Stress and the heart: new study targets women with hidden chest pain

NCT ID NCT05401630

Recruiting now Knowledge-focused Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how mental stress impacts the small blood vessels of the heart in postmenopausal women with coronary microvascular dysfunction (CMD). Researchers will measure heart activity, stress responses, and daily symptoms in 150 women using imaging, questionnaires, and home monitoring. The goal is to understand why stress triggers chest pain in these women, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how mental stress worsens heart symptoms in women with small vessel disease, pointing toward better management strategies.
What could go wrong: This is an observational study, not a treatment trial. It will not directly improve health, and results may not apply to all women.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Angina Pectoris coronary artery disorder coronary microvascular disorder Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-MENOPAUSE

Contacts and locations

Locations

Emory Clinic
RECRUITING

Atlanta, Georgia, 30322, United States
Emory Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Emory Hospital Midtown
RECRUITING

Atlanta, Georgia, 30308, United States
Emory Saint Joseph's Hospital
RECRUITING

Atlanta, Georgia, 30308, United States

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