Assiut University

This study tests whether a silver liquid (silver diamine fluoride) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3 to 8 with tooth decay. Each child will receive both treatments on different sides of their mouth. The researchers wil…

This study tests a surgery that uses a muscle from the buttock to help people with severe bowel leakage that hasn't improved with other treatments. The surgery aims to create a new sphincter to improve control. The study will include 10 adults who have a damaged anal sphincter an…

This study tests a modified version of trabeculectomy, a surgery to lower eye pressure, in 20 people whose prior combined cataract and glaucoma surgery started to fail early. The goal is to see if this modified approach can better control intraocular pressure. Participants must h…

This study tests whether adding the antibiotic azithromycin to usual care can help people hospitalized with a sudden worsening of idiopathic pulmonary fibrosis (IPF). About 30 adults with mild to moderate IPF will be randomly assigned to receive either azithromycin plus standard …

This study tests a surgical technique to repair partially torn anterior cruciate ligaments (ACL) in the knee. It will include 30 people aged 15 to 50 with a partial ACL tear and no other ligament damage. The goal is to see if the surgery improves knee function and stability, meas…

This study tests whether giving tranexamic acid early after a traumatic brain injury can lower harmful inflammation. Researchers will measure inflammation using a blood test called NLR. The trial enrolls 60 adults with mild to moderate head injuries, treated within 8 hours.

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases like COPD, pneumonia, and pneumothorax. Researchers will enroll 700 adults with various lung conditions and healthy volunteers t…

This study tests whether a shorter, dye-free MRI scan (called bp-MRI) can accurately diagnose bladder cancer and tell if it has spread into the muscle. Researchers will compare this simpler scan to the standard contrast MRI in 58 adults suspected of having bladder cancer. If succ…

This study tests two low-dose medicines (dexmedetomidine and ketamine) to see which one better helps pain and diaphragm function in people with multiple broken ribs who are treated without surgery. About 60 adults aged 18-65 with at least three broken ribs and severe pain will ta…

This study tests a new surgical technique that uses two types of scopes (hysteroscope and laparoscope) to repair a scar defect in the uterus caused by a previous C-section. The goal is to reduce abnormal bleeding and increase the thickness of the remaining uterine muscle. About 3…

This study tests whether giving children a medicine called tranexamic acid (TXA) during hip reconstruction surgery can reduce blood loss and the need for blood transfusions. About 400 children scheduled for hip surgery will be randomly assigned to receive TXA or a placebo. The go…

This study looks at whether starting to walk right after pelvic fracture surgery helps people recover better than waiting. Researchers will measure pain, walking ability, and quality of life in 50 adults aged 18 to 55. The goal is to find the best way to help patients get back on…

This study compares two ways to cut or tie off blood vessels during the first stage of a two-part surgery for undescended testicles in children. The goal is to see which method helps the testicle move into the right position better. About 58 children with undescended testicles wi…

This study compares two common procedures—semi-rigid and flexible ureteroscopy—for removing upper ureter stones smaller than 2 cm. Researchers will measure how well each method clears stones, how long the surgery takes, and the costs involved. 100 adults with upper ureter stones …

This study tests if a nebulized (mist) form of tranexamic acid, a drug that helps blood clot, can reduce bleeding during sinus surgery. About 90 adults having sinus surgery will receive either the drug or a placebo. The goal is to see if the drug makes surgery easier for the surg…

This study tests two types of nerve blocks (TTPB and PIFB) to see which one provides better pain relief after open heart surgery. About 90 adults aged 40 to 60 will receive one of the blocks, and researchers will measure how much extra pain medicine they need and their pain level…

This study looks at whether a rectus sheath block, a type of nerve block, can improve breathing and reduce pain after major upper abdominal surgery. About 60 adults having planned surgery with a midline cut will be included. Researchers will measure diaphragm movement and pain sc…

This study looks at two types of nerve blocks (pectoral nerve block and paravertebral block) to see which one better prevents long-term pain after mastectomy. About 90 women having mastectomy will be randomly assigned to one of the two blocks. The goal is to reduce the chance of …

This study tests whether adding blood flow restriction (BFR) training to standard physical therapy can improve pain, movement, and function in adolescents with spasmodic flatfoot. Forty teens who haven't improved with initial treatment will be randomly assigned to receive either …

This study compares two breathing support methods for people with bronchiectasis who are having a sudden worsening of symptoms. It will test if a high flow nasal cannula works as well as non-invasive ventilation and is easier for patients to tolerate. The study involves 20 adults…

This study compares two ways to sedate children before cleft palate repair surgery and prevent confusion or agitation after waking up. Sixty children will receive either a combination of two drugs (dexmedetomidine and ketamine) or dexmedetomidine alone through a nebulizer (a mach…

This study looks at whether a specific nerve block, called the erector spinae plane block, can help control pain after laparoscopic abdominal surgery. Researchers will measure how long it takes for patients to need extra pain medicine and how much morphine they use. The study inv…

This study compares two types of breathing support—noninvasive ventilation (NIV) and high-velocity nasal cannula (HVNC)—for adults who develop respiratory failure within 48 hours after major surgery. The goal is to see which method helps patients wean off breathing support faster…

This study tests two types of breathing support for 70 adults with Guillain-Barré syndrome who have serious breathing trouble. One method uses a high-flow nasal cannula, and the other uses a mask that helps with both inhaling and exhaling. The main goal is to see which method hel…

This study tests whether behavioral therapy can ease chronic cough in adults whose cough persists despite standard treatments. Participants must have signs of laryngeal hyperresponsiveness, like coughing when talking or in cold air. The study will measure changes in cough severit…

This study tests if a nerve block (TAP block) is as safe and effective as an epidural for pain relief after major abdominal cancer surgery. About 50 adults having surgeries like stomach or colon removal will be enrolled. The goal is to see which method reduces the need for extra …

This study is testing whether a pain medication (bupivacaine), given as a mist to breathe in before surgery, can better control pain in children after cleft palate repair. It will compare the mist to a placebo (saltwater) in 60 children aged 1-7 years. The main goal is to see if …

This study looks at how having heart problems affects the severity of sudden worsening of symptoms (flare-ups) in people with bronchiectasis, a chronic lung condition. Researchers will measure a heart-related protein (BNP) and quality of life in 30 participants with both conditio…

This study looks at factors that can make thyroid nodule biopsy samples unusable, so doctors can get a clear diagnosis the first time. Researchers will collect samples from 160 people with thyroid nodules and check them right away for quality. The goal is to find ways to reduce r…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Researchers will compare ultrasound images with standard nerve tests to see if ultrasound helps diagn…

This study explores whether special MRI scans taken early during chemotherapy can predict if the treatment is working for muscle-invasive bladder cancer. Researchers will scan 39 patients before, during, and after chemotherapy to see if changes in tumor blood flow and cell densit…

This study looks at whether chemotherapy given before bladder cancer surgery changes how well an MRI can see the tumor. Researchers will compare MRI results from patients who had chemo first to those who went straight to surgery. The goal is to see if chemo-related tissue changes…

This study is testing a new tool called CLEAR to help doctors predict when people with severe COPD can safely stop using breathing machines. Researchers will watch 400 adults in the ICU who are ready to try breathing on their own. The goal is to see if the CLEAR tool works better…