NEUROMYELITIS OPTICA SPECTRUM DISORDER

This study is testing a medication called ravulizumab to see if it can safely prevent relapses in children and adolescents with a rare autoimmune disease called NMOSD. The disease attacks the nerves in the eyes and spinal cord. Researchers will compare the relapse rate in partici…

This early-stage study is testing if a drug called ofatumumab can safely reduce relapses and slow disability in adults with a rare and severe autoimmune nerve disorder called NMOSD. The drug works by targeting and depleting specific immune cells (B cells) thought to drive the dis…

This study is testing a medication called inebilizumab in children aged 2 to 18 who have a rare autoimmune disease that attacks the nerves in the eyes and spinal cord. Researchers want to understand how the drug behaves in children's bodies, how safe it is, and if it helps contro…

This study aims to collect long-term, real-world data on how well specific C5 inhibitor medications control relapses and affect quality of life for adults with AQP4+ NMOSD, a rare autoimmune disorder that attacks the nerves in the eyes and spinal cord. It will follow 122 particip…

This study is testing a drug called satralizumab in children aged 2 to 11 who have a rare autoimmune disease called NMOSD, which attacks the nerves in the eyes and spinal cord. The main goal is to see how the drug behaves in children's bodies and to check if it helps prevent dise…

This study aims to gather information about how pregnancy affects women with multiple sclerosis (MS) and related conditions. Researchers will follow 1,500 pregnant women and their children for up to six years to understand the safety of medications, the impact on disease progress…

This study aims to understand the safety of the NMOSD medication UPLIZNA during pregnancy. It will follow about 60 women who received the drug while pregnant or just before conception. Researchers will collect information over 10 years to monitor birth outcomes and infant health,…