Emory University

This early-stage trial tests a personalized vaccine made from a patient's own tumor, given alone or with drugs that boost the immune system (pembrolizumab or ipilimumab). The goal is to see if the vaccine is safe and can help the immune system fight triple negative breast cancer …

This study looks at whether a single booster dose of a meningitis B vaccine can protect young adults who already received a different meningitis B vaccine years ago. Researchers will measure immune responses in 125 healthy participants to see how many are protected against four k…

This study tests whether a year-long maintenance treatment with sirolimus and low-dose chemotherapy can help prevent cancer from coming back in children and young adults (ages 1 to 30) with high-risk solid tumors. Participants take daily sirolimus and twice-daily celecoxib along …

This study tests whether a microbiome therapy (a treatment that changes the bacteria in your gut) can safely reduce the amount of antibiotic-resistant bacteria living in the intestines of hospitalized patients. About 40 adults who carry these superbugs will receive either the the…

This early-phase trial tests a combination of two drugs, cabozantinib and enfortumab vedotin, in people with advanced bladder cancer that has spread or cannot be removed. The goal is to find the best dose and see if the combo is safe and shrinks tumors. About 32 adults who have a…

This study tests whether giving a special mix of gut bacteria (microbiota therapy) can safely reduce the amount of drug-resistant superbugs living in the gut. About 60 adults who carry these resistant bacteria will either receive the therapy or just be watched. The goal is to see…

This study tests a drug called zanidatamab given before surgery for people with HER2-positive colorectal cancer that has not spread widely. The goal is to see if the drug can shrink tumors and improve outcomes. About 38 adults will take part, and the study is currently recruiting…

This study looks at whether mindfulness meditation can improve nerve function in people with chronic kidney disease (CKD). It also tests if adding a gentle nerve stimulation device can boost these benefits. The goal is to help control blood pressure and restore balance in the bod…

This early-phase trial tests a new drug called tegavivint combined with the chemotherapy gemcitabine in people whose osteosarcoma (a type of bone cancer) has returned or not responded to treatment. The main goal is to find the safest dose of the combination and see if it can cont…

This study aims to make opioid use disorder treatment more available in rural Georgia by having emergency room doctors connect patients to addiction specialists at the Georgia Poison Center through video calls. About 480 adults who come to the ER with opioid withdrawal or overdos…

This study is testing a shorter course of high-dose radiation (proton or photon) for people with non-cancerous brain tumors like meningiomas, pituitary adenomas, and schwannomas. The goal is to see if this approach can control tumor growth while reducing side effects and making t…

This early-stage study tests whether infusions of donated neonatal stem cells are safe for young adults and children with dilated cardiomyopathy, a condition where the heart is enlarged and weak. Researchers will monitor for serious side effects and check if the treatment improve…

This study tests whether adding high-dose radiation to standard immunotherapy (pembrolizumab) and chemotherapy can help people with a specific type of advanced breast cancer (PD-L1 positive, triple-negative) that has spread. About 29 adults will receive the combination treatment.…

This study tests whether combining two drugs, cabozantinib and pembrolizumab, can shrink or slow the growth of advanced adrenal cancer that has spread or cannot be removed by surgery. The trial enrolls 21 adults with this rare cancer, regardless of prior treatments. The goal is t…

This study looks at how Palynziq, a medication for phenylketonuria (PKU), improves diet, brain function, and nutrition. PKU is a genetic disorder that makes it hard to break down an amino acid called phenylalanine, which can build up and cause brain damage. The study will follow …

This study looks at whether giving regular blood transfusions to pregnant women with sickle cell disease can reduce serious health problems for both mother and baby. About 50 women will be randomly assigned to receive either repeated transfusions or standard care during pregnancy…

This study tests whether using digital checklists and reminders in cardiology clinics can increase the use of guideline-recommended heart failure medications. About 4,000 adults with heart failure and reduced ejection fraction will take part. The goal is to improve medication use…

This study is for children aged 5 to nearly 17 who were admitted to the intensive care unit for asthma. Researchers want to see if a personalized asthma navigator program, which helps families manage asthma at home, can reduce future emergency visits. The program will be tested w…

This study tests a combination of two drugs, acalabrutinib and obinutuzumab, in people with untreated, slow-growing types of non-Hodgkin lymphoma, including follicular lymphoma. The goal is to see if this drug pair can shrink or eliminate cancer. About 49 adults will take part. T…

This study looks at whether early, minimally invasive surgery to remove blood from a deep brain bleed helps patients more than standard medical care. About 600 adults aged 18-70 with a specific type of brain bleed will be enrolled. The goal is to see which approach leads to bette…

This study looks at whether a low, personalized dose of aPCC (FEIBA) can safely help blood clot in children and adults with hemophilia A who have inhibitors and are already taking emicizumab. Researchers will measure how well the blood clots after the dose and track any serious s…

This study compares two hormone therapy combinations (leuprolide or relugolix plus abiraterone acetate) in men with advanced prostate cancer who are also getting radiation. The goal is to see which combination causes less harm to the heart, since these treatments can raise blood …

This early-phase trial tests whether adding a precise external radiation treatment (SBRT) before a standard radioactive drug therapy (177Lu-DOTATATE) is safe and works better for people with large, inoperable digestive neuroendocrine tumors. About 15 adults whose tumors have grow…

This study tests an investigational drug called eptacog beta for people with Glanzmann Thrombasthenia, a rare inherited bleeding disorder. Over 9 months, 6 participants will use the drug to treat serious bleeding episodes, and some may choose an extra 6-month phase to prevent ble…

This study compares a continuous glucose monitor (Dexcom G7) to standard finger-stick blood sugar tests in 100 hospitalized adults with poorly controlled type 1 diabetes. The goal is to see which method keeps blood sugar in a safe range (70-180 mg/dl) and prevents dangerously low…

This early-phase study tests whether combining an immunotherapy drug (atezolizumab) with precise radiation and surgery is safe for people whose osteosarcoma has come back in the lungs. About 12 participants will receive the treatment to find the best dose and check for side effec…

This early-stage trial tests a personalized vaccine made from a patient's own tumor cells, alone or with the immunotherapy drug pembrolizumab, for head and neck cancer that has returned or spread. The goal is to find the safest dose and see if the vaccine helps the immune system …

This study tests two tools to help Black patients with advanced kidney disease get timely care and possibly delay the need for dialysis. Researchers will use a computer alert system and health coaching to connect patients to specialists. The goal is to slow kidney decline, reduce…

This study tests whether adding diclofenac, a common anti-inflammatory painkiller, can help control tumor growth in people with advanced non-small cell lung cancer whose disease is starting to worsen while on immunotherapy alone. About 20 adults with stage III or IV lung cancer w…

This study tests proton beam radiation in 20 adults with non-small cell lung cancer that has spread to chest lymph nodes and has been surgically removed. The goal is to see if this precise radiation kills leftover cancer cells while sparing healthy tissue, reducing the chance of …

This study tests whether giving arginine, a natural protein, can improve energy production in cells of children hospitalized with COVID-19. About 21 kids aged 3 to 21 will receive one of three doses of arginine three times a day for up to five days. Researchers will measure chang…

This study tests whether a combination of three drugs—belantamab, pomalidomide, and dexamethasone—can keep high-risk myeloma from returning after a stem cell transplant. About 34 adults who have already had a transplant and are in partial remission or better will take these drugs…

This study tests whether adding celecoxib (a pain reliever) to standard immunotherapy drugs (durvalumab and tremelimumab) can help control advanced liver cancer that has spread. About 39 adults with advanced or metastatic hepatocellular carcinoma will receive the combination. The…

This study tests a new drug (MRX-2843) combined with a standard treatment (osimertinib) in people with advanced EGFR-mutant non-small cell lung cancer. The goal is to find the safest dose and see how well the combination works. About 69 participants will take part in this early-p…

This study tests whether adding the cholesterol-lowering drug lovastatin to the immunotherapy pembrolizumab can shrink tumors in people with head and neck cancer that has returned or spread. About 28 adults whose cancer has a specific marker (PD-L1 CPS≥1) will receive both drugs.…

This study is testing whether giving immunotherapy drugs (ipilimumab and nivolumab) in the morning works better than giving them later in the day for people with advanced melanoma that cannot be removed by surgery. About 99 adults with stage IV melanoma will be randomly assigned …

This early study tests the safety of a wearable device called Optune that creates low-intensity electric fields to disrupt cancer cell division. Ten adults with brainstem gliomas will wear the device to see if it can slow tumor growth or shrink the cancer. The goal is to find a n…

This study tests whether the immunotherapy drug toripalimab can lower the chance of cancer coming back after surgery in people with a specific type of high-risk colon cancer (mismatch repair deficient). About 40 participants will receive the drug for up to a year. The main goal i…

This study tests whether a program led by community health workers can help migrant farmworker women ages 18-45 reduce stress, feel less isolated, and improve heart health. Participants will either receive peer support and help finding community resources, or just basic health in…

This study tests a precise type of radiation called proton therapy for men with high-risk prostate cancer that has spread to lymph nodes. The goal is to see if targeting the tumor and nearby lymph nodes causes fewer bowel and bladder side effects than standard radiation. About 30…

This early study tests whether adding low-dose IL-2 to the immunotherapy drug pembrolizumab can better activate the immune system against stage IV non-small cell lung cancer. About 15 people with untreated advanced lung cancer will receive the combination. The goal is to see if t…

This study tests whether a single dose of azithromycin can clear N. meningitidis bacteria from the nose and throat of college students. About 1,120 participants will provide samples before and after taking the antibiotic. The goal is to see if this approach can reduce the spread …

This study tests whether giving a combination of three chemotherapy drugs (gemcitabine, cisplatin, and nab-paclitaxel) before surgery can help shrink pancreatic tumors and improve outcomes. About 36 adults with pancreatic cancer that can be surgically removed will participate. Th…

This study tests a combination of two targeted drugs (defactinib and avutometinib) plus an immunotherapy (nivolumab) in 50 people with advanced LKB1-mutant lung adenocarcinoma that has stopped responding to standard anti-PD1 treatment. The goal is to see if this triple therapy ca…

This study tests a drug called iberdomide, alone or with dexamethasone, in people with smoldering multiple myeloma at intermediate or high risk of developing active cancer. The goal is to see if the treatment can shrink or control the cancer cells and delay progression to symptom…

This study is for children with neuroblastoma or osteosarcoma that has come back or not responded to treatment. It tests a new approach: giving donor immune cells (gamma delta T cells) along with standard chemotherapy and an antibody drug. The main goal is to find the safest dose…

This study tests whether atovaquone, a drug normally used for infections, can help people with a type of ovarian cancer that no longer responds to standard platinum chemotherapy. About 28 adults with this resistant cancer will take atovaquone to see if it slows tumor growth. The …

This study looks at whether a simple blood test can help doctors decide if a head CT scan is needed for people with mild head injuries. Researchers will collect blood samples from 350 adults and see if the test results match the need for imaging. The goal is to reduce unnecessary…

This study is testing a new, non-invasive imaging device called qOBM that uses red light to look at skin lesions. The goal is to see if it helps doctors diagnose skin cancer more accurately without needing a biopsy. Ten adults with skin lesions will be scanned, and the images wil…

This study checks if a smartwatch can spot an irregular heartbeat (atrial fibrillation) in 500 older adults who had a stroke with an unknown cause. Participants wear a study smartwatch and a standard heart monitor for 30 days. Researchers compare the smartwatch data to the standa…

This study aims to see if a portable eye-tracking device can accurately screen 9-month-old infants for autism spectrum disorder (ASD) and other developmental delays. Researchers will test over 2,000 babies and follow them until age 2 to confirm diagnoses. If successful, this tool…

This study tests a program to help families in rural tribal communities make their homes smoke-free, reducing exposure to secondhand smoke. About 575 adults who smoke or live with a smoker and don't already have a smoke-free home will take part. The goal is to see if the program …

This study tests whether in-person acupuncture or virtual acupressure can prevent joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It focuses on Non-Hispanic Black postmenopausal women with early-stage breast cancer, who are more likely to st…

This study tests whether a long-lasting painkiller called EXPAREL works better than the standard bupivacaine for pain after total ankle replacement. About 104 adults having ankle surgery will receive one of the two drugs as a nerve block. The goal is to see which provides better …

This study tests a nerve block called ganglion impar neurolysis to reduce pain caused by radiation therapy for anal cancer. About 5 adults with localized anal cancer who report high pain scores will receive the injection near the tailbone. The goal is to see if this procedure can…

This study tests whether playing online games with others can help older adults (ages 50-85) feel more socially connected and less lonely. It includes people with and without mild cognitive impairment (MCI). Participants will play games remotely and report changes in loneliness, …

This study compares two sequences of active therapy delivered via telemedicine to standard care in infants aged 4-13 months with cerebral palsy or high risk. The goal is to improve arm movement and parenting skills. Researchers will measure changes in fine motor function and pare…

