Custom-Made vaccine takes on aggressive breast cancer
NCT ID NCT06324240
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing a personalized vaccine made from a patient's own tumor, given alone or with immune-boosting drugs (pembrolizumab or ipilimumab), for triple negative breast cancer. The goal is to see if the vaccine is safe and can train the immune system to attack cancer cells. About 18 people with various stages of the disease will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized tumor membrane vesicle (TMV) vaccine, pembrolizumab, ipilimumab
- What this could lead to
- If it works, this could lead to a new way to train the immune system to fight triple negative breast cancer and reduce the chance of it coming back.
- What could go wrong
- This is a very early phase I trial with only 18 participants, so it is primarily testing safety and dosing. The vaccine is personalized and complex, so results may not apply to all patients, and side effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANATOMIC STAGE I BREAST CANCER AJCC V8 are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Emory Saint Joseph's Hospital
RECRUITINGAtlanta, Georgia, 30342, United States
Contact Email: •••••@•••••
Contact
-
Emory University Hospital Midtown
RECRUITINGAtlanta, Georgia, 30308, United States
Contact Email: •••••@•••••
Contact
-
Emory University Hospital/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Email: •••••@•••••
Contact
-
Grady Health System
RECRUITINGAtlanta, Georgia, 30303, United States
Contact Email: •••••@•••••
Contact
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A remote diet and exercise program aims to help rural cancer survivors shed pounds and lower recurrence risk
- Engineered immune cells join chemo and antibody to attack Hard-to-Treat breast cancer
- Can a vaccine train the immune system to hunt down hidden breast cancer cells?
- Could a common cholesterol drug boost breast cancer treatment?
- Strawberry compound could help breast cancer survivors walk farther
- Strawberry compound and exercise may keep breast cancer survivors from becoming frail