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New hope for aggressive breast cancer: drug combo trial launches

NCT ID NCT06841354

Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 15 times

Summary

This study tests whether a new drug, sacituzumab tirumotecan (Sac-TMT), given alone or with pembrolizumab, helps people with advanced triple-negative breast cancer live longer or keep their cancer from growing. About 1,000 adults whose cancer has spread and who have not had prior treatment for advanced disease will be randomly assigned to one of these experimental treatments or standard chemotherapy. The goal is to compare how well these options work and how safe they are.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

May 2030

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Has locally recurrent unresectable or metastatic TNBC that cannot be treated with curative intent * Has not received systemic treatment for locally recurrent unresectable or metastatic breast cancer * Participants previously treated for early-stage breast cancer must have completed all prior therapy for early-stage breast cancer with curative intent at least 6 months before the first disease recurrence * Is a candidate for treatment with pembrolizumab and one of the TPC options: paclitaxel or nab-paclitaxel or gemcitabine + carboplatin * Participants who have AEs due to previous anticancer therapies must have recovered to ≤Grade 1 or baseline with the exception of alopecia or vitiligo. Participants with endocrine-related AEs who are adequately treated with hormone replacement are eligible * Participants who are hepatitis B surface antigen (HBsAg) positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks, and have undetectable HBV viral load * Participants with history of hepatitis C virus (HCV) infection are eligible if HCV viral load is undetectable Exclusion Criteria: The main exclusion criteria include but are not limited to the following: * Has breast cancer amenable to treatment with curative intent * Has TNBC with evaluable tumor programmed death ligand 1 (PD-L1) expression at combined positive score (CPS) ≥10 * Has received prior systemic therapy for treatment of locally recurrent unresectable or metastatic breast cancer * Has Grade ≥2 peripheral neuropathy * Has history of documented severe dry eye syndrome, severe Meibomian gland disease and/or blepharitis, or severe corneal disease that prevents/delays corneal healing * Has active inflammatory bowel disease requiring immunosuppressive medication or previous history of inflammatory bowel disease * Has uncontrolled, significant cardiovascular disease or cerebrovascular disease * Has skin only metastatic disease * Has advanced/metastatic, symptomatic visceral spread at risk of rapidly evolving into life-threatening complications * Human immunodeficiency virus (HIV)-infected participants with a history of Kaposi's sarcoma and/or Multicentric Castleman's Disease * Has known additional malignancy that is progressing or has required active treatment within the past 5 years * Has known active central nervous system (CNS) metastases and/or carcinomatous meningitis. Participants with previously treated brain metastases may participate provided they are radiologically stable * Active autoimmune disease that has required systemic treatment in the past 2 years. Replacement therapy (eg, thyroxine, insulin, or physiologic corticosteroid) is allowed * Has a history of (noninfectious) pneumonitis/interstitial lung disease (ILD) that required steroids, has current pneumonitis/ILD, or has suspected ILD or pneumonitis that cannot be ruled out by standard diagnostic assessments * Concurrent active Hepatitis B (defined as HBsAg positive and/or detectable HBV deoxyribonucleic acid (DNA)) and Hepatitis C virus (HCV) (defined as anti-HCV antibody (Ab) positive and detectable HCV ribonucleic acid (RNA)) infection * History of stem cell/solid organ transplant * Has not adequately recovered from major surgery or has ongoing surgical complications

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Triple negative breast neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    267 sites in 35 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AZ Maria Middelares ( Site 3103)

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • Aarhus Universitets hospital ( Site 3204)

    RECRUITING

    Aarhus, Central Jutland, 8200, Denmark

  • Adana Medical Park Seyhan Hastanesi ( Site 4804)

    RECRUITING

    Adana, 01140, Turkey (Türkiye)

  • AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0007)

    RECRUITING

    Altamonte Springs, Florida, 32701, United States

  • Affiliated Tumor Hospital of Xinjiang Medical University ( Site 5006)

    RECRUITING

    Ürümqi, Xinjiang, 830011, China

  • Aichi Cancer Center ( Site 5117)

    RECRUITING

    Nagoya, Aichi-ken, 464-8681, Japan

  • Akita University Hospital ( Site 5115)

    RECRUITING

    Akita, 010-8543, Japan

  • Allina Health Cancer Institute ( Site 0069)

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

  • Ankara Bilkent Şehir Hastanesi ( Site 4801)

    RECRUITING

    Ankara, 06800, Turkey (Türkiye)

  • Aretaieio Hospital ( Site 3900)

    RECRUITING

    Athens, Attica, 115 28, Greece

  • Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 4604)

    RECRUITING

    Novara, 28100, Italy

  • Bialostockie Centrum Onkologii ( Site 3810)

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-027, Poland

  • Biocenter ( Site 2009)

    RECRUITING

    Concepción, Biobio, 4070196, Chile

  • Blacktown Hospital ( Site 5500)