This study looks at whether giving teenagers extra doses of a steroid called dexamethasone after scoliosis surgery can reduce pain, nausea, and time in the hospital. About 50 teens aged 10-18 will be randomly assigned to receive either the standard single dose or three additional…

This study tests whether taking oral progesterone can reduce psychological distress and improve sleep, breast development, and quality of life in transgender women. About 40 participants who have been on hormone therapy for at least 6 months will take progesterone or a placebo. T…

This study tests whether a single dose of MDMA (the drug in ecstasy) can make a two-week intensive exposure therapy more effective for adults with PTSD. About 200 participants will receive either MDMA or a placebo during therapy, and their PTSD symptoms will be measured one month…

This study tests if a safe, non-invasive brain stimulation technique called tDCS can reduce chronic pain in 100 military members and veterans. Participants will use a head device at home while continuing their usual care. The goal is to see if this adds extra pain relief and impr…

This study tests whether L-DOPA, a drug used for Parkinson's, can help people with depression who have high inflammation and lose interest in activities. Seventy adults aged 25-55 will receive either L-DOPA or a placebo for 8 weeks. Researchers will track mood, motivation, and br…

This study tests an online course called CAN-DO designed to help family members caring for someone with dementia. 270 caregivers will take the course either right away or after a wait, and complete surveys over 6 months. The goal is to see if the course reduces stress and improve…

This study tests whether a 6-day low-dose steroid (Medrol Dosepak) can help reduce pain, nausea, and the need for opioid painkillers after foot or ankle surgery. About 180 adults having surgery at Emory will take either the steroid or a placebo. The goal is to see if this simple,…

This study tests whether a non-invasive device that stimulates the vagus nerve can reduce withdrawal symptoms in people with opioid use disorder. About 103 participants will stay in the hospital for one week, receive the stimulation or a sham, and complete surveys and brain scans…

This study tests a web-based program designed to help colorectal cancer patients on chemotherapy and their caregivers manage common symptoms like fatigue, depression, sleep problems, pain, and brain fog. About 56 patient-caregiver pairs will use the online tool and report how wel…

This study is testing whether different types of therapy, including body-focused and non-body focused approaches, can reduce symptoms of dissociation in people who have experienced trauma. Researchers will study brain activity and use questionnaires to see if these therapies impr…

This study tests a virtual group program that teaches teens with IBD coping skills and uses heart rate biofeedback to help manage stress. About 128 participants aged 13-18 will be randomly assigned to the program or a waitlist. The goal is to see if the program reduces anxiety, d…

This study tests a group training program called I-STRONG for teens with sickle cell disease who have chronic pain. The program teaches skills to strengthen both mind and body, with the goal of improving everyday functioning and reducing pain symptoms. About 155 teens and their p…

This study looks at whether releasing the pectoralis minor muscle during reverse shoulder replacement helps reduce pain and improve arm movement. About 90 adults having this surgery will be randomly assigned to either have the muscle released or not. Researchers will compare pain…

This study tests whether a personalized exercise program done at home via Zoom can help gynecologic cancer survivors manage symptoms like pain, fatigue, sleep problems, and brain fog. Researchers will enroll 40 women who have finished cancer treatment. The goal is to see if the p…

This early-phase study tests whether giving palliative radiotherapy together with the drug lurbinectedin is safe for people with extensive-stage small cell lung cancer that has spread beyond the chest. The goal is to relieve cancer symptoms without causing too many side effects. …

This study looks at whether slowly lowering the dose of the steroid dexamethasone after brain tumor surgery can reduce side effects like high blood sugar and slow wound healing. About 200 adults with certain brain tumors will be randomly assigned to either a standard steroid tape…

This study tests whether a 12-week virtual physical therapy program is practical and helpful for children and young adults (ages 8–23) who are at least 100 days past a bone marrow transplant. Participants will have twice-weekly online sessions with a physical therapist and receiv…

This study tests whether a pain management plan that limits opioid use after hip replacement surgery can reduce how many opioids patients take while still controlling pain well. About 120 adults getting a hip replacement for osteoarthritis will be randomly assigned to either the …

This study tests a program called CARE-D-Foot-Nav, which provides a patient navigator to help adults with diabetic foot ulcers manage their care. The goal is to see if this extra support leads to more wounds healing completely within 20 weeks compared to usual care. The study wil…

