Emory University

This study is testing how well two different meningitis B vaccines protect young adults who previously received a different meningitis B shot. Researchers want to see if a single dose of either vaccine boosts protection against four dangerous strains of meningitis bacteria. The s…

This study is testing whether proton radiation therapy can treat high-risk prostate cancer while causing fewer digestive and urinary side effects than traditional radiation. Researchers will treat 30 patients with advanced prostate cancer using precisely targeted proton beams tha…

This study is testing whether a drug called baricitinib, which reduces inflammation, can help improve symptoms of depression in people who have both depression and high levels of inflammation. About 100 adults with depression, low motivation, and a specific blood marker of inflam…

This early-stage study is testing whether combining two radiation-based treatments is safe and more effective for controlling large, inoperable neuroendocrine tumors in the digestive system. Participants first receive a highly focused, external radiation treatment, followed by a …

This study is testing whether a handheld device that gently stimulates a nerve in the neck can help people with opioid addiction. Participants stay in a hospital for about a week to see if the device safely reduces withdrawal symptoms and cravings. The goal is to see if this non-…

This early-stage study is testing the safety of a three-part treatment for osteosarcoma (a type of bone cancer) that has come back only in the lungs. The treatment combines a drug that helps the immune system fight cancer (atezolizumab), targeted radiation (SBRT), and surgery to …

This study is testing whether giving two immunotherapy drugs (ipilimumab and nivolumab) at specific times of day improves how well they work for advanced melanoma. Researchers want to see if receiving treatment in the morning, afternoon, or late afternoon leads to better survival…

This study is testing if mindfulness meditation can help calm an overactive nervous system in people with chronic kidney disease (CKD), which is linked to high blood pressure and heart risk. Researchers also want to see if a gentle, non-invasive device that stimulates a nerve in …

This study aims to find the best treatment for a severe type of stroke caused by a deep bleed in the brain. It will compare standard medical care in the ICU to a newer, less invasive surgery that quickly removes the blood clot. Researchers are enrolling 600 adults to see if the e…

This study aims to find a safer, personalized low dose of a clotting medication called FEIBA for children and adults with severe hemophilia A who are already taking emicizumab. Researchers want to see if this approach can effectively control bleeding while minimizing risks like b…

This study is testing if two simple, non-drug therapies can help calm an overactive nervous system in people with PTSD, which is linked to higher heart disease risk. Veterans with PTSD will use either a guided breathing device or a gentle neck stimulation device daily for 8 weeks…

This study is testing whether combining two existing drugs, cabozantinib and pembrolizumab, can help control advanced adrenal cancer. It is for adults whose cancer has spread or cannot be removed by surgery. The goal is to see if this combination can shrink tumors and stop the ca…

This study tests whether proton beam radiation therapy works better than standard radiation after lung cancer surgery. It aims to kill any remaining cancer cells while protecting healthy tissue, potentially reducing the chance of cancer returning. The trial will enroll 20 adults …

This study is testing if adding diclofenac, a common anti-inflammatory painkiller, can help control advanced lung cancer that is starting to get worse while patients are on standard immunotherapy. The goal is to see if diclofenac can slow tumor growth and make the immunotherapy w…

This study is testing whether a kidney health coaching program can help delay the need for dialysis or death in Black patients with advanced chronic kidney disease. The program involves six months of support from coaches who have personal experience with kidney disease. Researche…

This study aims to improve access to treatment for opioid addiction in rural Georgia. It connects patients in emergency rooms via video call to addiction specialists who can help start medication. The program also links patients to a recovery coach and local support services to h…

This is a first-in-human safety study testing a new type of donor immune cell therapy for children whose neuroblastoma or osteosarcoma has come back or hasn't responded to standard treatments. The main goal is to find the safest dose of these cells when given alongside a combinat…

This study tests whether a personalized asthma navigator program can help children avoid future hospital visits after being admitted to intensive care for asthma. Researchers will work with 75 children aged 5-16 to identify barriers to good asthma management and provide tailored …

