which method clears stones more effectively, how long the surgery takes, and overall costs. The trial enrolls 10…

This study compares two ways to sedate children before cleft palate repair: a combination of two drugs (dexmedetomidine and ketamine) given through a nebulizer versus dexmedetomidine alone. The goal is to see which approach works better for calming the child before surgery and pr…

This study tests a new surgical approach for women with a uterine niche (a small pocket in the C-section scar) that causes abnormal bleeding. The procedure combines two steps: first, a hysteroscopy to remove unhealthy tissue, then a laparoscopy to cut out and repair the scar. Res…

This study is testing whether a rectus sheath block, a numbing injection into the abdominal wall, can improve breathing and reduce pain in 60 adults undergoing major upper abdominal surgery. Participants will receive the block and be monitored for diaphragm movement and pain leve…

This study will use 2D and 3D ultrasound to measure vaginal laxity and bladder neck descent in 150 women who have had children. The goal is to better understand pelvic floor changes after vaginal delivery or C-section. Participants will fill out a questionnaire and undergo a non-…

This study looks at basic blood and clotting measures in children with type 1 diabetes compared to healthy children. Researchers want to see if diabetes causes changes in red blood cells or clotting that could lead to complications. The study involves children aged 1 month to 18 …

This study looks at patients who develop pneumonia while in the hospital and later need a breathing tube (mechanical ventilation). Researchers want to learn how common this is and what factors affect recovery. About 151 adults from Assiut University will take part. The goal is to…

This study looks at two surgical methods for early-stage endometrial cancer: laparoscopy (keyhole surgery) and laparotomy (open surgery). It aims to see which one helps patients recover faster, especially in places with limited medical resources. About 48 women will take part, an…

This study follows 30 patients who receive a temporary stoma (ileostomy or colostomy) placed through the midline incision during abdominal surgery. Researchers want to see if this approach lowers the risk of complications like hernias and wound infections compared to traditional …

This observational study is developing a computer model to identify different types of bronchiectasis in adults. Researchers will collect health data from 750 participants over time to see if they can predict disease patterns. No treatments or interventions are given; participant…

This study is creating a new scoring system called BASE to measure how severe bronchiectasis is and predict the chance of a flare-up over the next year. Researchers will follow 750 adults with non-cystic fibrosis bronchiectasis for 12 months, collecting routine medical data. No n…

This study looks at how having heart problems affects the severity of lung flare-ups and quality of life in people with bronchiectasis (a chronic lung condition). Researchers will compare 30 adults with bronchiectasis who also have heart conditions to those without heart issues. …

This study is developing and testing a new tool called the CLEAR model to help doctors predict when people with severe COPD can safely stop using a ventilator or non-invasive breathing support. Researchers will enroll 400 adults in the ICU and track how well the model predicts su…

This study compares two recovery approaches after surgery for pelvic fractures: starting to put weight on the leg immediately versus waiting a while. Researchers will track 50 adults aged 18 to 55 to see which group has better function, less pain, and stronger muscles. The goal i…

This study looks at why some samples from thyroid nodule biopsies are not good enough for diagnosis. About 160 people with thyroid nodules will have their biopsy samples checked right away to see if more samples are needed. The goal is to find factors that lead to poor samples, s…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) earlier than standard tests. Researchers will compare ultrasound images with nerve conduction studies …

This trial is investigating whether chemotherapy given before bladder removal surgery affects how accurate MRI scans are at staging muscle-invasive bladder cancer. Researchers will compare MRI results with actual tumor findings after surgery in 76 participants who either received…