HEAD AND NECK NEOPLASMS

This study is testing a new, less intense treatment plan for frail seniors aged 65+ with head and neck cancer. The goal is to see if a tailored combination of chemotherapy and/or immunotherapy, followed by radiation, can effectively control the cancer while being easier for older…

This study aims to make a common chemotherapy treatment safer by using a genetic test. It will check if adjusting the drug dose based on a patient's specific gene (DPYD) reduces severe side effects compared to the standard dose. The trial includes 100 adults with cancers like col…

This study is testing a new approach for treating advanced head and neck cancer that has returned or spread. Researchers want to see if using a simple blood test to measure tumor DNA can help decide when to add short bursts of chemotherapy to standard immunotherapy. The goal is t…

This study is testing whether using a lower dose of radiation, combined with chemotherapy and planned surgery, can effectively control certain head and neck cancers. The goal is to see if this approach works while potentially reducing treatment side effects. It is for adults with…

This is the first study in humans testing a new cancer drug called AZD9592. Researchers want to find safe doses and see if it helps control advanced cancers like lung, head/neck, and colorectal tumors. The study will test AZD9592 alone and combined with other cancer treatments in…

This early-stage study is testing a new combination of three drugs for people with advanced head and neck cancer that has returned or spread. The main goal is to find the safest and most effective dose of the new drug, Zanzalintinib, when given with two existing cancer drugs. Res…

This program offers a special type of PET scan to children and young adults with known or suspected cancers in the brain, spine, or head/neck area. The scan uses a small, safe amount of a radioactive tracer that may help doctors see the cancer more clearly. The goal is to provide…

This study is testing if a supervised heavy weight lifting program is practical and helpful for people who have survived head and neck cancer. It will compare 60 survivors doing 12 weeks of heavy lifting against a group receiving usual care. The main goal is to see if the program…

This study is testing if a treatment using medical ozone gas can help reduce the severity of painful mouth sores caused by chemotherapy or radiation, especially for head and neck cancer patients. Fifty participants will be randomly assigned to receive either ozone therapy alone o…

This study is testing whether a treatment called photobiomodulation (a type of low-level laser light therapy) can help improve dry mouth and overall quality of life for people who have survived head and neck cancer after radiation therapy. Researchers will enroll 60 participants …

This study aims to create a large collection of biological samples to help scientists better understand disorders affecting hearing, balance, voice, speech, and swallowing. Researchers will collect leftover tissue from medical procedures, plus blood, saliva, and cheek swabs from …

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …