Could a short steroid course ease pain and nausea after bone surgery?

NCT ID NCT03661645

ENROLLING_BY_INVITATION Symptom relief Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Apr 10, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study looks at whether taking a 6-day course of the steroid methylprednisolone after common orthopedic surgeries (like joint replacement or fracture repair) can reduce pain, nausea, and improve movement compared to just getting a single dose of steroid during surgery. About 500 adults will be randomly assigned to either the standard single dose or the single dose plus the 6-day taper. The goal is to see if the longer course helps people recover more comfortably.

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Contacts and locations

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Locations

21 Ortho Lane

Atlanta, Georgia, 30329, United States
Emory Clinic A, Clifton Road Clinic

Atlanta, Georgia, 30322, United States
Emory Healthcare Orthopaedics and Spine Center

Atlanta, Georgia, 30329, United States

Conditions

Explore the condition pages connected to this study.

ORTHOPEDIC SURGERIES