Emory University

This early-phase trial tests whether infusions of donor bone marrow stem cells (MSCs) are safe and can improve growth and bone health in 12 children aged 3–10 with severe osteogenesis imperfecta type 3. The study will monitor side effects, growth rates, fracture healing, and bone…

This early-stage trial tests a topical ointment called ACU-D1 for HPV-related vulvar and perianal lesions in people with HIV. Nine participants will apply the cream twice daily for 4 weeks. The main goal is to find the safest dose and see if the treatment can boost immune markers…

This study tests whether a virtual session with a peer recovery coach can help incarcerated adults with substance use disorders connect to addiction treatment and recovery resources. About 550 participants in jail will either get the coaching or just standard information. Researc…

This study tests whether baricitinib, an FDA-approved drug for other conditions, can keep HIV under control after participants stop their usual antiretroviral therapy (ART). Twenty people with well-controlled HIV will take baricitinib alongside ART for 26 weeks, then continue bar…

This study tests whether using a real-time continuous glucose monitor (CGM) can improve blood sugar control and reduce hospital readmissions in people with type 2 diabetes and acute heart failure. Researchers will follow 140 adults during their hospital stay and for three months …

This study will test a new device called the micro Sweat Test Patch (µSTP) that measures chloride levels in sweat to help diagnose and monitor cystic fibrosis (CF). Researchers will compare the new patch to the standard sweat test in 300 newborns, children, and adults with CF. Th…

This study tests a program called GBE (Ghya Bharaari Ekatra) designed to prevent intimate partner violence (IPV) in newly married couples. Researchers will enroll 1,700 couples living in slums in Mumbai and Pune, India, who have been married for one year or less. The goal is to s…

This study will test a mobile app called HealthMPowerment designed to help Black adolescents and young adults in Alabama take PrEP, a daily pill that prevents HIV. Ten teens and their adult supporters will use the app for a few weeks, and researchers will check if it's easy and a…

This study will test a smartphone app designed to help Black teenagers and young adults in Atlanta take their HIV prevention medication (PrEP) consistently. Researchers will work with 10 participants and their adult supporters to see if the app is easy to use and helpful. The goa…

This study will test whether a 4-week daily music therapy app can reduce chronic pain and improve quality of life in 25 youth with sickle cell disease. Participants will either use the app or receive standard educational materials. Researchers will also look at changes in immune …

This study tests whether doing simple handgrip exercises at home for 8 weeks can lower blood pressure in people with chronic kidney disease (CKD). Researchers will measure changes in resting blood pressure, blood vessel function, and stiffness. The study involves 50 adults aged 4…

This study tests whether adding suzetrigine (Journavx) to standard pain management can lower pain and reduce the need for opioid painkillers after total knee replacement. About 75 adults with knee arthritis will take the drug as part of their post-surgery care. The goal is to imp…

This study tests whether the psychedelic drug psilocybin, combined with talk therapy, can safely reduce PTSD symptoms in Georgia military veterans. 150 veterans will be randomly assigned to different therapy approaches to compare results. The goal is to see if this combination is…

This study tests whether baricitinib, an anti-inflammatory drug, can improve depression and cognitive symptoms in 30 male former football players aged 40-55 with at least 10 years of play. Participants take the drug every other week for 6 weeks, and researchers use brain scans an…

This study tests whether a virtual cognitive behavioral therapy for insomnia (CBT-I) program, called REPAIR Sleep, can improve sleep and emotional well-being in people with dementia and their live-in caregivers. Over 5 weekly video sessions, participants learn techniques like set…

This study tests a sleep program for people hospitalized after a leg injury that needed surgery. The program includes sleep medicine, melatonin, and sleep tips. Researchers want to see if it helps patients sleep longer and better, and if it reduces the need for strong painkillers…

This study tests a new, smarter electrical stimulation system to help people who have had a stroke walk better. The system uses a computer to adjust stimulation in real time, aiming to correct footdrop (when the foot drags). About 20 participants will compare this new system to a…

This study looks at whether a common diabetes medication (GLP-1 RA) can improve muscle strength and bone health in women over 65 with type 2 diabetes. About 20 participants will take the drug as part of their regular care and undergo tests like grip strength and bone density scan…

This study investigates why some chronic stroke survivors with slow walking speed improve after high-intensity interval training (HIIT) while others do not. Participants will undergo 12 weeks of supervised cycling sessions, along with MRI brain scans and walking tests before and …

This observational study will follow 2,500 people who had a brain hemorrhage and received minimally invasive surgery. Researchers want to see how well patients recover in real-world settings. The study does not test a new drug or procedure, but gathers data to improve future care…

This pilot study will test whether autism can be diagnosed in toddlers (16-36 months) using a telehealth protocol, instead of an in-person visit. Researchers will enroll 100 children from Georgia's early intervention program who are at moderate or high risk for autism. The goal i…

This study tests better ways to screen and treat cervical cancer in women living with HIV in Kenya, who face a much higher risk. Researchers will use HPV self-testing, care navigators, and a mobile app to help more women get diagnosed and treated. The goal is to find strategies t…

This study looks at how people with anxiety make decisions to avoid things that make them anxious. Researchers will use brain scans and phone tracking to see how avoidance behavior works in the lab and in real life. About 163 adults with and without anxiety will take part. The go…

This study will test a non-invasive brain stimulation method called temporal interference (TI) in 300 healthy volunteers and people with anxiety or PTSD. TI uses two weak electrical fields to target deep brain areas linked to fear and emotion without affecting the surface of the …

This study compares three computer programs designed to predict sepsis, a life-threatening reaction to infection. Researchers will test these programs on 1,200 adults arriving at the emergency room, but the predictions will not be shared with doctors or patients. The goal is to f…

This study tests whether point-of-care STI tests, which give results in about 10 minutes, can speed up treatment for pregnant women compared to standard lab tests. About 756 pregnant women at Grady Memorial Hospital will either get the rapid tests or standard testing. The goal is…