This study tests a home-based, web program that helps stroke survivors and their family caregivers work together on arm exercises. The goal is to improve the survivor's arm function and daily activity while also reducing caregiver stress. About 220 participants (survivors and the…

This study tests whether having a personal pain coach helps people aged 15-45 recover better after orthopedic surgery for sports injuries like ACL tears. Coaches teach non-drug pain management skills like mindfulness and help coordinate care. 150 participants will either work wit…

This study tests whether a low dose of naltrexone (LDN) can reduce chronic nerve pain in people with HIV. About 60 adults with HIV and neuropathic pain will take LDN for 12 weeks while researchers track pain scores and CD4 counts. The goal is to find a safer, non-opioid option fo…

This study looks at 200 infants under 1 year old who had heart surgery for congenital heart disease. After surgery, when the breathing tube is removed, babies need extra help breathing. This study compares two standard methods—high flow nasal cannula and non-invasive positive pre…

This study tests if a safe, non-drug device called Alpha-Stim can reduce pain and other symptoms in veterans with Gulf War Illness. About 130 veterans aged 40-80 will receive the gentle electrical stimulation and have their brain activity measured with MRI scans. The goal is to s…

This study tests a small device that stimulates nerves in the ear to see if it can safely and effectively reduce pain in children with sickle cell disease during a pain crisis. About 20 children hospitalized for a sickle cell pain crisis will use the device. The goal is to see if…

This study tests whether baricitinib, a drug that blocks inflammation signals, can improve motivation and brain function in adults with major depression who have high inflammation. About 100 people aged 25-55 with depression and elevated C-reactive protein will receive the drug o…

This study tests whether listening to music with a strong beat helps older adults with mild memory problems exercise more and keep their minds sharp. Eighty volunteers aged 65 and older will do strength and aerobic training for 6 months, some with special music and some without. …

This study is testing a new community-based program to help Black transgender women who experience ongoing stigma. The program aims to reduce symptoms of stress, anxiety, and depression. Researchers will work with 40 participants to see if the program is helpful and practical.

This study tests a 6-week video program that teaches sleep-improving skills to older adults with memory loss or dementia and their care partners. Researchers want to see if the program is practical and helpful for improving sleep, mood, and daily life. About 80 pairs (person with…

This study is testing a phone-based system that helps people with heart failure monitor their symptoms and get real-time coaching on how to manage them at home. The goal is to see if this approach improves patients' ability to care for themselves and recognize warning signs. Rese…

This study tests whether a 12-week sleep improvement program can help adults with type 1 diabetes sleep better and manage their blood sugar. Researchers will enroll 300 people aged 18-40 who have had type 1 diabetes for at least one year and have poor sleep. The program uses coun…

This study compares two premedication regimens—methylprednisolone versus dexamethasone—to prevent allergic reactions to motixafortide in multiple myeloma patients undergoing stem cell collection. About 94 adults will participate to see which steroid works better and has fewer sid…

This study tests a short online program for people who have recently become caregivers for a friend or family member with dementia. The program teaches skills to manage symptoms, find support, and handle medications. Researchers want to see if it helps caregivers feel more in con…

This study looks at whether mindfulness training can improve recovery for college athletes after sports injury surgery. About 40 student-athletes will either receive mindfulness training or standard care. Researchers will measure pain, physical function, and mental health to see …

This study tests whether giving the chemotherapy drug oxaliplatin over 6 hours instead of the usual 2 hours can prevent or delay nerve damage in people with gastrointestinal cancers. About 60 participants will be randomly assigned to one of the two infusion times. The goal is to …

This study looks at how different ways of delivering voice therapy affect communication over 12 months. It involves 120 people with voice problems like muscle tension dysphonia or vocal fold lesions. Researchers will compare therapy methods to see which leads to clearer speech an…

This study is testing whether a 12-week, home-based exercise program delivered virtually can help improve memory, attention, and thinking problems in adolescent and young adult brain tumor survivors. Researchers will enroll 60 participants to compare the exercise program against …

This study looks at whether doing handgrip exercises at home for 8 weeks can help lower blood pressure in people with chronic kidney disease (stages 3 and 4). About 50 adults aged 45-85 who do not exercise regularly will take part. Researchers will measure blood pressure, artery …

This study follows children under 21 who have a genetic condition that raises their risk of cancer, along with their relatives. Researchers collect health data and samples to better understand how these cancers develop and how to catch them early. The goal is to improve monitorin…

