New combo therapy aims to boost immune attack on hard-to-treat cancers
NCT ID NCT03589339
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times
Summary
This early-phase study tests a new drug called NBTXR3, which is injected into tumors and activated by radiation. It is combined with an immunotherapy (anti-PD-1) to see if it can help the immune system fight advanced cancers better. About 145 adults with various advanced solid tumors (like head and neck, lung, or liver cancer) are participating. The main goal is to check safety and find the best dose.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Christus St. Vincent Regional Cancer Center
Santa Fe, New Mexico, 87505, United States
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Emory University
Atlanta, Georgia, 30308, United States
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Gabrail Cancer Center
Canton, Ohio, 44718, United States
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Henry Ford Cancer Institute
Detroit, Michigan, 48202, United States
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Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland, 21287, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northwell Health
Manhasset, New York, 11030, United States
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Sanford Cancer Center
Sioux Falls, South Dakota, 57104, United States
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St Luke's University Health Network
Bethlehem, Pennsylvania, 18015, United States
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University of California San Francisco
San Francisco, California, 94158, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of North Carolina, School of Medicine
Chapel Hill, North Carolina, 27516, United States
Conditions
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