New drug combo shows promise in shrinking advanced kidney tumors before surgery

NCT ID NCT04393350

First seen Apr 26, 2026 · Last updated Jun 13, 2026 · Updated 11 times

Summary

This study tests whether giving two drugs—lenvatinib and pembrolizumab—before surgery can shrink tumors in people with locally advanced kidney cancer that hasn't spread to other organs. About 18 participants will receive the combination for 12 weeks before their operation. The goal is to see how many patients experience tumor shrinkage and to monitor side effects.

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Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.