Stress and the heart: new study targets women with hidden chest pain

NCT ID NCT05401630

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how mental stress impacts the small blood vessels of the heart in postmenopausal women with coronary microvascular dysfunction (CMD). Researchers will measure heart activity, stress responses, and daily symptoms in 150 women using imaging, questionnaires, and home monitoring. The goal is to understand why stress triggers chest pain in these women, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal how mental stress worsens heart symptoms in women with small vessel disease, pointing toward better management strategies.

What could go wrong

This is an observational study, not a treatment trial. It will not directly improve health, and results may not apply to all women.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Angina Pectoris coronary artery disorder coronary microvascular disorder Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Emory Clinic

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Emory Saint Joseph's Hospital

    RECRUITING

    Atlanta, Georgia, 30308, United States