One drop, many cancers? a rapid test aims to spot cancer signals in blood, urine, or saliva

NCT ID NCT07741435

Recruiting now Diagnosis Sponsor: Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study evaluates a rapid test called Methylscape that measures DNA methylation patterns in body fluids like blood, urine, or saliva. The goal is to see if it can detect a cancer signal and even predict where the cancer started, using a single sample. Researchers will compare results from about 3,250 adults—some with biopsy-confirmed solid tumors and some cancer-free—to measure the test's accuracy. If it works, this could become a low-cost tool for catching multiple cancer types early and monitoring for relapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Methylscape DNA methylation assay (a rapid diagnostic test measuring DNA methylation patterns in body fluids)
What this could lead to: If successful, this could lead to a simple, affordable blood, urine, or saliva test that detects multiple cancer types early and identifies where the cancer started, potentially improving survival odds.
What could go wrong: This is an observational study, not a treatment trial, so it won't cure cancer directly. The test may not be accurate enough in real-world settings, and results from this Colombian population may not apply globally.

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Conditions

The condition(s) this trial relates to.

benign urinary system neoplasm breast neoplasm cervical cancer colorectal neoplasm gastric neoplasm head and neck neoplasm Head and Neck Neoplasms lung neoplasm neoplasm Neoplasm Recurrence, Local Neoplasm, Residual urinary system neoplasm Uterine Cervical Neoplasms uterine cervix neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS COLORECTAL NEOPLASMS EARLY DETECTION OF CANCER HEAD AND NECK NEOPLASMS LUNG NEOPLASMS NEOPLASM RECURRENCE, LOCAL NEOPLASMS SOLID TUMOR STOMACH NEOPLASMS UROLOGIC NEOPLASMS UTERINE CERVICAL NEOPLASMS

Contacts and locations

Locations

Fundación CTIC Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo
RECRUITING

Bogotá, Bogota D.C., 110131, Colombia

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