This study is testing whether a new immunotherapy drug called iberdomide can delay or prevent a pre-cancerous blood condition from turning into active multiple myeloma. It will involve about 68 adults with intermediate or high-risk smoldering myeloma. Patients will receive iberdo…

This early study is testing whether giving patients the amino acid arginine alongside standard whole-brain radiation therapy is safe and might make the radiation work better against cancer that has spread to the brain. Researchers are comparing whether taking arginine by mouth or…

This study is testing whether transferring healthy donor gut bacteria to patients can reduce or eliminate dangerous, drug-resistant germs they carry. It involves 60 adults in long-term care facilities who are colonized with these germs. Participants will either receive the gut ba…

This study aims to find out which of two standard hormone therapy combinations is safer for the heart when treating advanced prostate cancer. It will enroll 72 men who are about to start radiation therapy and need hormone treatment. Researchers will use special heart scans and bl…

This study is testing whether adding the common cholesterol-lowering drug lovastatin to the immunotherapy drug pembrolizumab can better control head and neck cancer that has returned or spread. Researchers believe lovastatin may make cancer cells more vulnerable to the immune sys…

This early study is testing if adding a low-dose immune stimulant (IL-2) to a standard immunotherapy drug (pembrolizumab) can better fight advanced non-small cell lung cancer. The main goal is to see how this combination changes the patient's immune cells. Researchers will also c…

This study is testing whether a 'patient navigator' can help people heal their diabetic foot ulcers faster. A navigator is a coach who helps coordinate care, find resources, and overcome barriers after leaving the hospital. Researchers will compare healing rates over 20 weeks for…

This early-stage study is testing a new drug called tegavivint, combined with an existing chemotherapy (gemcitabine), for people whose osteosarcoma (a type of bone cancer) has come back or stopped responding to standard treatments. The main goal is to find the safest and most eff…

This study is testing whether atovaquone, a medication normally used to treat certain infections, can help control ovarian cancer that has stopped responding to standard platinum chemotherapy. It will involve 28 patients with this resistant form of cancer to see if the drug can s…

This study aims to find the best way to screen for PTSD (post-traumatic stress disorder) in Black women during early pregnancy. Researchers will compare two different screening approaches to see which one is more effective at reducing PTSD symptoms and improving pregnancy care. T…

This study is observing adults with PKU who are starting a new, FDA-approved drug called Palynziq. Researchers want to see how this treatment affects what people can eat, their brain function, nutritional status, and overall quality of life over three to five years. The goal is t…

This study is testing whether adding celecoxib, a common anti-inflammatory pain medication, can help two immunotherapy drugs work better against advanced liver cancer that has spread. The goal is to see if this combination can better control the cancer's growth and spread. Resear…

This early-stage study is testing whether infusions of donor stem cells are safe for young adults and children with dilated cardiomyopathy, a condition where the heart muscle is weakened and enlarged. Researchers will give participants three monthly intravenous infusions and moni…

This study aims to understand the best ways to treat people with hemophilia A whose immune systems have developed 'inhibitors' that block standard treatments. Researchers will observe 120 male participants for up to 5 years as they receive different combinations of immune toleran…

This study is testing whether doing handgrip exercises at home for 8 weeks can help improve blood pressure in people with chronic kidney disease (CKD). Researchers will enroll 50 adults with moderate CKD who don't exercise regularly to perform the grip training three times per we…

This study is testing whether a 12-month course of oral medications can help keep cancer from coming back in children and young adults with high-risk solid tumors. After finishing standard treatment, participants take a combination of drugs (sirolimus, celecoxib, and low-dose che…

This early-stage trial is testing a new, personalized vaccine for triple-negative breast cancer (TNBC). The vaccine is custom-made from a piece of a patient's own tumor and is designed to teach their immune system to recognize and attack the cancer. Researchers are studying the v…

This study is testing an investigational drug called eptacog beta to see if it can safely and effectively treat and prevent serious bleeding episodes in people with Glanzmann Thrombasthenia, a rare inherited bleeding disorder. Six participants with a history of severe bleeding wi…

