METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Clinical trials for METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA explained in plain language.
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New hope for tough breast cancer: trial tests pill to boost standard treatment
Disease control Recruiting nowThis early-stage trial is testing the safety and best dose of a new oral drug, ASTX727, when added to standard chemotherapy and immunotherapy for patients with metastatic triple-negative breast cancer. The study aims to see if this combination can shrink or control tumors better …
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists test novel drug duo in fight against Tough-to-Treat cancers
Disease control Recruiting nowThis early-phase study aims to find a safe and tolerable dose of a new drug combination for people with advanced breast cancer and other solid tumors that have a protein called HER2. The trial will test pidnarulex, which aims to stop tumor cell growth, together with an existing t…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New vaccine trial aims to train immune system to fight breast cancer in the brain
Disease control Recruiting nowThis study is testing a two-part treatment for breast cancer that has spread to the brain. Patients receive a personalized vaccine made from their own immune cells, combined with an immunotherapy drug called pembrolizumab. The goal is to see if this combination can shrink brain t…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Scientists test Custom-Made vaccine to fight spreading breast cancer
Disease control Recruiting nowThis study is testing whether adding a personalized vaccine to standard immunotherapy and chemotherapy helps control advanced triple-negative breast cancer that has spread. It will compare two groups of about 70 patients total: one gets the vaccine plus standard drugs, the other …
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Can a smartphone app help cancer patients live better and stay out of the hospital?
Disease control Recruiting nowThis study is testing whether adding a digital health app to standard cancer care helps patients with advanced triple-negative breast cancer. About 472 patients starting their first treatment will either use the app to report symptoms and get advice or receive standard care alone…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: NA • Sponsor: UNICANCER • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New hope for Tough-to-Treat breast cancer: old drugs, new combo
Disease control Recruiting nowThis study is testing whether combining two existing drugs—tamoxifen and a special form of doxorubicin—can help control advanced triple-negative breast cancer that has spread or cannot be removed by surgery. It is for patients whose cancer has continued to grow despite at least t…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Doctors test custom cancer vaccine to train immune system
Disease control Recruiting nowThis early-stage trial is testing a new, personalized vaccine for triple-negative breast cancer (TNBC). The vaccine is custom-made from a piece of a patient's own tumor and is designed to teach their immune system to recognize and attack the cancer. Researchers are studying the v…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New vaccine trial aims to train immune system to fight aggressive breast cancer
Disease control Recruiting nowThis study is testing whether a new vaccine called STEMVAC, when given alongside standard chemotherapy, can help control advanced triple-negative breast cancer. The vaccine is designed to teach the body's immune system to recognize and attack cancer cells. Researchers will enroll…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Scientists test Triple-Threat attack on tough breast cancer
Disease control Recruiting nowThis early-stage trial is testing the safety of a new three-drug combination for people with advanced triple-negative breast cancer. It combines a new experimental pill (ZEN003694) with an immunotherapy drug (pembrolizumab) and a standard chemotherapy (nab-paclitaxel). The main g…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Common drug ivermectin tested in new fight against aggressive breast cancer
Disease control Recruiting nowThis early-stage study is testing whether adding the drug ivermectin to standard immunotherapy helps shrink tumors in people with advanced triple-negative breast cancer that has spread. The main goals are to find a safe dose and see if the combination is more effective than immun…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Yuan Yuan • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New drug duo targets aggressive breast Cancer's weak spots
Disease control Recruiting nowThis early-stage trial is testing the safety and effectiveness of combining two drugs, neratinib and ruxolitinib, for a difficult-to-treat form of breast cancer. It is for people whose triple-negative breast cancer has spread and returned to the chest wall after previous chemothe…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Tracking promising cancer drugs in real patients
Knowledge-focused Recruiting nowThis study aims to collect real-world information about how well FDA-approved antibody-drug conjugate (ADC) treatments work for people with advanced HER2-negative breast cancer. Researchers will follow 100 patients receiving these treatments as part of their regular care to under…
Matched conditions: METASTATIC TRIPLE-NEGATIVE BREAST CARCINOMA
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC