New hope for kids with rare nerve disease: satralizumab trial begins

NCT ID NCT05199688

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 4 times

Summary

This study tests a drug called satralizumab in children aged 2 to 11 who have a rare autoimmune disease called NMOSD. The main goal is to see how the drug moves through the body and if it can safely reduce relapses. Only 8 children will take part, and the results will help doctors understand if this treatment works for younger patients.

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Conditions

The condition(s) this trial relates to.

neuromyelitis optica neuromyelitis optica spectrum disorder with anti-AQP4 antibodies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROMYELITIS OPTICA SPECTRUM DISORDER NMOSD

Contacts and locations

Locations

Centre Hospitalier Universitaire de Bicêtre
RECRUITING

Le Kremlin-Bicêtre, Val-de-Marne, 94275, France
Children's Hospital Colorado.
RECRUITING

Denver, Colorado, 80218-1007, United States
Children's Hospital of Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 201102, China
Clinica Universitaria Reina Fabiola
RECRUITING

Córdoba, X5004FHP, Argentina
Fondazione Istituto Neurologico Mondino IRCCS
RECRUITING

Pavia, Lombardy, 27100, Italy
Great Ormond Street Hospital for Children
RECRUITING

London, WC1N 3JH, United Kingdom
Grupo Medico Camino
RECRUITING

DF, Mexico CITY (federal District), DUMMY_VALUE, Mexico
Guangzhou Women and Children's Medical Center
RECRUITING

Guangzhou, Guangdong, 510120, China
Hospital de Pediatría S.A.M.I.C.- Prof. Dr. Juan P. Garrahan
RECRUITING

Ciudad Autonoma Buenos Aires, C1249ABN, Argentina
IRCCS Ospedale Pediatrico Bambino Gesù - INCIPIT - PIN
RECRUITING

Rome, Lazio, 00165, Italy
Instytut "Pomnik - Centrum Zdrowia Dziecka"
RECRUITING

Warsaw, 04-730, Poland
Kocaeli University Research and Application Hospit
RECRUITING

Kocaeli, 6810, Turkey (Türkiye)
Uniwersyteckie Centrum Kliniczne
ACTIVE_NOT_RECRUITING

Gda?sk, 80-214, Poland

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