This early-stage study is testing a combination of two drugs, cabozantinib and enfortumab vedotin, for advanced bladder cancer that has spread. The main goal is to find the safest and most effective dose. The study will also look for early signs that the treatment can shrink tumo…

This study is testing a two-drug combination (acalabrutinib and obinutuzumab) for people with untreated, slow-growing non-Hodgkin lymphomas. The goal is to see if this approach can effectively control the cancer, improve quality of life, and determine if patients who achieve a co…

This study is testing the safety of adding a wearable device called Optune to standard radiation and chemotherapy for adults with brainstem gliomas. The device creates low-intensity electric fields that may interfere with cancer cell division. Researchers will monitor 10 patients…

This study is testing if adding a hormone called progesterone to standard hormone therapy helps transgender women. Researchers want to see if it improves breast development, sleep quality, and mental well-being, while also checking for any effects on heart health. The study will …

This study is testing a three-drug combination as a long-term maintenance therapy for patients with high-risk multiple myeloma. The goal is to see if this treatment can help keep the cancer under control for longer after a stem cell transplant. The study will enroll about 34 adul…

This study is testing whether a shorter, more intense course of proton radiation therapy can effectively control the growth of non-cancerous brain tumors. It aims to see if this approach can stop tumor progression for at least three years while potentially reducing side effects a…

This study is testing if a wearable continuous glucose monitor (CGM) is better than the standard finger-prick method for managing blood sugar in people with Type 1 diabetes while they are in the hospital. Researchers want to see if the CGM helps keep blood sugar in a safe range m…

This early-stage study is testing a personalized vaccine made from a patient's own tumor cells. It aims to see if the vaccine, given alone or with an immunotherapy drug (pembrolizumab), is safe and can help the immune system fight advanced head and neck cancer that has returned o…

This study tests a community health worker program designed to improve heart health in young, low-income migrant farmworker women. The program provides peer support and helps connect women to local resources, aiming to reduce stress, social isolation, and risk factors like high b…

This study is testing two different home-based therapy programs delivered via video calls (telemedicine) for infants with cerebral palsy. The goal is to see if parents, guided remotely by therapists, can help improve their baby's arm and hand movement and function. Researchers wi…

This study is testing whether a 12-week sleep coaching program can help young adults with type 1 diabetes improve their sleep habits and, in turn, better control their blood sugar levels. Researchers will compare the coaching program to standard diabetes education to see which is…

This study tests whether an immunotherapy drug called toripalimab can help prevent cancer from returning after surgery in people with high-risk colon cancer that has a specific genetic feature. About 40 patients who have had their colon cancer surgically removed will receive the …

This study is testing a new, non-invasive wearable patch that listens to swallowing sounds. It aims to help doctors better detect and understand swallowing difficulties (dysphagia) in people who have had a stroke. The patch is placed on the chin during a standard swallowing test …

This study is testing whether a simple blood test can help emergency room doctors decide when a patient with a mild head injury really needs a CT scan. Researchers will enroll 350 adults with mild head injuries and randomly give some doctors the blood test results while others ma…

This study is testing a new, non-invasive ultrasound device called Velacur to see if it can accurately detect fatty liver disease in children and teens. Researchers want to see if this quick, bedside test can work as well as current gold-standard methods like MRI or liver biopsy,…

This study is testing new computer software designed to find a hidden, irregular heartbeat called atrial fibrillation (AF) using data from common wrist-worn devices like smartwatches. Researchers are enrolling 500 people who recently had a stroke to see if the software is as reli…

This study is testing a special type of MRI scan to see if it can help doctors better target proton beam radiation therapy for children with aggressive brain tumors. The scan looks at the tumor's chemical activity without needing an injection. Researchers want to see if this deta…

This study aims to test if a simple eye-tracking test can help screen 9-month-old infants for autism spectrum disorder and other developmental delays. Researchers will measure how babies look at social scenes during a pediatric visit and track their development until age 2. The g…

