Emory University

This study is testing whether adding mental health support to regular diabetes care helps adults with type 1 diabetes. Participants will complete surveys about their mood and health habits every six months. Some will also work with a mental health coach by phone or video to set p…

This study is testing whether a combination of daily oral medications can shrink tumors in children whose cancers have come back or have not responded to standard treatments. The treatment involves taking several pills daily, including sirolimus, celecoxib, and alternating low do…

This early-stage study is testing the safety of a new two-part radiation treatment for men whose prostate cancer has returned after surgery. First, patients receive a targeted external beam radiation guided by a special PET scan. Then, they receive a radioactive drug designed to …

This study is testing if adding a common, low-cost blood pressure medication called propranolol to standard immunotherapy helps people with advanced bladder cancer. Six participants will receive either immunotherapy alone or immunotherapy plus propranolol. The main goal is to see…

This study is testing if giving more doses of a drug called abatacept can better prevent a dangerous complication called graft-versus-host disease (GVHD) in children and teens. The trial includes 30 young patients with serious non-cancerous blood diseases who are receiving a stem…

This study is testing whether combining two immunotherapy drugs, vidutolimod and nivolumab, can help the body's immune system find and kill prostate cancer cells that have spread. It is for men whose cancer has stopped responding to standard hormone therapy and chemotherapy. The …

This study is testing whether combining two existing drugs, pembrolizumab and cabozantinib, can help control advanced head and neck cancer that has come back or spread. It will involve about 36 patients whose cancer cannot be removed by surgery. The main goal is to see how many p…

This study is testing if giving an immunotherapy drug called atezolizumab before surgery helps treat early-stage throat cancer caused by HPV. The drug aims to help the patient's own immune system attack the cancer. Researchers will give two doses to 20 patients, then check the tu…

This early study is testing whether daily progesterone injections can help control tumor growth in adults whose aggressive brain cancer (glioblastoma) has returned. Researchers want to find the safest dose and see if the treatment can stabilize the disease. The study involves a v…

This early-stage study is testing a new, cautious treatment strategy for patients with high-risk AL amyloidosis, a serious disease where abnormal proteins damage organs. Doctors are slowly adding different drugs, starting with isatuximab, to find the most effective combination pa…

This study is testing whether kidney transplant patients who have been stable on monthly IV infusions for over two years can safely switch to weekly self-administered injections. Researchers want to see if the new injection method maintains kidney function as well as the current …

This early safety study is testing a new oral drug called tolinapant given alongside standard radiation therapy. It is for patients with locally advanced head and neck cancer who cannot receive the usual chemotherapy drug, cisplatin. The main goal is to see if the combination is …

This early-stage trial is testing the safety of combining two drugs—venetoclax and tocilizumab—for multiple myeloma that has returned or stopped responding to treatment. The study focuses on patients whose cancer has a specific genetic change called t(11;14). Researchers want to …

This study is testing if people with type 2 diabetes can safely keep taking their usual diabetes pills while in the hospital, instead of switching to insulin shots. It will compare blood sugar control and safety between the two approaches in 255 hospitalized patients. The goal is…

This study is testing whether customizing treatment based on specific blood protein levels can help people with coronary artery disease. Researchers are comparing personalized medication adjustments and lifestyle changes against standard care to see which approach better lowers r…

This early-stage study is checking if it's safe and practical to give testosterone replacement to men with low testosterone levels before they have major urinary system surgery. The goal is to see if this approach might improve recovery by potentially reducing hospital stays and …

This study is testing a new clinic program called CHIMES, designed to better connect HIV care with mental health services. It focuses on young Black gay and bisexual men living with HIV in Atlanta, a group that often faces barriers to getting mental health support. The goal is to…

This study is testing if taking the drug cabozantinib for 12 weeks before surgery can shrink advanced kidney tumors that have not spread. The goal is to see if this pre-surgery treatment helps control the cancer and makes surgery more effective. Researchers will measure tumor shr…

This pilot study is testing a 12-month lifestyle program designed to help people with mild memory problems. The program focuses on improving diet, physical activity, stress management, and brain health through group and individual activities, delivered both in-person and remotely…

This study is testing two different support programs to help teenagers with HIV in South Africa successfully move from pediatric to adult healthcare. It compares in-person support groups to a mobile phone-based program, aiming to see which helps teens stay on their medication and…

This study is testing a new combination of three drugs for people with advanced non-small cell lung cancer that has spread or come back after standard treatments failed. The goal is to see if mixing an immunotherapy drug, a drug that blocks tumor blood supply, and a chemotherapy …

