SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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New drug combo shows promise for tough cancers
Disease control OngoingThis early-stage study tests a new drug called KFA115, alone or with pembrolizumab, in people with advanced cancers like lung, skin, kidney, and others. The main goal is to find the safest dose and understand side effects. About 126 participants will be enrolled to see if the tre…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 16, 2026 23:49 UTC
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New combo therapy aims to boost immune attack on hard-to-treat cancers
Disease control OngoingThis early-phase study tests a new drug called NBTXR3, which is injected into tumors and activated by radiation. It is combined with an immunotherapy (anti-PD-1) to see if it can help the immune system fight advanced cancers better. About 145 adults with various advanced solid tu…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Nanobiotix • Aim: Disease control
Last updated May 16, 2026 23:48 UTC
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Custom-Made vaccine aims to stop head and neck cancer return
Disease control OngoingThis study tests a personalized immunotherapy called TG4050 for patients with newly diagnosed, advanced head and neck cancer. After standard treatment (surgery and possibly other therapies), participants receive a vaccine tailored to their tumor's unique mutations. The goal is to…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Transgene • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a new drug called AB248, alone or with another drug (pembrolizumab), in adults with advanced solid tumors like lung cancer, melanoma, head and neck cancer, and kidney cancer. The main goals are to check safety and find the right dose. About 552 people…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Asher Biotherapeutics, Inc. • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Shorter radiation after head and neck cancer surgery may ease side effects
Disease control OngoingThis study tests whether giving fewer, larger doses of radiation after surgery for head and neck cancer is safe and helps patients keep their ability to swallow. About 59 adults with certain types of head and neck cancer will take part. The goal is to see if this shorter radiatio…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Cancer drug trial pulled before it even started
Disease control TerminatedThis trial aimed to see if the drug TTI-101 could shrink HPV-negative head and neck cancers when given just before planned surgery. It was designed for people with stage II to IV cancer that could be removed. However, the study was withdrawn before enrolling any participants, so …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Custom-Made vaccine targets tough cancers in early trial
Disease control TerminatedThis early-phase trial tested a personalized vaccine (PANDA-VAC) made from a patient's own tumor markers, given alongside the immunotherapy drug pembrolizumab. It involved 6 adults with advanced squamous lung or head/neck cancers that could not be cured. The main goal was to chec…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Immune cells take on head and neck cancer in early trial
Disease control OngoingThis early-phase study tests a new treatment called TBio-4101, which uses a patient's own immune cells (TILs) to fight advanced head and neck cancer. Participants receive these cells along with pembrolizumab, with or without chemotherapy. The main goal is to check safety in a sma…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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New drug combo aims to boost head and neck cancer treatment
Disease control OngoingThis study tests whether adding two drugs, pembrolizumab and olaparib, before and after standard chemoradiation can help people with locally advanced head and neck cancer live longer without the disease getting worse. About 45 adults will take part. The goal is to see if this com…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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New microscope could spot cancer cells Mid-Surgery
Diagnosis OngoingThis study tests a special microscope that lets doctors check for leftover cancer cells right during surgery. It involves 42 adults with skin or head-and-neck cancers. The goal is to see if this quick method matches standard lab tests.
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Institut de Cancérologie de Lorraine • Aim: Diagnosis
Last updated May 13, 2026 16:04 UTC
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New drug combo studied in head and neck cancer before surgery
Knowledge-focused OngoingThis study looks at how a protein called AXL in head and neck tumors responds to a combination of two drugs, imatinib and cetuximab, given before standard treatment like surgery or radiation. About 15 adults with head and neck cancer will receive the drugs for a short time, then …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Saliva and blood tests could reveal head and neck cancer secrets
Knowledge-focused OngoingThis study collects saliva, blood, and tissue samples from 225 adults with or without head and neck cancer. Researchers are searching for tiny genetic markers called miRNAs that might help predict how the disease will behave or aid in diagnosis. The goal is to improve future trea…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC