UTERINE CERVICAL NEOPLASMS

This trial tests a new drug, UCB4594, designed to help the immune system attack cancer cells by targeting a protein called HLA-G found on many tumors. It is for people with advanced solid cancers that have not responded to standard treatments. The study aims to find the safest do…

This study tests whether a drug that boosts the immune system (dostarlimab), alone or with a drug that blocks blood vessel growth (bevacizumab), works better than standard chemotherapy for women whose gynecological clear cell cancer has come back. About 198 women will be randomly…

This early-stage trial tests a drug called sigvotatug vedotin, alone or with other medicines, in people with advanced solid tumors like lung, head and neck, or breast cancer. The main goal is to check safety and find the right dose. About 1,000 participants will join this study t…

This study tests a new drug called LY4170156 in people with advanced solid tumors, such as ovarian, lung, and breast cancers. The drug is designed to target and kill cancer cells while sparing healthy ones. The trial has two parts: first to find the safest dose, then to see how w…

This study is testing a new, low-cost screening method for cervical cancer that uses artificial intelligence to analyze digital images of the cervix. The goal is to see if this AI tool, called Automated Visual Evaluation (AVE), can accurately detect precancerous changes without n…

This study looks at MRI scans from 120 women with advanced cervical cancer to create a model that predicts how well they will respond to standard chemoradiotherapy. The goal is to identify women who might not benefit from standard treatment early, so they can consider other optio…

This study follows 250 women living with HIV in Zimbabwe who have been treated for cervical pre-cancer. Researchers want to understand why some women's pre-cancer returns after treatment and how to better monitor them. Participants will have regular check-ups and tests over two y…

This study tests whether an interactive video program, combined with help from a community health worker, can increase cervical cancer screening among African American women who are overdue for screening. About 288 women will be randomly assigned to receive either the interactive…