New hope for GBS: Single-Dose drug enters final testing

NCT ID NCT07020819

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single dose of tanruprubart (ANX005) in 30 adults and children with Guillain-Barré syndrome (GBS), a rare nerve disorder that causes weakness. The goal is to see how the drug works in the body, its early effects, and its safety. Participants must have GBS symptoms for 10 days or less and have not received standard treatments like plasma exchange or IV immunoglobulin.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Aarhus N, 8200, Denmark

  • Children's Hospital of Orange County

    RECRUITING

    Orange, California, 92868, United States

  • Henry Ford Health

    RECRUITING

    Detroit, Michigan, 48202, United States

  • HonorHealth Bob Bové Neuroscience Institute

    RECRUITING

    Scottsdale, Arizona, 85251, United States

  • Mayo Clinic Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

  • Mayo Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Ochsner LSU Health

    RECRUITING

    Shreveport, Louisiana, 71101, United States

  • Profound Research LLC

    RECRUITING

    Carlsbad, California, 92011, United States

  • St. Joseph's Hospital & Medical Center - Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • University Massachusetts Chan Medical School

    RECRUITING

    Worcester, Massachusetts, 01655, United States

  • University of California Irvine

    RECRUITING

    Orange, California, 92868, United States

  • University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

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Other studies related to the condition(s) this trial covers.