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New light imaging could replace the pinch test for scleroderma patients

NCT ID NCT07090226

Recruiting now Knowledge-focused Sponsor: Boston University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study is testing a new, non-invasive imaging technique called spatial frequency domain imaging (SFDI) to measure skin thickness in people with scleroderma. Currently, doctors use a subjective pinch test, but SFDI uses light scattering to measure collagen in the skin more accurately. The study will compare SFDI results with the standard pinch test and ultrasound in 65 participants, including healthy volunteers, to see if this new method is better at tracking skin changes over time.

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Conditions

The condition(s) this trial relates to.

diffuse cutaneous systemic sclerosis diffuse scleroderma systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIFFUSE CUTANEOUS SCLERODERMA SYSTEMIC SCLERODERMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shapiro Outpatient Rheumatology Clinic at Boston Medical Center

    RECRUITING

    Boston, Massachusetts, 02118, United States

    Contact

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