Can a sedative help heal broken ribs? new trial aims to find out

NCT ID NCT04928300

Recruiting now Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two drugs, dexmedetomidine and ketamine, to see which one better helps diaphragm function and pain in people with three or more broken ribs who are not having surgery. Sixty adults will receive a low-dose infusion of one drug or a placebo for five days. The goal is to improve breathing and reduce pain, which could speed recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine (a sedative) and ketamine (an anesthetic)
What this could lead to: If it works, this could point toward a better way to manage pain and improve breathing in people with multiple broken ribs, reducing complications.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Both drugs have side effects like sedation or confusion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone fracture Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RIB FRACTURES

Contacts and locations

Locations

Assiut university hospital
RECRUITING

Asyut, Assuit, Assuit universi, Egypt

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