New drug combo aims to improve head and neck cancer outcomes
NCT ID NCT05366166
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding two drugs, pembrolizumab and olaparib, before and after standard chemoradiation can help control locally advanced head and neck cancer. About 45 adults with this cancer will receive the drug combination. The main goal is to see if this approach improves the time people live without their cancer growing back.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Indiana University Simon Comprehensive Cancer Center
Indianapolis, Indiana, 46202, United States
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Medical University of South Carolina (MUSC)
Charleston, South Carolina, 29425, United States
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UNC Lineberger
Chapel Hill, North Carolina, 27514, United States
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University of Louisville, Brown Cancer Center
Louisville, Kentucky, 40202, United States