Less neck surgery may be just as effective for oral cancer with one affected node

NCT ID NCT07717307

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This trial tests whether removing fewer lymph nodes from the neck (selective dissection, levels I-IV) works as well as the standard more extensive removal (modified dissection, levels I-V) in people with oral cancer that has spread to a single lymph node. The goal is to see if the less invasive surgery can control cancer recurrence just as well while improving shoulder function and quality of life. About 80 participants will be randomly assigned to one of the two surgeries and followed for three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Selective neck dissection (levels I-IV) or modified neck dissection (levels I-V) surgery
What this could lead to
If successful, this trial could show that a less extensive neck surgery is just as effective at controlling cancer while causing fewer side effects and better quality of life.
What could go wrong
This is a relatively small, single-center trial, and results may not apply to all patients. The less extensive surgery might not control cancer as well in some cases.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms Mouth Neoplasms oral cavity squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kolhapur Cancer Centre

    Kolhāpur, Maharashtra, 416004, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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