SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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New drug combo trial aims to fight advanced cancers
Disease control Recruiting nowThis study tests a new drug called BMS-986340, alone or with other cancer treatments, in people with advanced solid tumors like lung, colon, or breast cancer. The goal is to find safe doses and check for side effects. About 1,100 adults with tumors that have worsened after standa…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jul 01, 2026 22:00 UTC
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Could a Chemo-Immuno combo boost cancer fight before surgery?
Disease control Recruiting nowThis phase 2 trial tests whether combining the chemotherapy 5-azacytidine with the immunotherapy nivolumab can make HPV-related head and neck cancer more responsive to treatment. About 50 people with resectable tumors will receive one or both drugs before surgery. The goal is to …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Barbara Burtness • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New injection plus chemo-radiation targets tough head and neck tumors
Disease control Recruiting nowThis early-stage study is testing whether a new drug, JNJ-90301900, is safe and works when injected directly into tumors along with standard chemotherapy and radiation. It involves 30 adults with advanced head and neck cancer. The main goal is to check for side effects and see ho…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New drug cocktail aims to outsmart head and neck cancer
Disease control Recruiting nowThis Phase 3 trial is testing whether adding the targeted drug amivantamab to standard immunotherapy and chemotherapy can help people with advanced head and neck cancer live longer. About 500 participants who have not had prior treatment for their recurrent or metastatic cancer w…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New drug cocktail aims to fight head and neck cancer
Disease control Recruiting nowThis study tests a drug called amivantamab, either alone or combined with other cancer drugs (pembrolizumab, paclitaxel, carboplatin), in people with head and neck cancer that has spread or come back. The goal is to see if these treatments are safe and can shrink tumors. About 28…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New cancer drug sigvotatug vedotin enters human trials
Disease control Recruiting nowThis early-stage trial is testing a new drug called sigvotatug vedotin, alone or with other cancer medicines, in people with advanced solid tumors like lung, head and neck, and breast cancers. The study aims to find a safe dose and check for side effects. About 1,000 participants…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New antibody drug aims to unleash immune system on Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase trial tests a new drug, UCB4594, in people with advanced solid tumors that haven't responded to standard treatments. The drug is a monoclonal antibody that targets a protein called HLA-G on cancer cells, potentially helping the immune system attack them. The stud…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Cancer Research UK • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Can a shorter chemo schedule work as well for head and neck cancer?
Disease control Recruiting nowThis study compares two ways of giving the chemotherapy drug 5-FU to people with head and neck cancer that has spread or come back after prior treatments. One group gets the drug over two days every two weeks, the other over four days every three weeks. The goal is to see which s…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New drug combo offers hope for tough head and neck cancers
Disease control Recruiting nowThis study tests two antibodies (iparomlimab and tuvonralimab) given together, with or without chemotherapy, for people with advanced head and neck cancer that has come back or spread after at least one prior treatment. The goal is to see if the combination can shrink tumors and …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: The Second Affiliated Hospital of Hainan Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New drug duo aims to supercharge immune attack on head and neck tumors before surgery
Disease control Recruiting nowThis early-phase study tests whether adding an experimental drug (CADI-05) to standard immunotherapy (pembrolizumab) can help the immune system better fight advanced head and neck cancer before surgery. About 22 adults with resectable, locally advanced disease will receive both t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Fox Chase Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Could a yeast vaccine stop Cancer's return?
Disease control Recruiting nowThis study tests a vaccine made from candida (a type of yeast) to see if it can reduce the risk of head and neck cancer coming back. About 100 adults who have finished cancer treatment and are currently cancer-free will receive either the vaccine or a placebo over two years. The …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Arkansas • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New drug duo offers hope for hard-to-treat head and neck cancer
Disease control Recruiting nowThis study tests whether combining two drugs, sacituzumab govitecan and cetuximab, can shrink or control advanced head and neck cancer that has grown after initial therapy. About 40 adults whose cancer has spread or returned will receive the combination. The goal is to see how ma…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Could less chemo be enough? new trial tests shorter treatment for head and neck cancer
Disease control Recruiting nowThis phase 2 trial is testing whether giving only 4 cycles of chemotherapy alongside the immunotherapy drug pembrolizumab can effectively treat PD-L1-positive head and neck cancer that has spread or come back. Standard treatment usually involves 6 cycles of chemo. The study will …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Institut Claudius Regaud • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New drug MGC026 takes on advanced cancers in first human trial
Disease control Recruiting nowThis early-phase trial tests MGC026, a biologic drug given by IV, in 250 adults with advanced solid tumors that have not responded to standard treatments. The study has two parts: first, finding a safe dose, then expanding to see if the drug shrinks tumors. Participants receive u…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: MacroGenics • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New hope for advanced cancers? first human trial of TH9619 begins
Disease control Recruiting nowThis early-phase trial is testing an experimental drug called TH9619 in about 43 adults with advanced solid tumors, including colorectal, head and neck, lung, and gastric cancers. The main goal is to check the drug's safety and find the right dose. Participants must have already …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: One-carbon Therapeutics AB • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Experimental drug DM005 enters first human tests for advanced cancers
Disease control Recruiting nowThis early-stage trial is testing an experimental drug called DM005 in 136 people with advanced solid tumors, including lung, head and neck, and other cancers that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and se…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New study aims to help head and neck cancer patients complete Life-Saving treatment
Disease control Recruiting nowThis study tests whether early nutritional and medical support helps people with head and neck cancer complete their full course of radiation and chemotherapy. Many patients struggle to finish treatment due to weight loss and side effects. The study will enroll 138 adults and mea…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New drug duo aims to shrink tough head and neck tumors
Disease control Recruiting nowThis study tests a new combination of two drugs (SI-B001 and SI-B003) with or without chemotherapy in people with advanced head and neck cancer that has spread or cannot be removed. The goal is to find the safest dose and see if the treatment can shrink tumors. About 130 adults a…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New PET tracer aims to illuminate hidden HER2 tumors
Diagnosis Recruiting nowThis early-phase study tests a radioactive tracer called [68Ga]Ga-ABY-025 for PET scans in 30 adults with advanced HER2-positive cancers (breast, gastric, head/neck, esophageal). Participants receive the tracer and a PET/CT scan before or during standard HER2-targeted therapy. Th…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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New study aims to decode head and neck tumors using MRI and tissue tests
Knowledge-focused Recruiting nowThis study looks at how head and neck tumors change during treatment using special MRI scans and tissue samples. Sixty adults with newly diagnosed head and neck cancer will take a pill called pimonidazole, which highlights low-oxygen areas in tumors, and undergo repeat imaging. T…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New study aims to unlock Radiation's hidden effects on head and neck cancer
Knowledge-focused Recruiting nowThis study is for people newly diagnosed with head and neck squamous cell carcinoma who are scheduled for curative surgery or radiation therapy. Researchers want to see how radiation changes MRI scans and immune-related markers in tumors. About 40 participants will be randomly as…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Microchip implant could personalize cancer drug selection
Knowledge-focused Recruiting nowThis early-phase study is testing a small implantable device that delivers tiny amounts of different drugs directly into head and neck tumors. The goal is to see which drugs are most effective for each person before they undergo full treatment. The study involves 30 adults with c…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Blood test may spot head and neck Cancer's return
Knowledge-focused Recruiting nowThis study looks at whether a blood test that finds tumor DNA can predict if head and neck cancer comes back after treatment. About 250 adults who have finished curative treatment will give blood samples over time. The goal is to see if a positive test result matches cancer relap…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC