Can a viagra drug heal scleroderma finger sores?

NCT ID NCT01295736

Completed Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether sildenafil (the drug in Viagra) can help heal painful finger ulcers in people with scleroderma, a disease that damages blood vessels. 84 participants took either sildenafil or a placebo three times daily for 90 days. The main goal was to see if the ulcers healed faster with sildenafil.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sildenafil (20 mg three times daily)
What this could lead to: If it works, sildenafil could speed up healing of painful finger ulcers in people with scleroderma, improving hand function and quality of life.
What could go wrong: This is a completed Phase 3 trial with only 84 participants. Sildenafil may not heal ulcers faster than placebo, and side effects like headache or flushing are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

diffuse scleroderma systemic sclerosis ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC SCLERODERMA

Contacts and locations

Locations

CHU Dijon

Dijon, Côte d'Or, 21000, France
CHU Dupuytren / Médecine Interne

Limoges, Haute Vienne, 87042, France
CHU Dupuytren / dermatology

Limoges, Haute Vienne, 87042, France
CHU de Caen

Caen, Calvados, 14033, France
CHU de Reims

Reims, Marne, 51092, France
CHU de Rennes

Rennes, Ile Et Vilaine, 35203, France
Cochin Hospital

Paris, Île-de-France Region, 75014, France
Cochin Hospital / Médecine Interne

Paris, Île-de-France Region, 75014, France
Groupe Hospitalier Paris Saint Joseph

Paris, Île-de-France Region, 75674, France
Hautepierre Hospital

Strasbourg, Bas-Rhin, 67098, France
Hôpital Edouard Herriot

Lyon, 69437, France
Jean Verdier Hospital

Bondy, Île-de-France Region, 93130, France
La Pitié - Salpétriêre Hospital

Paris, Île-de-France Region, 75013, France
Nord Hospital

Marseille, Bouches du Rhone, 13915, France
Saint Antoine Hospital

Paris, Île-de-France Region, 75571, France
St Louis Hospital

Paris, PARIS, 75010, France
University Hospital, Amiens

Amiens, Somme, 80000, France
University Hospital, Fort de France

Fort de France, Martinique, 97 261, France
University Hospital, Grenoble

Grenoble, Isère, 38043, France
University Hospital, Lille

Lille, Nord, 59037, France
University Hospital, Nantes

Nantes, Loire-Atlantique, 44000, France
University Hospital, Nice

Nice, Alpes-Maritimes, 06000, France
University Hospital, Rouen

Rouen, Seine-Maritime, 76000, France
University Hospital, Tours

Tours, Indre-et-Loire, 37000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.