This study is testing a new, non-invasive handheld scanner that uses red light to take detailed pictures of skin lesions. The goal is to see if this technology can help doctors better diagnose skin cancer and other skin conditions without needing a biopsy first. Researchers will …

This study aims to find out if giving regular blood transfusions during pregnancy can prevent health crises and pregnancy complications in women with sickle cell disease. Researchers will compare two groups: one receiving scheduled transfusions and another receiving standard care…

This study is testing a program designed to help create smoke-free homes in rural tribal communities. The goal is to reduce people's exposure to secondhand smoke from commercial tobacco, which can help prevent cancer. Researchers will compare the program's effectiveness against u…

This study is testing if a single dose of the antibiotic azithromycin can clear the bacteria that causes meningitis from people who carry it without being sick. Researchers are enrolling 1120 university students who test positive for carrying the bacteria. The goal is to prevent …

This study is testing whether a gentle, non-invasive brain stimulation technique can weaken the formation of fear memories right after a distressing experience. Researchers at Emory University are enrolling 66 people to see if this approach can reduce the risk of developing Post-…

This study aims to help families in Cambodia switch from traditional wood/charcoal stoves to cleaner electric induction stoves to prevent harmful indoor air pollution. Researchers will test different strategies to encourage families to adopt and regularly use the new stoves acros…

This study is testing whether working with a personal pain coach after sports injury surgery helps people manage their pain better. The coaches teach mindfulness and other non-drug techniques, coordinate care, and provide education on opioid safety. Researchers will compare 150 p…

This study is testing whether playing simple online games like Connect 4 and Uno with family and friends can help older adults feel less lonely and more socially connected. Researchers are enrolling 124 adults aged 50-85, including some with mild memory concerns, to play games th…

This study is testing a new online support program designed for people with colorectal cancer who are receiving chemotherapy and their primary caregivers. The 8-week program aims to help manage common and distressing symptoms like severe fatigue, pain, depression, sleep problems,…

This study is testing a new group program designed to support the mental health of Ethiopian and Eritrean young adults in Atlanta. The program, called Weyera, focuses on building resilience through weekly sessions that teach coping skills and provide a supportive space. Researche…

This early-stage study aims to find out if it is safe to give palliative radiation therapy at the same time as a cancer drug called lurbinectedin. The trial is for adults with extensive stage small cell lung cancer that has spread and worsened after initial chemotherapy. Research…

This study is testing a phone-based system designed to help people with heart failure manage their symptoms at home. The system calls patients daily to check their symptoms and provides automated coaching advice. Researchers want to see if this approach helps patients feel better…

This study compares two approaches to voice therapy for people with voice problems like muscle tension dysphonia or vocal cord lesions. Researchers want to see if starting therapy with real conversation practice works better than traditional step-by-step exercises. The study will…

This study is testing whether a special group training program can help teens with sickle cell disease manage their chronic pain and improve their daily lives. The program, delivered over video calls, teaches skills to strengthen both the mind and body. Researchers will compare t…

This study is testing an online training program designed to help people who have recently become caregivers for a loved one with dementia. The program uses weekly group video sessions and online materials to teach practical skills and build confidence. Researchers want to see if…

This study is testing whether giving teenagers extra doses of a common steroid (dexamethasone) after spinal fusion surgery for scoliosis helps them recover better. Researchers want to see if the extra medicine reduces pain, cuts down on the need for strong opioid painkillers, les…

This study is testing whether cutting a small chest muscle during shoulder replacement surgery helps patients feel less pain and move their arm better afterward. Researchers will compare two groups: one that gets the muscle release and one that doesn't. The goal is to find the be…

This study is testing a long-acting numbing medicine (EXPAREL) to see if it provides better pain relief after ankle replacement surgery compared to a standard numbing medicine. Researchers will measure how much pain people feel and how many opioid painkillers they need after thei…

This study is testing if a shorter, lower dose of steroids (dexamethasone) after brain tumor surgery can reduce side effects like high blood sugar and poor wound healing, without increasing the risk of dangerous brain swelling. It will compare a 4-day steroid schedule to the stan…

