Lab-Grown immune cells take on head and neck cancer
NCT ID NCT06236425
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests a new approach for advanced head and neck cancer that has stopped responding to standard treatments. Doctors take a patient's own tumor-fighting immune cells (TILs), grow more of them in a lab, and give them back along with the immunotherapy drug Keytruda. The study includes only 7 patients and focuses on safety, not yet on effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TBio-4101 (a patient's own immune cells grown in a lab) plus pembrolizumab (Keytruda) with or without chemotherapy
What this could lead to
If it works, this could point toward a new treatment option for advanced head and neck cancer that has stopped responding to standard therapy.
What could go wrong
This is a very early, small safety study with only 7 patients. The treatment involves strong chemotherapy and immune-boosting drugs, which can cause serious side effects. Success is uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Moffitt Cancer Center
Tampa, Florida, 33612, United States