    RECRUITING

    Blacktown, New South Wales, 2148, Australia

  • Bowen Icon Cancer Centre ( Site 5601)

    RECRUITING

    Crofton Downs, Wellington Region, 6035, New Zealand

  • Bradfordhill ( Site 2001)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

  • Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 3408)

    RECRUITING

    Budapest, Pest County, 1145, Hungary

  • Békés Vármegyei Központi Kórház Pándy Kálmán Tagkórház-Megyei Onkológiai Centrum ( Site 3405)

    RECRUITING

    Gyula, Bekes County, 5700, Hungary

  • CENTRE LEON BERARD ( Site 3004)

    RECRUITING

    Lyon, Auvergne-Rhône-Alpes, 69373, France

  • CIO - Centro de Inmuno-Oncología de Occidente ( Site 2504)

    RECRUITING

    Guadalajara, Jalisco, 44630, Mexico

  • CIUSSS- saguenay-Lac-Saint-Jean ( Site 0213)

    RECRUITING

    Chicoutimi, Quebec, G7H 5H6, Canada

  • COI Centro Oncologico Internacional S.A.P.I. de C.V. ( Site 2514)

    RECRUITING

    Mexico City, Mexico City, 04700, Mexico

  • COMMUNAL NONPROFIT ENTERPRISE CLINICAL CENTER OF ONCOLOGY, HEMATOLOGY, TRANSPLANTOLOGY AND PALLIATI ( Site 4409)

    RECRUITING

    Cherkasy, Cherkasy Oblast, 18009, Ukraine

  • Cabinet Medical Oncomed ( Site 4704)

    RECRUITING

    Timișoara, Timiș County, 300239, Romania

  • Cancer & Hematology Centers of Western Michigan ( Site 0026)

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Cancer Institute Hospital of JFCR ( Site 5102)

    RECRUITING

    Koto, Tokyo, 135-8550, Japan

  • Caritas Klinikum Saarbruecken St. Theresia ( Site 4301)

    RECRUITING

    Saarbrücken, Saarland, 66113, Germany

  • Centre Henri Becquerel ( Site 3001)

    RECRUITING

    Rouen, Seine-Maritime, 76038, France

  • Centre Hospitalier de l'Université de Montréal ( Site 0208)

    RECRUITING

    Montreal, Quebec, H2X 3E4, Canada

  • Centro Cancerologico del Caribe LTD ( Site 2209)

    RECRUITING

    Barranquilla, Atlántico, 080002, Colombia

  • Centro Oncologico de Alta Especialidad, S.C. ( Site 2509)

    RECRUITING

    Mexico City, Mexico City, 06140, Mexico

  • Centro Potosino de Investigación Médica ( Site 2512)

    RECRUITING

    San Luis Potosí City, 78250, Mexico

  • Centro de Investigacion Clinica de Oaxaca ( Site 2503)

    RECRUITING

    Oaxaca City, Oaxaca, 68020, Mexico

  • Centro de Investigación Oncológica Galerías SC ( Site 2511)

    RECRUITING

    Aguascalientes, 20124, Mexico

  • Centrul Medical Neolife- Baneasa ( Site 4706)

    RECRUITING

    Bucharest, 077190, Romania

  • Centrul de Oncologie "Sfântul Nectarie" ( Site 4702)

    RECRUITING

    Craiova, Dolj, 200542, Romania

  • Centrum Onkologii im prof Franciszka Lukaszczyka ( Site 3802)

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland

  • Chang Gung Memorial Hospital ( Site 5302)

    RECRUITING

    Taoyuan, 333, Taiwan

  • Chongqing University Three Gorges Hospital ( Site 5020)

    COMPLETED

    Chongqing, Chongqing Municipality, 404000, China

  • City of Hope ( Site 0097)

    RECRUITING

    Duarte, California, 91010, United States

  • City of Hope Lennar Foundation Cancer Center ( Site 0099)

    RECRUITING

    Irvine, California, 92618, United States

  • Clinica Viedma ( Site 2403)

    RECRUITING

    Viedma, Río Negro Province, R8500ACE, Argentina

  • Clinique Francois Chenieux ( Site 3006)

    RECRUITING

    Limoges, Haute-Vienne, 87000, France

  • Clínica Internacional - Sede San Borja ( Site 2604)

    RECRUITING

    Lima, 15036, Peru

  • Clínica UC San Carlos de Apoquindo ( Site 2008)

    RECRUITING

    Santiago, Region M. de Santiago, 7620002, Chile

  • Communal Non-Commercial Enterprise Prykarpatski Clinical Oncological Center of Ivano-Frankivsk Regio ( Site 4401)

    RECRUITING

    Ivano-Frankivsk, Ivano-Frankivsk Oblast, 76018, Ukraine

  • Comprehensive Cancer Centers of Nevada ( Site 0015)

    RECRUITING

    Las Vegas, Nevada, 89106, United States

  • Cross Cancer Institute ( Site 0216)

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

  • Debreceni Egyetem Klinikai Kozpont ( Site 3411)

    RECRUITING

    Debrecen, 4032, Hungary

  • Deventer Ziekenhuis ( Site 4503)

    RECRUITING

    Deventer, Overijssel, 7416 SE, Netherlands

  • ETZ Elisabeth ( Site 4504)

    RECRUITING

    Tilburg, North Brabant, 5022 GC, Netherlands

  • Ege Universitesi Hastanesi ( Site 4803)

    RECRUITING

    Bornova, İzmir, 35100, Turkey (Türkiye)

  • Erasmus Medisch Centrum ( Site 4505)

    RECRUITING

    Rotterdam, South Holland, 3015 GD, Netherlands

  • European Interbalkan Medical Center ( Site 3901)

    RECRUITING

    Thessaloniki, 570 01, Greece

  • FALP ( Site 2000)

    RECRUITING

    Santiago, Region M. de Santiago, 7500921, Chile

  • FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 2203)

    RECRUITING

    Bogotá, Bogota D.C., 110131, Colombia

  • Faculty of Medicine - Khon Kaen University ( Site 5802)

    RECRUITING

    Khon Kaen, 40002, Thailand

  • Faculty of Medicine Siriraj Hospital ( Site 5800)

    RECRUITING

    Bangkoknoi, Bangkok, 10700, Thailand

  • Fakultni Thomayerova nemocnice ( Site 3506)

    RECRUITING

    Prague, 140 59, Czechia

  • Fakultni nemocnice Olomouc ( Site 3502)

    RECRUITING

    Olomouc, 77900, Czechia

  • Fakultni nemocnice Ostrava ( Site 3505)

    RECRUITING

    Ostrava - Poruba, Moravian-Silesian Region, 708 52, Czechia

  • Fakultni nemocnice v Motole ( Site 3503)

    RECRUITING

    Prague, 150 06, Czechia

  • Filios Alta Medicina ( Site 2506)

    RECRUITING

    Monterrey, Nuevo León, 64460, Mexico

  • Florida Cancer Specialists - East ( Site 7000)

    RECRUITING

    West Palm Beach, Florida, 33401, United States

  • Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4601)

    RECRUITING

    Milan, 20133, Italy

  • Fred Hutchinson Cancer Center ( Site 0042)

    RECRUITING

    Seattle, Washington, 98109, United States

  • Fukushima Medical University Hospital ( Site 5101)

    RECRUITING

    Fukushima, 960-1295, Japan

  • Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 2307)

    RECRUITING

    Barretos, São Paulo, 14784-400, Brazil

  • Fundacion Centro Oncologico de Integración Regional ( Site 2400)

    RECRUITING

    Mendoza, M5500AYB, Argentina

  • Fundacion Estudios Clinicos ( Site 2405)

    RECRUITING

    Rosario, Santa Fe Province, S2000DEJ, Argentina

  • Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 2301)

    RECRUITING

    São Jose Do Rio Preto, São Paulo, 15090-000, Brazil

  • Gazi University Health Research and Application Center Gazi Hospital ( Site 4805)

    RECRUITING

    Ankara, 06560, Turkey (Türkiye)

  • General University Hospital of Larissa, Oncology Clinic ( Site 3902)

    RECRUITING

    Larissa, Thessaly, 411 10, Greece

  • Groupe Hospitalier Paris Saint Joseph ( Site 3010)

    RECRUITING

    Paris, 75014, France

  • Grupo Médico ASSET ( Site 2507)

    RECRUITING

    Mexico City, Mexico City, 03100, Mexico

  • Guangxi Medical University Affiliated Tumor Hospital. ( Site 5008)

    RECRUITING

    Nanning, Guangxi, 530201, China

  • HELIOS Klinikum Berlin-Buch ( Site 4303)

    RECRUITING

    Berlin, 13125, Germany

  • HIA Sainte Anne ( Site 3007)

    RECRUITING

    Toulon, Var, 83800, France

  • HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 4104)

    RECRUITING

    Seville, Andalusia, 41013, Spain

  • Hacettepe Universite Hastaneleri ( Site 4800)

    RECRUITING

    Ankara, 06230, Turkey (Türkiye)

  • Harbour Cancer & Wellness ( Site 5600)

    RECRUITING

    Newmarket, Auckland, 1023, New Zealand

  • Hattiesburg Clinic Hematology/Oncology ( Site 0104)

    RECRUITING

    Hattiesburg, Mississippi, 39401, United States

  • Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 3301)

    RECRUITING

    Helsinki, Uusimaa, 00029, Finland

  • Henan Cancer Hospital ( Site 5001)

    RECRUITING

    Zhengzhou, Henan, 450008, China

  • Herlev og Gentofte Hospital. ( Site 3205)

    RECRUITING

    Copenhagen, Capital Region, 2730, Denmark

  • Higiea Oncologia ( Site 2505)

    RECRUITING

    Mexico City, Mexico City, 11810, Mexico

  • Hiroshima City Hiroshima Citizens Hospital ( Site 5113)

    RECRUITING

    Hiroshima, 730-8518, Japan

  • Hokkaido University Hospital ( Site 5100)

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Holy Cross Hospital ( Site 0091)

    RECRUITING

    Silver Spring, Maryland, 20910, United States

  • Hopital Du Saint-Sacrement ( Site 0210)

    RECRUITING

    Québec, Quebec, G1S 4L8, Canada

  • Hospital Beata María Ana ( Site 4105)

    RECRUITING

    Madrid, 28007, Spain

  • Hospital Clinico San Carlos ( Site 4100)

    RECRUITING

    Madrid, Madrid, Comunidad de, 28040, Spain

  • Hospital General Universitario de Valencia ( Site 4102)

    RECRUITING

    Valencia, Valenciana, Comunitat, 46014, Spain

  • Hospital Italiano de Cordoba ( Site 2406)

    RECRUITING

    Córdoba, Córdoba Province, X5004BAL, Argentina

  • Hospital Militar Central Coronel Luis Arias Schereiber ( Site 2603)

    RECRUITING

    Lima, 15076, Peru

  • Hospital Nossa Senhora da Conceição ( Site 2302)

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 91350-200, Brazil

  • Hospital Provincial del Centenario ( Site 2410)

    RECRUITING

    Rosario, Santa Fe Province, S2002KDR, Argentina

  • Hospital Universitario Ramon y Cajal ( Site 4103)

    RECRUITING

    Madrid, 28034, Spain

  • Hospital de Câncer de Recife ( Site 2300)

    RECRUITING

    Recife, Pernambuco, 50040-000, Brazil

  • Hunan Cancer Hospital ( Site 5002)

    RECRUITING

    Changsha, Hunan, 410013, China

  • Hôpital Européen Georges Pompidou ( Site 3011)

    RECRUITING

    Paris, 75015, France

  • IBCC - Núcleo de Pesquisa e Ensino ( Site 2306)

    RECRUITING

    São Paulo, 04014-002, Brazil

  • IC La Serena Research ( Site 2007)

    RECRUITING

    La Serena, Coquimbo Region, 1720430, Chile

  • ICO L Hospitalet ( Site 4101)

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • IMAT S.A.S ( Site 2202)

    ACTIVE_NOT_RECRUITING

    Montería, Departamento de Córdoba, 230002, Colombia

  • IPOR Instituto Peruano de Oncología & Radioterapia ( Site 2601)

    RECRUITING

    Lima, 15036, Peru

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 4605)

    RECRUITING

    Bologna, 40138, Italy

  • IRCCS Ospedale San Raffaele ( Site 4600)

    RECRUITING

    Milan, 20132, Italy

  • Institut De Cancerologie De L Ouest ( Site 3003)

    RECRUITING

    Saint-Herblain, Loire-Atlantique, 44805, France

  • Institut Jean Godinot ( Site 3002)

    RECRUITING

    Reims, Marne, 51100, France

  • Institut Regional du Cancer Montpellier ( Site 3009)

    RECRUITING

    Montpellier, Herault, 34298, France

  • Instituto Alexander Fleming ( Site 2402)

    RECRUITING

    Mar del Plata, Buenos Aires, C1426ANZ, Argentina

  • Instituto de Investigaciones Clinicas Mar del Plata ( Site 2401)

    RECRUITING

    Mar del Plata, Buenos Aires, B7600FZN, Argentina

  • Institutul Oncologic Cluj ( Site 4701)

    RECRUITING

    Cluj-Napoca, Cluj, 400015, Romania

  • Ironwood Cancer & Research Centers ( Site 0036)

    RECRUITING

    Chandler, Arizona, 85224, United States

  • Istituto Nazionale Tumori Regina Elena ( Site 4607)

    RECRUITING

    Rome, Roma, 00128, Italy

  • Istituto Oncologico Veneto IRCCS ( Site 4603)

    RECRUITING

    Padova, 35128, Italy

  • Jewish General Hospital ( Site 0203)

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Jiangsu Province Hospital ( Site 5009)

    RECRUITING

    Nanjing, Jiangsu, 210029, China

  • Jilin Province Tumor Hospital ( Site 5040)

    RECRUITING

    Changchun, Jilin, 130015, China

  • Jinan Central Hospital ( Site 5031)

    RECRUITING

    Jinan, Shandong, 250013, China

  • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0082)

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Juntendo University Hospital ( Site 5104)

    RECRUITING

    Bunkyo, Tokyo, 113-8431, Japan

  • Kanagawa Cancer Center ( Site 5106)

    RECRUITING

    Yokohama, Kanagawa, 241-8515, Japan

  • Kanazawa Medical University Hospital ( Site 5127)

    RECRUITING

    Kahoku-gun, Ishikawa-ken, 920-0293, Japan

  • Kelsey-Seybold Clinic ( Site 0040)

    RECRUITING

    Houston, Texas, 77025, United States

  • Kelsey-Seybold Clinic - North Houston Campus ( Site 0096)

    RECRUITING

    Houston, Texas, 77014, United States

  • Kitasato University Hospital ( Site 5123)

    RECRUITING

    Sagamihara, Kanagawa, 252-0375, Japan

  • Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung-Klinik für Senologie/ Brustzentrum ( Site 4304)

    RECRUITING

    Essen, North Rhine-Westphalia, 45136, Germany

  • Kyoto University Hospital ( Site 5110)

    RECRUITING

    Kyoto, 606-8507, Japan

  • Kyungpook National University Chilgok Hospital ( Site 5205)

    RECRUITING

    Daegu, Taegu-Kwangyokshi, 41404, South Korea

  • Laboratorio de Patología Clínica del Hospital Universitario "Dr. José Eleuterio González" ( Site 2501)

    RECRUITING

    Monterrey, Nuevo León, 64460, Mexico

  • Lakeridge Health ( Site 0217)

    RECRUITING

    Oshawa, Ontario, L1G 2B9, Canada

  • Laura and Isaac Perlmutter Cancer Center ( Site 0003)

    RECRUITING

    New York, New York, 10016, United States

  • Liga Norte Riograndense Contra o Cancer ( Site 2310)

    RECRUITING

    Natal, Rio Grande do Norte, 59062-000, Brazil

  • LinYi Cancer Hospital ( Site 5021)

    RECRUITING

    Linyi, Shandong, 276000, China

  • Luisenkrankenhaus Düsseldorf ( Site 4305)

    COMPLETED

    Düsseldorf, North Rhine-Westphalia, 40235, Germany

  • ME RIVNE REGIONAL ANTITUMOR CENTER ( Site 4411)

    RECRUITING

    Rivne, Rivne Oblast, 33010, Ukraine

  • Mackay Memorial Hospital ( Site 5301)

    RECRUITING

    Taipei, 104, Taiwan

  • Manila Doctors Hospital ( Site 5701)

    RECRUITING

    Manila, National Capital Region, 1000, Philippines

  • Martini Ziekenhuis ( Site 4502)

    RECRUITING

    Groningen, 9728 NT, Netherlands

  • Mary Mediatrix Medical Center ( Site 5702)

    RECRUITING

    Lipa, Batangas, 4217, Philippines

  • Masarykuv onkologicky ustav ( Site 3500)

    RECRUITING

    Brno, South Moravian, 656 53, Czechia

  • Mazowiecki Szpital Onkologiczny ( Site 3807)

    RECRUITING

    Wieliszew, Masovian Voivodeship, 05-135, Poland

  • Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 3801)

    COMPLETED

    Siedlce, Masovian Voivodeship, 08-110, Poland

  • McGill University Health Centre ( Site 0204)

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Meander Medisch Centrum ( Site 4500)

    RECRUITING

    Amersfoort, Utrecht, 3813 TZ, Netherlands

  • MedStar Franklin Square Medical Center ( Site 0031)

    RECRUITING

    Baltimore, Maryland, 21237, United States

  • MedStar Good Samaritan Hospital ( Site 0079)

    RECRUITING

    Baltimore, Maryland, 21239, United States

  • MedStar Montgomery Medical Center ( Site 0078)

    RECRUITING

    Olney, Maryland, 20832, United States

  • MedStar Southern Maryland Hospital Center ( Site 0100)

    RECRUITING

    Clinton, Maryland, 20735, United States

  • Mie University Hospital ( Site 5109)

    RECRUITING

    Tsu, Mie-ken, 514-8507, Japan

  • Musgrove Park Hospital ( Site 4005)

    RECRUITING

    Taunton, Somerset, TA1 5DA, United Kingdom

  • Nagoya City University Hospital ( Site 5108)

    RECRUITING

    Nagoya, Aichi-ken, 467-8602, Japan

  • Naha Nishi Clinic ( Site 5125)

    RECRUITING

    Naha, Okinawa, 901-0154, Japan

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( Site 3803)

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • National Cancer Center ( Site 5202)

    RECRUITING

    Goyang-si, Kyonggi-do, 10408, South Korea

  • National Cancer Center Hospital East ( Site 5120)

    RECRUITING

    Kashiwa, Chiba, 277-8577, Japan

  • National Cancer Institute ( Site 5401)

    RECRUITING

    Putrajaya, Putrajaya, 62250, Malaysia

  • National Center for Global Health and Medicine ( Site 5105)

    RECRUITING

    Shinjuku, Tokyo, 162-8655, Japan

  • National Cheng Kung University Hospital ( Site 5304)

    RECRUITING

    Tainan, 70403, Taiwan

  • National Hospital Organization Kyushu Cancer Center ( Site 5119)

    RECRUITING

    Fukuoka, 811-1395, Japan

  • National Hospital Organization Shikoku Cancer Center ( Site 5122)

    RECRUITING

    Matsuyama, Ehime, 791-0280, Japan

  • National Taiwan University Hospital ( Site 5300)

    RECRUITING

    Taipei, 100225, Taiwan

  • New Mexico Oncology Hematology Consultants Ltd. ( Site 0019)

    RECRUITING

    Albuquerque, New Mexico, 87109, United States

  • North York General Hospital ( Site 0209)

    RECRUITING

    Toronto, Ontario, M2K 1E1, Canada

  • Nottingham University Hospital NHS Trust ( Site 4009)

    RECRUITING

    Nottingham, Nottinghamshire, NG51PB, United Kingdom

  • ONCOCENTRO APYS ( Site 2005)

    RECRUITING

    Viña del Mar, Valparaiso, 2520598, Chile

  • Odense Universitetshospital ( Site 3202)

    RECRUITING

    Odense, Region Syddanmark, 5000, Denmark

  • Okayama University Hospital ( Site 5118)

    RECRUITING

    Okayama, 700-8558, Japan

  • Oncare - Unidad Valle ( Site 2502)

    RECRUITING

    San Pedro Garza García, Nuevo León, 66220, Mexico

  • Oncologos Del Occidente ( Site 2208)

    RECRUITING

    Pereira, Risaralda Department, 660001, Colombia

  • Oncosalud ( Site 2600)

    RECRUITING

    Lima, 15036, Peru

  • Orlando Health Cancer Institute ( Site 0012)

    RECRUITING

    Orlando, Florida, 32806, United States

  • Országos Onkológiai Intézet-B-Belgyógyászati Onkológiai Osztály ( Site 3406)

    RECRUITING

    Budapest, 1122, Hungary

  • Osaka Prefectural Hospital Organization Osaka International Cancer Institute ( Site 5112)

    RECRUITING

    Osaka, 541-8567, Japan

  • Ospedale Policlinico San Martino ( Site 4606)

    RECRUITING

    Genova, 16132, Italy

  • Oulun yliopistollinen sairaala-Oncology and Hematology ( Site 3304)

    RECRUITING

    Oulu, North Ostrobothnia, 90220, Finland

  • Pantai Hospital Kuala Lumpur ( Site 5402)

    RECRUITING

    Kuala Lumpur, 59100, Malaysia

  • Parc de Salut Mar - Hospital del Mar ( Site 4106)

    RECRUITING

    Barcelona, 08003, Spain

  • Peninsula Health Frankston Hospital ( Site 5501)

    RECRUITING

    Frankston, Victoria, 3199, Australia

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 0073)

    RECRUITING

    Mineola, New York, 11501, United States

  • Policlincio Gemelli ( Site 4602)

    RECRUITING

    Roma, 00168, Italy

  • Pratia MCM Krakow ( Site 3812)

    RECRUITING

    Krakow, Lesser Poland Voivodeship, 30-727, Poland

  • Prince of Wales Hospital ( Site 6001)

    RECRUITING

    Hong Kong, Hong Kong

  • Princess Margaret Cancer Centre ( Site 0202)

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

  • Promotora Médica Las Américas S.A. ( Site 2206)

    RECRUITING

    Medellín, Antioquia, 050021, Colombia

  • Queen Elizabeth Hospital Birmingham ( Site 4017)

    RECRUITING

    Birmingham, B15 2TH, United Kingdom

  • Queen Mary Hospital ( Site 6000)

    RECRUITING

    Hong Kong, 000000, Hong Kong

  • Rabin Medical Center ( Site 3702)

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus ( Site 3700)

    RECRUITING

    Haifa, 3109601, Israel

  • Renown Regional Medical Center ( Site 0005)

    RECRUITING

    Reno, Nevada, 89502, United States

  • Rex Hematology Oncology Associates - Garner ( Site 0071)

    COMPLETED

    Garner, North Carolina, 27529, United States

  • Rigshospitalet University Hospital ( Site 3201)

    RECRUITING

    Copenhagen, Capital Region, 2100, Denmark

  • Royal Cornwall Hospital ( Site 4003)

    RECRUITING

    Truro, Cornwall, TR13LJ, United Kingdom

  • S.C. Radiotherapy Center Cluj S.R.L ( Site 4705)

    RECRUITING

    Comuna Floresti, Cluj, 407280, Romania

  • SCRI Oncology Partners ( Site 7004)

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Saitama Medical University International Medical Center ( Site 5116)

    RECRUITING

    Hidaka, Saitama, 350-1298, Japan

  • Sakarya Egitim Arastirma Hsatanesi ( Site 4809)

    RECRUITING

    Sakarya, 54290, Turkey (Türkiye)

  • Samsun Medical Park Hastanesi ( Site 4810)

    RECRUITING

    Samsun, 55200, Turkey (Türkiye)

  • Samsung Medical Center ( Site 5203)

    RECRUITING

    Seoul, 06351, South Korea

  • Sarawak General Hospital ( Site 5400)

    RECRUITING

    Kuching, Sarawak, 93586, Malaysia

  • Saskatoon Cancer Centre ( Site 0215)

    RECRUITING

    Saskatoon, Saskatchewan, S7N 4H4, Canada

  • Semmelweis Egyetem-Belgyógyászati és Onkológiai Klinika ( Site 3404)

    RECRUITING

    Budapest, 1082, Hungary

  • Seoul National University Bundang Hospital ( Site 5204)

    RECRUITING

    Seongnam, Kyonggi-do, 13620, South Korea

  • Seoul National University Hospital ( Site 5200)

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System ( Site 5201)

    RECRUITING

    Seoul, 03722, South Korea

  • Shaare Zedek Medical Center ( Site 3704)

    RECRUITING

    Jerusalem, 9103102, Israel

  • Shanxi Cancer Hospital ( Site 5043)

    RECRUITING

    Taiyuan, Shanxi, 030000, China

  • Sheba Medical Center ( Site 3701)

    RECRUITING

    Ramat Gan, 5265601, Israel

  • Showa Medical University Hospital ( Site 5103)

    RECRUITING

    Shinagawa, Tokyo, 142-8666, Japan

  • Sichuan Cancer Hospital. ( Site 5018)

    RECRUITING

    Chengdu, Sichuan, 610041, China

  • Social medical corporation Hakuaikai Sagara Hospital ( Site 5114)

    RECRUITING

    Kagoshima, 892-0833, Japan

  • Songklanagarind hospital ( Site 5801)

    RECRUITING

    Hat Yai, Changwat Songkhla, 90110, Thailand

  • Sourasky Medical Center ( Site 3703)

    RECRUITING

    Tel Aviv, 6423906, Israel

  • Spitalul Clinic Filantropia ( Site 4703)

    RECRUITING

    Bucharest, 011171, Romania

  • Spitalul Municipal Schuller Ploiești ( Site 4707)

    RECRUITING

    Ploieşti, Prahova, 100337, Romania

  • St Bartholomew's Hospital ( Site 4001)

    RECRUITING

    London, London, City of, EC1A7BE, United Kingdom

  • St. James s University Hospital ( Site 4004)

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • St. Luke's Cancer Institute: Boise ( Site 0037)

    RECRUITING

    Boise, Idaho, 83712, United States

  • St. Marianna University Hospital ( Site 5124)

    RECRUITING

    Kawasaki, Kanagawa, 216-8511, Japan

  • St. Marys Hospital Center ( Site 0201)

    RECRUITING

    Montreal, Quebec, H3T 1M5, Canada

  • Sun Yat-Sen University Cancer Center ( Site 5014)

    RECRUITING

    Guangzhou, Guangdong, 510060, China

  • Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterapias Klinika ( Site 3407)

    RECRUITING

    Szeged, Csongrád megye, 6720, Hungary

  • Szpital Wojewodzki im.M.Kopernika. ( Site 3800)

    RECRUITING

    Koszalin, West Pomeranian Voivodeship, 75-581, Poland

  • Szpitale Pomorskie Sp. z o. o. ( Site 3805)

    RECRUITING

    Gdynia, Pomeranian Voivodeship, 81-519, Poland

  • TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi ( Site 4802)

    RECRUITING

    Istanbul, 34722, Turkey (Türkiye)

  • THE MEDICAL CITY ILOILO ( Site 5704)

    RECRUITING

    Iloilo City, 5000, Philippines

  • Taichung Veterans General Hospital ( Site 5303)

    RECRUITING

    Taichung, 407, Taiwan

  • Taizhou Hospital of Zhejiang Province ( Site 5029)

    RECRUITING

    Linhai, Zhejiang, 317000, China

  • Tampereen yliopistollinen sairaala-Oncology ( Site 3302)

    RECRUITING

    Tampere, Pirkanmaa, 33520, Finland

  • Tennessee Oncology ( Site 0018)

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Texas Oncology - DFW ( Site 8007)

    RECRUITING

    Dallas, Texas, 75231, United States

  • Texas Oncology - San Antonio ( Site 8001)

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Texas Oncology - West Texas ( Site 8004)

    RECRUITING

    El Paso, Texas, 79902, United States

  • The First Affiliated Hospital Zhejiang University School of Medicine ( Site 5026)

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

  • The First Affiliated Hospital of Chongqing Medical University ( Site 5039)

    RECRUITING

    Chongqing, Chongqing Municipality, 400016, China

  • The First Affiliated Hospital of Xi an Jiaotong University ( Site 5005)

