Assiut University
Clinical trials sponsored by Assiut University, explained in plain language.
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Battle of the scopes: which kidney stone surgery wins?
Disease control CompletedThis study compared two minimally invasive surgeries for removing kidney stones up to 2 cm in size: flexible ureteroscopy (a scope through the urinary tract) and mini-PCNL (a tiny incision in the back). 118 adults took part. The main goal was to see which method cleared more ston…
Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 09:22 UTC
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Which drug saves kidneys in pre-eclampsia? new study pits phentolamine against GTN
Disease control CompletedThis study looked at 170 women with severe pre-eclampsia in the ICU. It compared two blood pressure medicines, phentolamine and glyceryl trinitrate (GTN), to see which one better protects kidney function. The goal was to find a safer way to control blood pressure and reduce the r…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 09:18 UTC
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Heart surgery fluid showdown: which protects better?
Disease control CompletedThis study tested two different fluids used to protect the heart during bypass surgery. 124 adults having coronary artery bypass surgery received either a modified Ringer's acetate solution or a histidine-tryptophan-ketoglutarate solution. The main goal was to see which fluid hel…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 09:18 UTC
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Muscle relaxants vs. sedation: which helps severe COVID-19 lung failure?
Disease control CompletedThis study looked at 40 patients with severe COVID-19 lung failure who needed a breathing machine. Researchers compared giving muscle relaxants plus sedation versus sedation alone to see which better improved oxygen levels and lung function. The goal was to find better ways to ma…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 09:17 UTC
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Heart drug showdown: which works better during bypass surgery?
Disease control CompletedThis study compared two drugs, levosimendan and adrenaline, given during heart bypass surgery to 60 patients with weak hearts (ejection fraction 30-40%). The goal was to see which drug better supports heart function during and right after surgery. Researchers measured heart pumpi…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 09:09 UTC
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Titanium mesh vs. bone graft: which fixes eye socket fractures better?
Disease control CompletedThis study looked at 80 people who had a broken eye socket bone (orbital floor) after an injury like a car accident or sports impact. Doctors compared two surgical repair methods: using a titanium mesh or a piece of the patient's own hip bone. The goal was to see which method bet…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Mesh may cut hernias after stoma reversal, new study finds
Disease control CompletedThis study tested whether adding a mesh patch during stoma reversal surgery reduces the chance of developing a hernia at the surgical site. Sixty-two patients with temporary stomas were randomly assigned to receive either mesh reinforcement or standard closure. The researchers tr…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Nerve block breakthrough could prevent brain damage after trauma
Disease control CompletedThis study tested two types of nerve blocks (superior cervical sympathetic block and stellate ganglion block) to treat dangerous artery spasms in the brain after a traumatic head bleed. 60 adults aged 18-65 with refractory post-traumatic subarachnoid hemorrhage were enrolled. The…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Simple blood test could spot IBD earlier
Diagnosis CompletedThis study looked at whether certain proteins in the blood can help diagnose inflammatory bowel disease (IBD) more accurately without needing invasive procedures. Researchers measured levels of four markers in 70 newly diagnosed patients before and after treatment. The goal is to…
Sponsor: Assiut University • Aim: Diagnosis
Last updated May 12, 2026 13:43 UTC
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Nerve block may stop shingles pain from becoming chronic
Prevention CompletedThis study tested whether a targeted nerve block, using a numbing medicine and a steroid, could prevent the long-term nerve pain that sometimes follows a shingles outbreak. One hundred adults with shingles on their chest or back received either standard care or standard care plus…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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Nerve block battle: which shot stops hernia pain best?
Symptom relief CompletedThis study tested two different ultrasound-guided nerve blocks to see which one provides better pain relief after inguinal hernia repair. 43 men undergoing hernia surgery received one of the two blocks. The goal was to find the most effective way to reduce post-operative pain.
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:24 UTC
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New pain-block combo may improve recovery after cancer surgery
Symptom relief CompletedThis study tested whether adding dexmedetomidine to a standard numbing medicine (bupivacaine) improves pain relief after major lower abdominal cancer surgery. 54 adults received either a quadratus lumborum block or an epidural block. The main goal was to see how long pain relief …
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:24 UTC
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C-Section pain study: which drug works longer?
