Can a viagra drug heal scleroderma finger sores?

NCT ID NCT01295736

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether sildenafil (the drug in Viagra) can help heal painful finger ulcers in people with scleroderma, a disease that damages blood vessels. 84 participants took either sildenafil or a placebo three times daily for 90 days. The main goal was to see if the ulcers healed faster with sildenafil.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sildenafil (20 mg three times daily)

What this could lead to

If it works, sildenafil could speed up healing of painful finger ulcers in people with scleroderma, improving hand function and quality of life.

What could go wrong

This is a completed Phase 3 trial with only 84 participants. Sildenafil may not heal ulcers faster than placebo, and side effects like headache or flushing are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse scleroderma systemic sclerosis ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Dijon

    Dijon, Côte d'Or, 21000, France

  • CHU Dupuytren / Médecine Interne

    Limoges, Haute Vienne, 87042, France

  • CHU Dupuytren / dermatology

    Limoges, Haute Vienne, 87042, France

  • CHU de Caen

    Caen, Calvados, 14033, France

  • CHU de Reims

    Reims, Marne, 51092, France

  • CHU de Rennes

    Rennes, Ile Et Vilaine, 35203, France

  • Cochin Hospital

    Paris, Île-de-France Region, 75014, France

  • Cochin Hospital / Médecine Interne

    Paris, Île-de-France Region, 75014, France

  • Groupe Hospitalier Paris Saint Joseph

    Paris, Île-de-France Region, 75674, France

  • Hautepierre Hospital

    Strasbourg, Bas-Rhin, 67098, France

  • Hôpital Edouard Herriot

    Lyon, 69437, France

  • Jean Verdier Hospital

    Bondy, Île-de-France Region, 93130, France

  • La Pitié - Salpétriêre Hospital

    Paris, Île-de-France Region, 75013, France

  • Nord Hospital

    Marseille, Bouches du Rhone, 13915, France

  • Saint Antoine Hospital

    Paris, Île-de-France Region, 75571, France

  • St Louis Hospital

    Paris, PARIS, 75010, France

  • University Hospital, Amiens

    Amiens, Somme, 80000, France

  • University Hospital, Fort de France

    Fort de France, Martinique, 97 261, France

  • University Hospital, Grenoble

    Grenoble, Isère, 38043, France

  • University Hospital, Lille

    Lille, Nord, 59037, France

  • University Hospital, Nantes

    Nantes, Loire-Atlantique, 44000, France

  • University Hospital, Nice

    Nice, Alpes-Maritimes, 06000, France

  • University Hospital, Rouen

    Rouen, Seine-Maritime, 76000, France

  • University Hospital, Tours

    Tours, Indre-et-Loire, 37000, France