Can a blood pressure pill slow MS disability?

NCT ID NCT07765212

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This phase 2 trial tests whether indapamide, a common diuretic, can slow the worsening of walking ability in people with progressive multiple sclerosis (MS). Participants take one tablet daily for 12 months, with walking speed measured regularly. The study aims to see if the drug reduces the rate of disability progression in this hard-to-treat form of MS.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
indapamide, a diuretic medication taken as a daily tablet
What this could lead to
If successful, this could point toward a new treatment to slow disability progression in people with progressive forms of multiple sclerosis.
What could go wrong
This is an early-stage, open-label trial with no placebo group, so results may be inconclusive or not generalizable. Indapamide's safety and effectiveness for MS are unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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