Which Nerve-Blocking technique offers better knee pain relief?

NCT ID NCT05591768

Completed Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This trial compares two ways of using radiofrequency energy to block knee nerves in people with osteoarthritis-related knee pain that hasn't improved with other treatments. One method uses a single probe (monopolar), the other uses two probes (bipolar). The study will measure pain relief, procedural discomfort, complications, and how long the procedure takes, aiming to see if the bipolar approach is more effective and less painful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiofrequency ablation of genicular nerves (monopolar vs bipolar)
What this could lead to: If successful, this could identify a more effective and less painful nerve-blocking technique to ease chronic knee osteoarthritis pain, potentially helping people avoid surgery.
What could go wrong: The trial is relatively small and early-stage, so results may not apply broadly. Radiofrequency ablation carries risks like temporary nerve damage, bruising, or infection, and pain relief may not last.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Assuit University hospitals

Asyut, Egypt

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