SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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Experimental drug enters human testing for Tough-to-Treat cancers
Disease control Recruiting nowThis is the first human trial of an experimental cancer drug called DM005. The study aims to find a safe and effective dose for patients with advanced solid tumors like lung and head/neck cancer that have stopped responding to standard treatments. Researchers will give the drug t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New weapon against advanced cancer enters human testing
Disease control Recruiting nowThis is the first study in people testing a new cancer drug called MGC026. It aims to find a safe dose and see if the drug can help shrink tumors in adults with advanced solid tumors that have not responded to other treatments. The study will also check how the drug moves through…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: MacroGenics • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug combo trial offers hope for tough head and neck cancers
Disease control Recruiting nowThis study is testing a drug called amivantamab, both by itself and combined with other cancer drugs, for people with advanced head and neck cancer. The main goals are to find safe doses and see if these treatments can shrink tumors or help people live longer. It will include abo…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New support strategy aims to help more cancer patients complete tough treatment
Disease control Recruiting nowThis study is testing whether starting nutrition and pain management early can help more people with head and neck cancer finish their full course of chemotherapy and radiation. Researchers want to see if this extra support helps patients lose less weight, complete more treatment…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug duo targets tough head & neck cancers
Disease control Recruiting nowThis study is testing two new drugs, SI-B001 and SI-B003, for people with advanced head and neck cancer that has spread or cannot be removed by surgery. The first part finds the safest and most effective dose. The second part checks how well the drug combination works to shrink t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Cancer trial aims to cut chemotherapy by a third
Disease control Recruiting nowThis study is testing if a shorter course of chemotherapy works as well as the standard longer course when combined with an immunotherapy drug for advanced head and neck cancer. It will involve 86 patients whose cancer has returned or spread and who have not yet received treatmen…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Institut Claudius Regaud • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for Tough-to-Treat head and neck cancer in major trial
Disease control Recruiting nowThis study is testing if adding a new drug, amivantamab, to standard chemotherapy and immunotherapy works better for advanced head and neck cancer that has returned or spread. It will involve about 500 adults who have not yet received treatment for their advanced cancer. The main…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New Two-Drug attack on tough head & neck cancers
Disease control Recruiting nowThis study is testing whether a combination of two drugs, sacituzumab govitecan and cetuximab, can help control advanced head and neck cancer that has come back or spread after initial treatment. It will involve about 40 adults whose cancer has progressed despite standard therapy…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Direct tumor injection trial offers new hope for tough head & neck cancers
Disease control Recruiting nowThis early-stage study is testing whether injecting an experimental drug called JNJ-90301900 directly into tumors is safe and helps shrink cancer when given alongside standard chemotherapy and radiation. It will enroll about 30 people with locally advanced head and neck squamous …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug duo aims to supercharge immune system against HPV cancer before surgery
Disease control Recruiting nowThis study is testing if giving two drugs—one chemotherapy and one immunotherapy—before surgery can better prepare the immune system to fight HPV-linked head and neck cancer. It will compare using the drugs alone or together in about 50 people with early-stage, operable cancer. T…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Barbara Burtness • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Groundbreaking first human trial launches for new cancer fighter
Disease control Recruiting nowThis is the first-ever study in humans of a new experimental drug called TH9619 for people with advanced solid tumors. The trial aims to find a safe and effective dose while checking how the body processes the drug and whether it shows signs of fighting cancer. It's open to adult…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: One-carbon Therapeutics AB • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New hope for tough cancers: first human trial of experimental drug begins
Disease control Recruiting nowThis study is testing a new drug called BMS-986340 to see if it is safe and can help control advanced cancers. It will be given alone or combined with two other cancer drugs to about 950 people whose cancers have grown despite standard treatments. The main goal is to find the rig…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New cancer drug trial tests experimental treatment for multiple tumor types
Disease control Recruiting nowThis early-stage trial is testing an experimental drug called sigvotatug vedotin for people with advanced solid tumors that have spread or cannot be removed by surgery. The study will first determine safe doses, then test the drug alone and in combination with other cancer medica…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Blood test could warn of Cancer's return before scans can see it
Knowledge-focused Recruiting nowThis study is testing a blood test to see if it can find tiny leftover cancer cells after treatment for head and neck cancer. Researchers will follow 250 patients for two years to see if a positive blood test predicts if the cancer will return. The study is observational, meaning…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists map Cancer's hidden changes during treatment
Knowledge-focused Recruiting nowThis study aims to better understand head and neck cancer by comparing MRI scan images with actual tumor tissue samples taken during treatment. Researchers will follow 60 patients receiving either radiation or surgery, collecting multiple scans and biopsies to see how the cancer …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Needle-Tip device tests 20 cancer drugs inside tumors
Knowledge-focused Recruiting nowThis study is testing a tiny, needle-tip-sized device that can be implanted into a head or neck cancer tumor. The device releases tiny amounts of up to 20 different drugs into the tumor for a few days before it is removed during the patient's scheduled surgery. The goal is to saf…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:55 UTC
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Scientists probe if delaying radiation changes the Tumor's environment
Knowledge-focused Recruiting nowThis study aims to understand how the timing of radiation therapy affects head and neck cancer tumors. Researchers will enroll 40 patients and randomly assign them to receive standard radiation or a schedule where some areas are treated later. The main goal is to see if delaying …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC