New combo therapy offers hope for Hard-to-Treat breast cancer

NCT ID NCT06434064

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 31 times

Summary

This study tests whether combining tamoxifen (a hormone blocker) with a targeted form of chemotherapy (liposomal doxorubicin) can shrink tumors in people with advanced triple-negative breast cancer that has spread or cannot be removed by surgery. The trial enrolls 30 adults who have already tried at least two other treatments and have a specific TP53 gene change. The goal is to see how well the combination works and what side effects occur.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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