Nutrition boost may ease radiation side effects in head and neck cancer
NCT ID NCT06477341
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study tested whether active nutritional support with high-protein drinks can reduce the occurrence of painful mouth sores (mucositis) and improve quality of life in head and neck cancer patients undergoing radiotherapy. The study enrolled 47 newly diagnosed adults and tracked their nutritional status using body mass index. The goal was to see if better nutrition during treatment helps manage side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-protein nutritional supplements (e.g., Ensure milk)
- What this could lead to
- If effective, this approach could help reduce painful mouth sores and improve quality of life during radiotherapy for head and neck cancer.
- What could go wrong
- This is a small, completed study with only 47 participants, so results may not apply broadly. Nutritional support alone may not significantly reduce mucositis.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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47 people
The number who actually took part.
- Started
-
Jan 2023
- Finished
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Sep 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * head and neck cancer patients with age \>18 * Newly diagnosed head and neck cancer patients * histological proven HNC cancer * head and neck cancer patients treated with radiotherapy or chemo radiotherapy Exclusion Criteria: * Advanced and Metastatic head and neck cancer patients * head and neck cancer patients treated with chemotherapy only
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Reham mohamed
Asyut, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Experimental pill HG146 put to the test against rare head and neck cancer
- Can a dental assistant keep cancer Patients' mouths healthier during radiation?
- Why do Non-Smokers get head and neck cancer? scientists probe tumor DNA
- Re-irradiation plus cetuximab targets head and neck tumors that return
- Sharper tumor maps: PET scans could tighten radiation beams
- Shorter radiation course tested for advanced head and neck cancer