New drug targets Hard-to-Treat cancers in early trial

NCT ID NCT06400472

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This study tests a new drug called LY4170156 in people with advanced solid tumors, such as ovarian, lung, and pancreatic cancers. The drug is designed to target and kill cancer cells that have a specific marker (folate receptor alpha). The trial has two parts: first, finding the safest dose, and then testing how well it works. About 495 participants will take part, and the study will last up to 4 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Institute Hospital of JFCR

    RECRUITING

    Tokyo, 135-8550, Japan

  • Cancer Research SA

    RECRUITING

    Adelaide, 5000, Australia

  • Centre Leon Berard

    RECRUITING

    Lyon, 69373, France

  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • HonorHealth

    RECRUITING

    Scottsdale, Arizona, 85258, United States

  • Hospital Clinico Universitario de Valencia

    RECRUITING

    Valencia, 46010, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Icon Cancer Centre South Brisbane

    RECRUITING

    QLD, 4101, Australia

  • Institut de Cancerologie de l'Ouest - site St-Herblain

    RECRUITING

    Saint-Herblain, 44805, France

  • Istituto Clinico Humanitas

    RECRUITING

    Rozzano, 20089, Italy

  • Istituto Europeo di Oncologia

    RECRUITING

    Milan, 20141, Italy

  • NYU Langone Health - Long Island

    RECRUITING

    Mineola, New York, 11501, United States

  • National Cancer Center

    RECRUITING

    Goyang-si Gyeonggi-do, 10408, South Korea

  • National Cancer Center Hospital

    RECRUITING

    Tokyo, 104-0045, Japan

  • New York University (NYU) Clinical Cancer Center

    RECRUITING

    New York, New York, 10016, United States

  • Oncopole Claudius Regaud

    RECRUITING

    Toulouse, 31059, France

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • Shizuoka Cancer Center

    RECRUITING

    Shizuoka, 411-8777, Japan

  • South Texas Accelerated Research Therapeutics (START) Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • The Ohio State University (OSU) Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The University of Texas - MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030-4000, United States

  • University of California, San Diego (UCSD) - Moores Cancer Center

    RECRUITING

    La Jolla, California, 92037, United States

Conditions

Explore the condition pages connected to this study.