Symptom relief CompletedThis study tested two drugs, magnesium sulfate and neostigmine, added to a standard numbing medicine for a belly nerve block after C-section. 68 women received one of the two combinations. Researchers measured how long pain relief lasted and how much extra pain medicine was neede…
Phase: PHASE2, PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:22 UTC
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Which drug stops Post-C-Section shivers best? study reveals answer
Symptom relief CompletedThis study tested two medicines, dexamethasone and dexmedetomidine, to see which one better prevents shivering after a C-section done with spinal anesthesia. A total of 382 women took part. The goal was to find a safer, more effective way to keep new mothers comfortable after sur…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:19 UTC
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Needle vs. voice: which works better for sore throat nodules?
Symptom relief CompletedThis study tested two treatments for vocal nodules (small growths on the vocal cords that cause hoarseness) in 50 adult women. One group received a steroid injection directly into the nodule, while the other group underwent a special voice therapy called the Accent method. The go…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:10 UTC
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Which pain block lasts longest after keyhole lung surgery?
Symptom relief CompletedThis study tested three different pain-relief methods in 102 adults having lung surgery through a single small cut. The goal was to see which method keeps patients comfortable the longest after surgery. Researchers measured how soon patients needed extra pain medicine and how str…
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 17, 2026 09:09 UTC
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New pain-blocking shot could help kids recover from hip surgery with less discomfort
Symptom relief CompletedThis study tested whether an ultrasound-guided nerve block (erector spinae muscle block) can reduce pain after hip reconstruction in 70 children aged 2-7. The goal was to see if it provides better pain relief than standard care and lowers the need for strong pain medicines. Resul…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Soaked packs promise throat relief after nose surgery
Symptom relief CompletedThis study tested whether using throat packs soaked in a steroid medicine (dexamethasone) could reduce sore throat after septoplasty (nose surgery). 65 adults took part. The goal was to see if this simple change could make recovery more comfortable.
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Magnesium may boost pain relief after mastectomy
Symptom relief CompletedThis study tested whether adding magnesium sulfate to a standard nerve block (erector spinae plane block) could improve pain control after breast cancer surgery. Sixty women scheduled for a modified radical mastectomy received the nerve block with or without magnesium. The main g…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Magnesium mist may soothe sore throats after surgery
Symptom relief CompletedThis study tested whether inhaling a magnesium sulfate mist before a breathing tube is placed can reduce sore throat and stress after surgery. 100 adults having gallbladder surgery took part. The goal was to see if this simple treatment could make recovery more comfortable.
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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New study tests safer pain relief for gallbladder surgery
Symptom relief CompletedThis study tested two non-opioid drugs, dexmedetomidine and lidocaine, given continuously during gallbladder surgery to control pain and reduce the need for stronger opioids. 64 adults having laparoscopic cholecystectomy took part. The goal was to see which drug provides better p…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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New recovery plan cuts hospital time for thyroid surgery patients
Symptom relief CompletedThis study tested a special care program called ERAS for people having thyroid surgery. The goal was to see if it could reduce pain, nausea, and time spent in the hospital compared to usual care. 143 adults took part, and the program focused on improving recovery after surgery.
Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New surgical trick cuts ultrasound time for brown cataracts
Symptom relief CompletedThis study tested a small change in cataract surgery for people with brown cataracts. Instead of the usual method, surgeons first rinsed the lens with saline for 30 seconds after making a groove. The goal was to see if this could reduce the time needed for ultrasound power during…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Which drug works better to stop early labor? new study compares nifedipine and magnesium sulfate
Symptom relief CompletedThis study tested two medicines, nifedipine and magnesium sulfate, to see which is better at delaying preterm labor in pregnant women between 32 and 36 weeks. The goal was to postpone delivery for at least 48 hours to allow steroids to help the baby's lungs mature. The trial invo…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Laser showdown: which eye surgery fixes mixed astigmatism best?