This study looks at why people with chronic kidney disease (CKD) have trouble exercising and tests ways to improve their fitness. Researchers will measure changes in exercise capacity and blood pressure in 156 participants, including CKD patients, kidney transplant recipients, an…

This study gives healthy adults the flu virus in a controlled hospital setting to closely watch how the immune system fights it and how the virus spreads. The goal is to learn more about the flu so we can create better vaccines and medicines. Participants stay in the hospital for…

This study looks at how the immune system responds in people with early-stage triple negative breast cancer who are receiving standard chemotherapy combined with immunotherapy (pembrolizumab). Researchers will measure certain immune markers in blood and tissue samples to see if t…

This study aims to learn how the immune system reacts to the flu virus and how the virus spreads. Healthy adults aged 18-49 will be intentionally infected with a lab-made H3N2 flu virus in a controlled setting. The goal is to observe mild to moderate flu symptoms and track the vi…

This study uses small pieces of heart tissue removed during necessary heart surgery in children with congenital heart disease. Researchers want to learn how calcium helps heart cells control their contraction force and how this differs between infants and adults. They also aim to…

This study looks at how the amount of air in your lungs affects throat collapse during sleep in people with obstructive sleep apnea (OSA). Researchers will use a special camera to watch the throat while patients are sedated, and they will either use a chest ventilator or neck ele…

This study tests a new, non-invasive way to weaken fear memories shortly after a traumatic event. Researchers will use brain imaging and mild stimulation to see if they can disrupt how the brain stores scary memories. The goal is to lower the risk of developing PTSD. The study in…

This early-phase trial studies how to best give arginine (a natural amino acid) alongside whole brain radiation for people whose cancer has spread to the brain. Researchers will compare oral and IV arginine to find the dose that reaches the highest blood levels. The goal is to le…

This study looks at whether a camp that teaches teens and young women with PKU or MSUD about their condition and nutrition can improve their pregnancy outcomes and quality of life. Researchers will compare the results of women who attended the camp to those who did not. The study…

This study aims to find the best ways to help families in Cambodia switch from wood or charcoal stoves to electric induction stoves. Researchers will track stove use and measure indoor air pollution in 6,150 households across 65 villages. The goal is to see if this switch is affo…

This study explores why people with depression struggle with difficult choices. Researchers will use brain stimulation (TMS or TI) while 500 participants, including those with depression and healthy volunteers, play game-like tasks. The goal is to understand how brain regions lik…

This study uses special PET/CT scans to see how radiation therapy affects blood vessels in the neck of people with head and neck cancers. About 20 adults will get two types of PET scans before and after radiation. The goal is to compare the scans and learn more about radiation's …

This study looks at why people with bipolar disorder may think about or attempt suicide, focusing on life experiences and biology. Researchers will test a 6-week group program to help reduce these risks and improve quality of life. About 130 English-speaking adults with bipolar d…

This study looks at why people with PTSD often have higher risk for heart problems, focusing on an overactive 'fight-or-flight' nervous system. Researchers will test two daily therapies—a breathing technique (DGB) and a mild nerve stimulation device (tVNS)—over 8 weeks in 120 vet…

This study looks at how patients and doctors discuss immunotherapy, a type of cancer treatment. Researchers want to find out where patients get their information, what they understand, and how doctors explain it. They will also test if educational videos help patients learn more …

This study tests whether a special type of MRI (spectroscopic MRI) can help doctors better target proton therapy for children with aggressive brain tumors. The imaging maps tumor metabolism without needing contrast dye. About 25 children with high-grade glioma will be enrolled to…

This study looks at how the antibiotic doxycycline affects inflammation and the natural bacteria in the body for 200 people with HIV or taking HIV prevention medication (PrEP). Researchers want to see if doxycycline, already used to prevent STIs, has extra effects on inflammation…

This study looks at how well African American men newly diagnosed with early-stage prostate cancer understand what their doctor tells them about treatment options and side effects. Researchers will give some patients an easy-to-read educational handout after their doctor visit an…

This study tests whether combining prism adaptation training with electrical stimulation can improve spatial neglect (a condition where stroke survivors ignore one side of space) and walking problems. Researchers will measure changes in pointing behavior, brain activity, and walk…

This study tests a wearable stethoscope patch that listens to breath sounds in children aged 6-17 with asthma who are in the hospital for an attack. The patch is worn on the chest and back for up to 8 hours to detect wheezing. Researchers want to see if the device can reliably ca…

