New hope for head and neck cancer: drug plus radiation shows promise in early trial

NCT ID NCT05245682

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 19 times

Summary

This early-phase study tests whether combining the drug tolinapant with radiation therapy is safe and doable for people with head and neck cancer that hasn't been treated yet and has spread locally. Participants are those who can't take the standard chemo drug cisplatin. The goal is to see if this combo can kill more cancer cells without causing too many side effects.

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Contacts and locations

Locations

  • Emory University/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.