Can a simple blood test unlock the secrets of brain autoimmune diseases?

NCT ID NCT06502015

Recruiting now Knowledge-focused Sponsor: Tongji Hospital Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study aims to discover biological markers (biomarkers) that could help doctors diagnose and track neurological autoimmune diseases such as multiple sclerosis, myasthenia gravis, and Guillain-Barre syndrome. Researchers will analyze samples from 50,000 people, including patients with these conditions and healthy volunteers. The goal is to find stable, reliable indicators that enable earlier diagnosis and personalized treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to earlier diagnosis and better monitoring of neurological autoimmune diseases, potentially improving treatment and quality of life.
What could go wrong: This is an observational study, so it will not test a treatment. Finding reliable biomarkers is challenging, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy acute disseminated encephalomyelitis autoimmune disease autoimmune disorder of the nervous system autoimmune encephalitis chronic inflammatory demyelinating polyradiculoneuropathy Guillain-Barre syndrome idiopathic inflammatory myopathy multiple sclerosis myasthenia gravis myelin oligodendrocyte glycoprotein antibody-associated disease myositis disease neuromyelitis optica stiff-person syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DISSEMINATED ENCEPHALOMYELITIS AUTOIMMUNE DISEASES AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM AUTOIMMUNE ENCEPHALITIS CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY GUILLAIN-BARRE SYNDROME IDIOPATHIC INFLAMMATORY MYOPATHIES MULTIPLE SCLEROSIS MYASTHENIA GRAVIS NEUROMYELITIS OPTICA SPECTRUM DISORDER STIFF PERSON SYNDROME

Contacts and locations

Locations

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, 430030, China

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