This study is testing if giving a common chemotherapy drug (oxaliplatin) over 6 hours instead of the usual 2 hours can reduce or delay painful nerve damage in patients with gastrointestinal cancers. The goal is to help patients stay on their full, planned chemotherapy doses longe…

This study is testing whether mindfulness training helps college athletes recover better after surgery for a sports injury. Researchers will compare 40 injured athletes who learn mindfulness skills to those who receive standard recovery instructions. They will measure pain levels…

This study is testing an online course designed to help family and friends caring for someone with dementia. The course teaches practical skills for navigating complex healthcare, legal, financial, and social service systems. Researchers want to see if the course improves caregiv…

This study is testing if a medication called L-DOPA can help people with depression who also have high inflammation and a specific symptom called anhedonia, which is the inability to feel pleasure. Seventy adults with depression will take either L-DOPA or a placebo for eight week…

This small pilot study is testing whether a personalized, home-based exercise program delivered online can help reduce common and difficult symptoms like fatigue, pain, sleep problems, and depression in women who have finished treatment for gynecologic cancers. Researchers will e…

This study is testing whether a nerve block procedure can reduce pain caused by radiation therapy during anal cancer treatment. The procedure involves injecting numbing medicine near the tailbone to block pain signals. Researchers want to see if this helps patients complete their…

This study is creating and testing a new support program designed to help Black transgender women cope with the psychological distress caused by chronic stigma and discrimination. The program involves weekly group sessions, online educational materials, and social resources, all …

This study is testing whether a gentle, non-invasive device that stimulates nerves in the ear can help reduce pain in children hospitalized for sickle cell disease pain crises. Researchers want to see if this approach is practical and acceptable for kids, and if it shows early si…

This study is testing whether a safe, non-drug therapy can ease the chronic pain and headaches common in Gulf War Veterans. About 130 veterans will use a small, FDA-cleared device that delivers gentle electrical stimulation through the ear for six weeks. Researchers will use brai…

This study is testing a new group program designed to help reduce burnout and improve well-being for cancer center staff. 80 employees like nurses and doctors will be randomly assigned to either try the 4-session compassion and mindfulness program or continue with their usual res…

This study aims to find the best premedication to reduce allergic reactions to a drug called motixafortide, which helps collect stem cells for a transplant in multiple myeloma patients. It will compare the standard steroid, dexamethasone, against another steroid, methylprednisolo…

This study is testing whether a 6-week online skills program can help improve sleep for older adults living with memory loss or dementia and the people who care for them. Researchers want to see if teaching sleep techniques together via video calls is practical and helpful for bo…

This study is testing whether a 12-week, home-based exercise program delivered virtually can help improve memory, attention, and thinking problems in adolescent and young adult brain tumor survivors. Researchers will enroll 60 participants to see if regular, guided workouts are f…

This study is testing whether online physical therapy can help children and young adults recover strength and quality of life after bone marrow transplants. Participants aged 8-23 will have twice-weekly video sessions with a physical therapist for 12 weeks, using provided exercis…

This study is testing whether acupuncture or virtual acupressure can prevent severe joint pain caused by a common breast cancer medication. It focuses on Non-Hispanic Black postmenopausal women with early-stage breast cancer, as they are more likely to experience this side effect…

This study is testing whether a short, low-dose course of steroids (methylprednisolone) can help patients manage pain after foot or ankle surgery with fewer opioid painkillers. Researchers will enroll 180 patients to see if the steroid pack reduces pain, nausea, and overall opioi…

This research aims to understand how specific brain areas influence difficult decision-making in people with depression. Researchers will recruit 500 participants, including people with depression and healthy volunteers, to play game-like tasks while receiving safe, non-invasive …

This study aims to understand if combining two existing therapies—prism adaptation training (wearing special glasses) and mild electrical stimulation—can better help people recover from spatial neglect and walking difficulties after a stroke. Researchers will test these methods o…

This study aims to understand if a person's lung volume influences how their throat collapses during a key sleep apnea surgery evaluation. Researchers will recruit 200 adults with obstructive sleep apnea who are already scheduled for a standard pre-surgical throat exam under seda…

This study is testing whether a simpler, easier-to-read survivorship care plan helps Black and African American men who have finished treatment for prostate cancer. Researchers want to see if this tailored plan helps patients understand their follow-up care and manage long-term s…

This study aims to better understand why some children are born with a high genetic risk for cancer. Researchers will follow children with these inherited conditions and their family members over time, collecting health information and samples. The goal is to learn how these cond…

This study aims to find the best way to train early intervention therapists who work with young children showing communication delays or signs of autism. Researchers will compare two different training approaches for a proven therapy program called Project ImPACT. The study will …

This study aims to understand why people with bipolar disorder are at such high risk for suicide. Researchers will look at how factors like childhood trauma, drug use, and aggressive impulses might lead to suicidal thoughts and actions. They are also testing a 6-week group therap…

This study is testing whether easy-to-understand educational materials can help newly diagnosed African American prostate cancer patients better comprehend their treatment options and potential side effects. Researchers will interview 210 patients to see if these materials reduce…

This study aims to understand how mental stress affects the heart and blood vessels in post-menopausal women who have chest pain due to problems with their heart's smallest blood vessels. Researchers will compare 150 women across three groups: those with this condition, those wit…

This study aims to understand how the nicotine strength and flavor (acidity) of nicotine pouches affect how much young adults like them and how addictive they might be. Researchers will test different pouch formulas on 84 current users to measure appeal and potential for misuse. …

This study aims to understand how the ability to adjust walking patterns relates to memory problems in older adults. Researchers will observe 10 participants with mild cognitive impairment or Alzheimer's disease, using a special treadmill to test walking adaptation. The goal is t…

This study aims to understand why people with chronic kidney disease (CKD) often experience a sharp rise in blood pressure during exercise, which can limit their ability to be active. Researchers will measure nerve and blood vessel responses in 156 participants, some with CKD and…

This study is testing whether a new type of PET/CT scan can better detect damage to neck blood vessels caused by radiation therapy for head and neck cancers. Researchers will compare the new scan to the standard scan in about 20 patients before and after their radiation treatment…

This study aims to see if drinking pasteurized milk containing inactive H5 bird flu particles leads to the virus being detected in nose or throat swabs. Healthy adults will drink a small amount of specially prepared milk and provide swab samples. The results will help public heal…

This study aims to understand how the immune system responds to the flu virus and how the virus spreads from person to person. Healthy adult volunteers will be intentionally exposed to a specific flu strain in a controlled hospital setting and closely monitored. The information g…

This study aims to find the best way to write messages that invite patients to join medical research. It will test different message styles sent through a patient portal to see which ones get more people interested. The goal is to help future studies find participants more easily…

This study aims to understand if doxycycline, a common antibiotic used to prevent sexually transmitted infections, also affects body-wide inflammation and the community of bacteria living in the gut. It will enroll 200 healthy men, both with and without HIV, who are already takin…

This study aims to learn why some damaged hearts develop dangerous, fast rhythms called ventricular tachycardia (VT). Researchers will use a special catheter to measure tiny electrical signals in the heart muscle of 10 patients already scheduled for a standard VT treatment proced…

This study aims to understand how well lymphoma patients' immune systems respond to flu and COVID vaccines. Researchers will measure antibody levels and immune cells in 200 patients with various lymphoma types, comparing them over time. The goal is to learn how cancer treatments …

This study creates a registry to track how new FDA-approved Alzheimer's drugs work in real-world settings across Georgia. Researchers will follow 735 Medicare patients with early Alzheimer's who receive these anti-amyloid medications during regular clinic visits. The goal is to u…

This study aims to better understand achalasia, a disorder where the valve between the esophagus and stomach doesn't open properly. Researchers will use a new imaging probe to measure how the valve works and check for muscle scarring in 80 adult patients. The goal is to learn mor…