Ebola hope? favipiravir trial shows mixed results

NCT ID NCT02329054

First seen Nov 18, 2025 · Last updated Jun 21, 2026 · Updated 31 times

Summary

This study tested the antiviral drug favipiravir in 126 people with Ebola in Guinea. Participants received high doses of the drug for 10 days. The goal was to see if it could lower the death rate. Results suggested a possible benefit for patients with low to moderate virus levels, but not for those with high virus levels.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ALIMA Ebola care center

    Nzérékoré, Guinea

  • French Red Cross Ebola care center

    Macenta, Guinea

  • MSF Ebola treatment centre

    Gueckedou, Guinea

  • The caregivers treatment center

    Conakry, Guinea

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

favipiravir (an antiviral drug)

What this could lead to

If successful, this could provide a treatment option to reduce deaths from Ebola virus disease.

What could go wrong

This was a small, early-phase trial without a placebo group, so results are uncertain. The drug may not work for patients with high virus levels.

Conditions

The condition(s) this trial relates to.

Ebola hemorrhagic fever

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.