Boston University

This study tests a 5-session virtual program called MATTER for 256 people living with HIV and substance use disorders. The program uses text messages and coaching to help reduce shame and stigma, improve self-care, and support HIV medication adherence. The goal is to help more pa…

This study tests whether a combination cream (5-fluorouracil plus calcipotriene) applied for just 7-14 days can effectively clear two types of low-risk skin cancer: superficial basal cell carcinoma and squamous cell carcinoma in situ. About 200 adults with these cancers will be r…

This study aims to help people with HIV stay in treatment, especially during the first six months when many stop coming to appointments. Researchers will create and test a toolkit that includes risk assessments, a treatment roadmap, and a WhatsApp support tool. About 30,000 patie…

This study is testing a new, painless light-based device (SFDI) to measure skin thickness in people with scleroderma, an autoimmune disease that causes skin hardening. The goal is to see if this device is more accurate than the current method, which involves pinching the skin. Re…

This study compares two short counseling programs for veterans who have experienced intimate partner violence (IPV) in the past year. One program offers up to 8 sessions focused on strengths and empowerment, while the other is a single session providing support and resources. Res…

This study tests whether wearing virtual reality (VR) glasses during oral surgery can lower anxiety and reduce the amount of sedation medicine needed. About 80 adults having non-emergency oral surgery will be randomly assigned to either watch a relaxing VR video or wear plain pro…

This study tests whether adding a brief writing exercise called AWARE to standard PTSD treatments (CPT or PE) can improve how patients and therapists communicate, leading to better results. Researchers will enroll 54 adults with PTSD to see if AWARE is acceptable, feasible, and h…

This study looks at whether vitamin K supplements can help people with knee osteoarthritis. Researchers will test different types and doses of vitamin K in 55 adults aged 60 and older who have knee osteoarthritis. The goal is to see if vitamin K improves certain markers in the bl…

This study tests whether adding memory-support techniques to standard PTSD therapy helps people learn and remember key therapy content. About 100 adults with PTSD will receive either standard therapy or therapy with extra memory aids. The goal is to see if better memory of therap…

This study tests a new 3D-printed device that helps dentists give numbing injections more accurately. Traditional numbing shots for lower teeth often miss their target, failing up to 45% of the time. The device uses a 3D scan to guide the needle to the right spot, aiming to reduc…

This study aims to find the most effective way to manage pain in young children after they have dental surgery under general anesthesia. Researchers will compare three different pain medication schedules using common over-the-counter drugs: ibuprofen alone, alternating ibuprofen …

This study is testing a stress management program designed to help women in Vietnam who have breast or gynecologic cancer. The program, called Self-Help Plus, aims to reduce feelings of depression and anxiety and improve quality of life. Researchers will compare the program to st…

This study looks at whether changing how your teeth meet (your bite) can affect your balance and walking. Researchers will use dental splints or dentures to temporarily alter bite height in healthy adults aged 30–45 and denture wearers aged 50–65. They will measure body movement …

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to learn if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe pre-eclampsia. The goal is to pr…

This study looks at existing medical records from about 7 million people with HIV in South Africa to understand how different ways of delivering HIV treatment are working. Researchers want to see how many people are using these models, how well they control the virus, and what th…

This study aims to see how well wrist-worn activity trackers measure the intensity of movement and exercise. Researchers will have 54 adults wear these devices while performing structured and everyday tasks, comparing the tracker data to a precise breathing measurement method. Th…

This study looks at medical records from up to 1 million people in Malawi to see how different ways of delivering HIV treatment are working. The goal is to find out which models help more patients stay healthy and use resources wisely. No new treatments are being tested—just exis…

This study follows 150 adults with advanced HIV in South Africa after they leave the hospital. Researchers want to see if patients successfully return to their local clinic for ongoing HIV treatment and identify where the care process breaks down. The goal is to find ways to impr…

This study reviews existing medical records from about 1.2 million people with HIV in Zambia to see how different ways of delivering care are working. Researchers want to understand which models help more people stay on treatment and achieve viral suppression. No new treatments a…

This study tests whether a telehealth interview before a dental appointment helps youth with intellectual or developmental disabilities (IDD) and their caregivers have a smoother visit. About 50 participants will be randomly assigned to get a video call with the dentist beforehan…