Symptom relief CompletedThis study compared two types of laser eye surgery for people with mixed astigmatism, a condition where the eye focuses light unevenly. 39 adults received either femtosecond laser-assisted LASIK or single-step transepithelial photorefractive keratectomy. The goal was to see which…
Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New study tests drug to calm kids after cleft palate surgery
Symptom relief CompletedThis study tested whether a single dose of dexmedetomidine, given during surgery, can prevent agitation in children aged 1-7 years after cleft palate repair. Sixty children were randomly assigned to receive either the drug or a placebo (saline). The main goal was to measure emerg…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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Virtual reality goggles ease Kids' dental dread in new study
Symptom relief CompletedThis study tested whether wearing augmented reality goggles during a tooth extraction could help children aged 6 to 10 feel less pain and anxiety. Sixty kids were split into two groups: one used the goggles as a distraction, while the other received standard care. Researchers mea…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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New combo may cut opioid use for cancer pain
Symptom relief CompletedThis study looked at whether adding duloxetine (a nerve pain drug) to tramadol (a painkiller) can better control chronic cancer pain and reduce the amount of tramadol needed. 400 adults with cancer pain who had not taken painkillers before took part. Half received duloxetine plus…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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New pain block may help hip surgery patients move sooner
Symptom relief CompletedThis study tested two different nerve block techniques to control pain after hip fracture surgery. 96 adults with hip fractures received either a PENG block plus a lateral femoral cutaneous nerve block, or a supra-inguinal fascia iliaca compartment block. The goal was to see whic…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Gentler C-Section method may reduce injury in repeat surgeries
Symptom relief CompletedThis study tested a new way to deliver the baby's head during repeat C-sections, called the external pop out technique. It involved 600 women having an elective repeat C-section. The goal was to see if this method causes less damage to the uterus, reduces blood loss, and shortens…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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New pain cocktail may ease recovery after gallbladder removal
Symptom relief CompletedThis study tested if adding magnesium sulfate or dexmedetomidine to a standard numbing drug (bupivacaine) improves pain control after laparoscopic gallbladder removal. 63 adults undergoing elective surgery received one of three combinations via a nerve block. The goal was to find…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Nutritional support may ease mouth sores in head and neck cancer radiation
Symptom relief CompletedThis study looked at whether active nutritional support can lower the chance of painful mouth sores (mucositis) and improve quality of life in adults with head and neck cancer who are getting radiation therapy. 47 newly diagnosed patients were followed to track their weight and b…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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New combo may stop nausea after C-Section pain relief
Symptom relief CompletedThis study tested whether adding two common drugs (dexamethasone and atropine) to spinal anesthesia could prevent nausea and vomiting caused by morphine in women having planned C-sections. 150 women received either one or both drugs, or a placebo, alongside their spinal anesthesi…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 12, 2026 13:41 UTC
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Newer nerve block may ease broken rib pain with fewer risks
Symptom relief CompletedThis study compared two types of nerve blocks for pain relief in 60 adults with multiple broken ribs. One is a newer, easier technique called retrolaminar block (RLB), and the other is the standard paravertebral block (PVB). The goal was to see which provides better pain control …
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Which nerve block wins for knee surgery pain? new study reveals answer
Symptom relief CompletedThis study compared two types of nerve blocks—genicular nerve block and IPACK block—for managing pain after knee arthroscopy. Fifty adults aged 20-60 who had knee surgery took part. The goal was to see which method provides better pain relief and reduces the need for opioids in t…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 06, 2026 16:01 UTC
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Can a common antidepressant ease Post-Surgery pain?
Symptom relief CompletedThis study looked at whether giving the antidepressant mirtazapine before and after mastectomy surgery can reduce pain. 62 women scheduled for mastectomy took part. The main goal was to see if it lowered the amount of morphine needed in the first 24 hours and improved pain scores…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 05, 2026 11:54 UTC
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Pre-Surgery prep cuts complications in gynecologic cancer patients
Symptom relief CompletedThis study tested a multimodal prehabilitation program (exercise, education, and support before surgery) in 140 women with newly diagnosed gynecologic cancer. The goal was to see if it reduces complications, pain, and hospital stay after surgery compared to standard care. Results…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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New nerve block combo aims to slash Post-Surgery pain
Symptom relief CompletedThis study tested if adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. It involved 60 women and measured how much morphine they needed for pain relief in the first two days after their operati…
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 13, 2026 20:18 UTC
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Ultrasound score may predict best surgery for dangerous pregnancy condition
Knowledge-focused CompletedThis study looked at 154 pregnant women with placenta accreta (a condition where the placenta grows too deeply into the womb) to see if an ultrasound scoring system could help doctors choose the safest type of surgery. The goal was to predict whether a woman could have fertility-…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:24 UTC
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Can a simple ultrasound predict Baby's future in preeclampsia?
Knowledge-focused CompletedThis study looked at whether special ultrasound measurements of the baby's kidney blood flow and the placenta could predict health problems in newborns of mothers with preeclampsia. Researchers compared 114 pregnant women with and without preeclampsia. The goal was to see if thes…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:22 UTC
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New blood test could help doctors manage postpartum bleeding
Knowledge-focused CompletedThis study looked at 90 women who had severe bleeding after childbirth (postpartum hemorrhage). Researchers used a device called Sonoclot to quickly measure how well their blood was clotting. The goal was to see if this test could help doctors spot clotting problems early and gui…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:21 UTC
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Tummy tucks after weight loss surgery: do they stop the regain?
Knowledge-focused CompletedThis study looked at 60 people who had sleeve gastrectomy (weight loss surgery) and then got body contouring surgery to remove extra skin and fat. Researchers wanted to see if the contouring surgery helped prevent weight regain and how it affected metabolism. They measured weight…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:18 UTC
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Blood clues: simple tests may forecast myeloma survival
Knowledge-focused CompletedThis study checked if three simple blood measurements—blood thickness, albumin/fibrinogen ratio, and red cell distribution width—can help predict how newly diagnosed multiple myeloma patients will do over one year. Researchers followed 48 patients for a year after diagnosis, comp…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:17 UTC
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Knee surgery showdown: which cut spares your blood vessels?
Knowledge-focused CompletedThis study looked at 40 adults with knee arthritis to compare two types of knee realignment surgery (open wedge high tibial osteotomy). The goal was to see which technique keeps the popliteal blood vessels safer by measuring the distance between the vessels and the bone using CT …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:10 UTC
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Nurse training cuts infection risk in kidney stone surgery
Knowledge-focused CompletedThis study tested a teaching program to improve nurses' knowledge and practice of infection control for patients having a type of kidney stone surgery called percutaneous nephrolithotomy. Thirty nurses who provide care before, during, and after the surgery took part. The goal was…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 17, 2026 09:08 UTC
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Liver cirrhosis patients monitored for 90-day survival
Knowledge-focused CompletedThis study looked at 100 adults with liver cirrhosis who were admitted to the hospital. The goal was to track how many patients died within 90 days and find out what factors increased their risk. No new treatments were tested; instead, researchers collected data to better underst…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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New ultrasound test may predict Baby's breathing trouble before birth
Knowledge-focused CompletedThis study looked at whether measuring blood flow in the lungs of unborn babies using ultrasound can help predict breathing problems after birth. Researchers studied 86 pregnant women with severe preeclampsia between 28 and 37 weeks of pregnancy. The goal was to see if these meas…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Researchers map gum pigmentation in egyptians
Knowledge-focused CompletedThis study looked at gum color in 70 healthy Egyptian adults to see how common dark patches are and how they spread. Researchers used special scales to measure the color and pattern of pigmentation. The goal was simply to learn more about normal gum color in this population, not …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Who seeks addiction treatment? new study reveals key traits
Knowledge-focused CompletedThis study looked at the personal and social backgrounds of 106 people admitted for addiction treatment at Assiut University Hospital. Researchers collected information on age, gender, job status, and the types of substances used. The goal was to better understand who is affected…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New combo test may spot vocal cord issues better
Knowledge-focused CompletedThis study looked at 100 men with irregular patches on their vocal folds. Researchers combined a special camera exam (laryngostroboscopy) with standard tissue analysis to see if this approach improves diagnosis. They also checked if a gene called SOX2 could help identify the prob…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 08, 2026 12:09 UTC
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Stomach bug study reveals antibiotic weaknesses
Knowledge-focused CompletedThis study looked at 100 adults with H. pylori infection to find out which antibiotics work best and which bacterial genes cause resistance or cancer risk. Researchers took stomach samples during endoscopy to test the bacteria and check for specific genes. The goal was to underst…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 06, 2026 16:03 UTC
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New ICU score may help predict outcomes for liver patients
Knowledge-focused CompletedThis study looked at 150 adults with liver cirrhosis admitted to the intensive care unit (ICU). Researchers calculated a special score (ICCO) using blood tests to see if it could predict which patients would survive. The goal is to help doctors make better decisions for criticall…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 06, 2026 16:03 UTC
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New genetic clues may explain why some women miscarry repeatedly
Knowledge-focused CompletedThis study aimed to find new biological reasons for recurrent miscarriage in women with no known cause. Researchers measured specific molecules (microRNA 410 and BIRC7) in 86 women aged 20-30 who had two or more miscarriages. The goal was to better understand the disease, not to …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC