Can a therapy that tackles both PTSD and everyday stress help those most at risk?
NCT ID NCT07714083
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This pilot study tests a version of cognitive processing therapy (CPT) that has been adapted to also address stress from lived experiences, such as discrimination or identity-related challenges. The trial enrolls sexual and gender minority adults with PTSD who report distress from these experiences. Participants receive either standard CPT or the adapted version (CPT-LEAP) to see if the new approach better reduces PTSD symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a modified form of cognitive processing therapy called CPT-LEAP that addresses both PTSD and stress from lived experiences
- What this could lead to
- If successful, this could point toward a more effective PTSD treatment tailored for sexual and gender minorities, potentially reducing health disparities.
- What could go wrong
- This is a small pilot study with only 52 participants, so results may not apply broadly. The modified therapy may not prove more effective than standard CPT.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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VA Boston Healthcare System
Jamaica Plain, Massachusetts, 02130, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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