Which knee implant feels more natural? a trial puts two designs to the test

NCT ID NCT07757581

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial compares two types of knee replacement implants: one that keeps the posterior cruciate ligament (CR) and one that does not (PS). Both are implanted using a computer-assisted personalized technique that aims to restore the knee's natural alignment. The study includes 140 adults with knee osteoarthritis who need a total knee replacement. The main goal is to see if patients report similar joint awareness and function 24 months after surgery, regardless of which implant they receive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Knee replacement surgery using either a cruciate-retaining (CR) or posterior-stabilized (PS) prosthesis, implanted with a computer-assisted personalized technique.
What this could lead to
If successful, this could help surgeons choose the best implant design for personalized knee replacement, potentially improving patient satisfaction and joint function.
What could go wrong
This is a single-center trial, and results may not apply to all patients or surgical settings. The study is not designed to prove one implant is superior, only to check if they are similar.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Groupe hospitalier Diaconesses Croix Saint Simon

    Paris, 75020, France

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