New drug combo trial aims to fight advanced cancers

NCT ID NCT04895709

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests a new drug called BMS-986340, alone or with other cancer treatments, in people with advanced solid tumors like lung, colon, or breast cancer. The goal is to find safe doses and check for side effects. About 1,100 adults with tumors that have worsened after standard therapy will take part.

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Conditions

The condition(s) this trial relates to.

cervical cancer colorectal cancer colorectal carcinoma gastroesophageal junction adenocarcinoma head and neck squamous cell carcinoma melanoma non-small cell lung carcinoma ovarian cancer ovarian neoplasm pancreatic adenocarcinoma renal cell adenocarcinoma renal cell carcinoma Squamous Cell Carcinoma of Head and Neck transitional cell carcinoma triple-negative breast carcinoma urothelial carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, RENAL CELL CERVICAL CANCER GASTRIC / GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA MELANOMA MICROSATELLITE STABLE COLORECTAL CANCER NON-SMALL CELL LUNG CANCER OVARIAN NEOPLASMS PANCREATIC ADENOCARCINOMA SQUAMOUS CELL CARCINOMA OF HEAD AND NECK TRIPLE NEGATIVE BREAST NEOPLASMS UROTHELIAL CARCINOMA

Contacts and locations

Locations

Blacktown Hospital
RECRUITING

Blacktown, New South Wales, 2148, Australia
Cabrini Hospital - Malvern
RECRUITING

Malvern, Victoria, 3144, Australia
Centre Hospitalier de luniversite de Montreal
RECRUITING

Montreal, Quebec, H2X 0A9, Canada
Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid-CIOCC
RECRUITING

Madrid, 28050, Spain
Clinica Universidad de Navarra-oNCOLOGY
RECRUITING

Pamplona, 31008, Spain
Community Cancer Institute
RECRUITING

Clovis, California, 93611, United States
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6X 1E8, Canada
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1
RECRUITING

Milan, 20133, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
RECRUITING

Roma, 00168, Italy
Hamilton Health Sciences-Juravinski Cancer Centre
RECRUITING

Hamilton, Ontario, L8V5C2, Canada
Hoag Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 92663, United States
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona [Barcelona], 08035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Madrid, Comunidad de, 28041, Spain
Hospital Universitario Fundación Jiménez Díaz-START Madrid-FJD
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, Andalusia, 29010, Spain
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Humanitas
RECRUITING

Rozzano, Milano, 20089, Italy
Institut Catalan d Oncologia (ICO) - Badalona
RECRUITING

Badalona, Barcelona [Barcelona], 08916, Spain
Istituto Nazionale Tumori IRCCS Fondazione Pascale
RECRUITING

Naples, 80131, Italy
Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia
RECRUITING

Candiolo, Torino, 10060, Italy
John Theurer Cancer Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Liverpool Hospital
RECRUITING

Liverpool, New South Wales, 2170, Australia
Local Institution - 0002
COMPLETED

New York, New York, 10065, United States
Local Institution - 0006
COMPLETED

New York, New York, 10032, United States
Local Institution - 0009
COMPLETED

Toronto, Ontario, M5G 2M9, Canada
Local Institution - 0016
COMPLETED

Ottawa, K1H 8L6, Canada
Local Institution - 0030
COMPLETED

Vancouver, British Columbia, V5Z 4E6, Canada
Local Institution - 0035
WITHDRAWN

Ramat Gan, Central District, 5265601, Israel
Local Institution - 0044
COMPLETED

Ulm, Baden-Wurttemberg, 89081, Germany
Local Institution - 0063
NOT_YET_RECRUITING

Nashville, Tennessee, 37067, United States
National Cancer Center Hospital East
RECRUITING

Kashiwa, Chiba, 277-8577, Japan
One Clinical Research
RECRUITING

Nedlands, Western Australia, 6009, Australia
Princess Alexandra Hospital
RECRUITING

Brisbane, Queensland, 4102, Australia
Providence Cancer Center Oncology and Hematology Care- Eastside
RECRUITING

Portland, Oregon, 97213, United States
Rabin Medical Center
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Rambam Health Care Campus
RECRUITING

Haifa, Northern District, 3109601, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5265601, Israel
Sourasky Medical Center
RECRUITING

Tel Aviv, Tell Abīb, 6423906, Israel
St Vincent's Hospital
RECRUITING

Melbourne, Victoria, 3065, Australia
USC/Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States
Universitaetsklinikum Carl Gustav Carus Dresden-University Cancer Center Early Clinical Trial Unit
RECRUITING

Dresden, 01307, Germany
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Wuerzburg
RECRUITING

Würzburg, 97078, Germany
Universitatsklinikum Frankfurt
RECRUITING

Frankfurt, 60590, Germany
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
ospedale le scotte-U.O.C. Immunoterapia Oncologica
RECRUITING

Siena, 53100, Italy

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