TRIPLE NEGATIVE BREAST NEOPLASMS

This study is testing whether combining two existing drugs, bicalutamide and abemaciclib, can help control a hard-to-treat form of advanced breast cancer. It is for women whose cancer has a specific marker (androgen receptor positive) and has worsened after at least one prior tre…

This study is testing a new combination of two cancer drugs, disitamab vedotin and tucatinib, for people with advanced or spreading breast or stomach cancer. The main goals are to find a safe and effective dose and to see if the combination can shrink tumors. It is for people who…

This large study is testing whether adding a new targeted drug called sacituzumab tirumotecan to standard chemotherapy and immunotherapy works better before surgery for certain aggressive, early-stage breast cancers. Researchers want to see if this three-drug combination helps el…

This study is testing whether a new targeted drug called sacituzumab tirumotecan works better alone or combined with pembrolizumab compared to standard chemotherapy for advanced triple-negative breast cancer. It will involve 1,000 people with previously untreated cancer that has …

This is the first study in people to test a new oral drug called NKT3964. It aims to see if the drug is safe and can help control advanced cancers that have spread and stopped responding to standard treatments. The study will enroll adults with specific advanced solid tumors, inc…

This study is for people with triple-negative breast cancer who still have cancer cells after initial chemo-immunotherapy and surgery. It tests if adding the pill capecitabine to the immunotherapy pembrolizumab after surgery is better at preventing the cancer from coming back tha…

This is a first-in-human study to test the safety and find the right dose of a new drug called PF-08046054/SGN-PDL1V for people with advanced solid tumors. It will be tested alone and in combination with another cancer drug, pembrolizumab. The study is recruiting 714 participants…

This study is testing a new drug called BMS-986340 to see if it is safe and can help control advanced cancers. It will be given alone or combined with two other cancer drugs to about 950 people whose cancers have grown despite standard treatments. The main goal is to find the rig…

This is the first study in people to test a new targeted cancer drug called LY4170156. It aims to find a safe dose and see if it can help control advanced cancers, including ovarian, lung, breast, and pancreatic cancers. The study will also test the drug in combination with other…