Genetic clues may forecast multiple sclerosis after vision loss
NCT ID NCT07704294
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This observational study looks at whether combining genetic information with standard clinical data can better predict who will develop multiple sclerosis after a first episode of optic neuritis (inflammation of the optic nerve). Researchers will follow 180 people aged 16 and older who have had optic neuritis, collecting saliva for genetic analysis and reviewing medical records. The goal is to develop a prognostic tool that could help guide care and improve understanding of future health risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a tool that helps doctors predict who will develop multiple sclerosis after optic neuritis, enabling earlier monitoring and care.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find a strong enough link between genetics and MS risk to create a useful prediction tool.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Guy's and St Thomas' NHS Foundation Trust
London, SE1 7EH, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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King's College Hospital NHS Foundation Trust
London, SE5 9RS, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Moorfields Eye Hospital NHS Foundation Trust
London, EC1V 2PD, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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