New study explores drug Combo's effect on head and neck tumors before surgery

NCT ID NCT05816785

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study looks at how a protein called AXL in head and neck tumors responds to a combination of two drugs, imatinib and cetuximab, given before standard treatment. About 15 adults with head and neck cancer will receive the drugs for a short time between diagnosis and surgery or radiation. The main goal is to measure changes in tumor cell activity, not to treat the cancer directly.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

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