Transgene

This study tests a new personalized immunotherapy called TG4050 for patients with advanced head and neck cancer. The treatment is designed to train the immune system to recognize and attack each patient's unique cancer mutations. The goal is to see if it is safe and can help prev…

This study tests whether combining two drugs—TG4001 (a vaccine-like therapy) and avelumab (an immunotherapy)—can shrink tumors or slow disease in people with advanced HPV-16 cancers (cervical, anal, penile, vulvar, or vaginal). About 143 adults whose cancer has spread or returned…