Can glue and barbed sutures beat staples for joint surgery wounds?

NCT ID NCT07749495

Not yet recruiting Disease control Sponsor: Groupe Hospitalier Diaconesses Croix Saint-Simon Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether closing surgical wounds with barbed sutures and skin glue leads to better healing than traditional staples or monofilament sutures in people undergoing hip or knee replacement. About 400 adults will be randomly assigned to one of the closure methods, and the main goal is to see if the wound heals without complications like infection, bleeding, or opening within the first two weeks after surgery. The study also looks at scar appearance and severity of any wound issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: barbed sutures and skin glue
What this could lead to: If effective, this technique could reduce wound complications and improve scar appearance after joint replacement, potentially becoming a preferred closure method.
What could go wrong: This is a comparative study, not a cure. Results may vary by patient, and the technique might not show significant benefits over standard methods. Risks include infection or wound healing issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Surgical Wound

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP ARTHROPLASTY KNEE ARTHROPLASTY SURGICAL WOUND

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Other studies related to the condition(s) this trial covers.