SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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Experimental drug aims to attack cancer before surgery
Disease control TerminatedThis study aimed to test if a drug called TTI-101 could reduce the size of head and neck cancers before patients had standard surgery. The trial planned to give the drug for a short period before the planned operation to see if it made the tumors easier to remove. However, the st…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Nanoparticle 'Booster' trial aims to supercharge cancer treatment
Disease control OngoingThis early-stage trial is testing whether injecting a nanoparticle called NBTXR3 directly into a tumor, then activating it with radiation, can make immunotherapy work better for people with advanced cancers. The study will enroll about 145 patients with various cancers that have …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Nanobiotix • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Scientists test re-engineered immune cells to fight tough head and neck cancers
Disease control OngoingThis early-stage study is testing the safety of a new combination treatment for people with advanced head and neck cancer that has come back or spread. Doctors take a patient's own immune cells from a tumor, grow and select them in a lab, and then infuse them back along with an i…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 27, 2026 12:43 UTC
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New cancer drug enters first human trials for advanced tumors
Disease control OngoingThis is the first human study testing a new cancer drug called AB248, either alone or combined with an existing immunotherapy (pembrolizumab). The trial aims to find safe doses and see if the treatment shows early signs of helping adults with advanced solid tumors that have sprea…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Asher Biotherapeutics, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug duo aims to boost fight against tough head and neck cancers
Disease control OngoingThis study is testing whether adding two drugs, pembrolizumab and olaparib, before and after standard chemoradiation can better control a difficult-to-treat form of head and neck cancer. It will involve about 45 adults with locally advanced cancer who have not had prior treatment…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New hope drug enters first human tests for dozens of tough cancers
Disease control OngoingThis is an early-stage study to find a safe dose of a new drug called KFA115, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced cancers that have stopped responding to standard treatments. The main goal is to check for side effects and determ…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Personalized vaccine trial aims to train immune system to fight cancer recurrence
Disease control OngoingThis trial is testing a personalized immunotherapy called TG4050 in patients with advanced head and neck cancer who have completed initial treatment. The goal is to see if this vaccine, designed to target each patient's specific cancer mutations, is safe and can help prevent the …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Transgene • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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New microscope aims to help surgeons spot cancer cells in Real-Time
Diagnosis OngoingThis study is testing a special microscope to help surgeons see if they have removed all the cancer cells during an operation. It is being used for skin cancers and head/neck cancers. The goal is to see if this microscope is as accurate as the current standard lab test, which tak…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Institut de Cancérologie de Lorraine • Aim: Diagnosis
Last updated Mar 20, 2026 14:48 UTC
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Scientists hunt for cancer clues in saliva
Knowledge-focused OngoingThis study aims to find tiny molecules called miRNAs in saliva, blood, and tissue samples that could help detect or monitor head and neck cancer. Researchers are enrolling 225 people, including those with cancer and those without, to compare these molecular markers. The goal is t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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Scientists test drug duo in brief window before cancer surgery
Knowledge-focused OngoingThis is a small, early-stage study to learn how head and neck cancer tumors respond to a short course of two drugs, imatinib and cetuximab, given in the time between diagnosis and the start of standard treatment like surgery or radiation. Researchers will take small tumor samples…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC