Assiut University

This study tests whether giving children a medicine called tranexamic acid (TXA) during hip surgery can reduce blood loss and the need for blood transfusions. About 400 children having hip reconstruction will be randomly assigned to receive TXA or a placebo. The goal is to see if…

This study tests whether adding the antibiotic azithromycin to usual care can help people hospitalized with a sudden worsening of idiopathic pulmonary fibrosis (IPF). About 30 adults with mild to moderate IPF will be randomly assigned to receive either azithromycin plus standard …

This study tests whether a silver liquid (SDF) or a standard fluoride varnish is better at reducing cavity-causing bacteria in children aged 3-8 with cavities on both sides of the mouth. Each child gets both treatments, one on each side, and bacteria levels are checked over 3 mon…

This study tests a surgery that uses a muscle from the buttock to help people with severe bowel incontinence who haven't gotten better with other treatments. The surgery aims to improve bowel control and quality of life. The study will include 10 adults who have a damaged anal sp…

This study compares two surgical techniques for treating undescended testicles in boys. The goal is to see which method better helps the testicle move into the scrotum. About 58 boys with undescended testicles will take part. The study measures how far the testicle moves and its …

This study tests whether giving tranexamic acid early after a traumatic brain injury can lower harmful inflammation. Researchers will measure inflammation using a blood test called NLR. The trial enrolls 60 adults with mild to moderate head injuries, treated within 8 hours.

This study is testing a modified type of glaucoma surgery (trabeculectomy) to help control eye pressure in patients whose earlier combined cataract and glaucoma surgeries did not work well. The study will include 20 adults who have already had cataract surgery combined with eithe…

This study is testing a surgical technique to repair partially torn anterior cruciate ligaments (ACL) in the knee, rather than replacing the whole ligament. Researchers will enroll 30 people aged 15 to 50 who have a partial ACL tear. The goal is to see if this less invasive appro…

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases like COPD, pneumonia, and fluid in the lungs. About 700 adults with various lung conditions and healthy volunteers will get a lu…

This study tests whether a simpler, non-contrast MRI (called biparametric MRI) can accurately diagnose bladder cancer and determine if it has invaded the muscle. Researchers will compare this method to the standard contrast-enhanced MRI in 58 participants suspected of having blad…

This study looks at whether a rectus sheath block—a type of nerve block—can improve breathing and reduce pain after major upper abdominal surgery. Researchers will measure diaphragm movement and pain levels in 60 adults. The goal is to find a better way to manage recovery after s…

This study tests whether adding blood flow restriction (BFR) training to standard physical therapy can improve pain, movement, and function in adolescents with spasmodic flatfoot. Forty teens who haven't improved with initial treatment will be randomly assigned to receive either …

This study compares two ways to sedate children before cleft palate repair surgery and prevent confusion or agitation after waking up. Sixty children will receive either a combination of two drugs (dexmedetomidine and ketamine) or dexmedetomidine alone through a nebulizer (a mach…

This study looks at whether a specific nerve block, called the erector spinae plane block, can help control pain after laparoscopic abdominal surgery. Researchers will measure how long it takes for patients to need extra pain medicine and how much morphine they use. The study inv…

This study looks at two types of nerve blocks (pectoral nerve block and paravertebral block) given during mastectomy to see which one better prevents chronic pain. About 90 women having mastectomy will be randomly assigned to one of the blocks. The goal is to reduce long-term pai…

This study compares two types of breathing support—noninvasive ventilation (NIV) and high-velocity nasal cannula (HVNC)—for adults who develop respiratory failure within 48 hours after major surgery. The goal is to see which method helps patients wean off breathing support faster…

This study tests whether using throat packs soaked in a steroid medicine (dexamethasone) can lower the chance of a sore throat after septoplasty (nose surgery). About 90 adults having planned septoplasty will take part. The main goal is to see how many people have a sore throat i…

This study tests two types of breathing support for 70 adults with Guillain-Barré syndrome who have serious breathing trouble. One method uses a high-flow nasal cannula, and the other uses a mask that helps with both inhaling and exhaling. The main goal is to see which method hel…

This study tests whether behavioral therapy can ease chronic cough in adults whose cough persists despite standard treatments. Participants must have signs of laryngeal hyperresponsiveness, like coughing when talking or in cold air. The study will measure changes in cough severit…

This study tests a combined hysteroscopic and laparoscopic surgery to repair a uterine niche (a pocket in the scar from a C-section) that causes abnormal bleeding. About 30 women with postmenstrual spotting will receive the procedure. The goal is to see if the surgery can stop th…

This study looks at whether starting to walk right after pelvic fracture surgery is better than waiting. About 50 adults aged 18 to 55 who had pelvic fixation will be randomly assigned to either immediate or delayed weight bearing. The goal is to see which approach improves funct…

This study tests two low-dose medicines (dexmedetomidine and ketamine) to see which one better helps pain, diaphragm function, and inflammation in adults with three or more broken ribs who are treated without surgery. About 60 participants will receive one of the drugs for five d…

This study compares two types of nerve blocks (TTPB and PIFB) to see which provides better pain relief after open heart surgery. About 90 adults aged 40-60 having coronary artery bypass will receive one of the blocks. The goal is to reduce pain scores and the need for extra pain …

This study tests whether a nebulized (mist) form of tranexamic acid, a drug that helps blood clot, can reduce bleeding during sinus surgery. About 90 adults having sinus surgery will receive either the drug or a placebo. The goal is to see if it makes surgery easier for the surge…

This study tests if a nerve block (TAP block) is as safe and effective as an epidural for pain relief after major abdominal cancer surgery. About 50 adults having surgeries like stomach or colon removal will be enrolled. The goal is to see which method reduces the need for extra …

This study compares two breathing treatments for people with bronchiectasis who are in the hospital with a sudden worsening of symptoms. It looks at whether a high flow nasal cannula works as well as non-invasive ventilation (a mask that helps breathing). The goal is to see which…

This study looks at whether giving children a single dose of dexmedetomidine during cleft palate repair can prevent agitation right after surgery. About 60 children aged 1-7 will be randomly assigned to receive either the drug or a placebo (saline). The main goal is to see if the…

This study compares two minimally invasive procedures—semi-rigid and flexible ureteroscopy—to treat upper ureter stones smaller than 2 cm. About 100 adults with such stones will be randomly assigned to one of the two methods. The goal is to see which approach clears stones more e…

This study is testing whether a pain medication (bupivacaine), given as a mist to breathe in before surgery, can better control pain in children after cleft palate repair. It will compare the mist to a placebo (saltwater) in 60 children aged 1-7 years. The main goal is to see if …

This study looks at whether chemotherapy given before bladder cancer surgery makes MRI scans less accurate at showing the tumor stage. About 76 people with muscle-invasive bladder cancer will take part. Half will get chemotherapy before surgery, and half will go straight to surge…

This study looks at what makes some thyroid nodule biopsy samples unusable for diagnosis. Researchers will collect samples from 160 people and check them right away to see if they are good enough. The goal is to find ways to get better samples the first time, so fewer people need…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Researchers will compare ultrasound images with standard nerve tests to see if ultrasound can help di…

This study aims to see if special MRI scans taken early during chemotherapy can predict whether the treatment is working for people with muscle-invasive bladder cancer. About 39 participants will get three MRI scans before, during, and after chemo. If successful, this approach co…