SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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New drug combo aims to extend life in head and neck cancer
Disease control Recruiting nowThis study tests whether adding the drug amivantamab to standard chemotherapy and immunotherapy can help people with advanced head and neck cancer live longer. About 500 adults who have not had prior treatment for their recurrent or metastatic cancer will take part. The goal is t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 16, 2026 22:34 UTC
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New antibody drug takes aim at Hard-to-Treat cancers
Disease control Recruiting nowThis trial tests a new drug, UCB4594, designed to help the immune system attack cancer cells by targeting a protein called HLA-G found on many tumors. It is for people with advanced solid cancers that have not responded to standard treatments. The study aims to find the safest do…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Cancer Research UK • Aim: Disease control
Last updated May 16, 2026 22:34 UTC
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New drug combo aims to shrink head and neck tumors
Disease control Recruiting nowThis study tests a drug called amivantamab, alone or with other cancer medicines, in people with head and neck cancer that has spread or come back. The goal is to see if these treatments can shrink tumors and are safe. About 287 adults will take part.
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 16, 2026 22:30 UTC
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New injection plus Chemo-Radiation targets tough head and neck cancers
Disease control Recruiting nowThis early-stage study tests whether a new drug called JNJ-90301900, injected directly into tumors, is safe and works well when combined with standard chemotherapy and radiation. About 30 adults with advanced head and neck cancer that has not spread will take part. The main goal …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated May 16, 2026 22:30 UTC
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New hope for advanced cancer: experimental drug DM005 enters first human trials
Disease control Recruiting nowThis early-phase trial tests an experimental drug, DM005, in about 136 people with advanced solid tumors (like lung, head and neck, or other cancers) that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see how wel…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd. • Aim: Disease control
Last updated May 16, 2026 22:29 UTC
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New drug duo aims to shrink tough head and neck tumors
Disease control Recruiting nowThis study tests a new combination of two drugs (SI-B001 and SI-B003) with or without chemotherapy in people with advanced head and neck cancer that has spread or cannot be removed. The goal is to find the best dose and see if the treatment can shrink tumors. About 130 adults age…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 16, 2026 22:26 UTC
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New hope for advanced cancers? early trial launches
Disease control Recruiting nowThis study tests a new drug, BMS-986340, alone or with other cancer treatments in people with advanced solid tumors that have not responded to standard therapy. The main goal is to find safe doses and check for side effects. About 949 adults with various cancers like lung, breast…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Could less chemo be just as effective? new trial for head and neck cancer
Disease control Recruiting nowThis study is for people with a type of head and neck cancer that has come back or spread. It tests whether giving only 4 cycles of chemotherapy (instead of the usual 6) together with the immunotherapy drug pembrolizumab can still control the cancer while causing fewer side effec…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Institut Claudius Regaud • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Could a yeast vaccine keep head and neck cancer at bay?
Disease control Recruiting nowThis study tests a vaccine made from Candida (a common yeast) to see if it can reduce the risk of head and neck cancer returning after standard treatment. About 80 adults who have finished curative therapy and are currently cancer-free will receive either the vaccine or a placebo…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Arkansas • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New drug combo aims to shrink Hard-to-Treat head and neck tumors
Disease control Recruiting nowThis study tests whether combining two drugs, sacituzumab govitecan and cetuximab, can shrink tumors in people with advanced head and neck cancer that has returned or spread after initial treatment. About 40 adults whose cancer worsened after first-line therapy will receive the c…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Could a drug combo boost immune attack on HPV head and neck tumors?
Disease control Recruiting nowThis study tests whether combining a chemotherapy (5-azacytidine) with an immunotherapy (nivolumab) works better than either drug alone for HPV-related head and neck cancer. About 50 people with resectable tumors will receive the drugs before surgery. The goal is to see if the co…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Barbara Burtness • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New dosing strategy for chemo drug aims to improve outcomes in Tough-to-Treat head and neck cancer
Disease control Recruiting nowThis study tests two different schedules of the chemotherapy drug 5-FU in people with advanced head and neck cancer that has not responded to prior treatments. About 46 participants will receive the drug either over two days every two weeks or over four days every three weeks. Th…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New drug duo aims to supercharge immune attack on head and neck tumors before surgery
Disease control Recruiting nowThis early-phase trial tests whether adding an experimental skin injection (CADI-05) to standard immunotherapy (pembrolizumab) can help the immune system better fight advanced head and neck cancer before surgery. About 22 adults with resectable, locally advanced disease will rece…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Fox Chase Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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New hope for advanced cancers: first human trial of TH9619 begins
Disease control Recruiting nowThis early-phase study tests a new drug called TH9619 in people with advanced solid tumors, including colorectal, head and neck, lung, and stomach cancers. The main goal is to find a safe dose and check for side effects. About 43 adults who have already tried at least one standar…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: One-carbon Therapeutics AB • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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New drug combo trial aims to tame tough cancers
Disease control Recruiting nowThis early-stage trial tests a drug called sigvotatug vedotin, alone or with other medicines, in people with advanced solid tumors like lung, head and neck, or breast cancer. The main goal is to check safety and find the right dose. About 1,000 participants will join this study t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New drug MGC026 enters human testing for advanced cancers
Disease control Recruiting nowThis study is testing an experimental drug called MGC026 in about 250 adults with advanced solid tumors that have not responded to other treatments. The main goals are to check the drug's safety and find the right dose. Participants receive the drug by IV and are closely monitore…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: MacroGenics • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New drug combo offers hope for tough head and neck cancers
Disease control Recruiting nowThis study is for people with head and neck cancer that has come back or spread after at least one prior treatment. It tests two antibodies (iparomlimab and tuvonralimab) given together, either alone or with chemotherapy. The goal is to see if this combination can shrink tumors o…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: The Second Affiliated Hospital of Hainan Medical University • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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Can better nutrition help cancer patients finish Life-Saving treatment?
Disease control Recruiting nowThis study looks at whether early nutritional and supportive care can help people with head and neck cancer complete their full course of radiation and chemotherapy. Many patients struggle with weight loss and side effects, which can prevent them from finishing treatment. The stu…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated May 07, 2026 18:40 UTC
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New study aims to unlock secrets of radiation therapy in head and neck cancer
Knowledge-focused Recruiting nowThis study is for people newly diagnosed with head and neck squamous cell carcinoma who are scheduled for curative treatment. Researchers want to see how radiation therapy changes MRI scans and immune system markers in the tumor. By taking biopsies and scans before and during tre…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 16, 2026 22:32 UTC
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New study peers inside head and neck tumors to unlock clues for better treatment
Knowledge-focused Recruiting nowThis study looks at how head and neck tumors change during treatment by using special MRI scans and tissue samples. About 60 adults with newly diagnosed head and neck cancer will take part. The goal is to find markers that could help doctors personalize care in the future.
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Tiny implant could reveal which cancer drug works for you
Knowledge-focused Recruiting nowThis study is testing a small implantable device that delivers tiny amounts of different drugs directly into head and neck tumors. The goal is to see which drugs kill cancer cells best in each person, without giving the full treatment yet. About 30 adults with certain head and ne…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC
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Blood test may spot returning head and neck cancer early
Knowledge-focused Recruiting nowThis study looks at whether a blood test that finds tiny bits of tumor DNA (called ctDNA) can tell if head and neck cancer has returned after successful treatment. Researchers will follow 250 adults who have finished curative surgery or radiation. The goal is to see if a positive…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 05, 2026 11:53 UTC