This study tests whether a group program called Compassion-Centered Spiritual Health Interventions for Teams can help cancer center staff feel less burned out and work better together. About 80 employees (nurses, doctors, and other staff) will either join the program or continue …

This study looks at whether drinking pasteurized milk that contains harmless, inactive pieces of the H5 flu virus could cause a positive flu test from a nose or throat swab. The goal is to help the CDC improve flu surveillance by understanding how milk consumption might affect te…

This study collects information from 735 Alzheimer's patients aged 50-90 who are receiving FDA-approved anti-amyloid antibody treatments as part of their regular care. Researchers will track changes in memory, thinking, and daily living skills over time. The goal is to learn how …

This study looks at how the placement and strength of deep brain stimulation (DBS) in the brain affects a person's ability to stop themselves from acting impulsively. Researchers will test 80 people with Parkinson's disease and healthy volunteers using computer tasks that measure…

This study tests different message styles sent through MyChart, a patient portal, to see which ones get more people interested in joining research studies. Up to 100,000 patients will receive these messages. The goal is to improve how researchers invite people to participate.

This study looks at how people with mild cognitive impairment (MCI) and Alzheimer's disease adjust their walking when conditions change, like walking on different surfaces. Researchers will measure walking patterns, memory, and thinking skills in 10 older adults. The goal is to b…

This study compares two different screening methods for PTSD in pregnant Black women to see which one better improves mental health, use of prenatal care, and birth outcomes. About 804 women in their first trimester who have experienced at least one traumatic event will take part…

This study looks at how the amount of nicotine and the pH level in nicotine pouches change how they feel, how much people like them, and how addictive they might be. About 84 young adults who already use nicotine pouches will test different products in a lab setting. The goal is …

This study looks at how mental stress affects the heart and blood vessels in postmenopausal women with coronary microvascular dysfunction (CMD), a condition where the heart's small arteries don't work properly, causing chest pain. Researchers will compare women with CMD to those …

This study compares a standard survivorship care plan to one that is tailored for people with lower health literacy. The goal is to see if the tailored plan helps African American prostate cancer patients better understand their treatment side effects and follow-up care. About 15…

This study aims to understand why some people with heart disease develop dangerous heart rhythms called ventricular tachycardia. Researchers will measure the electrical signals in heart tissue during a routine procedure to identify which areas trigger the abnormal rhythm. The goa…

This study watches how doctors treat men with hemophilia A whose bodies have developed antibodies (inhibitors) that block standard clotting factor. Researchers will track different treatment plans, including immune tolerance therapy and newer drugs like emicizumab, to see which w…

This study is for 80 adults with achalasia or similar swallowing problems. Researchers want to see how muscle scarring in the esophagus relates to how well the esophageal valve works. By understanding this better, they hope to find ways to treat the disease earlier.

This study tests a new, non-invasive wearable patch with a microphone that listens to swallowing sounds in people who have trouble swallowing after a stroke. Researchers will collect these sounds during a standard swallowing X-ray test and use machine learning to find patterns of…

This study looks at whether a family history screening program can help more women in rural public health clinics learn about their risk for BRCA-related breast and ovarian cancers. About 3,200 women over age 25 in Southwest Georgia will take part. The goal is to see if the progr…

This study looks at whether a balance exercise called IVA is safe and helpful for adults with vision problems, with or without inner-ear balance issues. Researchers will compare how people with only vision problems respond versus those with both vision and inner-ear problems. Par…

This study looks at whether offering hearing tests close to home or remotely can help more head and neck cancer patients get their hearing checked during and after treatment. Many patients on cisplatin chemotherapy or radiation may lose hearing, but traveling to the clinic for te…

This study looks at how the flu and COVID vaccines affect the immune system in people with different types of lymphoma. Researchers will measure antibody levels and immune cells over time, comparing them to people without lymphoma. The goal is to better understand how lymphoma an…

This study compares two training models for early intervention providers in Georgia to see which helps them better deliver Project ImPACT, an autism therapy for children under 3 with communication delays. About 80 providers and families will take part. The goal is to improve how …

This study tests a group program called Weyera that aims to improve mental health and resilience in Ethiopian and Eritrean young adults (ages 18-29) living in Atlanta. The program involves weekly 2-hour sessions over 8 weeks. The main goal is to see if the program is acceptable, …