    RECRUITING

    Xi'an, Shaanxi, 710061, China

  • The First Affiliated hospital of Xiamen University ( Site 5035)

    RECRUITING

    Xiamen, Fujian, 361003, China

  • The First Afflilated Hospital of Bengbu Medical College ( Site 5022)

    RECRUITING

    Bengbu, Anhui, 233004, China

  • The First Hospital of Jilin University ( Site 5003)

    RECRUITING

    Changchun, Jilin, 130021, China

  • The Second Affiliated hospital of Zhejiang University school of medicine ( Site 5024)

    RECRUITING

    Hangzhou, Zhejiang, 310052, China

  • The Second People's Hospital of Neijiang ( Site 5016)

    RECRUITING

    Neijiang, Sichuan, 641099, China

  • The University of Osaka Hospital ( Site 5111)

    RECRUITING

    Suita, Osaka, 565-0871, Japan

  • Tokai University Hospital ( Site 5107)

    RECRUITING

    Isehara, Kanagawa, 259-1193, Japan

  • Tokyo Medical University Hospital ( Site 5121)

    ACTIVE_NOT_RECRUITING

    Shinjuku, Tokyo, 160-0023, Japan

  • Tongji Hospital Tongji Medical Science & Technology ( Site 5007)

    RECRUITING

    Wuhan, Hubei, 430030, China

  • Toranomon Hospital ( Site 5126)

    RECRUITING

    Minato, Tokyo, 105-8470, Japan

  • UCLA Department of Medicine - Hematology & Oncology ( Site 0047)

    RECRUITING

    Los Angeles, California, 90095, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center ( Site 0016)

    RECRUITING

    San Francisco, California, 94158, United States

  • USA Mitchell Cancer Institute ( Site 0090)

    RECRUITING

    Mobile, Alabama, 36604, United States

  • UZ Gent ( Site 3101)

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • Unidad de Mastologia Avanzada de Chihuahua S.A de C.V ( Site 2510)

    RECRUITING

    Chihuahua City, 31123, Mexico

  • Universitaetsklinikum Leipzig ( Site 4307)

    RECRUITING

    Leipzig, Saxony, 04103, Germany

  • Universitatsklinikum Erlangen ( Site 4302)

    RECRUITING

    Erlangen, Bavaria, 91054, Germany

  • University Cancer & Blood Center, LLC ( Site 0023)

    RECRUITING

    Athens, Georgia, 30607, United States

  • University College London Hospital ( Site 4007)

    RECRUITING

    London, London, City of, NW1 2PG, United Kingdom

  • University General Hospital of Heraklion-Internal Medicine-Oncology ( Site 3903)

    RECRUITING

    Heraklion, Irakleio, 715 00, Greece

  • University Malaya Medical Centre ( Site 5403)

    RECRUITING

    Kuala Lumpur, 59100, Malaysia

  • University of Illinois Cancer Center ( Site 0044)

    RECRUITING

    Chicago, Illinois, 60612, United States

  • University of Utah, Huntsman Cancer Institute ( Site 0056)

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Velindre Cancer Centre Hospital ( Site 4008)

    RECRUITING

    Cardiff, CF142TL, United Kingdom

  • Virginia Oncology Associates (VOA) ( Site 8002)

    RECRUITING

    Norfolk, Virginia, 23502, United States

  • Vseobecna fakultni nemocnice v Praze ( Site 3501)

    RECRUITING

    Prague, Praha 2, 128 00, Czechia

  • Washington Hospital Center ( Site 0098)

    RECRUITING

    Washington D.C., District of Columbia, 20010-2975, United States

  • Wielkopolskie Centrum Onkologii-Oddział Onkologii Klinicznej i Immunoonkologii z Pododdziałem Dzien ( Site 3811)

    RECRUITING

    Poznan, Greater Poland Voivodeship, 61-866, Poland

  • Xiangyang Central Hospital ( Site 5017)

    RECRUITING

    Xiangyang, Hubei, 441021, China

  • Xuzhou Central Hospital ( Site 5036)

    RECRUITING

    Xuzhou, Jiangsu, 221009, China

  • Yale New Haven Hospital ( Site 0001)

    COMPLETED

    New Haven, Connecticut, 06520, United States

  • ZAS Sint Augustinus ( Site 3102)

    RECRUITING

    Antwerp, Flanders, 2610, Belgium

  • Zhejiang Cancer Hospital ( Site 5012)

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

  • Ziekenhuis Oost Limburg ( Site 3105)

    RECRUITING

    Genk, Limburg, 3600, Belgium

  • Ziekenhuis Rijnstate ( Site 4501)

    RECRUITING

    Arnhem, Gelderland, 6815 AD, Netherlands

  • Zuyderland Medical Centre ( Site 4507)

    RECRUITING

    Sittard Geleen, Limburg, 6162BP, Netherlands

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