Ebola vaccine memory under the microscope: how long does it last?

NCT ID NCT06100913

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study gives 30 healthy adults a single dose of the approved Ebola vaccine (Ervebo) and tracks their immune responses over time using blood, lymph node, and bone marrow samples. The goal is to understand how long the body 'remembers' the vaccine, which could guide future booster schedules. It is not testing the vaccine's effectiveness against Ebola, but rather the durability of immune memory.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ebola vaccine (Ervebo)

What this could lead to

If successful, this could help determine how often booster shots are needed to maintain protection against Ebola.

What could go wrong

This is a small, early-phase study focused on immune response, not on preventing disease. Results may not predict real-world protection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Ebola hemorrhagic fever prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Hope Clinic of the Emory Vaccine Center

    Decatur, Georgia, 30030, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63130, United States