Could a single dose of MDMA supercharge PTSD therapy?
NCT ID NCT07288151
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single dose of MDMA, given alongside two weeks of daily exposure therapy, can reduce PTSD symptoms more than therapy alone. About 95 adults with PTSD will take either MDMA or a placebo during one therapy session. Researchers will check symptom changes one month later using a standard interview.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MDMA (3,4-methylenedioxymethamphetamine)
What this could lead to
If successful, this could point toward a faster, more effective treatment for PTSD by combining a single dose of MDMA with intensive therapy.
What could go wrong
This is an early Phase 2 trial with only 95 participants, so results may not apply to everyone. MDMA can cause side effects like increased heart rate or anxiety, and the placebo group may show similar improvement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Emory Brain Health Center
RECRUITINGAtlanta, Georgia, 30329, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••