Boston University

This study aims to help people with HIV stay in care, especially during the first six months after starting or restarting treatment—a time when many drop out. Researchers are creating a toolkit that includes a risk assessment, a menu of support options, a treatment roadmap, and a…

This study tests whether a combination of two creams (5-fluorouracil and calcipotriene) can clear low-risk skin cancers in just 1-2 weeks instead of the usual 4 weeks. About 200 adults with superficial basal cell carcinoma or squamous cell carcinoma in situ will apply the cream d…

This study tests a 5-session virtual program called MATTER for 256 people living with HIV and substance use disorders. The program uses text messages and coaching to address internalized stigma and shame, helping participants stay engaged in HIV care and achieve viral suppression…

This study is testing a new, painless light-based device (SFDI) to measure skin thickness in people with scleroderma, an autoimmune disease that causes skin hardening. The goal is to see if this device is more accurate than the current method, which involves pinching the skin. Re…

This study looks at whether different types and doses of vitamin K can improve knee osteoarthritis in people aged 60 and older. Researchers will measure changes in blood markers linked to joint health. The goal is to find the best vitamin K form and dose for easing osteoarthritis…

This study tests whether adding a brief writing task, called AWARE, to standard PTSD therapies (CPT or PE) helps patients and therapists communicate better. About 54 adults with PTSD will take part. The goal is to see if AWARE makes treatment more effective and satisfying.

This study tests a new 3D-printed device that guides numbing injections for dental procedures. The goal is to make the injection more accurate, reduce pain, and lower the chance of it not working. Ten adults needing a root canal on a lower tooth will try the device, and researche…

This study looks at how well different pain medicine plans work for young children after dental surgery done under general anesthesia. About 75 children will get either ibuprofen alone, ibuprofen and acetaminophen given at different times, or both medicines together. Caregivers w…

This study tests a stress management program called Vietnamese Self Help Plus (vSH+) for women with breast or gynecologic cancer in Vietnam. The goal is to see if it helps reduce anxiety and depression and improves quality of life. About 285 participants will be randomly assigned…

This study compares two short counseling programs for veterans who have experienced intimate partner violence (IPV) in the past year. One program offers up to 8 sessions focused on strengths and empowerment, while the other is a single session providing support and resources. Res…

This study tests whether wearing virtual reality (VR) glasses during oral surgery can lower anxiety and reduce the amount of sedation medicine needed. About 80 adults having non-emergency oral surgery will be randomly assigned to either watch a relaxing VR video or wear plain pro…

This study tests whether adding memory-support techniques to standard PTSD therapy helps people learn and remember key therapy content. About 100 adults with PTSD will receive either standard therapy or therapy with extra memory aids. The goal is to see if better memory of therap…

This study tests whether a telehealth interview before a dental appointment helps youth with intellectual or developmental disabilities (IDD) and their caregivers have a smoother visit. About 50 participants will be randomly assigned to a telehealth pre-visit or standard care. Re…

This study follows 150 adults with advanced HIV who are in the hospital in South Africa. Researchers want to see if patients get the follow-up care they need after leaving the hospital, including continuing their HIV medication. The goal is to find where the system fails and how …

This study reviews medical records from up to 1 million people with HIV in Malawi to see how different ways of delivering treatment are working. The goal is to understand which models help patients stay healthy and use resources wisely. No new treatments are tested, and no direct…

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to learn if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe pre-eclampsia. The goal is to pr…

This study looks at medical records from over a million people in Zambia to see how different ways of delivering HIV care are working. The goal is to understand which models help more patients stay on treatment and achieve viral suppression. No new treatments are being tested; in…

This study looks at how changes in the way your teeth come together (your bite) might affect your balance and walking. Researchers will use dental splints or dentures to temporarily change the bite height in healthy adults aged 30-45 and denture wearers aged 50-65. They will meas…

This study reviews medical records from about 7 million people with HIV in South Africa to understand how different ways of delivering HIV care are working. Researchers want to see how many people use these services, how well they control the virus, and what the costs are. No new…

This study aims to see how well wrist-worn activity trackers measure the intensity of movement and exercise. Researchers will have 54 adults wear these devices while performing structured and everyday tasks, comparing the tracker data to a precise breathing measurement method. Th…