This study is testing if two drugs, niraparib and panitumumab, work better together to treat advanced colorectal cancer that has spread. It involves about 26 people whose cancer has continued to grow despite prior treatment. The main goals are to see if the combination can stop o…

This study is testing whether a single dose of MDMA, combined with an intensive two-week therapy program, can help reduce PTSD symptoms. All 40 participants will receive the MDMA-assisted therapy during the treatment. Researchers want to see if adding MDMA makes the established t…

This study is testing if adding a common water pill (furosemide) to a specialized PET/CT scan can make the images clearer for men whose prostate cancer has returned. The pill may help flush radioactive tracer from the bladder, potentially revealing hidden cancer spots nearby. Res…

This study tests whether providing expectant parents with clear, factual information about vaccines during prenatal care can build their confidence and lead to more children getting their shots on time. It involves training prenatal care providers and offering extra support, like…

This small, early-stage study aimed to see if a specific type of exercise could help people with a very early warning sign for diabetes. Researchers planned to test whether high-intensity interval training (HIIT) was practical to study and could lower fasting blood sugar in inact…

This study is testing whether a smartphone game can help prevent HIV among adolescents in Kenya. About 900 teens aged 12-14 will receive phones with either an educational HIV prevention game or a regular game to compare outcomes. The goal is to see if playing the game increases k…

This study tests whether community workshops can help villages in rural Guatemala reduce the common practice of burning plastic waste at home. Researchers will compare 8 villages receiving the workshops to 8 villages that do not, focusing on 400 women who cook with wood and regul…

This study is testing whether a smartphone app can help men in rural southern U.S. communities get tested for HIV and other sexually transmitted infections (STIs) and start preventive medication (PrEP). About 470 participants will use the app and be assigned to different groups t…

This 2-year study is testing whether a diet very low in added sugars can prevent non-alcoholic fatty liver disease (NAFLD) in Hispanic children who are at high risk. Researchers are working with 103 children ages 6-9 who have overweight or obesity but don't yet have liver problem…

This study aims to find out if certain types of stitches or stitching techniques lead to less pain and better healing after hand or wrist surgery. Researchers will randomly assign 160 patients to receive different standard stitches during their operation. After surgery, they will…

This study is testing whether daily exposure to a special flickering light and sound, called gamma sensory flicker, is safe and can help reduce 'freezing of gait' in people with Parkinson's disease. Freezing of gait is when a person's feet feel stuck to the floor, which is a majo…

This small pilot study is testing whether a word game-based workbook can help people with type 2 diabetes learn how to better manage their condition. Researchers developed a workbook with puzzles and games that teach diabetes management concepts, focusing first on carbohydrate co…

This study aims to understand how the HPV vaccine creates such strong and long-lasting protection against cancer-causing viruses. Researchers will follow 17 healthy adults receiving the standard HPV vaccine schedule, collecting samples from their blood, saliva, lymph nodes, and b…

This study aims to understand how certain prostate cancer hormone treatments affect heart health. It will compare two different hormone drugs given alongside radiation therapy to see which might be safer for the heart. Researchers will use heart scans and blood tests to learn why…

This study aims to understand how the immune systems of adults aged 60 and older respond to the FDA-approved Moderna RSV vaccine. Researchers will collect detailed biological data from 14 participants to identify early signs of a strong immune response and learn how long protecti…

This early study aims to see if two new oral drugs, defactinib or VS-6766, can reach brain tumors in patients with glioblastoma. Researchers will give a single dose to 14 patients before their scheduled tumor removal surgery. The main goals are to measure how much drug gets into …

This research study aims to understand how autoimmune diseases like lupus develop by comparing immune cells from people with autoimmune conditions, people with infectious diseases, and healthy individuals. Researchers will collect blood and sometimes bone marrow samples from 2,50…

This study aims to understand how anemia (low red blood cells) and the blood transfusions used to treat it affect oxygen levels in the digestive systems of very small preterm babies. Researchers will observe 324 infants weighing 1250 grams or less to learn why some develop a seri…

This study is testing a new parenting program in Tanzania that includes both mothers and fathers. It aims to see if teaching couples about positive parenting, communication, and sharing household duties improves child development and family relationships. Community health workers…

This study aims to understand how gay, bisexual, and other men who have sex with men (MSM) choose to protect themselves from HIV and other sexually transmitted infections (STIs). Researchers will follow 1,275 men in Atlanta, Chicago, and San Diego for two years, asking them to co…

This study aims to understand how long a single dose of the approved Ebola vaccine provides immune protection. Thirty healthy adult volunteers will receive the vaccine and provide blood, lymph node, and bone marrow samples over a year. Researchers will track how the body's immune…