New personalized vaccine aims to keep head and neck cancer from returning
NCT ID NCT04183166
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new personalized immunotherapy called TG4050 for people with advanced head and neck cancer. The treatment is designed to train the immune system to recognize and attack each patient's unique tumor mutations. The goal is to see if it is safe and can help prevent the cancer from coming back after standard treatment. About 80 participants will be randomly assigned to receive TG4050 or no additional treatment.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Aintree University Hospital NHS Fondation Trust
Liverpool, L9 7AL, United Kingdom
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Complejo Hospitalario Universitario de Santiago
Santiago de Compostela, 15076, Spain
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Hospital Clínico San Carlos
Madrid, 28040, Spain
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Hospital Regional Universitario de Málaga - Hospital Civil
Málaga, 29010, Spain
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Hospital Universitari Vall d Hebrón
Barcelona, 08035, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hôpital Saint André - CHU de Bordeaux
Bordeaux, 33000, France
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Hôpital de la Timone
Marseille, 13000, France
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IUCT Toulouse
Toulouse, 31100, France
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Institut Català d Oncologia - Hospital Duran i Reynals
Barcelona, 08908, Spain
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Institut Curie
Paris, 75005, France
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Institut Gustave Roussy
Villejuif, 94805, France
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Mayo Clinic Jacksonville
Jacksonville, Florida, 32224, United States
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NHS Clatterbridge Cancer Center
Liverpool, L7 8YA, United Kingdom