Could a single infusion of supercharged immune cells tame incurable autoimmune diseases?

This early study is testing a new treatment called CD19 CAR-T therapy for people with severe autoimmune diseases like lupus and scleroderma that haven't improved with standard medications. The therapy involves taking a patient's own immune cells, reprogramming them to target and destroy faulty immune cells, and infusing them back. The main goals are to check safety and find the right dose, with 20 participants enrolled.