Which breathing aid works best for Guillain-Barré? new trial aims to find out

NCT ID NCT06996509

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two breathing support devices—high-velocity nasal cannula (HVNI) and non-invasive ventilation (NIV)—in 80 adults with Guillain-Barré syndrome who have serious breathing trouble. The goal is to see which device helps more patients avoid needing a breathing tube within 30 days. Researchers will also measure comfort, ICU and hospital stays, and survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
High-Velocity Nasal Insufflation (HVNI) device and Non-Invasive Ventilation (NIV) device
What this could lead to
If one device works better, it could help more Guillain-Barré patients breathe without needing a breathing tube, reducing complications and hospital stays.
What could go wrong
This is a small, early-stage trial (80 patients) at one hospital, so results may not apply to everyone. Both devices are already used, so no major new risks, but individual responses vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Assuit Univeristy

    RECRUITING

    Asyut, Assuit, 71515, Egypt

  • Faculty of Medicine - Assiut University Hospitals - Assiut University - Egypt

    RECRUITING

    Asyut, 71515, Egypt

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